BEAM vs VCEL vs PGEN Stock Comparison

Beam Therapeutics, Vericel and Precigen Prices as of Oct 26, 2026 Peers: Industry group
BEAM Beam Therapeutics Inc.
$23.79 -2.0% 1M -14.9% 1Y
Market cap
$2.60B
P/E
–
Revenue (TTM)
$156.04M
Div. yield
–
Gene and Cell Therapy Healthcare
1 win
VCEL Vericel Corp
$43.04 +8.4% 1M +18.5% 1Y
Market cap
$2.21B
P/E
91.2x
Revenue (TTM)
$306.30M
Div. yield
–
Gene and Cell Therapy Healthcare
3 wins
PGEN Precigen, Inc.
$6.04 -22.1% 1M +39.5% 1Y
Market cap
$2.19B
P/E
–
Revenue (TTM)
$85.72M
Div. yield
–
Gene and Cell Therapy Healthcare
5 wins

Head to Head

9 decided of 12

Precigen leads on 5 of the 12 questions below (Precigen 5, Vericel 3, Beam Therapeutics 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionBEAMVCELPGENLeader
Larger companyMarket capitalisation $2.60B $2.21B $2.19B BEAM
Cheaper on earningsLower P/E, profitable companies only -30.4x 91.2x -6.5x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 84.4x 35.5x PGEN
Faster revenue growthRevenue growth, trailing twelve months +158.9% +23.0% +1,875.0% PGEN
More profitableNet margin, trailing twelve months -54.7% 7.9% -392.8% VCEL
Better return on capitalReturn on invested capital — — — –
Less leveragedLower net debt / EBITDA 3.0x — -1.6x PGEN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -14.9% +18.5% +39.5% PGEN
Better 5-year returnAnnualised price return, 5 years -23.7%/yr -3.2%/yr +6.1%/yr PGEN
Less volatileAnnualised volatility, 1 year 69.2% 40.9% 78.0% VCEL
Higher overall scoreMean of the five percentile scores vs peers 69/100 81/100 55/100 VCEL

Percentile Scorecard

BEAMVCELPGEN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisBEAMVCELPGEN
Valuation 55 #284 of 626 81 #119 of 626 58 #263 of 626
Growth 77 #138 of 604 94 #37 of 604 48 #312 of 604
Profitability 64 #200 of 555 88 #68 of 555 59 #229 of 555
Financial Health 81 #127 of 658 69 #207 of 658 26 #488 of 658
Shareholder Returns 66 #125 of 368 73 #100 of 368 83 #65 of 368
Overall 69 81 55
  • BEAM ranked among 673 companies in Pharmaceuticals and Biotechnology
  • VCEL ranked among 673 companies in Pharmaceuticals and Biotechnology
  • PGEN ranked among 673 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodBEAMVCELPGENSPY
1 month -2.0%+8.4%-22.1% -0.8%
3 months -5.1%-5.0%+11.4% +3.5%
6 months -18.4%+16.6%+52.5% +7.0%
Year to date -14.2%+19.5%+44.5% +12.2%
1 year -14.9%+18.5%+39.5% +13.0%
3 years +27.8%+31.1%+498.0% +86.3%
3 years, per year +8.5%+9.5%+81.6% +23.1%
5 years -74.1%-14.9%+34.2% +68.6%
5 years, per year -23.7%-3.2%+6.1% +11.0%
10 years —+1,693.3%-76.9% +258.0%
10 years, per year —+33.5%-13.6% +13.6%

Risk

MeasureBEAMVCELPGENSPY
Volatility, 1Y 69.2%40.9%78.0% 12.7%
Downside volatility, 1Y 63.8%40.1%69.4% 12.7%
Beta vs S&P 500, 1Y 2.050.741.42 1.00
Return / volatility, 1Y -0.220.450.51 1.02
Max drawdown, 5Y -85.3%-65.4%-87.8% -25.4%
From 52-week high -37.3%-10.9%-29.4% -1.8%
52-week high $37.92$48.31$8.56 $779.14
52-week low $20.60$29.34$3.10 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleBEAMVCELPGEN
P/E now vs peer median -29.1xmedian 17.1x 90.8xmedian 17.1x -6.4xmedian 17.1x
P/S now vs peer median 15.7xmedian 8.8x 7.2xmedian 8.8x 25.2xmedian 8.8x
EV/EBITDA now vs peer median -3.9xmedian 17.1x 65.0xmedian 17.1x -64.7xmedian 17.1x
P/FCF now vs peer median -6.6xmedian 18.0x 35.7xmedian 18.0x -18.8xmedian 18.0x
P/B now vs peer median 2.3xmedian 2.1x 6.0xmedian 2.1x 49.6xmedian 2.1x
PEG now vs peer median -0.69median 0.31 1.67median 0.31 0.05median 0.31

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsBEAMVCELPGEN
Revenue $156.04M $306.30M $85.72M
Gross profit – $228.38M $77.72M
Operating income -$378.02M $18.24M -$39.50M
Net income -$86.52M $24.22M -$157.71M
Free cash flow -$372.77M $61.66M -$115.22M
R&D $408.66M $29.17M $32.29M
EPS (diluted) $-0.82 $0.46 $-0.81
Cash & equivalents $219.83M $125.40M $16.33M
Total debt $100.26M – $93.88M
Shares (diluted) 104.33M 52.31M 413.69M
Enterprise value -$2.08B $1.63B $1.88B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricBEAMVCELPGEN
P/E -29.1x 90.8x -6.4x
P/FCF -6.6x 35.7x -18.8x
P/Operating cash flow -6.8x 31.6x -18.9x
P/S 15.7x 7.2x 25.2x
P/B 2.3x 6.0x 49.6x
P/Tangible book 2.3x 6.0x 52.7x
EV/EBITDA -3.9x 65.0x -64.7x
EV/EBIT -3.7x 111.9x -56.2x
EV/Revenue 9.0x 6.7x 25.9x
EV/FCF -3.8x 33.1x -19.3x
EV/Operating cash flow -3.9x 29.3x -19.4x
PEG (3Y EPS CAGR) -0.69 1.67 0.05

