AUPH vs TAK vs AZN Stock Comparison

Aurinia Pharmaceuticals, Takeda Pharmaceutical and Astrazeneca Prices as of Oct 28, 2026 Peers: Industry group
AZN Astrazeneca Plc
$169.54 +1.9% 1M +2.6% 1Y
Market cap
$262.79B
P/E
25.2x
Revenue (TTM)
$58.67B
Div. yield
1.41%
Pharmaceuticals Healthcare
4 wins

Head to Head

12 decided of 12

Astrazeneca leads on 4 of the 12 questions below (Astrazeneca 4, Aurinia Pharmaceuticals 4, Takeda Pharmaceutical 4). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionAUPHTAKAZNLeader
Larger companyMarket capitalisation $2.31B $64.13B $262.79B AZN
Cheaper on earningsLower P/E, profitable companies only 7.2x 110.5x 25.2x AUPH
Cheaper on forward earningsLower price / next fiscal year consensus EPS 18.1x 50.4x 17.0x AZN
Faster revenue growthRevenue growth, trailing twelve months +19.8% +0.7% +9.4% AUPH
More profitableNet margin, trailing twelve months 100.8% 1.2% 17.8% AUPH
Better return on capitalReturn on invested capital — 3.5% 23.3% AZN
Less leveragedLower net debt / EBITDA — 3.5x 1.4x AZN
Higher dividend yieldTrailing dividend yield — 1.54% 1.41% TAK
Better 1-year returnPrice return, last 12 months +37.5% +42.9% +2.6% TAK
Better 5-year returnAnnualised price return, 5 years -12.1%/yr +7.5%/yr +6.3%/yr TAK
Less volatileAnnualised volatility, 1 year 37.2% 21.5% 27.3% TAK
Higher overall scoreMean of the five percentile scores vs peers 90/100 62/100 71/100 AUPH

Percentile Scorecard

AUPHTAKAZN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisAUPHTAKAZN
Valuation 93 #45 of 625 98 #16 of 625 85 #92 of 625
Growth 96 #26 of 602 21 #476 of 602 70 #183 of 602
Profitability 97 #17 of 549 85 #82 of 549 94 #34 of 549
Financial Health 74 #172 of 654 34 #430 of 654 36 #418 of 654
Shareholder Returns 92 #31 of 367 74 #98 of 367 70 #112 of 367
Overall 90 62 71
  • AUPH ranked among 672 companies in Pharmaceuticals and Biotechnology
  • TAK ranked among 672 companies in Pharmaceuticals and Biotechnology
  • AZN ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodAUPHTAKAZNSPY
1 month +5.1%+6.6%+1.9% +0.9%
3 months +14.4%+13.5%-2.2% +5.9%
6 months +13.6%+23.6%-8.5% +8.5%
Year to date +8.8%+29.2%-7.8% +13.3%
1 year +37.5%+42.9%+2.6% +12.4%
3 years +141.4%+49.6%+37.0% +88.1%
3 years, per year +34.2%+14.4%+11.1% +23.5%
5 years -47.5%+43.7%+35.9% +68.2%
5 years, per year -12.1%+7.5%+6.3% +11.0%
10 years +437.5%-12.4%+196.4% +263.4%
10 years, per year +18.3%-1.3%+11.5% +13.8%

Risk

MeasureAUPHTAKAZNSPY
Volatility, 1Y 37.2%21.5%27.3% 12.7%
Downside volatility, 1Y 34.0%20.2%27.1% 12.7%
Beta vs S&P 500, 1Y 0.540.110.21 1.00
Return / volatility, 1Y 1.011.990.10 0.98
Max drawdown, 5Y -87.6%-26.4%-27.9% -25.4%
From 52-week high -6.8%-1.4%-19.1% -0.9%
52-week high $18.62$20.43$209.48 $779.14
52-week low $12.12$13.23$155.60 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleAUPHTAKAZN
P/E now vs peer median 7.2xmedian 17.4x 110.5xmedian 17.4x 25.2xmedian 17.4x
P/S now vs peer median 7.4xmedian 9.1x 1.4xmedian 9.1x 4.5xmedian 9.1x
EV/EBITDA now vs peer median 11.0xmedian 17.1x 12.3xmedian 17.1x 14.3xmedian 17.1x
P/FCF now vs peer median 13.2xmedian 19.0x 12.3xmedian 19.0x 24.6xmedian 19.0x
P/B now vs peer median 3.8xmedian 2.2x 1.4xmedian 2.2x 5.2xmedian 2.2x
PEG now vs peer median 0.08median 0.34 -2.72median 0.34 1.31median 0.34

