ARQT vs AMGN vs ARGX Stock Comparison

Arcutis Biotherapeutics, Amgen and Argenx Se Prices as of Oct 27, 2026 Peers: Industry group
AMGN Amgen Inc
$447.95 +8.0% 1M +53.9% 1Y
Market cap
$242.16B
P/E
27.7x
Revenue (TTM)
$38.10B
Div. yield
2.22%
Biotechnology Healthcare
5 wins
ARGX Argenx Se
$882.48 -8.0% 1M +6.3% 1Y
Market cap
$54.61B
P/E
28.8x
Revenue (TTM)
$5.82B
Div. yield
–
Biotechnology Healthcare
3 wins

Head to Head

10 decided of 12

Amgen leads on 5 of the 12 questions below (Amgen 5, Argenx Se 3, Arcutis Biotherapeutics 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionARQTAMGNARGXLeader
Larger companyMarket capitalisation $3.98B $242.16B $54.61B AMGN
Cheaper on earningsLower P/E, profitable companies only 145.0x 27.7x 28.8x AMGN
Cheaper on forward earningsLower price / next fiscal year consensus EPS 63.4x 20.5x 28.8x AMGN
Faster revenue growthRevenue growth, trailing twelve months +76.1% +9.1% +61.5% ARQT
More profitableNet margin, trailing twelve months 6.1% 23.0% 32.3% ARGX
Better return on capitalReturn on invested capital 10.6% 14.3% — AMGN
Less leveragedLower net debt / EBITDA — 2.7x — –
Higher dividend yieldTrailing dividend yield — 2.22% — –
Better 1-year returnPrice return, last 12 months +61.3% +53.9% +6.3% ARQT
Better 5-year returnAnnualised price return, 5 years +7.9%/yr +16.7%/yr +25.8%/yr ARGX
Less volatileAnnualised volatility, 1 year 56.7% 29.6% 36.9% AMGN
Higher overall scoreMean of the five percentile scores vs peers 76/100 66/100 92/100 ARGX

Percentile Scorecard

ARQTAMGNARGX

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisARQTAMGNARGX
Valuation 70 #187 of 625 86 #90 of 625 84 #99 of 625
Growth 96 #28 of 602 62 #231 of 602 94 #35 of 602
Profitability 89 #61 of 551 95 #31 of 551 98 #11 of 551
Financial Health 47 #348 of 656 22 #510 of 656 –
Shareholder Returns 77 #85 of 365 68 #117 of 365 –
Overall 76 66 92
  • ARQT ranked among 672 companies in Pharmaceuticals and Biotechnology
  • AMGN ranked among 672 companies in Pharmaceuticals and Biotechnology
  • ARGX ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodARQTAMGNARGXSPY
1 month +17.7%+8.0%-8.0% -0.2%
3 months +11.5%+14.0%+1.2% +3.9%
6 months +36.0%+31.9%+13.9% +8.2%
Year to date +9.1%+36.9%+4.9% +12.9%
1 year +61.3%+53.9%+6.3% +12.3%
3 years +1,256.7%+71.3%+91.9% +87.4%
3 years, per year +138.6%+19.7%+24.3% +23.3%
5 years +46.4%+116.2%+214.2% +67.9%
5 years, per year +7.9%+16.7%+25.8% +10.9%
10 years —+179.0%— +261.1%
10 years, per year —+10.8%— +13.7%

