ARGX vs MRNA vs BIIB Stock Comparison

Argenx Se, Moderna and Biogen Prices as of Oct 28, 2026 Peers: Industry group
ARGX Argenx Se
$891.76 -8.3% 1M +6.6% 1Y
Market cap
$55.00B
P/E
29.3x
Revenue (TTM)
$5.82B
Div. yield
–
Biotechnology Healthcare
5 wins
MRNA Moderna, Inc.
$214.16 +8.6% 1M +744.8% 1Y
Market cap
$88.13B
P/E
–
Revenue (TTM)
$2.23B
Div. yield
–
Biotechnology Healthcare
3 wins
BIIB Biogen Inc.
$244.05 +6.7% 1M +63.6% 1Y
Market cap
$36.94B
P/E
106.3x
Revenue (TTM)
$10.30B
Div. yield
–
Biotechnology Healthcare
3 wins

Head to Head

11 decided of 12

Argenx Se leads on 5 of the 12 questions below (Argenx Se 5, Moderna 3, Biogen 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionARGXMRNABIIBLeader
Larger companyMarket capitalisation $55.00B $88.13B $36.94B MRNA
Cheaper on earningsLower P/E, profitable companies only 29.3x -28.0x 106.3x ARGX
Cheaper on forward earningsLower price / next fiscal year consensus EPS 29.1x — 19.1x BIIB
Faster revenue growthRevenue growth, trailing twelve months +61.5% -27.6% +2.3% ARGX
More profitableNet margin, trailing twelve months 32.3% -141.4% 3.4% ARGX
Better return on capitalReturn on invested capital — -43.3% 1.3% BIIB
Less leveragedLower net debt / EBITDA — 1.5x 4.5x MRNA
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +6.6% +744.8% +63.6% MRNA
Better 5-year returnAnnualised price return, 5 years +24.2%/yr -9.1%/yr -1.8%/yr ARGX
Less volatileAnnualised volatility, 1 year 36.9% 130.6% 34.2% BIIB
Higher overall scoreMean of the five percentile scores vs peers 92/100 57/100 59/100 ARGX

Percentile Scorecard

ARGXMRNABIIB

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisARGXMRNABIIB
Valuation 84 #101 of 625 69 #192 of 625 92 #54 of 625
Growth 94 #35 of 602 19 #488 of 602 26 #446 of 602
Profitability 98 #11 of 549 57 #235 of 549 87 #73 of 549
Financial Health – 55 #298 of 654 33 #437 of 654
Shareholder Returns – 85 #57 of 367 –
Overall 92 57 59
  • ARGX ranked among 672 companies in Pharmaceuticals and Biotechnology
  • MRNA ranked among 672 companies in Pharmaceuticals and Biotechnology
  • BIIB ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodARGXMRNABIIBSPY
1 month -8.3%+8.6%+6.7% +0.9%
3 months +1.0%+293.0%+16.6% +5.9%
6 months +14.9%+368.4%+25.6% +8.5%
Year to date +6.0%+626.2%+38.7% +13.3%
1 year +6.6%+744.8%+63.6% +12.4%
3 years +93.9%+197.8%+4.1% +88.1%
3 years, per year +24.7%+43.9%+1.3% +23.5%
5 years +195.3%-38.0%-8.5% +68.2%
5 years, per year +24.2%-9.1%-1.8% +11.0%
10 years ——-14.0% +263.4%
10 years, per year ——-1.5% +13.8%

Risk

MeasureARGXMRNABIIBSPY
Volatility, 1Y 36.9%130.6%34.2% 12.7%
Downside volatility, 1Y 34.6%79.5%32.7% 12.7%
Beta vs S&P 500, 1Y 0.392.160.25 1.00
Return / volatility, 1Y 0.185.701.86 0.98
Max drawdown, 5Y -38.2%-93.9%-64.4% -25.4%
From 52-week high -15.8%-12.9%-3.9% -0.9%
52-week high $1,058.90$245.81$253.84 $779.14
52-week low $663.93$22.36$147.86 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleARGXMRNABIIB
P/E now vs peer median 29.1xmedian 17.4x -27.1xmedian 17.4x 103.8xmedian 17.4x
P/S now vs peer median 9.5xmedian 9.1x 38.4xmedian 9.1x 3.5xmedian 9.1x
EV/EBITDA now vs peer median —median 17.1x -26.3xmedian 17.1x 31.7xmedian 17.1x
P/FCF now vs peer median —median 19.0x -68.7xmedian 19.0x 17.4xmedian 19.0x
P/B now vs peer median —median 2.2x 12.6xmedian 2.2x 1.9xmedian 2.2x
PEG now vs peer median 0.28median 0.34 0.42median 0.34 -2.70median 0.34

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsARGXMRNABIIB
Revenue $5.82B $2.23B $10.30B
Gross profit $5.24B $521.00M $7.62B
Operating income $1.74B -$3.32B $445.10M
Net income $1.88B -$3.15B $347.50M
Free cash flow – -$1.24B $2.07B
R&D $1.80B $2.88B $2.15B
EPS (diluted) $28.43 $-7.92 $2.35
Cash & equivalents – $1.72B $1.30B
Total debt – $591.00M $7.29B
Shares (diluted) 66.03M 398.00M 147.80M
Enterprise value $55.00B $67.49B $26.26B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricARGXMRNABIIB
P/E 29.1x -27.1x 103.8x
P/FCF – -68.7x 17.4x
P/Operating cash flow – -79.6x 16.1x
P/S 9.5x 38.4x 3.5x
P/B – 12.6x 1.9x
P/Tangible book – 12.6x 6.5x
EV/EBITDA – -26.3x 31.7x
EV/EBIT 31.7x -24.4x 94.5x
EV/Revenue 9.5x 36.3x 4.1x
EV/FCF – -65.0x 20.3x
EV/Operating cash flow – -75.4x 18.7x
PEG (3Y EPS CAGR) 0.28 0.42 -2.70

