ARGX vs GRFS vs MRNA Stock Comparison

Argenx Se, Grifols and Moderna Prices as of Oct 27, 2026 Peers: Industry group
ARGX Argenx Se
$882.48 -8.0% 1M +6.3% 1Y
Market cap
$54.54B
P/E
29.1x
Revenue (TTM)
$5.82B
Div. yield
–
Biotechnology Healthcare
4 wins
GRFS Grifols SA
$8.10 +10.2% 1M -13.6% 1Y
Market cap
$5.50B
P/E
12.1x
Revenue (TTM)
—
Div. yield
–
Biotechnology Healthcare
3 wins
MRNA Moderna, Inc.
$207.97 +4.6% 1M +680.1% 1Y
Market cap
$85.21B
P/E
–
Revenue (TTM)
$2.23B
Div. yield
–
Biotechnology Healthcare
2 wins

Head to Head

9 decided of 12

Argenx Se leads on 4 of the 12 questions below (Argenx Se 4, Grifols 3, Moderna 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionARGXGRFSMRNALeader
Larger companyMarket capitalisation $54.54B $5.50B $85.21B MRNA
Cheaper on earningsLower P/E, profitable companies only 29.1x 12.1x -27.0x GRFS
Cheaper on forward earningsLower price / next fiscal year consensus EPS 28.8x 8.6x — GRFS
Faster revenue growthRevenue growth, trailing twelve months +61.5% — -27.6% ARGX
More profitableNet margin, trailing twelve months 32.3% — -141.4% ARGX
Better return on capitalReturn on invested capital — — -43.3% –
Less leveragedLower net debt / EBITDA — — 1.5x –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +6.3% -13.6% +680.1% MRNA
Better 5-year returnAnnualised price return, 5 years +25.8%/yr -9.4%/yr -9.8%/yr ARGX
Less volatileAnnualised volatility, 1 year 36.9% 32.4% 130.8% GRFS
Higher overall scoreMean of the five percentile scores vs peers 92/100 56/100 57/100 ARGX

Percentile Scorecard

ARGXGRFSMRNA

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisARGXGRFSMRNA
Valuation 84 #99 of 625 99 #7 of 625 69 #193 of 625
Growth 94 #35 of 602 – 18 #493 of 602
Profitability 98 #11 of 551 – 57 #239 of 551
Financial Health – 14 #564 of 656 55 #298 of 656
Shareholder Returns – 56 #161 of 365 85 #57 of 365
Overall 92 56 57
  • ARGX ranked among 672 companies in Pharmaceuticals and Biotechnology
  • GRFS ranked among 672 companies in Pharmaceuticals and Biotechnology
  • MRNA ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodARGXGRFSMRNASPY
1 month -8.0%+10.2%+4.6% -0.2%
3 months +1.2%+1.2%+272.6% +3.9%
6 months +13.9%+0.4%+341.2% +8.2%
Year to date +4.9%-13.4%+605.2% +12.9%
1 year +6.3%-13.6%+680.1% +12.3%
3 years +91.9%+3.3%+189.2% +87.4%
3 years, per year +24.3%+1.1%+42.5% +23.3%
5 years +214.2%-39.0%-40.2% +67.9%
5 years, per year +25.8%-9.4%-9.8% +10.9%
10 years —-44.7%— +261.1%
10 years, per year —-5.8%— +13.7%

Risk

MeasureARGXGRFSMRNASPY
Volatility, 1Y 36.9%32.4%130.8% 12.7%
Downside volatility, 1Y 34.6%34.1%79.5% 12.7%
Beta vs S&P 500, 1Y 0.390.952.15 1.00
Return / volatility, 1Y 0.17-0.425.20 0.97
Max drawdown, 5Y -38.2%-58.8%-93.9% -25.4%
From 52-week high -16.7%-16.7%-15.4% -1.2%
52-week high $1,058.90$9.72$245.81 $779.14
52-week low $663.93$7.02$22.36 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleARGXGRFSMRNA
P/E now vs peer median 28.8xmedian 17.2x 12.1xmedian 17.2x -26.3xmedian 17.2x
P/S now vs peer median 9.4xmedian 9.0x 0.6xmedian 9.0x 37.2xmedian 9.0x
EV/EBITDA now vs peer median —median 16.3x —median 16.3x -25.5xmedian 16.3x
P/FCF now vs peer median —median 18.7x 7.8xmedian 18.7x -66.7xmedian 18.7x
P/B now vs peer median —median 2.2x 0.6xmedian 2.2x 12.3xmedian 2.2x
PEG now vs peer median 0.27median 0.33 —median 0.33 0.40median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsARGXGRFSMRNA
Revenue $5.82B – $2.23B
Gross profit $5.24B – $521.00M
Operating income $1.74B – -$3.32B
Net income $1.88B – -$3.15B
Free cash flow – – -$1.24B
R&D $1.80B – $2.88B
EPS (diluted) $28.43 – $-7.92
Cash & equivalents – $969.15M $1.72B
Total debt – $44.00B $591.00M
Shares (diluted) 66.03M 681.57M 398.00M
Enterprise value $54.54B $1.84B $64.56B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricARGXGRFSMRNA
P/E 28.8x 12.1x -26.3x
P/FCF – 7.8x -66.7x
P/Operating cash flow – – -77.3x
P/S 9.4x 0.6x 37.2x
P/B – 0.6x 12.3x
P/Tangible book – 1.0x 12.3x
EV/EBITDA – – -25.5x
EV/EBIT 31.4x – -23.6x
EV/Revenue 9.4x – 35.2x
EV/FCF – – -63.0x
EV/Operating cash flow – – -73.1x
PEG (3Y EPS CAGR) 0.27 – 0.40

