AMGN vs ARQT vs ARGX Stock Comparison

Amgen, Arcutis Biotherapeutics and Argenx Se Prices as of Oct 28, 2026 Peers: Industry group
AMGN Amgen Inc
$451.83 +8.1% 1M +54.7% 1Y
Market cap
$244.26B
P/E
27.9x
Revenue (TTM)
$38.10B
Div. yield
2.20%
Biotechnology Healthcare
6 wins
ARGX Argenx Se
$891.76 -8.3% 1M +6.6% 1Y
Market cap
$55.19B
P/E
29.1x
Revenue (TTM)
$5.82B
Div. yield
–
Biotechnology Healthcare
3 wins

Head to Head

10 decided of 12

Amgen leads on 6 of the 12 questions below (Amgen 6, Argenx Se 3, Arcutis Biotherapeutics 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionAMGNARQTARGXLeader
Larger companyMarket capitalisation $244.26B $3.95B $55.19B AMGN
Cheaper on earningsLower P/E, profitable companies only 27.9x 143.9x 29.1x AMGN
Cheaper on forward earningsLower price / next fiscal year consensus EPS 20.7x 62.9x 29.1x AMGN
Faster revenue growthRevenue growth, trailing twelve months +9.1% +76.1% +61.5% ARQT
More profitableNet margin, trailing twelve months 23.0% 6.1% 32.3% ARGX
Better return on capitalReturn on invested capital 14.3% 10.6% — AMGN
Less leveragedLower net debt / EBITDA 2.7x — — –
Higher dividend yieldTrailing dividend yield 2.20% — — –
Better 1-year returnPrice return, last 12 months +54.7% +26.1% +6.6% AMGN
Better 5-year returnAnnualised price return, 5 years +16.9%/yr +8.2%/yr +24.2%/yr ARGX
Less volatileAnnualised volatility, 1 year 29.7% 51.3% 36.9% AMGN
Higher overall scoreMean of the five percentile scores vs peers 66/100 76/100 92/100 ARGX

Percentile Scorecard

AMGNARQTARGX

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisAMGNARQTARGX
Valuation 86 #91 of 625 70 #188 of 625 84 #101 of 625
Growth 62 #231 of 602 96 #28 of 602 94 #35 of 602
Profitability 95 #31 of 549 89 #60 of 549 98 #11 of 549
Financial Health 22 #510 of 654 47 #347 of 654 –
Shareholder Returns 68 #118 of 367 77 #87 of 367 –
Overall 66 76 92
  • AMGN ranked among 672 companies in Pharmaceuticals and Biotechnology
  • ARQT ranked among 672 companies in Pharmaceuticals and Biotechnology
  • ARGX ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodAMGNARQTARGXSPY
1 month +8.1%+15.1%-8.3% +0.9%
3 months +16.6%+12.9%+1.0% +5.9%
6 months +33.7%+40.6%+14.9% +8.5%
Year to date +38.0%+8.3%+6.0% +13.3%
1 year +54.7%+26.1%+6.6% +12.4%
3 years +72.7%+1,246.9%+93.9% +88.1%
3 years, per year +20.0%+138.1%+24.7% +23.5%
5 years +118.3%+48.5%+195.3% +68.2%
5 years, per year +16.9%+8.2%+24.2% +11.0%
10 years +211.2%—— +263.4%
10 years, per year +12.0%—— +13.8%