Risk

MeasureARQTAMGNARGXSPY
Volatility, 1Y 56.7%29.6%36.9% 12.7%
Downside volatility, 1Y 49.3%27.9%34.6% 12.7%
Beta vs S&P 500, 1Y 1.080.460.39 1.00
Return / volatility, 1Y 1.081.820.17 0.97
Max drawdown, 5Y -93.2%-26.7%-38.2% -25.4%
From 52-week high -3.5%0.0%-16.7% -1.2%
52-week high $32.82$447.95$1,058.90 $779.14
52-week low $19.50$291.16$663.93 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleARQTAMGNARGX
P/E now vs peer median 145.0xmedian 17.2x 27.7xmedian 17.2x 28.8xmedian 17.2x
P/S now vs peer median 8.6xmedian 9.0x 6.4xmedian 9.0x 9.4xmedian 9.0x
EV/EBITDA now vs peer median —median 16.3x 17.7xmedian 16.3x —median 16.3x
P/FCF now vs peer median 101.6xmedian 18.7x 23.8xmedian 18.7x —median 18.7x
P/B now vs peer median 18.0xmedian 2.2x 20.7xmedian 2.2x —median 2.2x
PEG now vs peer median 5.41median 0.33 10.44median 0.33 0.27median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsARQTAMGNARGX
Revenue $463.98M $38.10B $5.82B
Gross profit $422.89M $26.48B $5.24B
Operating income $34.25M $11.43B $1.74B
Net income $28.52M $8.74B $1.88B
Free cash flow $39.15M $10.18B –
R&D $91.04M $7.63B $1.80B
EPS (diluted) $0.21 $16.07 $28.43
Cash & equivalents – $13.99B –
Total debt $108.90M $57.30B –
Shares (diluted) 135.90M 544.00M 66.03M
Enterprise value $3.26B $197.56B $54.61B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricARQTAMGNARGX
P/E 145.0x 27.7x 28.8x
P/FCF 101.6x 23.8x –
P/Operating cash flow 101.2x 19.4x –
P/S 8.6x 6.4x 9.4x
P/B 18.0x 20.7x –
P/Tangible book 19.2x -27.5x –
EV/EBITDA – 17.7x –
EV/EBIT 113.4x 25.0x 31.4x
EV/Revenue 8.4x 7.5x 9.4x
EV/FCF 99.2x 28.1x –
EV/Operating cash flow 98.8x 22.9x –
PEG (3Y EPS CAGR) 5.41 10.44 0.27

Growth

14 metrics
MetricARQTAMGNARGX
Revenue growth (1Y) 76.1% 9.1% 61.5%
Revenue CAGR (3Y) 241.4% 12.7% 80.5%
Gross profit growth (1Y) 80.2% 17.6% 62.2%
Gross profit CAGR (3Y) 256.4% 10.3% 80.0%
Operating income growth (1Y) 139.9% 39.5% 120.6%
Operating income CAGR (3Y) 28.2% 6.4% 85.1%
Net income growth (1Y) 130.6% 32.1% 22.5%
Net income CAGR (3Y) 27.8% 3.1% 115.5%
EPS growth (1Y) 128.6% 31.4% 20.9%
EPS CAGR (3Y) 26.8% 2.7% 104.8%
Operating cash flow growth (1Y) 160.0% 3.9% –
Operating cash flow CAGR (3Y) 28.8% 4.9% –
Free cash flow growth (1Y) 159.0% -4.1% –
Free cash flow CAGR (3Y) 28.8% 1.7% –

Profitability

14 metrics
MetricARQTAMGNARGX
Gross margin 91.1% 69.5% 90.0%
EBITDA margin – 42.2% –
Operating margin 7.4% 30.0% 29.9%
Pretax margin 6.3% 27.0% 32.6%
Net margin 6.1% 23.0% 32.3%
FCF margin 8.4% 26.7% –
Operating cash flow margin 8.5% 32.8% –
Return on equity 13.9% 83.8% –
Return on assets 6.0% 9.3% –
Return on invested capital 10.6% 14.3% –
Return on capital employed 10.9% 16.7% –
Asset turnover 1.0x 0.4x –
Cash conversion (OCF / net income) 1.4x 1.4x –
Stock comp / revenue 9.4% 1.3% –

Financial Health

11 metrics
MetricARQTAMGNARGX
Debt / assets 22.3% 59.9% –
Debt / equity 0.5x 4.9x –
Net debt / EBITDA – 2.7x –
Debt / FCF 2.8x 5.6x –
Liabilities / assets 54.8% 87.8% –
Equity / assets 45.2% 12.2% –
Interest coverage 2.5x 4.3x 10,120x
Current ratio 2.9x 1.4x –
Quick ratio 2.2x 0.9x –
Cash ratio 1.3x 0.5x –
Altman Z-score 7.59 2.32 –

