BIIB vs ARGX vs AMGN Stock Comparison

Biogen, Argenx Se and Amgen Prices as of Oct 28, 2026 Peers: Industry group
BIIB Biogen Inc.
$244.05 +6.7% 1M +63.6% 1Y
Market cap
$36.08B
P/E
103.8x
Revenue (TTM)
$10.30B
Div. yield
–
Biotechnology Healthcare
2 wins
ARGX Argenx Se
$891.76 -8.3% 1M +6.6% 1Y
Market cap
$55.19B
P/E
29.1x
Revenue (TTM)
$5.82B
Div. yield
–
Biotechnology Healthcare
4 wins
AMGN Amgen Inc
$451.83 +8.1% 1M +54.7% 1Y
Market cap
$244.26B
P/E
27.9x
Revenue (TTM)
$38.10B
Div. yield
2.20%
Biotechnology Healthcare
5 wins

Head to Head

11 decided of 12

Amgen leads on 5 of the 12 questions below (Amgen 5, Argenx Se 4, Biogen 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionBIIBARGXAMGNLeader
Larger companyMarket capitalisation $36.08B $55.19B $244.26B AMGN
Cheaper on earningsLower P/E, profitable companies only 103.8x 29.1x 27.9x AMGN
Cheaper on forward earningsLower price / next fiscal year consensus EPS 19.1x 29.1x 20.7x BIIB
Faster revenue growthRevenue growth, trailing twelve months +2.3% +61.5% +9.1% ARGX
More profitableNet margin, trailing twelve months 3.4% 32.3% 23.0% ARGX
Better return on capitalReturn on invested capital 1.3% — 14.3% AMGN
Less leveragedLower net debt / EBITDA 4.5x — 2.7x AMGN
Higher dividend yieldTrailing dividend yield — — 2.20% –
Better 1-year returnPrice return, last 12 months +63.6% +6.6% +54.7% BIIB
Better 5-year returnAnnualised price return, 5 years -1.8%/yr +24.2%/yr +16.9%/yr ARGX
Less volatileAnnualised volatility, 1 year 34.2% 36.9% 29.7% AMGN
Higher overall scoreMean of the five percentile scores vs peers 59/100 92/100 66/100 ARGX

Percentile Scorecard

BIIBARGXAMGN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisBIIBARGXAMGN
Valuation 92 #54 of 625 84 #101 of 625 86 #91 of 625
Growth 26 #446 of 602 94 #35 of 602 62 #231 of 602
Profitability 87 #73 of 549 98 #11 of 549 95 #31 of 549
Financial Health 33 #437 of 654 – 22 #510 of 654
Shareholder Returns – – 68 #118 of 367
Overall 59 92 66
  • BIIB ranked among 672 companies in Pharmaceuticals and Biotechnology
  • ARGX ranked among 672 companies in Pharmaceuticals and Biotechnology
  • AMGN ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodBIIBARGXAMGNSPY
1 month +6.7%-8.3%+8.1% +0.9%
3 months +16.6%+1.0%+16.6% +5.9%
6 months +25.6%+14.9%+33.7% +8.5%
Year to date +38.7%+6.0%+38.0% +13.3%
1 year +63.6%+6.6%+54.7% +12.4%
3 years +4.1%+93.9%+72.7% +88.1%
3 years, per year +1.3%+24.7%+20.0% +23.5%
5 years -8.5%+195.3%+118.3% +68.2%
5 years, per year -1.8%+24.2%+16.9% +11.0%
10 years -14.0%—+211.2% +263.4%
10 years, per year -1.5%—+12.0% +13.8%

