AUPH vs AZN vs NUVB Stock Comparison

Aurinia Pharmaceuticals, Astrazeneca and Nuvation Bio Prices as of Oct 27, 2026 Peers: Industry group
AZN Astrazeneca Plc
$170.02 +2.1% 1M +1.1% 1Y
Market cap
$264.00B
P/E
25.3x
Revenue (TTM)
$58.67B
Div. yield
–
Pharmaceuticals Healthcare
5 wins
NUVB Nuvation Bio Inc.
$4.54 -20.6% 1M -9.9% 1Y
Market cap
$1.59B
P/E
–
Revenue (TTM)
$169.90M
Div. yield
–
Pharmaceuticals Healthcare
1 win

Head to Head

10 decided of 12

Astrazeneca leads on 5 of the 12 questions below (Astrazeneca 5, Aurinia Pharmaceuticals 4, Nuvation Bio 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionAUPHAZNNUVBLeader
Larger companyMarket capitalisation $2.24B $264.00B $1.59B AZN
Cheaper on earningsLower P/E, profitable companies only 7.1x 25.3x -10.6x AUPH
Cheaper on forward earningsLower price / next fiscal year consensus EPS 18.0x 17.0x — AZN
Faster revenue growthRevenue growth, trailing twelve months +19.8% +9.4% +1,083.6% NUVB
More profitableNet margin, trailing twelve months 100.8% 17.8% -88.2% AUPH
Better return on capitalReturn on invested capital — 23.3% — –
Less leveragedLower net debt / EBITDA — 1.4x 4.9x AZN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +40.4% +1.1% -9.9% AUPH
Better 5-year returnAnnualised price return, 5 years -10.5%/yr +6.5%/yr -13.7%/yr AZN
Less volatileAnnualised volatility, 1 year 37.3% 27.4% 79.1% AZN
Higher overall scoreMean of the five percentile scores vs peers 90/100 71/100 63/100 AUPH

Percentile Scorecard

AUPHAZNNUVB

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisAUPHAZNNUVB
Valuation 93 #46 of 625 86 #91 of 625 59 #256 of 625
Growth 96 #25 of 602 70 #183 of 602 61 #236 of 602
Profitability 97 #17 of 551 94 #34 of 551 65 #192 of 551
Financial Health 74 #174 of 656 36 #420 of 656 67 #218 of 656
Shareholder Returns 92 #31 of 365 70 #111 of 365 64 #131 of 365
Overall 90 71 63
  • AUPH ranked among 672 companies in Pharmaceuticals and Biotechnology
  • AZN ranked among 672 companies in Pharmaceuticals and Biotechnology
  • NUVB ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodAUPHAZNNUVBSPY
1 month +4.9%+2.1%-20.6% -0.2%
3 months +15.3%-1.4%-32.2% +3.9%
6 months +7.5%-8.9%-0.4% +8.2%
Year to date +8.2%-7.5%-49.3% +12.9%
1 year +40.4%+1.1%-9.9% +12.3%
3 years +139.9%+37.4%+345.1% +87.4%
3 years, per year +33.9%+11.2%+64.6% +23.3%
5 years -42.4%+36.7%-52.2% +67.9%
5 years, per year -10.5%+6.5%-13.7% +10.9%
10 years +444.2%+197.9%— +261.1%
10 years, per year +18.5%+11.5%— +13.7%