Shareholder Returns

7 metrics
MetricARQTAMGNARGX
Dividend yield – 2.2% –
Net buyback yield -0.2% – –
Shareholder yield -0.2% 2.2% –
Payout ratio (earnings) – 60.4% –
Payout ratio (FCF) – 51.9% –
Dividend growth (1Y) – 6.3% –
Dividend CAGR (3Y) – 6.7% –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusARQTAMGNARGX
Forward P/E 63.4xFY2026 20.5xFY2026 28.8xFY2026
EPS, next fiscal year $0.50FY2026 $21.81FY2026 $30.63FY2026
EPS growth, next FY – -0.1%FY2026 +56.5%FY2026
EPS growth, the year after +152.0% +7.2% +26.9%
Revenue, next fiscal year $565.04MFY2026 $41.51BFY2026 $6.08BFY2026
Revenue growth, next FY +50.2%FY2026 +12.9%FY2026 +43.1%FY2026
Revenue growth, the year after +17.0% +2.3% +22.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersARQTAMGNARGX
Held by institutions 100.0% 82.7% 46.1%
Institutions holding 271 3,159 504
Change in shares held, QoQ -0.4% +4.5% -2.0%
Institutions buying 138 1,451 264
Institutions selling 98 1,217 160
Buyers to sellers 1.41 1.19 1.65

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ARQTAMGNARGX
ARQT 1.00 0.21 0.17
AMGN 0.21 1.00 0.31
ARGX 0.17 0.31 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ARQT, AMGN and ARGX?

Amgen (AMGN) is the largest by market capitalisation: Arcutis Biotherapeutics (ARQT) $3.98B, Amgen (AMGN) $242.16B, Argenx Se (ARGX) $54.61B.

Which stock is cheaper, ARQT, AMGN and ARGX?

Amgen (AMGN) trades on the lowest price-to-earnings ratio (Arcutis Biotherapeutics (ARQT) 145.0x, Amgen (AMGN) 27.7x, Argenx Se (ARGX) 28.8x). On next year's consensus earnings, Amgen (AMGN) is cheapest (Arcutis Biotherapeutics (ARQT) 63.4x, Amgen (AMGN) 20.5x, Argenx Se (ARGX) 28.8x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Arcutis Biotherapeutics (ARQT) grew revenue fastest over the trailing twelve months: Arcutis Biotherapeutics (ARQT) +76.1%, Amgen (AMGN) +9.1%, Argenx Se (ARGX) +61.5%.

Which company is more profitable?

Argenx Se (ARGX) has the highest net margin (Arcutis Biotherapeutics (ARQT) 6.1%, Amgen (AMGN) 23.0%, Argenx Se (ARGX) 32.3%). On return on invested capital, Amgen (AMGN) leads (Arcutis Biotherapeutics (ARQT) 10.6%, Amgen (AMGN) 14.3%).

Which stock has performed better?

Over the past year Arcutis Biotherapeutics (ARQT) returned the most: Arcutis Biotherapeutics (ARQT) +61.3%, Amgen (AMGN) +53.9%, Argenx Se (ARGX) +6.3%. Over five years, Argenx Se (ARGX) compounded fastest (Arcutis Biotherapeutics (ARQT) +7.9%/yr, Amgen (AMGN) +16.7%/yr, Argenx Se (ARGX) +25.8%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Amgen (AMGN) 2.22%. Arcutis Biotherapeutics (ARQT) and Argenx Se (ARGX) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Amgen (AMGN) has been the steadiest (Arcutis Biotherapeutics (ARQT) 56.7%, Amgen (AMGN) 29.6%, Argenx Se (ARGX) 36.9%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ARQT, AMGN and ARGX?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Amgen (AMGN) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.