Growth

14 metrics
MetricBEAMVCELPGEN
Revenue growth (1Y) 158.9% 23.0% 1,875%
Revenue CAGR (3Y) 24.9% 19.8% 57.1%
Gross profit growth (1Y) – 24.8% 259,173%
Gross profit CAGR (3Y) – 23.9% 69.2%
Operating income growth (1Y) 15.2% 1,428% 62.1%
Operating income CAGR (3Y) 0.3% 47.8% 18.9%
Net income growth (1Y) 78.2% 240.8% -26.7%
Net income CAGR (3Y) 35.8% 56.6% -108.9%
EPS growth (1Y) 79.0% 228.1% -93.8%
EPS CAGR (3Y) 42.4% 54.3% -123.2%
Operating cash flow growth (1Y) -4.2% 47.5% -72.3%
Operating cash flow CAGR (3Y) -2.0% 33.7% -15.9%
Free cash flow growth (1Y) -4.8% 842.9% -65.1%
Free cash flow CAGR (3Y) 0.7% 43.2% -15.3%

Profitability

14 metrics
MetricBEAMVCELPGEN
Gross margin – 74.6% 90.7%
EBITDA margin -228.0% 10.2% -40.0%
Operating margin -242.3% 6.0% -46.1%
Pretax margin -54.4% 8.2% -184.0%
Net margin -54.7% 7.9% -392.8%
FCF margin -238.9% 20.1% -134.4%
Operating cash flow margin -230.3% 22.7% -133.2%
Return on equity -7.6% 6.9% -494.3%
Return on assets -5.9% 5.1% -102.1%
Return on invested capital – – –
Return on capital employed -27.9% 4.1% -31.6%
Asset turnover 0.1x 0.6x 0.6x
Cash conversion (OCF / net income) 4.2x 2.9x 0.7x
Stock comp / revenue 52.2% 12.2% 15.3%

Financial Health

11 metrics
MetricBEAMVCELPGEN
Debt / assets 7.2% – 55.1%
Debt / equity 0.1x – 2.2x
Net debt / EBITDA 3.0x – -1.6x
Debt / FCF -0.3x – -0.8x
Liabilities / assets 23.0% 26.4% 74.4%
Equity / assets 77.0% 73.6% 25.6%
Interest coverage – 28.5x -4.1x
Current ratio 14.6x 5.0x 4.6x
Quick ratio 14.3x 4.5x 3.8x
Cash ratio 14.3x 3.1x 1.3x
Altman Z-score 2.87 10.12 -8.43

Shareholder Returns

7 metrics
MetricBEAMVCELPGEN
Dividend yield – – –
Net buyback yield -0.6% -0.3% -0.1%
Shareholder yield -0.6% -0.3% -0.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusBEAMVCELPGEN
Forward P/E – 84.4xFY2026 35.5xFY2026
EPS, next fiscal year $-4.22FY2026 $0.51FY2026 $0.17FY2026
EPS growth, next FY – +59.4%FY2026 –
EPS growth, the year after – +74.5% +288.2%
Revenue, next fiscal year $49.46MFY2026 $324.56MFY2026 $249.17MFY2026
Revenue growth, next FY -64.6%FY2026 +17.5%FY2026 +2,474.1%FY2026
Revenue growth, the year after +23.6% +16.1% +82.3%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersBEAMVCELPGEN
Held by institutions 100.0% 100.0% 39.2%
Institutions holding 277 317 210
Change in shares held, QoQ +1.0% +0.4% +4.9%
Institutions buying 154 187 123
Institutions selling 75 98 46
Buyers to sellers 2.05 1.91 2.67

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

BEAMVCELPGEN
BEAM 1.00 0.25 0.26
VCEL 0.25 1.00 0.17
PGEN 0.26 0.17 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, BEAM, VCEL and PGEN?

Beam Therapeutics (BEAM) is the largest by market capitalisation: Beam Therapeutics (BEAM) $2.60B, Vericel (VCEL) $2.21B, Precigen (PGEN) $2.19B.

Which company is growing faster?

Precigen (PGEN) grew revenue fastest over the trailing twelve months: Beam Therapeutics (BEAM) +158.9%, Vericel (VCEL) +23.0%, Precigen (PGEN) +1,875.0%.

Which company is more profitable?

Vericel (VCEL) has the highest net margin (Beam Therapeutics (BEAM) -54.7%, Vericel (VCEL) 7.9%, Precigen (PGEN) -392.8%).

Which stock has performed better?

Over the past year Precigen (PGEN) returned the most: Beam Therapeutics (BEAM) -14.9%, Vericel (VCEL) +18.5%, Precigen (PGEN) +39.5%. Over five years, Precigen (PGEN) compounded fastest (Beam Therapeutics (BEAM) -23.7%/yr, Vericel (VCEL) -3.2%/yr, Precigen (PGEN) +6.1%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Vericel (VCEL) has been the steadiest (Beam Therapeutics (BEAM) 69.2%, Vericel (VCEL) 40.9%, Precigen (PGEN) 78.0%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, BEAM, VCEL and PGEN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Precigen (PGEN) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.