Risk

MeasureBIIBARGXAMGNSPY
Volatility, 1Y 34.2%36.9%29.7% 12.7%
Downside volatility, 1Y 32.7%34.6%27.9% 12.7%
Beta vs S&P 500, 1Y 0.250.390.46 1.00
Return / volatility, 1Y 1.860.181.84 0.98
Max drawdown, 5Y -64.4%-38.2%-26.7% -25.4%
From 52-week high -3.9%-15.8%0.0% -0.9%
52-week high $253.84$1,058.90$451.83 $779.14
52-week low $147.86$663.93$291.77 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleBIIBARGXAMGN
P/E now vs peer median 103.8xmedian 17.4x 29.1xmedian 17.4x 27.9xmedian 17.4x
P/S now vs peer median 3.5xmedian 9.1x 9.5xmedian 9.1x 6.4xmedian 9.1x
EV/EBITDA now vs peer median 31.7xmedian 17.1x —median 17.1x 17.9xmedian 17.1x
P/FCF now vs peer median 17.4xmedian 19.0x —median 19.0x 24.0xmedian 19.0x
P/B now vs peer median 1.9xmedian 2.2x —median 2.2x 20.9xmedian 2.2x
PEG now vs peer median -2.70median 0.34 0.28median 0.34 10.53median 0.34

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsBIIBARGXAMGN
Revenue $10.30B $5.82B $38.10B
Gross profit $7.62B $5.24B $26.48B
Operating income $445.10M $1.74B $11.43B
Net income $347.50M $1.88B $8.74B
Free cash flow $2.07B – $10.18B
R&D $2.15B $1.80B $7.63B
EPS (diluted) $2.35 $28.43 $16.07
Cash & equivalents $1.30B – $13.99B
Total debt $7.29B – $57.30B
Shares (diluted) 147.80M 66.03M 544.00M
Enterprise value $25.39B $55.19B $199.66B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricBIIBARGXAMGN
P/E 103.8x 29.1x 27.9x
P/FCF 17.4x – 24.0x
P/Operating cash flow 16.1x – 19.6x
P/S 3.5x 9.5x 6.4x
P/B 1.9x – 20.9x
P/Tangible book 6.5x – -27.8x
EV/EBITDA 31.7x – 17.9x
EV/EBIT 94.5x 31.7x 25.2x
EV/Revenue 4.1x 9.5x 7.5x
EV/FCF 20.3x – 28.3x
EV/Operating cash flow 18.7x – 23.0x
PEG (3Y EPS CAGR) -2.70 0.28 10.53

Growth

14 metrics
MetricBIIBARGXAMGN
Revenue growth (1Y) 2.3% 61.5% 9.1%
Revenue CAGR (3Y) 1.0% 80.5% 12.7%
Gross profit growth (1Y) 0.6% 62.2% 17.6%
Gross profit CAGR (3Y) 0.5% 80.0% 10.3%
Operating income growth (1Y) -76.6% 120.6% 39.5%
Operating income CAGR (3Y) -34.8% 85.1% 6.4%
Net income growth (1Y) -78.4% 22.5% 32.1%
Net income CAGR (3Y) -38.1% 115.5% 3.1%
EPS growth (1Y) -78.5% 20.9% 31.4%
EPS CAGR (3Y) -38.5% 104.8% 2.7%
Operating cash flow growth (1Y) -8.4% – 3.9%
Operating cash flow CAGR (3Y) 18.2% – 4.9%
Free cash flow growth (1Y) -10.1% – -4.1%
Free cash flow CAGR (3Y) 24.9% – 1.7%

Profitability

14 metrics
MetricBIIBARGXAMGN
Gross margin 74.0% 90.0% 69.5%
EBITDA margin 12.9% – 42.2%
Operating margin 4.3% 29.9% 30.0%
Pretax margin 4.3% 32.6% 27.0%
Net margin 3.4% 32.3% 23.0%
FCF margin 20.1% – 26.7%
Operating cash flow margin 21.8% – 32.8%
Return on equity 1.8% – 83.8%
Return on assets 1.1% – 9.3%
Return on invested capital 1.3% – 14.3%
Return on capital employed 1.6% – 16.7%
Asset turnover 0.3x – 0.4x
Cash conversion (OCF / net income) 6.5x – 1.4x
Stock comp / revenue 2.9% – 1.3%