Risk

MeasureAUPHAZNNUVBSPY
Volatility, 1Y 37.3%27.4%79.1% 12.7%
Downside volatility, 1Y 34.0%27.2%76.7% 12.7%
Beta vs S&P 500, 1Y 0.540.211.64 1.00
Return / volatility, 1Y 1.080.04-0.13 0.97
Max drawdown, 5Y -87.6%-27.9%-90.4% -25.4%
From 52-week high -7.4%-18.8%-52.4% -1.2%
52-week high $18.62$209.48$9.54 $779.14
52-week low $12.12$155.60$4.05 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleAUPHAZNNUVB
P/E now vs peer median 7.1xmedian 17.2x 25.2xmedian 17.2x -10.6xmedian 17.2x
P/S now vs peer median 7.4xmedian 9.0x 4.5xmedian 9.0x 9.3xmedian 9.0x
EV/EBITDA now vs peer median 10.9xmedian 16.3x 14.3xmedian 16.3x -6.8xmedian 16.3x
P/FCF now vs peer median 13.1xmedian 18.7x 24.7xmedian 18.7x -12.2xmedian 18.7x
P/B now vs peer median 3.7xmedian 2.2x 5.2xmedian 2.2x 6.2xmedian 2.2x
PEG now vs peer median 0.08median 0.33 1.31median 0.33 8.07median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsAUPHAZNNUVB
Revenue $311.51M $58.67B $169.90M
Gross profit $281.47M $50.25B –
Operating income $150.75M $13.97B -$137.63M
Net income $314.11M $10.45B -$149.83M
Free cash flow $175.07M $10.67B -$128.93M
R&D $39.85M $15.07B $128.85M
EPS (diluted) $2.35 $6.69 $-0.43
Cash & equivalents $179.83M $4.90B $258.60M
Total debt – $32.35B $5.89M
Shares (diluted) 133.53M 1.56B 348.77M
Enterprise value $664.38M $237.68B -$686.04M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricAUPHAZNNUVB
P/E 7.1x 25.2x -10.6x
P/FCF 13.1x 24.7x -12.2x
P/Operating cash flow 13.1x 19.2x -13.1x
P/S 7.4x 4.5x 9.3x
P/B 3.7x 5.2x 6.2x
P/Tangible book 3.7x 20.8x 6.5x
EV/EBITDA 10.9x 14.3x -6.8x
EV/EBIT 12.3x 20.8x -6.7x
EV/Revenue 5.9x 5.0x 5.4x
EV/FCF 10.6x 27.3x -7.1x
EV/Operating cash flow 10.6x 21.2x -7.6x
PEG (3Y EPS CAGR) 0.08 1.31 8.07

Growth

14 metrics
MetricAUPHAZNNUVB
Revenue growth (1Y) 19.8% 9.4% 1,084%
Revenue CAGR (3Y) 24.8% 10.6% –
Gross profit growth (1Y) 20.9% 9.3% –
Gross profit CAGR (3Y) 22.2% 13.1% –
Operating income growth (1Y) 189.8% 23.4% 38.7%
Operating income CAGR (3Y) 56.2% 23.9% -9.0%
Net income growth (1Y) 418.0% 25.9% 26.2%
Net income CAGR (3Y) 84.9% 19.2% -18.3%
EPS growth (1Y) 433.5% 26.0% 27.9%
EPS CAGR (3Y) 87.7% 19.2% -1.3%
Operating cash flow growth (1Y) 89.1% 2.3% 28.3%
Operating cash flow CAGR (3Y) 86.1% 13.7% -14.1%
Free cash flow growth (1Y) 89.4% -4.5% 23.5%
Free cash flow CAGR (3Y) 85.3% 8.5% -16.6%

Profitability

14 metrics
MetricAUPHAZNNUVB
Gross margin 90.4% 85.6% –
EBITDA margin 54.6% 34.6% -79.0%
Operating margin 48.4% 23.8% -81.0%
Pretax margin 51.5% 21.5% -88.2%
Net margin 100.8% 17.8% -88.2%
FCF margin 56.2% 18.2% -75.9%
Operating cash flow margin 56.3% 23.3% -70.9%
Return on equity 53.1% 21.4% -52.3%
Return on assets 41.4% 9.1% -22.1%
Return on invested capital – 23.3% –
Return on capital employed 22.9% 16.8% -23.3%
Asset turnover 0.4x 0.5x 0.3x
Cash conversion (OCF / net income) 0.6x 1.3x 0.8x
Stock comp / revenue 4.7% – 20.9%

