AMGN vs GRFS vs ARQT Stock Comparison

Amgen, Grifols and Arcutis Biotherapeutics Prices as of Oct 26, 2026 Peers: Industry group
AMGN Amgen Inc
$444.63 +7.2% 1M +52.4% 1Y
Market cap
$242.06B
P/E
27.7x
Revenue (TTM)
$38.10B
Div. yield
0.02%
Biotechnology Healthcare
5 wins
GRFS Grifols SA
$7.92 +7.8% 1M -16.3% 1Y
Market cap
$5.52B
P/E
11.9x
Revenue (TTM)
—
Div. yield
–
Biotechnology Healthcare
2 wins

Head to Head

10 decided of 12

Amgen leads on 5 of the 12 questions below (Amgen 5, Arcutis Biotherapeutics 3, Grifols 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionAMGNGRFSARQTLeader
Larger companyMarket capitalisation $242.06B $5.52B $4.13B AMGN
Cheaper on earningsLower P/E, profitable companies only 27.7x 11.9x 145.0x GRFS
Cheaper on forward earningsLower price / next fiscal year consensus EPS 20.4x 8.4x 63.6x GRFS
Faster revenue growthRevenue growth, trailing twelve months +9.1% — +76.1% ARQT
More profitableNet margin, trailing twelve months 23.0% — 6.1% AMGN
Better return on capitalReturn on invested capital 14.3% — 10.6% AMGN
Less leveragedLower net debt / EBITDA 2.7x — — –
Higher dividend yieldTrailing dividend yield 0.02% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +52.4% -16.3% +58.2% ARQT
Better 5-year returnAnnualised price return, 5 years +16.6%/yr -9.9%/yr +8.6%/yr AMGN
Less volatileAnnualised volatility, 1 year 29.7% 32.4% 56.8% AMGN
Higher overall scoreMean of the five percentile scores vs peers 66/100 57/100 76/100 ARQT

Percentile Scorecard

AMGNGRFSARQT

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisAMGNGRFSARQT
Valuation 85 #94 of 626 99 #6 of 626 69 #192 of 626
Growth 61 #234 of 604 – 96 #28 of 604
Profitability 94 #33 of 555 – 89 #62 of 555
Financial Health 22 #512 of 658 14 #566 of 658 47 #349 of 658
Shareholder Returns 68 #117 of 368 56 #161 of 368 78 #83 of 368
Overall 66 57 76
  • AMGN ranked among 673 companies in Pharmaceuticals and Biotechnology
  • GRFS ranked among 673 companies in Pharmaceuticals and Biotechnology
  • ARQT ranked among 673 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodAMGNGRFSARQTSPY
1 month +7.2%+7.8%+18.2% -0.8%
3 months +18.2%+2.2%+14.3% +3.5%
6 months +30.7%-2.6%+35.8% +7.0%
Year to date +35.8%-15.3%+9.5% +12.2%
1 year +52.4%-16.3%+58.2% +13.0%
3 years +70.0%+1.0%+1,262.3% +86.3%
3 years, per year +19.4%+0.3%+139.0% +23.1%
5 years +115.2%-40.5%+50.7% +68.6%
5 years, per year +16.6%-9.9%+8.6% +11.0%
10 years +179.7%-46.6%— +258.0%
10 years, per year +10.8%-6.1%— +13.6%

