ALNY vs ARGX Stock Comparison

Alnylam Pharmaceuticals and Argenx Se Prices as of Oct 23, 2026 Peers: Industry group
ARGX Argenx Se
$873.71 -7.6% 1M +7.6% 1Y
Market cap
$53.25B
P/E
28.4x
Revenue (TTM)
$5.82B
Div. yield
–
Biotechnology Healthcare
8 wins

Head to Head

9 decided of 12

Argenx Se leads on 8 of the 12 questions below (Argenx Se 8, Alnylam Pharmaceuticals 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionALNYARGXLeader
Larger companyMarket capitalisation $30.46B $53.25B ARGX
Cheaper on earningsLower P/E, profitable companies only 41.6x 28.4x ARGX
Cheaper on forward earningsLower price / next fiscal year consensus EPS 32.4x 28.0x ARGX
Faster revenue growthRevenue growth, trailing twelve months +90.1% +61.5% ALNY
More profitableNet margin, trailing twelve months 15.3% 32.3% ARGX
Better return on capitalReturn on invested capital — — –
Less leveragedLower net debt / EBITDA — — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -51.7% +7.6% ARGX
Better 5-year returnAnnualised price return, 5 years +2.4%/yr +24.4%/yr ARGX
Less volatileAnnualised volatility, 1 year 51.3% 36.9% ARGX
Higher overall scoreMean of the five percentile scores vs peers 77/100 92/100 ARGX

Percentile Scorecard

ALNYARGX

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisALNYARGX
Valuation 81 #122 of 624 84 #99 of 624
Growth 98 #12 of 603 95 #34 of 603
Profitability 93 #40 of 555 98 #10 of 555
Financial Health 45 #359 of 657 –
Shareholder Returns 67 #123 of 370 –
Overall 77 92
  • ALNY ranked among 671 companies in Pharmaceuticals and Biotechnology
  • ARGX ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodALNYARGXSPY
1 month -9.1%-7.6% -1.0%
3 months -17.6%-4.8% +2.9%
6 months -26.7%+12.0% +6.4%
Year to date -43.7%+3.9% +11.4%
1 year -51.7%+7.6% +13.1%
3 years +36.6%+81.6% +79.4%
3 years, per year +11.0%+22.0% +21.5%
5 years +12.8%+198.0% +67.7%
5 years, per year +2.4%+24.4% +10.9%
10 years +510.9%— +255.2%
10 years, per year +19.8%— +13.5%

Risk

MeasureALNYARGXSPY
Volatility, 1Y 51.3%36.9% 12.7%
Downside volatility, 1Y 62.6%34.8% 12.7%
Beta vs S&P 500, 1Y 0.360.40 1.00
Return / volatility, 1Y -1.010.21 1.03
Max drawdown, 5Y -58.2%-38.2% -25.4%
From 52-week high -53.5%-17.5% -2.5%
52-week high $481.59$1,058.90 $779.14
52-week low $205.48$663.93 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleALNYARGX
P/E now vs peer median 40.8xmedian 17.2x 28.5xmedian 17.2x
P/S now vs peer median 6.2xmedian 8.8x 9.3xmedian 8.8x
EV/EBITDA now vs peer median 25.3xmedian 16.0x —median 16.0x
P/FCF now vs peer median 36.5xmedian 17.8x —median 17.8x
P/B now vs peer median 22.1xmedian 2.1x —median 2.1x
PEG now vs peer median 1.08median 0.32 0.27median 0.32

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsALNYARGX
Revenue $4.80B $5.82B
Gross profit $3.83B $5.24B
Operating income $999.78M $1.74B
Net income $733.11M $1.88B
Free cash flow $819.87M –
R&D $1.51B $1.80B
EPS (diluted) $5.30 $28.43
Cash & equivalents $1.71B –
Shares (diluted) 138.28M 66.03M
Enterprise value $18.51B $53.25B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricALNYARGX
P/E 40.8x 28.5x
P/FCF 36.5x –
P/Operating cash flow 32.9x –
P/S 6.2x 9.3x
P/B 22.1x –
P/Tangible book 22.1x –
EV/EBITDA 25.3x –
EV/EBIT 26.7x 31.1x
EV/Revenue 5.5x 9.3x
EV/FCF 32.5x –
EV/Operating cash flow 29.2x –
PEG (3Y EPS CAGR) 1.08 0.27

