ARGX vs MRNA vs BNTX Stock Comparison

Argenx Se, Moderna and BioNTech SE Prices as of Oct 26, 2026 Peers: Industry group
ARGX Argenx Se
$869.33 -9.4% 1M +6.4% 1Y
Market cap
$53.71B
P/E
28.6x
Revenue (TTM)
$5.82B
Div. yield
–
Biotechnology Healthcare
5 wins
MRNA Moderna, Inc.
$198.85 0.0% 1M +643.6% 1Y
Market cap
$81.68B
P/E
–
Revenue (TTM)
$2.23B
Div. yield
–
Biotechnology Healthcare
3 wins
BNTX BioNTech SE
$86.86 -11.8% 1M -17.8% 1Y
Market cap
$21.06B
P/E
–
Revenue (TTM)
$3.09B
Div. yield
–
Biotechnology Healthcare
1 win

Head to Head

9 decided of 12

Argenx Se leads on 5 of the 12 questions below (Argenx Se 5, Moderna 3, BioNTech SE 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionARGXMRNABNTXLeader
Larger companyMarket capitalisation $53.71B $81.68B $21.06B MRNA
Cheaper on earningsLower P/E, profitable companies only 28.6x -25.9x -10.7x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 28.4x — — –
Faster revenue growthRevenue growth, trailing twelve months +61.5% -27.6% -1.1% ARGX
More profitableNet margin, trailing twelve months 32.3% -141.4% -63.5% ARGX
Better return on capitalReturn on invested capital — -43.3% -10.7% BNTX
Less leveragedLower net debt / EBITDA — 1.5x 8.7x MRNA
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +6.4% +643.6% -17.8% MRNA
Better 5-year returnAnnualised price return, 5 years +25.5%/yr -10.2%/yr -20.8%/yr ARGX
Less volatileAnnualised volatility, 1 year 37.0% 131.0% 46.7% ARGX
Higher overall scoreMean of the five percentile scores vs peers 92/100 57/100 64/100 ARGX

Percentile Scorecard

ARGXMRNABNTX

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisARGXMRNABNTX
Valuation 83 #108 of 626 69 #194 of 626 91 #59 of 626
Growth 95 #34 of 604 18 #495 of 604 14 #522 of 604
Profitability 98 #11 of 555 57 #242 of 555 76 #132 of 555
Financial Health – 55 #299 of 658 89 #72 of 658
Shareholder Returns – 85 #56 of 368 51 #180 of 368
Overall 92 57 64
  • ARGX ranked among 673 companies in Pharmaceuticals and Biotechnology
  • MRNA ranked among 673 companies in Pharmaceuticals and Biotechnology
  • BNTX ranked among 673 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodARGXMRNABNTXSPY
1 month -9.4%0.0%-11.8% -0.8%
3 months -2.2%+257.5%-4.6% +3.5%
6 months +10.9%+308.3%-14.9% +7.0%
Year to date +3.4%+574.3%-8.8% +12.2%
1 year +6.4%+643.6%-17.8% +13.0%
3 years +89.0%+176.5%-4.8% +86.3%
3 years, per year +23.7%+40.4%-1.6% +23.1%
5 years +210.9%-41.7%-68.8% +68.6%
5 years, per year +25.5%-10.2%-20.8% +11.0%

Risk

MeasureARGXMRNABNTXSPY
Volatility, 1Y 37.0%131.0%46.7% 12.7%
Downside volatility, 1Y 34.6%79.5%46.5% 12.7%
Beta vs S&P 500, 1Y 0.392.140.95 1.00
Return / volatility, 1Y 0.174.91-0.38 1.02
Max drawdown, 5Y -38.2%-93.9%-78.4% -25.4%
From 52-week high -17.9%-19.1%-27.2% -1.8%
52-week high $1,058.90$245.81$119.34 $779.14
52-week low $663.93$22.36$83.89 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleARGXMRNABNTX
P/E now vs peer median 28.4xmedian 17.1x -25.1xmedian 17.1x -10.7xmedian 17.1x
P/S now vs peer median 9.2xmedian 8.8x 35.6xmedian 8.8x 7.1xmedian 8.8x
EV/EBITDA now vs peer median —median 17.1x -24.3xmedian 17.1x -5.6xmedian 17.1x
P/FCF now vs peer median —median 18.0x -63.8xmedian 18.0x 21.2xmedian 18.0x
P/B now vs peer median —median 2.1x 11.7xmedian 2.1x 1.1xmedian 2.1x
PEG now vs peer median 0.27median 0.31 0.39median 0.31 0.31median 0.31

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsARGXMRNABNTX
Revenue $5.82B $2.23B $3.09B
Gross profit $5.24B $521.00M $2.34B
Operating income $1.74B -$3.32B -$2.33B
Net income $1.88B -$3.15B -$1.97B
Free cash flow – -$1.24B $1.04B
R&D $1.80B $2.88B $2.54B
EPS (diluted) $28.43 $-7.92 $-8.13
Cash & equivalents – $1.72B $11.13B
Total debt – $591.00M $102.80M
Shares (diluted) 66.03M 398.00M 241.70M
Enterprise value $53.71B $61.03B -$25.42B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricARGXMRNABNTX
P/E 28.4x -25.1x -10.7x
P/FCF – -63.8x 21.2x
P/Operating cash flow – -73.9x 27.7x
P/S 9.2x 35.6x 7.1x
P/B – 11.7x 1.1x
P/Tangible book – 11.7x 1.1x
EV/EBITDA – -24.3x -5.6x
EV/EBIT 30.9x -22.5x -3.7x
EV/Revenue 9.2x 33.6x 2.8x
EV/FCF – -60.1x 8.3x
EV/Operating cash flow – -69.7x 10.9x
PEG (3Y EPS CAGR) 0.27 0.39 0.31