Risk

MeasureAMGNGRFSARQTSPY
Volatility, 1Y 29.7%32.4%56.8% 12.7%
Downside volatility, 1Y 27.9%34.1%49.5% 12.7%
Beta vs S&P 500, 1Y 0.450.951.09 1.00
Return / volatility, 1Y 1.76-0.501.02 1.02
Max drawdown, 5Y -26.7%-58.9%-93.2% -25.4%
From 52-week high -0.6%-18.5%-3.1% -1.8%
52-week high $447.28$9.72$32.82 $779.14
52-week low $291.16$7.02$19.50 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleAMGNGRFSARQT
P/E now vs peer median 27.5xmedian 17.1x 11.9xmedian 17.1x 145.6xmedian 17.1x
P/S now vs peer median 6.3xmedian 8.8x 0.6xmedian 8.8x 8.6xmedian 8.8x
EV/EBITDA now vs peer median 17.6xmedian 17.1x —median 17.1x —median 17.1x
P/FCF now vs peer median 23.6xmedian 18.0x 7.6xmedian 18.0x 102.0xmedian 18.0x
P/B now vs peer median 20.6xmedian 2.1x 0.6xmedian 2.1x 18.1xmedian 2.1x
PEG now vs peer median 10.36median 0.31 —median 0.31 5.43median 0.31

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsAMGNGRFSARQT
Revenue $38.10B – $463.98M
Gross profit $26.48B – $422.89M
Operating income $11.43B – $34.25M
Net income $8.74B – $28.52M
Free cash flow $10.18B – $39.15M
R&D $7.63B – $91.04M
EPS (diluted) $16.07 – $0.21
Cash & equivalents $13.99B $969.15M –
Total debt $57.30B $44.00B $108.90M
Shares (diluted) 544.00M 681.57M 135.90M
Enterprise value $197.46B $1.86B $3.42B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricAMGNGRFSARQT
P/E 27.5x 11.9x 145.6x
P/FCF 23.6x 7.6x 102.0x
P/Operating cash flow 19.3x – 101.6x
P/S 6.3x 0.6x 8.6x
P/B 20.6x 0.6x 18.1x
P/Tangible book -27.3x 0.9x 19.3x
EV/EBITDA 17.6x – –
EV/EBIT 24.8x – 113.8x
EV/Revenue 7.4x – 8.4x
EV/FCF 27.9x – 99.6x
EV/Operating cash flow 22.7x – 99.2x
PEG (3Y EPS CAGR) 10.36 – 5.43

Growth

14 metrics
MetricAMGNGRFSARQT
Revenue growth (1Y) 9.1% – 76.1%
Revenue CAGR (3Y) 12.7% – 241.4%
Gross profit growth (1Y) 17.6% – 80.2%
Gross profit CAGR (3Y) 10.3% – 256.4%
Operating income growth (1Y) 39.5% – 139.9%
Operating income CAGR (3Y) 6.4% – 28.2%
Net income growth (1Y) 32.1% – 130.6%
Net income CAGR (3Y) 3.1% – 27.8%
EPS growth (1Y) 31.4% – 128.6%
EPS CAGR (3Y) 2.7% – 26.8%
Operating cash flow growth (1Y) 3.9% – 160.0%
Operating cash flow CAGR (3Y) 4.9% – 28.8%
Free cash flow growth (1Y) -4.1% – 159.0%
Free cash flow CAGR (3Y) 1.7% – 28.8%

Profitability

14 metrics
MetricAMGNGRFSARQT
Gross margin 69.5% – 91.1%
EBITDA margin 42.2% – –
Operating margin 30.0% – 7.4%
Pretax margin 27.0% – 6.3%
Net margin 23.0% – 6.1%
FCF margin 26.7% – 8.4%
Operating cash flow margin 32.8% – 8.5%
Return on equity 83.8% – 13.9%
Return on assets 9.3% – 6.0%
Return on invested capital 14.3% – 10.6%
Return on capital employed 16.7% – 10.9%
Asset turnover 0.4x – 1.0x
Cash conversion (OCF / net income) 1.4x – 1.4x
Stock comp / revenue 1.3% – 9.4%

Financial Health

11 metrics
MetricAMGNGRFSARQT
Debt / assets 59.9% 48.9% 22.3%
Debt / equity 4.9x 1.3x 0.5x
Net debt / EBITDA 2.7x – –
Debt / FCF 5.6x – 2.8x
Liabilities / assets 87.8% 61.4% 54.8%
Equity / assets 12.2% 38.6% 45.2%
Interest coverage 4.3x – 2.5x
Current ratio 1.4x 2.5x 2.9x
Quick ratio 0.9x 0.8x 2.2x
Cash ratio 0.5x 0.4x 1.3x
Altman Z-score 2.30 – 7.63