Growth

14 metrics
MetricALNYARGX
Revenue growth (1Y) 90.1% 61.5%
Revenue CAGR (3Y) 57.2% 80.5%
Gross profit growth (1Y) 79.7% 62.2%
Gross profit CAGR (3Y) 54.6% 80.0%
Operating income growth (1Y) 654.9% 120.6%
Operating income CAGR (3Y) 47.5% 85.1%
Net income growth (1Y) 356.5% 22.5%
Net income CAGR (3Y) 39.1% 115.5%
EPS growth (1Y) 342.3% 20.9%
EPS CAGR (3Y) 37.9% 104.8%
Operating cash flow growth (1Y) 2,299% –
Operating cash flow CAGR (3Y) 57.8% –
Free cash flow growth (1Y) 1,151% –
Free cash flow CAGR (3Y) 52.1% –

Profitability

14 metrics
MetricALNYARGX
Gross margin 79.8% 90.0%
EBITDA margin 22.0% –
Operating margin 20.8% 29.9%
Pretax margin 16.0% 32.6%
Net margin 15.3% 32.3%
FCF margin 17.1% –
Operating cash flow margin 19.0% –
Return on equity 63.8% –
Return on assets 14.5% –
Return on invested capital – –
Return on capital employed 26.1% –
Asset turnover 0.9x –
Cash conversion (OCF / net income) 1.2x –
Stock comp / revenue 7.0% –

Financial Health

11 metrics
MetricALNYARGX
Debt / assets – –
Debt / equity – –
Net debt / EBITDA – –
Debt / FCF – –
Liabilities / assets 75.6% –
Equity / assets 24.4% –
Interest coverage 3.8x 10,120x
Current ratio 3.1x –
Quick ratio 2.8x –
Cash ratio 2.2x –
Altman Z-score 4.81 –

Shareholder Returns

7 metrics
MetricALNYARGX
Dividend yield – –
Net buyback yield -0.6% –
Shareholder yield -0.6% –
Payout ratio (earnings) – –
Payout ratio (FCF) – –
Dividend growth (1Y) – –
Dividend CAGR (3Y) – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusALNYARGX
Forward P/E 32.4xFY2026 28.0xFY2026
EPS, next fiscal year $6.92FY2026 $31.22FY2026
EPS growth, next FY +197.0%FY2026 +59.5%FY2026
EPS growth, the year after +34.0% +29.0%
Revenue, next fiscal year $5.68BFY2026 $5.97BFY2026
Revenue growth, next FY +53.1%FY2026 +40.4%FY2026
Revenue growth, the year after +27.4% +21.7%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersALNYARGX
Held by institutions 99.7% 46.1%
Institutions holding 786 504
Change in shares held, QoQ +3.8% -2.0%
Institutions buying 412 264
Institutions selling 277 160
Buyers to sellers 1.49 1.65

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ALNYARGX
ALNY 1.00 0.18
ARGX 0.18 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ALNY and ARGX?

Argenx Se (ARGX) is the largest by market capitalisation: Alnylam Pharmaceuticals (ALNY) $30.46B, Argenx Se (ARGX) $53.25B.

Which stock is cheaper, ALNY and ARGX?

Argenx Se (ARGX) trades on the lowest price-to-earnings ratio (Alnylam Pharmaceuticals (ALNY) 41.6x, Argenx Se (ARGX) 28.4x). On next year's consensus earnings, Argenx Se (ARGX) is cheapest (Alnylam Pharmaceuticals (ALNY) 32.4x, Argenx Se (ARGX) 28.0x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Alnylam Pharmaceuticals (ALNY) grew revenue fastest over the trailing twelve months: Alnylam Pharmaceuticals (ALNY) +90.1%, Argenx Se (ARGX) +61.5%.

Which company is more profitable?

Argenx Se (ARGX) has the highest net margin (Alnylam Pharmaceuticals (ALNY) 15.3%, Argenx Se (ARGX) 32.3%).

Which stock has performed better?

Over the past year Argenx Se (ARGX) returned the most: Alnylam Pharmaceuticals (ALNY) -51.7%, Argenx Se (ARGX) +7.6%. Over five years, Argenx Se (ARGX) compounded fastest (Alnylam Pharmaceuticals (ALNY) +2.4%/yr, Argenx Se (ARGX) +24.4%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Argenx Se (ARGX) has been the steadiest (Alnylam Pharmaceuticals (ALNY) 51.3%, Argenx Se (ARGX) 36.9%). Volatility measures how widely the price swings, not the risk of the business.

Do ALNY and ARGX move together?

Their daily returns over the past year have a correlation of 0.18, a weak relationship. Holding both diversifies more than two closely linked stocks would.

Which is the better stock, ALNY and ARGX?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Argenx Se (ARGX) leads on 8. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.