ALLO vs IOVA vs MESO Stock Comparison

Allogene Therapeutics, Iovance Biotherapeutics and Mesoblast Prices as of Oct 27, 2026 Peers: Industry group
MESO Mesoblast Ltd
$13.18 -12.8% 1M -21.1% 1Y
Market cap
$1.71B
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
2 wins

Head to Head

6 decided of 12

Iovance Biotherapeutics leads on 4 of the 12 questions below (Iovance Biotherapeutics 4, Mesoblast 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionALLOIOVAMESOLeader
Larger companyMarket capitalisation $424.77M $6.60B $1.71B IOVA
Cheaper on earningsLower P/E, profitable companies only -2.4x -22.7x -29.7x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — — –
Faster revenue growthRevenue growth, trailing twelve months — +34.5% — –
More profitableNet margin, trailing twelve months -3,566.7% -89.1% — IOVA
Better return on capitalReturn on invested capital — — — –
Less leveragedLower net debt / EBITDA — — — –
Higher dividend yieldTrailing dividend yield — — — –
Better 1-year returnPrice return, last 12 months 0.0% +531.2% -21.1% IOVA
Better 5-year returnAnnualised price return, 5 years -41.0%/yr -10.4%/yr +1.9%/yr MESO
Less volatileAnnualised volatility, 1 year 82.7% 99.2% 54.8% MESO
Higher overall scoreMean of the five percentile scores vs peers 55/100 64/100 — IOVA

Percentile Scorecard

ALLOIOVAMESO

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisALLOIOVAMESO
Valuation 18 #512 of 625 67 #209 of 625 70 #189 of 625
Growth 91 #58 of 602 81 #114 of 602 –
Profitability 24 #417 of 551 62 #210 of 551 –
Financial Health 63 #244 of 656 64 #238 of 656 44 #365 of 656
Shareholder Returns 79 #76 of 365 44 #205 of 365 –
Overall 55 64 –
  • ALLO ranked among 672 companies in Pharmaceuticals and Biotechnology
  • IOVA ranked among 672 companies in Pharmaceuticals and Biotechnology
  • MESO ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodALLOIOVAMESOSPY
1 month -25.5%+32.5%-12.8% -0.2%
3 months -25.9%+210.2%-8.8% +3.9%
6 months -43.8%+331.4%-13.4% +8.2%
Year to date -10.2%+434.1%-26.9% +12.9%
1 year 0.0%+531.2%-21.1% +12.3%
3 years -51.4%+316.6%+463.2% +87.4%
3 years, per year -21.4%+61.0%+78.0% +23.3%
5 years -92.8%-42.3%+9.7% +67.9%
5 years, per year -41.0%-10.4%+1.9% +10.9%
10 years —+143.0%+56.2% +261.1%
10 years, per year —+9.3%+4.6% +13.7%

Risk

MeasureALLOIOVAMESOSPY
Volatility, 1Y 82.7%99.2%54.8% 12.7%
Downside volatility, 1Y 82.1%71.2%54.9% 12.7%
Beta vs S&P 500, 1Y 1.831.281.52 1.00
Return / volatility, 1Y 0.005.36-0.39 0.97
Max drawdown, 5Y -95.3%-93.4%-87.9% -25.4%
From 52-week high -59.8%-1.9%-37.1% -1.2%
52-week high $3.06$14.86$20.96 $779.14
52-week low $1.05$1.81$11.95 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleALLOIOVAMESO
P/E now vs peer median -2.4xmedian 17.2x -22.7xmedian 17.2x -29.7xmedian 17.2x
P/S now vs peer median 91.5xmedian 9.0x 20.3xmedian 9.0x 14.2xmedian 9.0x
EV/EBITDA now vs peer median -0.5xmedian 16.3x -23.9xmedian 16.3x —median 16.3x
P/FCF now vs peer median -3.7xmedian 18.7x -22.3xmedian 18.7x -38.2xmedian 18.7x
P/B now vs peer median 1.0xmedian 2.2x 9.0xmedian 2.2x 3.0xmedian 2.2x
PEG now vs peer median -0.06median 0.33 -0.76median 0.33 —median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsALLOIOVAMESO
Revenue $4.64M $324.97M –
Gross profit – $157.29M –
Operating income -$180.32M -$301.31M –
Net income -$165.49M -$289.51M –
Free cash flow -$115.53M -$296.40M –
R&D $122.52M $267.72M –
EPS (diluted) $-0.50 $-0.64 –
Cash & equivalents $38.63M $110.80M $102.91M
Total debt – – $119.24M
Shares (diluted) 328.93M 450.19M 129.49M
Enterprise value -$677.12M $5.40B $1.27B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricALLOIOVAMESO
P/E -2.4x -22.7x -29.7x
P/FCF -3.7x -22.3x -38.2x
P/Operating cash flow -4.2x -25.0x –
P/S 91.5x 20.3x 14.2x
P/B 1.0x 9.0x 3.0x
P/Tangible book 1.0x 14.0x 3.0x
EV/EBITDA -0.5x -23.9x –
EV/EBIT -0.5x -20.9x –
EV/Revenue 19.9x 19.4x –
EV/FCF -0.8x -21.3x –
EV/Operating cash flow -0.9x -23.9x –
PEG (3Y EPS CAGR) -0.06 -0.76 –