Shareholder Returns

7 metrics
MetricAMGNGRFSARQT
Dividend yield 2.2% 1.4% –
Net buyback yield – – -0.2%
Shareholder yield 2.2% 1.4% -0.2%
Payout ratio (earnings) 60.4% – –
Payout ratio (FCF) 51.9% – –
Dividend growth (1Y) 6.3% – –
Dividend CAGR (3Y) 6.7% – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusAMGNGRFSARQT
Forward P/E 20.4xFY2026 8.4xFY2026 63.6xFY2026
EPS, next fiscal year $21.81FY2026 $0.94FY2026 $0.50FY2026
EPS growth, next FY -0.1%FY2026 +10.6%FY2026 –
EPS growth, the year after +7.2% +26.6% +152.0%
Revenue, next fiscal year $41.51BFY2026 $8.88BFY2026 $565.04MFY2026
Revenue growth, next FY +12.9%FY2026 +0.0%FY2026 +50.2%FY2026
Revenue growth, the year after +2.3% +10.3% +17.0%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersAMGNGRFSARQT
Held by institutions 82.7% 21.0% 100.0%
Institutions holding 3,159 166 271
Change in shares held, QoQ +4.5% -0.5% -0.4%
Institutions buying 1,451 73 138
Institutions selling 1,217 65 98
Buyers to sellers 1.19 1.12 1.41

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

AMGNGRFSARQT
AMGN 1.00 0.24 0.21
GRFS 0.24 1.00 0.30
ARQT 0.21 0.30 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, AMGN, GRFS and ARQT?

Amgen (AMGN) is the largest by market capitalisation: Amgen (AMGN) $242.06B, Grifols (GRFS) $5.52B, Arcutis Biotherapeutics (ARQT) $4.13B.

Which stock is cheaper, AMGN, GRFS and ARQT?

Grifols (GRFS) trades on the lowest price-to-earnings ratio (Amgen (AMGN) 27.7x, Grifols (GRFS) 11.9x, Arcutis Biotherapeutics (ARQT) 145.0x). On next year's consensus earnings, Grifols (GRFS) is cheapest (Amgen (AMGN) 20.4x, Grifols (GRFS) 8.4x, Arcutis Biotherapeutics (ARQT) 63.6x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Arcutis Biotherapeutics (ARQT) grew revenue fastest over the trailing twelve months: Amgen (AMGN) +9.1%, Arcutis Biotherapeutics (ARQT) +76.1%.

Which company is more profitable?

Amgen (AMGN) has the highest net margin (Amgen (AMGN) 23.0%, Arcutis Biotherapeutics (ARQT) 6.1%). On return on invested capital, Amgen (AMGN) leads (Amgen (AMGN) 14.3%, Arcutis Biotherapeutics (ARQT) 10.6%).

Which stock has performed better?

Over the past year Arcutis Biotherapeutics (ARQT) returned the most: Amgen (AMGN) +52.4%, Grifols (GRFS) -16.3%, Arcutis Biotherapeutics (ARQT) +58.2%. Over five years, Amgen (AMGN) compounded fastest (Amgen (AMGN) +16.6%/yr, Grifols (GRFS) -9.9%/yr, Arcutis Biotherapeutics (ARQT) +8.6%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Amgen (AMGN) 0.02%, Grifols (GRFS) 0.00%, Arcutis Biotherapeutics (ARQT) 0.00%. Grifols (GRFS) and Arcutis Biotherapeutics (ARQT) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Amgen (AMGN) has been the steadiest (Amgen (AMGN) 29.7%, Grifols (GRFS) 32.4%, Arcutis Biotherapeutics (ARQT) 56.8%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, AMGN, GRFS and ARQT?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Amgen (AMGN) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.