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsAUPHTAKAZN
Revenue $311.51M $46.49B $58.67B
Gross profit $281.47M $30.58B $50.25B
Operating income $150.75M $2.71B $13.97B
Net income $314.11M -$1.04B $10.45B
Free cash flow $175.07M $5.20B $10.67B
R&D $39.85M $4.53B $15.07B
EPS (diluted) $2.35 $0.18 $6.69
Cash & equivalents $179.83M $2.85B $4.90B
Total debt – $126.30B $32.35B
Shares (diluted) 133.53M 3.15B 1.56B
Enterprise value $735.55M $40.50B $236.55B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricAUPHTAKAZN
P/E 7.2x 110.5x 25.2x
P/FCF 13.2x 12.3x 24.6x
P/Operating cash flow 13.2x 10.2x 19.2x
P/S 7.4x 1.4x 4.5x
P/B 3.8x 1.4x 5.2x
P/Tangible book 3.8x 2.5x 20.8x
EV/EBITDA 11.0x 12.3x 14.3x
EV/EBIT 12.4x 33.0x 20.8x
EV/Revenue 6.0x 1.9x 4.9x
EV/FCF 10.6x 17.2x 27.2x
EV/Operating cash flow 10.6x 14.3x 21.2x
PEG (3Y EPS CAGR) 0.08 -2.72 1.31

Growth

14 metrics
MetricAUPHTAKAZN
Revenue growth (1Y) 19.8% 0.7% 9.4%
Revenue CAGR (3Y) 24.8% 14.8% 10.6%
Gross profit growth (1Y) 20.9% -0.8% 9.3%
Gross profit CAGR (3Y) 22.2% -0.2% 13.1%
Operating income growth (1Y) 189.8% -43.4% 23.4%
Operating income CAGR (3Y) 56.2% -14.3% 23.9%
Net income growth (1Y) 418.0% -209.1% 25.9%
Net income CAGR (3Y) 84.9% -35.3% 19.2%
EPS growth (1Y) 433.5% -75.7% 26.0%
EPS CAGR (3Y) 87.7% -40.6% 19.2%
Operating cash flow growth (1Y) 89.1% -14.8% 2.3%
Operating cash flow CAGR (3Y) 86.1% -4.4% 13.7%
Free cash flow growth (1Y) 89.4% -13.3% -4.5%
Free cash flow CAGR (3Y) 85.3% -5.2% 8.5%

Profitability

14 metrics
MetricAUPHTAKAZN
Gross margin 90.4% 65.8% 85.6%
EBITDA margin 54.6% 15.6% 34.6%
Operating margin 48.4% 5.8% 23.8%
Pretax margin 51.5% 2.6% 21.5%
Net margin 100.8% 1.2% 17.8%
FCF margin 56.2% 11.2% 18.2%
Operating cash flow margin 56.3% 13.5% 23.3%
Return on equity 53.1% 1.2% 21.4%
Return on assets 41.4% 0.6% 9.1%
Return on invested capital – 3.5% 23.3%
Return on capital employed 22.9% 3.0% 16.8%
Asset turnover 0.4x 0.5x 0.5x
Cash conversion (OCF / net income) 0.6x -6.0x 1.3x
Stock comp / revenue 4.7% 1.0% –

Financial Health

11 metrics
MetricAUPHTAKAZN
Debt / assets – 32.0% 27.9%
Debt / equity – 0.7x 0.6x
Net debt / EBITDA – 3.5x 1.4x
Debt / FCF – 6.0x 3.0x
Liabilities / assets 22.4% 51.7% 56.5%
Equity / assets 77.6% 48.3% 43.5%
Interest coverage 36.7x 0.8x 15.9x
Current ratio 5.4x 3.2x 0.9x
Quick ratio 4.8x 1.9x 0.7x
Cash ratio 4.4x 0.9x 0.2x
Altman Z-score 8.47 1.57 3.43

