ARGX vs REGN vs MRNA Stock Comparison

Argenx Se, Regeneron Pharmaceuticals and Moderna Prices as of Oct 26, 2026 Peers: Industry group
ARGX Argenx Se
$869.33 -9.4% 1M +6.4% 1Y
Market cap
$54.07B
P/E
28.8x
Revenue (TTM)
$5.82B
Div. yield
–
Biotechnology Healthcare
4 wins
MRNA Moderna, Inc.
$198.85 0.0% 1M +643.6% 1Y
Market cap
$83.02B
P/E
–
Revenue (TTM)
$2.23B
Div. yield
–
Biotechnology Healthcare
1 win

Head to Head

11 decided of 12

Regeneron Pharmaceuticals leads on 6 of the 12 questions below (Regeneron Pharmaceuticals 6, Argenx Se 4, Moderna 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionARGXREGNMRNALeader
Larger companyMarket capitalisation $54.07B $83.80B $83.02B REGN
Cheaper on earningsLower P/E, profitable companies only 28.8x 19.4x -26.3x REGN
Cheaper on forward earningsLower price / next fiscal year consensus EPS 28.4x 14.1x — REGN
Faster revenue growthRevenue growth, trailing twelve months +61.5% +9.3% -27.6% ARGX
More profitableNet margin, trailing twelve months 32.3% 27.9% -141.4% ARGX
Better return on capitalReturn on invested capital — 9.6% -43.3% REGN
Less leveragedLower net debt / EBITDA — -1.4x 1.5x REGN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +6.4% +39.7% +643.6% MRNA
Better 5-year returnAnnualised price return, 5 years +25.5%/yr +6.5%/yr -10.2%/yr ARGX
Less volatileAnnualised volatility, 1 year 37.0% 32.9% 131.0% REGN
Higher overall scoreMean of the five percentile scores vs peers 92/100 72/100 57/100 ARGX

Percentile Scorecard

ARGXREGNMRNA

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisARGXREGNMRNA
Valuation 83 #108 of 626 89 #72 of 626 69 #194 of 626
Growth 95 #34 of 604 42 #353 of 604 18 #495 of 604
Profitability 98 #11 of 555 90 #55 of 555 57 #242 of 555
Financial Health – 74 #172 of 658 55 #299 of 658
Shareholder Returns – 65 #129 of 368 85 #56 of 368
Overall 92 72 57
  • ARGX ranked among 673 companies in Pharmaceuticals and Biotechnology
  • REGN ranked among 673 companies in Pharmaceuticals and Biotechnology
  • MRNA ranked among 673 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodARGXREGNMRNASPY
1 month -9.4%+2.5%0.0% -0.8%
3 months -2.2%+21.1%+257.5% +3.5%
6 months +10.9%+8.5%+308.3% +7.0%
Year to date +3.4%+4.6%+574.3% +12.2%
1 year +6.4%+39.7%+643.6% +13.0%
3 years +89.0%+4.2%+176.5% +86.3%
3 years, per year +23.7%+1.4%+40.4% +23.1%
5 years +210.9%+37.0%-41.7% +68.6%
5 years, per year +25.5%+6.5%-10.2% +11.0%
10 years —+122.4%— +258.0%
10 years, per year —+8.3%— +13.6%

Risk

MeasureARGXREGNMRNASPY
Volatility, 1Y 37.0%32.9%131.0% 12.7%
Downside volatility, 1Y 34.6%30.0%79.5% 12.7%
Beta vs S&P 500, 1Y 0.390.462.14 1.00
Return / volatility, 1Y 0.171.214.91 1.02
Max drawdown, 5Y -38.2%-59.8%-93.9% -25.4%
From 52-week high -17.9%-5.2%-19.1% -1.8%
52-week high $1,058.90$852.03$245.81 $779.14
52-week low $663.93$585.31$22.36 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleARGXREGNMRNA
P/E now vs peer median 28.4xmedian 17.1x 19.2xmedian 17.1x -25.1xmedian 17.1x
P/S now vs peer median 9.2xmedian 8.8x 5.3xmedian 8.8x 35.6xmedian 8.8x
EV/EBITDA now vs peer median —median 17.1x 17.6xmedian 17.1x -24.3xmedian 17.1x
P/FCF now vs peer median —median 18.0x 22.1xmedian 18.0x -63.8xmedian 18.0x
P/B now vs peer median —median 2.1x 2.6xmedian 2.1x 11.7xmedian 2.1x
PEG now vs peer median 0.27median 0.31 7.21median 0.31 0.39median 0.31

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsARGXREGNMRNA
Revenue $5.82B $15.53B $2.23B
Gross profit $5.24B $13.18B $521.00M
Operating income $1.74B $3.84B -$3.32B
Net income $1.88B $4.33B -$3.15B
Free cash flow – $3.76B -$1.24B
R&D $1.80B $6.28B $2.88B
EPS (diluted) $28.43 $40.84 $-7.92
Cash & equivalents – $2.46B $1.72B
Total debt – $1.99B $591.00M
Shares (diluted) 66.03M 106.00M 398.00M
Enterprise value $54.07B $50.01B $62.37B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricARGXREGNMRNA
P/E 28.4x 19.2x -25.1x
P/FCF – 22.1x -63.8x
P/Operating cash flow – 17.7x -73.9x
P/S 9.2x 5.3x 35.6x
P/B – 2.6x 11.7x
P/Tangible book – 2.7x 11.7x
EV/EBITDA – 17.6x -24.3x
EV/EBIT 30.9x 20.0x -22.5x
EV/Revenue 9.2x 5.0x 33.6x
EV/FCF – 20.5x -60.1x
EV/Operating cash flow – 16.5x -69.7x
PEG (3Y EPS CAGR) 0.27 7.21 0.39