Growth

14 metrics
MetricARGXGRFSMRNA
Revenue growth (1Y) 61.5% – -27.6%
Revenue CAGR (3Y) 80.5% – -40.6%
Gross profit growth (1Y) 62.2% – -67.8%
Gross profit CAGR (3Y) 80.0% – -56.0%
Operating income growth (1Y) 120.6% – -1.4%
Operating income CAGR (3Y) 85.1% – -103.9%
Net income growth (1Y) 22.5% – -8.5%
Net income CAGR (3Y) 115.5% – -66.4%
EPS growth (1Y) 20.9% – -5.8%
EPS CAGR (3Y) 104.8% – -65.1%
Operating cash flow growth (1Y) – – 60.2%
Operating cash flow CAGR (3Y) – – -68.1%
Free cash flow growth (1Y) – – 64.4%
Free cash flow CAGR (3Y) – – -18.2%

Profitability

14 metrics
MetricARGXGRFSMRNA
Gross margin 90.0% – 23.4%
EBITDA margin – – -138.2%
Operating margin 29.9% – -149.0%
Pretax margin 32.6% – -138.6%
Net margin 32.3% – -141.4%
FCF margin – – -55.8%
Operating cash flow margin – – -48.2%
Return on equity – – -44.5%
Return on assets – – -28.1%
Return on invested capital – – -43.3%
Return on capital employed – – -38.2%
Asset turnover – – 0.2x
Cash conversion (OCF / net income) – – 0.3x
Stock comp / revenue – – 20.7%

Financial Health

11 metrics
MetricARGXGRFSMRNA
Debt / assets – 48.9% 5.4%
Debt / equity – 1.3x 0.1x
Net debt / EBITDA – – 1.5x
Debt / FCF – – -0.5x
Liabilities / assets – 61.4% 38.3%
Equity / assets – 38.6% 61.7%
Interest coverage 10,120x – –
Current ratio – 2.5x 2.3x
Quick ratio – 0.8x 2.0x
Cash ratio – 0.4x 2.0x
Altman Z-score – – 12.07

Shareholder Returns

7 metrics
MetricARGXGRFSMRNA
Dividend yield – 1.4% –
Net buyback yield – – -0.1%
Shareholder yield – 1.4% -0.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusARGXGRFSMRNA
Forward P/E 28.8xFY2026 8.6xFY2026 –
EPS, next fiscal year $30.63FY2026 $0.94FY2026 $-8.02FY2026
EPS growth, next FY +56.5%FY2026 +10.6%FY2026 –
EPS growth, the year after +26.9% +26.6% –
Revenue, next fiscal year $6.08BFY2026 $8.88BFY2026 $2.04BFY2026
Revenue growth, next FY +43.1%FY2026 +0.0%FY2026 +5.1%FY2026
Revenue growth, the year after +22.9% +10.3% +26.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersARGXGRFSMRNA
Held by institutions 46.1% 21.0% 80.2%
Institutions holding 504 166 784
Change in shares held, QoQ -2.0% -0.5% +3.4%
Institutions buying 264 73 402
Institutions selling 160 65 238
Buyers to sellers 1.65 1.12 1.69

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ARGXGRFSMRNA
ARGX 1.00 0.15 0.17
GRFS 0.15 1.00 0.26
MRNA 0.17 0.26 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ARGX, GRFS and MRNA?

Moderna (MRNA) is the largest by market capitalisation: Argenx Se (ARGX) $54.54B, Grifols (GRFS) $5.50B, Moderna (MRNA) $85.21B.

Which stock is cheaper, ARGX, GRFS and MRNA?

Grifols (GRFS) trades on the lowest price-to-earnings ratio (Argenx Se (ARGX) 29.1x, Grifols (GRFS) 12.1x, Moderna (MRNA) -27.0x). On next year's consensus earnings, Grifols (GRFS) is cheapest (Argenx Se (ARGX) 28.8x, Grifols (GRFS) 8.6x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Argenx Se (ARGX) grew revenue fastest over the trailing twelve months: Argenx Se (ARGX) +61.5%, Moderna (MRNA) -27.6%.

Which company is more profitable?

Argenx Se (ARGX) has the highest net margin (Argenx Se (ARGX) 32.3%, Moderna (MRNA) -141.4%).

Which stock has performed better?

Over the past year Moderna (MRNA) returned the most: Argenx Se (ARGX) +6.3%, Grifols (GRFS) -13.6%, Moderna (MRNA) +680.1%. Over five years, Argenx Se (ARGX) compounded fastest (Argenx Se (ARGX) +25.8%/yr, Grifols (GRFS) -9.4%/yr, Moderna (MRNA) -9.8%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Grifols (GRFS) has been the steadiest (Argenx Se (ARGX) 36.9%, Grifols (GRFS) 32.4%, Moderna (MRNA) 130.8%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ARGX, GRFS and MRNA?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Argenx Se (ARGX) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.