Growth

14 metrics
MetricARGXMRNABNTX
Revenue growth (1Y) 61.5% -27.6% -1.1%
Revenue CAGR (3Y) 80.5% -40.6% -31.0%
Gross profit growth (1Y) 62.2% -67.8% -6.4%
Gross profit CAGR (3Y) 80.0% -56.0% -34.2%
Operating income growth (1Y) 120.6% -1.4% -142.6%
Operating income CAGR (3Y) 85.1% -103.9% -33.8%
Net income growth (1Y) 22.5% -8.5% -417.0%
Net income CAGR (3Y) 115.5% -66.4% -34.6%
EPS growth (1Y) 20.9% -5.8% -393.7%
EPS CAGR (3Y) 104.8% -65.1% -34.9%
Operating cash flow growth (1Y) – 60.2% 142.8%
Operating cash flow CAGR (3Y) – -68.1% -56.6%
Free cash flow growth (1Y) – 64.4% 164.1%
Free cash flow CAGR (3Y) – -18.2% -53.1%

Profitability

14 metrics
MetricARGXMRNABNTX
Gross margin 90.0% 23.4% 75.5%
EBITDA margin – -138.2% -49.7%
Operating margin 29.9% -149.0% -75.2%
Pretax margin 32.6% -138.6% -61.4%
Net margin 32.3% -141.4% -63.5%
FCF margin – -55.8% 33.6%
Operating cash flow margin – -48.2% 25.6%
Return on equity – -44.5% -10.3%
Return on assets – -28.1% -9.0%
Return on invested capital – -43.3% -10.7%
Return on capital employed – -38.2% -9.9%
Asset turnover – 0.2x 0.1x
Cash conversion (OCF / net income) – 0.3x -0.4x
Stock comp / revenue – 20.7% 3.6%

Financial Health

11 metrics
MetricARGXMRNABNTX
Debt / assets – 5.4% 0.4%
Debt / equity – 0.1x 0.0x
Net debt / EBITDA – 1.5x 8.7x
Debt / FCF – -0.5x 0.1x
Liabilities / assets – 38.3% 12.7%
Equity / assets – 61.7% 87.3%
Interest coverage 10,120x – -41.1x
Current ratio – 2.3x 65.1x
Quick ratio – 2.0x 50.7x
Cash ratio – 2.0x 50.0x
Altman Z-score – 11.55 6.30

Shareholder Returns

7 metrics
MetricARGXMRNABNTX
Dividend yield – – –
Net buyback yield – -0.1% -3.0%
Shareholder yield – -0.1% -3.0%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusARGXMRNABNTX
Forward P/E 28.4xFY2026 – –
EPS, next fiscal year $30.63FY2026 $-8.02FY2026 $-6.21FY2026
EPS growth, next FY +56.5%FY2026 – –
EPS growth, the year after +26.9% – –
Revenue, next fiscal year $6.08BFY2026 $2.04BFY2026 $1.90BFY2026
Revenue growth, next FY +43.1%FY2026 +5.1%FY2026 -43.7%FY2026
Revenue growth, the year after +22.9% +26.8% +11.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersARGXMRNABNTX
Held by institutions 46.1% 80.2% 19.4%
Institutions holding 504 784 281
Change in shares held, QoQ -2.0% +3.4% -1.2%
Institutions buying 264 402 136
Institutions selling 160 238 73
Buyers to sellers 1.65 1.69 1.86

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ARGXMRNABNTX
ARGX 1.00 0.17 0.23
MRNA 0.17 1.00 0.59
BNTX 0.23 0.59 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ARGX, MRNA and BNTX?

Moderna (MRNA) is the largest by market capitalisation: Argenx Se (ARGX) $53.71B, Moderna (MRNA) $81.68B, BioNTech SE (BNTX) $21.06B.

Which company is growing faster?

Argenx Se (ARGX) grew revenue fastest over the trailing twelve months: Argenx Se (ARGX) +61.5%, Moderna (MRNA) -27.6%, BioNTech SE (BNTX) -1.1%.

Which company is more profitable?

Argenx Se (ARGX) has the highest net margin (Argenx Se (ARGX) 32.3%, Moderna (MRNA) -141.4%, BioNTech SE (BNTX) -63.5%). On return on invested capital, BioNTech SE (BNTX) leads (Moderna (MRNA) -43.3%, BioNTech SE (BNTX) -10.7%).

Which stock has performed better?

Over the past year Moderna (MRNA) returned the most: Argenx Se (ARGX) +6.4%, Moderna (MRNA) +643.6%, BioNTech SE (BNTX) -17.8%. Over five years, Argenx Se (ARGX) compounded fastest (Argenx Se (ARGX) +25.5%/yr, Moderna (MRNA) -10.2%/yr, BioNTech SE (BNTX) -20.8%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Argenx Se (ARGX) has been the steadiest (Argenx Se (ARGX) 37.0%, Moderna (MRNA) 131.0%, BioNTech SE (BNTX) 46.7%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ARGX, MRNA and BNTX?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Argenx Se (ARGX) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.