Growth

14 metrics
MetricARGXREGNMRNA
Revenue growth (1Y) 61.5% 9.3% -27.6%
Revenue CAGR (3Y) 80.5% 7.0% -40.6%
Gross profit growth (1Y) 62.2% 8.4% -67.8%
Gross profit CAGR (3Y) 80.0% 6.4% -56.0%
Operating income growth (1Y) 120.6% 0.1% -1.4%
Operating income CAGR (3Y) 85.1% -3.9% -103.9%
Net income growth (1Y) 22.5% -2.9% -8.5%
Net income CAGR (3Y) 115.5% 0.2% -66.4%
EPS growth (1Y) 20.9% -0.5% -5.8%
EPS CAGR (3Y) 104.8% 2.7% -65.1%
Operating cash flow growth (1Y) – -1.3% 60.2%
Operating cash flow CAGR (3Y) – -0.4% -68.1%
Free cash flow growth (1Y) – -2.4% 64.4%
Free cash flow CAGR (3Y) – -3.3% -18.2%

Profitability

14 metrics
MetricARGXREGNMRNA
Gross margin 90.0% 84.9% 23.4%
EBITDA margin – 28.1% -138.2%
Operating margin 29.9% 24.7% -149.0%
Pretax margin 32.6% 33.3% -138.6%
Net margin 32.3% 27.9% -141.4%
FCF margin – 24.2% -55.8%
Operating cash flow margin – 30.1% -48.2%
Return on equity – 13.7% -44.5%
Return on assets – 10.5% -28.1%
Return on invested capital – 9.6% -43.3%
Return on capital employed – 10.7% -38.2%
Asset turnover – 0.4x 0.2x
Cash conversion (OCF / net income) – 1.1x 0.3x
Stock comp / revenue – 6.4% 20.7%

Financial Health

11 metrics
MetricARGXREGNMRNA
Debt / assets – 4.8% 5.4%
Debt / equity – 0.1x 0.1x
Net debt / EBITDA – -1.4x 1.5x
Debt / FCF – 0.5x -0.5x
Liabilities / assets – 24.0% 38.3%
Equity / assets – 76.0% 61.7%
Interest coverage 10,120x 69.4x –
Current ratio – 3.3x 2.3x
Quick ratio – 2.6x 2.0x
Cash ratio – 1.4x 2.0x
Altman Z-score – 7.28 11.55

Shareholder Returns

7 metrics
MetricARGXREGNMRNA
Dividend yield – 0.5% –
Net buyback yield – 3.1% -0.1%
Shareholder yield – 3.5% -0.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusARGXREGNMRNA
Forward P/E 28.4xFY2026 14.1xFY2026 –
EPS, next fiscal year $30.63FY2026 $57.08FY2026 $-8.02FY2026
EPS growth, next FY +56.5%FY2026 +28.8%FY2026 –
EPS growth, the year after +26.9% +15.5% –
Revenue, next fiscal year $6.08BFY2026 $17.05BFY2026 $2.04BFY2026
Revenue growth, next FY +43.1%FY2026 +18.9%FY2026 +5.1%FY2026
Revenue growth, the year after +22.9% +13.0% +26.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersARGXREGNMRNA
Held by institutions 46.1% 66.2% 80.2%
Institutions holding 504 1,325 784
Change in shares held, QoQ -2.0% +3.8% +3.4%
Institutions buying 264 604 402
Institutions selling 160 534 238
Buyers to sellers 1.65 1.13 1.69

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ARGXREGNMRNA
ARGX 1.00 0.23 0.17
REGN 0.23 1.00 0.26
MRNA 0.17 0.26 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ARGX, REGN and MRNA?

Regeneron Pharmaceuticals (REGN) is the largest by market capitalisation: Argenx Se (ARGX) $54.07B, Regeneron Pharmaceuticals (REGN) $83.80B, Moderna (MRNA) $83.02B.

Which stock is cheaper, ARGX, REGN and MRNA?

Regeneron Pharmaceuticals (REGN) trades on the lowest price-to-earnings ratio (Argenx Se (ARGX) 28.8x, Regeneron Pharmaceuticals (REGN) 19.4x, Moderna (MRNA) -26.3x). On next year's consensus earnings, Regeneron Pharmaceuticals (REGN) is cheapest (Argenx Se (ARGX) 28.4x, Regeneron Pharmaceuticals (REGN) 14.1x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Argenx Se (ARGX) grew revenue fastest over the trailing twelve months: Argenx Se (ARGX) +61.5%, Regeneron Pharmaceuticals (REGN) +9.3%, Moderna (MRNA) -27.6%.

Which company is more profitable?

Argenx Se (ARGX) has the highest net margin (Argenx Se (ARGX) 32.3%, Regeneron Pharmaceuticals (REGN) 27.9%, Moderna (MRNA) -141.4%). On return on invested capital, Regeneron Pharmaceuticals (REGN) leads (Regeneron Pharmaceuticals (REGN) 9.6%, Moderna (MRNA) -43.3%).

Which stock has performed better?

Over the past year Moderna (MRNA) returned the most: Argenx Se (ARGX) +6.4%, Regeneron Pharmaceuticals (REGN) +39.7%, Moderna (MRNA) +643.6%. Over five years, Argenx Se (ARGX) compounded fastest (Argenx Se (ARGX) +25.5%/yr, Regeneron Pharmaceuticals (REGN) +6.5%/yr, Moderna (MRNA) -10.2%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Regeneron Pharmaceuticals (REGN) has been the steadiest (Argenx Se (ARGX) 37.0%, Regeneron Pharmaceuticals (REGN) 32.9%, Moderna (MRNA) 131.0%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ARGX, REGN and MRNA?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Regeneron Pharmaceuticals (REGN) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.