Growth

14 metrics
MetricALLOIOVAMESO
Revenue growth (1Y) – 34.5% –
Revenue CAGR (3Y) 253.5% 1,009% –
Gross profit growth (1Y) – 95.1% –
Gross profit CAGR (3Y) – – –
Operating income growth (1Y) 29.1% 26.6% –
Operating income CAGR (3Y) 20.5% 11.1% –
Net income growth (1Y) 30.1% 25.8% –
Net income CAGR (3Y) 22.9% 11.6% –
EPS growth (1Y) 53.5% 44.8% –
EPS CAGR (3Y) 41.1% 29.9% –
Operating cash flow growth (1Y) 40.8% 12.9% –
Operating cash flow CAGR (3Y) 24.6% 7.6% –
Free cash flow growth (1Y) 38.0% 8.4% –
Free cash flow CAGR (3Y) 23.0% 5.8% –

Profitability

14 metrics
MetricALLOIOVAMESO
Gross margin – 48.4% –
EBITDA margin -3,634% -81.4% –
Operating margin -3,886% -92.7% –
Pretax margin -3,574% -90.4% –
Net margin -3,567% -89.1% –
FCF margin -2,490% -91.2% –
Operating cash flow margin -2,203% -81.3% –
Return on equity -46.4% -39.7% –
Return on assets -35.1% -31.4% –
Return on invested capital – – –
Return on capital employed -40.9% -37.0% –
Asset turnover 0.0x 0.4x –
Cash conversion (OCF / net income) 0.6x 0.9x –
Stock comp / revenue 808.0% 14.4% –

Financial Health

11 metrics
MetricALLOIOVAMESO
Debt / assets – – 15.4%
Debt / equity – – 0.2x
Net debt / EBITDA – – –
Debt / FCF – – –
Liabilities / assets 20.7% 19.6% 26.5%
Equity / assets 79.3% 80.4% 73.5%
Interest coverage -138.7x – –
Current ratio 10.7x 4.3x 2.4x
Quick ratio 10.5x 3.7x 2.0x
Cash ratio 10.5x 2.8x 1.3x
Altman Z-score -3.50 17.38 –

Shareholder Returns

7 metrics
MetricALLOIOVAMESO
Dividend yield – – –
Net buyback yield -0.2% -4.5% –
Shareholder yield -0.2% -4.5% –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusALLOIOVAMESO
EPS, next fiscal year $-0.63FY2026 $-0.47FY2026 $-0.15FY2027
Revenue, next fiscal year $4.07MFY2026 $434.71MFY2026 $188.99MFY2027
Revenue growth, next FY – +65.0%FY2026 +57.2%FY2027
Revenue growth, the year after +207.8% +33.0% +110.3%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersALLOIOVAMESO
Held by institutions 90.5% 63.3% 3.0%
Institutions holding 209 292 73
Change in shares held, QoQ +69.8% +6.5% +17.7%
Institutions buying 133 174 34
Institutions selling 48 66 20
Buyers to sellers 2.77 2.64 1.70

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ALLOIOVAMESO
ALLO 1.00 0.21 0.19
IOVA 0.21 1.00 0.29
MESO 0.19 0.29 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ALLO, IOVA and MESO?

Iovance Biotherapeutics (IOVA) is the largest by market capitalisation: Allogene Therapeutics (ALLO) $424.77M, Iovance Biotherapeutics (IOVA) $6.60B, Mesoblast (MESO) $1.71B.

Which company is more profitable?

Iovance Biotherapeutics (IOVA) has the highest net margin (Allogene Therapeutics (ALLO) -3,566.7%, Iovance Biotherapeutics (IOVA) -89.1%).

Which stock has performed better?

Over the past year Iovance Biotherapeutics (IOVA) returned the most: Allogene Therapeutics (ALLO) 0.0%, Iovance Biotherapeutics (IOVA) +531.2%, Mesoblast (MESO) -21.1%. Over five years, Mesoblast (MESO) compounded fastest (Allogene Therapeutics (ALLO) -41.0%/yr, Iovance Biotherapeutics (IOVA) -10.4%/yr, Mesoblast (MESO) +1.9%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Mesoblast (MESO) has been the steadiest (Allogene Therapeutics (ALLO) 82.7%, Iovance Biotherapeutics (IOVA) 99.2%, Mesoblast (MESO) 54.8%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ALLO, IOVA and MESO?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Iovance Biotherapeutics (IOVA) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.