Financial Health

11 metrics
MetricAUPHAZNNUVB
Debt / assets – 27.9% 0.8%
Debt / equity – 0.6x 0.0x
Net debt / EBITDA – 1.4x 4.9x
Debt / FCF – 3.0x 0.0x
Liabilities / assets 22.4% 56.5% 65.9%
Equity / assets 77.6% 43.5% 34.1%
Interest coverage 36.7x 15.9x -5.2x
Current ratio 5.4x 0.9x 8.4x
Quick ratio 4.8x 0.7x 7.9x
Cash ratio 4.4x 0.2x 7.6x
Altman Z-score 8.42 3.43 0.37

Shareholder Returns

7 metrics
MetricAUPHAZNNUVB
Dividend yield – 1.4% –
Net buyback yield 0.9% 0.0% -0.7%
Shareholder yield 0.9% 1.4% -0.7%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusAUPHAZNNUVB
Forward P/E 18.0xFY2026 17.0xFY2026 –
EPS, next fiscal year $0.96FY2026 $10.00FY2026 $-0.38FY2026
EPS growth, next FY -53.6%FY2026 +9.2%FY2026 –
EPS growth, the year after +14.6% +6.1% –
Revenue, next fiscal year $348.13MFY2026 $59.02BFY2026 $187.51MFY2026
Revenue growth, next FY +23.0%FY2026 +0.5%FY2026 +198.1%FY2026
Revenue growth, the year after +6.9% +8.0% +52.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersAUPHAZNNUVB
Held by institutions 58.7% 52.1% 66.6%
Institutions holding 280 1,496 238
Change in shares held, QoQ +5.4% +7.8% +5.7%
Institutions buying 156 808 148
Institutions selling 78 468 50
Buyers to sellers 2.00 1.73 2.96

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

AUPHAZNNUVB
AUPH 1.00 0.23 0.19
AZN 0.23 1.00 0.15
NUVB 0.19 0.15 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, AUPH, AZN and NUVB?

Astrazeneca (AZN) is the largest by market capitalisation: Aurinia Pharmaceuticals (AUPH) $2.24B, Astrazeneca (AZN) $264.00B, Nuvation Bio (NUVB) $1.59B.

Which stock is cheaper, AUPH, AZN and NUVB?

Aurinia Pharmaceuticals (AUPH) trades on the lowest price-to-earnings ratio (Aurinia Pharmaceuticals (AUPH) 7.1x, Astrazeneca (AZN) 25.3x, Nuvation Bio (NUVB) -10.6x). On next year's consensus earnings, Astrazeneca (AZN) is cheapest (Aurinia Pharmaceuticals (AUPH) 18.0x, Astrazeneca (AZN) 17.0x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Nuvation Bio (NUVB) grew revenue fastest over the trailing twelve months: Aurinia Pharmaceuticals (AUPH) +19.8%, Astrazeneca (AZN) +9.4%, Nuvation Bio (NUVB) +1,083.6%.

Which company is more profitable?

Aurinia Pharmaceuticals (AUPH) has the highest net margin (Aurinia Pharmaceuticals (AUPH) 100.8%, Astrazeneca (AZN) 17.8%, Nuvation Bio (NUVB) -88.2%).

Which stock has performed better?

Over the past year Aurinia Pharmaceuticals (AUPH) returned the most: Aurinia Pharmaceuticals (AUPH) +40.4%, Astrazeneca (AZN) +1.1%, Nuvation Bio (NUVB) -9.9%. Over five years, Astrazeneca (AZN) compounded fastest (Aurinia Pharmaceuticals (AUPH) -10.5%/yr, Astrazeneca (AZN) +6.5%/yr, Nuvation Bio (NUVB) -13.7%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Astrazeneca (AZN) has been the steadiest (Aurinia Pharmaceuticals (AUPH) 37.3%, Astrazeneca (AZN) 27.4%, Nuvation Bio (NUVB) 79.1%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, AUPH, AZN and NUVB?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Astrazeneca (AZN) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.