Growth

14 metrics
MetricARGXMRNABIIB
Revenue growth (1Y) 61.5% -27.6% 2.3%
Revenue CAGR (3Y) 80.5% -40.6% 1.0%
Gross profit growth (1Y) 62.2% -67.8% 0.6%
Gross profit CAGR (3Y) 80.0% -56.0% 0.5%
Operating income growth (1Y) 120.6% -1.4% -76.6%
Operating income CAGR (3Y) 85.1% -103.9% -34.8%
Net income growth (1Y) 22.5% -8.5% -78.4%
Net income CAGR (3Y) 115.5% -66.4% -38.1%
EPS growth (1Y) 20.9% -5.8% -78.5%
EPS CAGR (3Y) 104.8% -65.1% -38.5%
Operating cash flow growth (1Y) – 60.2% -8.4%
Operating cash flow CAGR (3Y) – -68.1% 18.2%
Free cash flow growth (1Y) – 64.4% -10.1%
Free cash flow CAGR (3Y) – -18.2% 24.9%

Profitability

14 metrics
MetricARGXMRNABIIB
Gross margin 90.0% 23.4% 74.0%
EBITDA margin – -138.2% 12.9%
Operating margin 29.9% -149.0% 4.3%
Pretax margin 32.6% -138.6% 4.3%
Net margin 32.3% -141.4% 3.4%
FCF margin – -55.8% 20.1%
Operating cash flow margin – -48.2% 21.8%
Return on equity – -44.5% 1.8%
Return on assets – -28.1% 1.1%
Return on invested capital – -43.3% 1.3%
Return on capital employed – -38.2% 1.6%
Asset turnover – 0.2x 0.3x
Cash conversion (OCF / net income) – 0.3x 6.5x
Stock comp / revenue – 20.7% 2.9%

Financial Health

11 metrics
MetricARGXMRNABIIB
Debt / assets – 5.4% 22.7%
Debt / equity – 0.1x 0.4x
Net debt / EBITDA – 1.5x 4.5x
Debt / FCF – -0.5x 3.5x
Liabilities / assets – 38.3% 41.0%
Equity / assets – 61.7% 59.0%
Interest coverage 10,120x – –
Current ratio – 2.3x 1.9x
Quick ratio – 2.0x 0.9x
Cash ratio – 2.0x 0.3x
Altman Z-score – 12.42 3.07

Shareholder Returns

7 metrics
MetricARGXMRNABIIB
Dividend yield – – –
Net buyback yield – -0.1% –
Shareholder yield – -0.1% –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusARGXMRNABIIB
Forward P/E 29.1xFY2026 – 19.1xFY2026
EPS, next fiscal year $30.63FY2026 $-8.02FY2026 $12.81FY2026
EPS growth, next FY +56.5%FY2026 – -16.2%FY2026
EPS growth, the year after +26.9% – +36.5%
Revenue, next fiscal year $6.08BFY2026 $2.04BFY2026 $9.96BFY2026
Revenue growth, next FY +43.1%FY2026 +5.1%FY2026 +0.7%FY2026
Revenue growth, the year after +22.9% +26.8% +11.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersARGXMRNABIIB
Held by institutions 46.1% 80.2% 96.4%
Institutions holding 504 784 1,036
Change in shares held, QoQ -2.0% +3.4% +6.0%
Institutions buying 264 402 548
Institutions selling 160 238 294
Buyers to sellers 1.65 1.69 1.86

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ARGXMRNABIIB
ARGX 1.00 0.17 0.21
MRNA 0.17 1.00 0.22
BIIB 0.21 0.22 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ARGX, MRNA and BIIB?

Moderna (MRNA) is the largest by market capitalisation: Argenx Se (ARGX) $55.00B, Moderna (MRNA) $88.13B, Biogen (BIIB) $36.94B.

Which stock is cheaper, ARGX, MRNA and BIIB?

Argenx Se (ARGX) trades on the lowest price-to-earnings ratio (Argenx Se (ARGX) 29.3x, Moderna (MRNA) -28.0x, Biogen (BIIB) 106.3x). On next year's consensus earnings, Biogen (BIIB) is cheapest (Argenx Se (ARGX) 29.1x, Biogen (BIIB) 19.1x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Argenx Se (ARGX) grew revenue fastest over the trailing twelve months: Argenx Se (ARGX) +61.5%, Moderna (MRNA) -27.6%, Biogen (BIIB) +2.3%.

Which company is more profitable?

Argenx Se (ARGX) has the highest net margin (Argenx Se (ARGX) 32.3%, Moderna (MRNA) -141.4%, Biogen (BIIB) 3.4%). On return on invested capital, Biogen (BIIB) leads (Moderna (MRNA) -43.3%, Biogen (BIIB) 1.3%).

Which stock has performed better?

Over the past year Moderna (MRNA) returned the most: Argenx Se (ARGX) +6.6%, Moderna (MRNA) +744.8%, Biogen (BIIB) +63.6%. Over five years, Argenx Se (ARGX) compounded fastest (Argenx Se (ARGX) +24.2%/yr, Moderna (MRNA) -9.1%/yr, Biogen (BIIB) -1.8%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Biogen (BIIB) has been the steadiest (Argenx Se (ARGX) 36.9%, Moderna (MRNA) 130.6%, Biogen (BIIB) 34.2%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ARGX, MRNA and BIIB?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Argenx Se (ARGX) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.