Risk

MeasureAMGNARQTARGXSPY
Volatility, 1Y 29.7%51.3%36.9% 12.7%
Downside volatility, 1Y 27.9%49.1%34.6% 12.7%
Beta vs S&P 500, 1Y 0.461.050.39 1.00
Return / volatility, 1Y 1.840.510.18 0.98
Max drawdown, 5Y -26.7%-93.2%-38.2% -25.4%
From 52-week high 0.0%-4.2%-15.8% -0.9%
52-week high $451.83$32.82$1,058.90 $779.14
52-week low $291.77$19.50$663.93 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleAMGNARQTARGX
P/E now vs peer median 27.9xmedian 17.4x 143.9xmedian 17.4x 29.1xmedian 17.4x
P/S now vs peer median 6.4xmedian 9.1x 8.5xmedian 9.1x 9.5xmedian 9.1x
EV/EBITDA now vs peer median 17.9xmedian 17.1x —median 17.1x —median 17.1x
P/FCF now vs peer median 24.0xmedian 19.0x 100.9xmedian 19.0x —median 19.0x
P/B now vs peer median 20.9xmedian 2.2x 17.9xmedian 2.2x —median 2.2x
PEG now vs peer median 10.53median 0.34 5.37median 0.34 0.28median 0.34

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsAMGNARQTARGX
Revenue $38.10B $463.98M $5.82B
Gross profit $26.48B $422.89M $5.24B
Operating income $11.43B $34.25M $1.74B
Net income $8.74B $28.52M $1.88B
Free cash flow $10.18B $39.15M –
R&D $7.63B $91.04M $1.80B
EPS (diluted) $16.07 $0.21 $28.43
Cash & equivalents $13.99B – –
Total debt $57.30B $108.90M –
Shares (diluted) 544.00M 135.90M 66.03M
Enterprise value $199.66B $3.23B $55.19B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricAMGNARQTARGX
P/E 27.9x 143.9x 29.1x
P/FCF 24.0x 100.9x –
P/Operating cash flow 19.6x 100.5x –
P/S 6.4x 8.5x 9.5x
P/B 20.9x 17.9x –
P/Tangible book -27.8x 19.1x –
EV/EBITDA 17.9x – –
EV/EBIT 25.2x 112.5x 31.7x
EV/Revenue 7.5x 8.3x 9.5x
EV/FCF 28.3x 98.4x –
EV/Operating cash flow 23.0x 98.1x –
PEG (3Y EPS CAGR) 10.53 5.37 0.28

Growth

14 metrics
MetricAMGNARQTARGX
Revenue growth (1Y) 9.1% 76.1% 61.5%
Revenue CAGR (3Y) 12.7% 241.4% 80.5%
Gross profit growth (1Y) 17.6% 80.2% 62.2%
Gross profit CAGR (3Y) 10.3% 256.4% 80.0%
Operating income growth (1Y) 39.5% 139.9% 120.6%
Operating income CAGR (3Y) 6.4% 28.2% 85.1%
Net income growth (1Y) 32.1% 130.6% 22.5%
Net income CAGR (3Y) 3.1% 27.8% 115.5%
EPS growth (1Y) 31.4% 128.6% 20.9%
EPS CAGR (3Y) 2.7% 26.8% 104.8%
Operating cash flow growth (1Y) 3.9% 160.0% –
Operating cash flow CAGR (3Y) 4.9% 28.8% –
Free cash flow growth (1Y) -4.1% 159.0% –
Free cash flow CAGR (3Y) 1.7% 28.8% –

Profitability

14 metrics
MetricAMGNARQTARGX
Gross margin 69.5% 91.1% 90.0%
EBITDA margin 42.2% – –
Operating margin 30.0% 7.4% 29.9%
Pretax margin 27.0% 6.3% 32.6%
Net margin 23.0% 6.1% 32.3%
FCF margin 26.7% 8.4% –
Operating cash flow margin 32.8% 8.5% –
Return on equity 83.8% 13.9% –
Return on assets 9.3% 6.0% –
Return on invested capital 14.3% 10.6% –
Return on capital employed 16.7% 10.9% –
Asset turnover 0.4x 1.0x –
Cash conversion (OCF / net income) 1.4x 1.4x –
Stock comp / revenue 1.3% 9.4% –

Financial Health

11 metrics
MetricAMGNARQTARGX
Debt / assets 59.9% 22.3% –
Debt / equity 4.9x 0.5x –
Net debt / EBITDA 2.7x – –
Debt / FCF 5.6x 2.8x –
Liabilities / assets 87.8% 54.8% –
Equity / assets 12.2% 45.2% –
Interest coverage 4.3x 2.5x 10,120x
Current ratio 1.4x 2.9x –
Quick ratio 0.9x 2.2x –
Cash ratio 0.5x 1.3x –
Altman Z-score 2.33 7.53 –