Shareholder Returns

7 metrics
MetricAUPHTAKAZN
Dividend yield – 1.5% 1.4%
Net buyback yield 0.9% 1.0% 0.0%
Shareholder yield 0.9% 2.6% 1.4%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusAUPHTAKAZN
Forward P/E 18.1xFY2026 50.4xFY2026 17.0xFY2026
EPS, next fiscal year $0.96FY2026 $0.40FY2026 $10.00FY2026
EPS growth, next FY -53.6%FY2026 +5.3%FY2026 +9.2%FY2026
EPS growth, the year after +14.6% +62.5% +6.1%
Revenue, next fiscal year $348.13MFY2026 $28.27BFY2026 $59.02BFY2026
Revenue growth, next FY +23.0%FY2026 -0.8%FY2026 +0.5%FY2026
Revenue growth, the year after +6.9% +11.9% +8.0%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersAUPHTAKAZN
Held by institutions 58.7% 3.3% 52.1%
Institutions holding 280 378 1,496
Change in shares held, QoQ +5.4% +6.2% +7.8%
Institutions buying 156 212 808
Institutions selling 78 98 468
Buyers to sellers 2.00 2.16 1.73

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

AUPHTAKAZN
AUPH 1.00 0.18 0.23
TAK 0.18 1.00 0.52
AZN 0.23 0.52 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, AUPH, TAK and AZN?

Astrazeneca (AZN) is the largest by market capitalisation: Aurinia Pharmaceuticals (AUPH) $2.31B, Takeda Pharmaceutical (TAK) $64.13B, Astrazeneca (AZN) $262.79B.

Which stock is cheaper, AUPH, TAK and AZN?

Aurinia Pharmaceuticals (AUPH) trades on the lowest price-to-earnings ratio (Aurinia Pharmaceuticals (AUPH) 7.2x, Takeda Pharmaceutical (TAK) 110.5x, Astrazeneca (AZN) 25.2x). On next year's consensus earnings, Astrazeneca (AZN) is cheapest (Aurinia Pharmaceuticals (AUPH) 18.1x, Takeda Pharmaceutical (TAK) 50.4x, Astrazeneca (AZN) 17.0x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Aurinia Pharmaceuticals (AUPH) grew revenue fastest over the trailing twelve months: Aurinia Pharmaceuticals (AUPH) +19.8%, Takeda Pharmaceutical (TAK) +0.7%, Astrazeneca (AZN) +9.4%.

Which company is more profitable?

Aurinia Pharmaceuticals (AUPH) has the highest net margin (Aurinia Pharmaceuticals (AUPH) 100.8%, Takeda Pharmaceutical (TAK) 1.2%, Astrazeneca (AZN) 17.8%). On return on invested capital, Astrazeneca (AZN) leads (Takeda Pharmaceutical (TAK) 3.5%, Astrazeneca (AZN) 23.3%).

Which stock has performed better?

Over the past year Takeda Pharmaceutical (TAK) returned the most: Aurinia Pharmaceuticals (AUPH) +37.5%, Takeda Pharmaceutical (TAK) +42.9%, Astrazeneca (AZN) +2.6%. Over five years, Takeda Pharmaceutical (TAK) compounded fastest (Aurinia Pharmaceuticals (AUPH) -12.1%/yr, Takeda Pharmaceutical (TAK) +7.5%/yr, Astrazeneca (AZN) +6.3%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Takeda Pharmaceutical (TAK) has the highest dividend yield: Takeda Pharmaceutical (TAK) 1.54%, Astrazeneca (AZN) 1.41%. Aurinia Pharmaceuticals (AUPH) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Takeda Pharmaceutical (TAK) has been the steadiest (Aurinia Pharmaceuticals (AUPH) 37.2%, Takeda Pharmaceutical (TAK) 21.5%, Astrazeneca (AZN) 27.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, AUPH, TAK and AZN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Astrazeneca (AZN) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.