Financial Health

11 metrics
MetricBIIBARGXAMGN
Debt / assets 22.7% – 59.9%
Debt / equity 0.4x – 4.9x
Net debt / EBITDA 4.5x – 2.7x
Debt / FCF 3.5x – 5.6x
Liabilities / assets 41.0% – 87.8%
Equity / assets 59.0% – 12.2%
Interest coverage – 10,120x 4.3x
Current ratio 1.9x – 1.4x
Quick ratio 0.9x – 0.9x
Cash ratio 0.3x – 0.5x
Altman Z-score 3.07 – 2.33

Shareholder Returns

7 metrics
MetricBIIBARGXAMGN
Dividend yield – – 2.2%
Net buyback yield – – –
Shareholder yield – – 2.2%
Payout ratio (earnings) – – 60.4%
Payout ratio (FCF) – – 51.9%
Dividend growth (1Y) – – 6.3%
Dividend CAGR (3Y) – – 6.7%

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusBIIBARGXAMGN
Forward P/E 19.1xFY2026 29.1xFY2026 20.7xFY2026
EPS, next fiscal year $12.81FY2026 $30.63FY2026 $21.81FY2026
EPS growth, next FY -16.2%FY2026 +56.5%FY2026 -0.1%FY2026
EPS growth, the year after +36.5% +26.9% +7.2%
Revenue, next fiscal year $9.96BFY2026 $6.08BFY2026 $41.51BFY2026
Revenue growth, next FY +0.7%FY2026 +43.1%FY2026 +12.9%FY2026
Revenue growth, the year after +11.9% +22.9% +2.3%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersBIIBARGXAMGN
Held by institutions 96.4% 46.1% 82.7%
Institutions holding 1,036 504 3,160
Change in shares held, QoQ +6.0% -2.0% +4.5%
Institutions buying 548 264 1,452
Institutions selling 294 160 1,217
Buyers to sellers 1.86 1.65 1.19

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

BIIBARGXAMGN
BIIB 1.00 0.21 0.49
ARGX 0.21 1.00 0.31
AMGN 0.49 0.31 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, BIIB, ARGX and AMGN?

Amgen (AMGN) is the largest by market capitalisation: Biogen (BIIB) $36.08B, Argenx Se (ARGX) $55.19B, Amgen (AMGN) $244.26B.

Which stock is cheaper, BIIB, ARGX and AMGN?

Amgen (AMGN) trades on the lowest price-to-earnings ratio (Biogen (BIIB) 103.8x, Argenx Se (ARGX) 29.1x, Amgen (AMGN) 27.9x). On next year's consensus earnings, Biogen (BIIB) is cheapest (Biogen (BIIB) 19.1x, Argenx Se (ARGX) 29.1x, Amgen (AMGN) 20.7x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Argenx Se (ARGX) grew revenue fastest over the trailing twelve months: Biogen (BIIB) +2.3%, Argenx Se (ARGX) +61.5%, Amgen (AMGN) +9.1%.

Which company is more profitable?

Argenx Se (ARGX) has the highest net margin (Biogen (BIIB) 3.4%, Argenx Se (ARGX) 32.3%, Amgen (AMGN) 23.0%). On return on invested capital, Amgen (AMGN) leads (Biogen (BIIB) 1.3%, Amgen (AMGN) 14.3%).

Which stock has performed better?

Over the past year Biogen (BIIB) returned the most: Biogen (BIIB) +63.6%, Argenx Se (ARGX) +6.6%, Amgen (AMGN) +54.7%. Over five years, Argenx Se (ARGX) compounded fastest (Biogen (BIIB) -1.8%/yr, Argenx Se (ARGX) +24.2%/yr, Amgen (AMGN) +16.9%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Amgen (AMGN) 2.20%. Biogen (BIIB) and Argenx Se (ARGX) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Amgen (AMGN) has been the steadiest (Biogen (BIIB) 34.2%, Argenx Se (ARGX) 36.9%, Amgen (AMGN) 29.7%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, BIIB, ARGX and AMGN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Amgen (AMGN) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.