Shareholder Returns

7 metrics
MetricAMGNARQTARGX
Dividend yield 2.2% – –
Net buyback yield – -0.2% –
Shareholder yield 2.2% -0.2% –
Payout ratio (earnings) 60.4% – –
Payout ratio (FCF) 51.9% – –
Dividend growth (1Y) 6.3% – –
Dividend CAGR (3Y) 6.7% – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusAMGNARQTARGX
Forward P/E 20.7xFY2026 62.9xFY2026 29.1xFY2026
EPS, next fiscal year $21.81FY2026 $0.50FY2026 $30.63FY2026
EPS growth, next FY -0.1%FY2026 – +56.5%FY2026
EPS growth, the year after +7.2% +152.0% +26.9%
Revenue, next fiscal year $41.51BFY2026 $565.04MFY2026 $6.08BFY2026
Revenue growth, next FY +12.9%FY2026 +50.2%FY2026 +43.1%FY2026
Revenue growth, the year after +2.3% +17.0% +22.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersAMGNARQTARGX
Held by institutions 82.7% 100.0% 46.1%
Institutions holding 3,160 271 504
Change in shares held, QoQ +4.5% -0.4% -2.0%
Institutions buying 1,452 138 264
Institutions selling 1,217 98 160
Buyers to sellers 1.19 1.41 1.65

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

AMGNARQTARGX
AMGN 1.00 0.21 0.31
ARQT 0.21 1.00 0.17
ARGX 0.31 0.17 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, AMGN, ARQT and ARGX?

Amgen (AMGN) is the largest by market capitalisation: Amgen (AMGN) $244.26B, Arcutis Biotherapeutics (ARQT) $3.95B, Argenx Se (ARGX) $55.19B.

Which stock is cheaper, AMGN, ARQT and ARGX?

Amgen (AMGN) trades on the lowest price-to-earnings ratio (Amgen (AMGN) 27.9x, Arcutis Biotherapeutics (ARQT) 143.9x, Argenx Se (ARGX) 29.1x). On next year's consensus earnings, Amgen (AMGN) is cheapest (Amgen (AMGN) 20.7x, Arcutis Biotherapeutics (ARQT) 62.9x, Argenx Se (ARGX) 29.1x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Arcutis Biotherapeutics (ARQT) grew revenue fastest over the trailing twelve months: Amgen (AMGN) +9.1%, Arcutis Biotherapeutics (ARQT) +76.1%, Argenx Se (ARGX) +61.5%.

Which company is more profitable?

Argenx Se (ARGX) has the highest net margin (Amgen (AMGN) 23.0%, Arcutis Biotherapeutics (ARQT) 6.1%, Argenx Se (ARGX) 32.3%). On return on invested capital, Amgen (AMGN) leads (Amgen (AMGN) 14.3%, Arcutis Biotherapeutics (ARQT) 10.6%).

Which stock has performed better?

Over the past year Amgen (AMGN) returned the most: Amgen (AMGN) +54.7%, Arcutis Biotherapeutics (ARQT) +26.1%, Argenx Se (ARGX) +6.6%. Over five years, Argenx Se (ARGX) compounded fastest (Amgen (AMGN) +16.9%/yr, Arcutis Biotherapeutics (ARQT) +8.2%/yr, Argenx Se (ARGX) +24.2%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Amgen (AMGN) 2.20%. Arcutis Biotherapeutics (ARQT) and Argenx Se (ARGX) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Amgen (AMGN) has been the steadiest (Amgen (AMGN) 29.7%, Arcutis Biotherapeutics (ARQT) 51.3%, Argenx Se (ARGX) 36.9%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, AMGN, ARQT and ARGX?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Amgen (AMGN) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.