AIFF vs HTFL vs QDEL Stock Comparison

Firefly Neuroscience, Heartflow and QuidelOrtho Prices as of Oct 29, 2026 Peers: Industry group
HTFL Heartflow, Inc.
$60.53 +21.5% 1M +61.3% 1Y
Market cap
$5.01B
P/E
–
Revenue (TTM)
$202.91M
Div. yield
–
Diagnostic Equipment Healthcare
5 wins
QDEL QuidelOrtho Corp
$13.76 +29.8% 1M -50.8% 1Y
Market cap
$862.63M
P/E
–
Revenue (TTM)
-$211.90M
Div. yield
–
Diagnostic Equipment Healthcare
1 win

Head to Head

7 decided of 12

Heartflow leads on 5 of the 12 questions below (Heartflow 5, Firefly Neuroscience 1, QuidelOrtho 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionAIFFHTFLQDELLeader
Larger companyMarket capitalisation $21.61M $5.01B $862.63M HTFL
Cheaper on earningsLower P/E, profitable companies only -2.3x -50.0x -0.8x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — 18.3x –
Faster revenue growthRevenue growth, trailing twelve months +320.3% +42.5% -30.8% AIFF
More profitableNet margin, trailing twelve months -524.5% -49.4% — HTFL
Better return on capitalReturn on invested capital — — — –
Less leveragedLower net debt / EBITDA — — — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -46.4% +61.3% -50.8% HTFL
Better 5-year returnAnnualised price return, 5 years -60.3%/yr — -36.5%/yr QDEL
Less volatileAnnualised volatility, 1 year 159.8% 76.8% 92.9% HTFL
Higher overall scoreMean of the five percentile scores vs peers 38/100 56/100 22/100 HTFL

Percentile Scorecard

AIFFHTFLQDEL

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisAIFFHTFLQDEL
Valuation 15 #194 of 227 9 #207 of 227 47 #120 of 227
Growth 60 #87 of 218 74 #57 of 218 1 #216 of 218
Profitability 15 #172 of 202 49 #103 of 202 –
Financial Health 80 #48 of 233 91 #22 of 233 10 #209 of 233
Shareholder Returns 21 #103 of 130 – 29 #93 of 130
Overall 38 56 22
  • AIFF ranked among 247 companies in Medical Devices and Diagnostics
  • HTFL ranked among 247 companies in Medical Devices and Diagnostics
  • QDEL ranked among 247 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodAIFFHTFLQDELSPY
1 month -36.4%+21.5%+29.8% +0.7%
3 months +2.0%+134.3%-17.0% +3.7%
6 months -54.0%+103.4%+11.9% +7.1%
Year to date +17.0%+107.7%-51.8% +12.8%
1 year -46.4%+61.3%-50.8% +11.9%
3 years -81.5%—-77.1% +85.2%
3 years, per year -43.1%—-38.9% +22.8%
5 years -99.0%—-89.6% +67.6%
5 years, per year -60.3%—-36.5% +10.9%
10 years -77.1%—-29.3% +262.0%
10 years, per year -13.7%—-3.4% +13.7%

Risk

MeasureAIFFHTFLQDELSPY
Volatility, 1Y 159.8%76.8%92.9% 12.7%
Downside volatility, 1Y 108.9%78.1%100.7% 12.6%
Beta vs S&P 500, 1Y 1.541.892.62 1.00
Return / volatility, 1Y -0.290.80-0.55 0.94
Max drawdown, 5Y -99.6%-48.7%-94.3% -25.4%
From 52-week high -65.9%0.0%-61.1% -1.2%
52-week high $3.02$60.53$35.38 $779.14
52-week low $0.64$20.49$9.96 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleAIFFHTFLQDEL
P/E now vs peer median -2.2xmedian 28.7x -52.2xmedian 28.7x -0.9xmedian 28.7x
P/S now vs peer median 11.8xmedian 3.0x 25.9xmedian 3.0x -4.4xmedian 3.0x
EV/EBITDA now vs peer median -1.3xmedian 17.8x —median 17.8x —median 17.8x
P/FCF now vs peer median -2.9xmedian 26.4x —median 26.4x -4.4xmedian 26.4x
P/B now vs peer median 1.4xmedian 2.4x 18.8xmedian 2.4x 0.5xmedian 2.4x
PEG now vs peer median -0.03median 0.99 —median 0.99 0.01median 0.99

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsAIFFHTFLQDEL
Revenue $1.80M $202.91M -$211.90M
Gross profit $802.00K $160.45M –
Operating income -$9.14M -$64.46M –
Net income -$9.11M -$100.19M -$1.05B
Free cash flow -$7.20M – -$211.20M
R&D $1.78M $77.26M –
EPS (diluted) $-0.70 $-1.16 $-15.35
Cash & equivalents $9.23M $34.36M $123.40M
Total debt – – $2.89B
Shares (diluted) 13.50M 86.40M 68.30M
Enterprise value $2.18M $4.76B $330.93M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricAIFFHTFLQDEL
P/E -2.2x -52.2x -0.9x
P/FCF -2.9x – -4.4x
P/Operating cash flow -3.0x – -16.4x
P/S 11.8x 25.9x -4.4x
P/B 1.4x 18.8x 0.5x
P/Tangible book 1.5x 18.8x -1.0x
EV/EBITDA -1.3x – –
EV/EBIT -1.3x -77.6x –
EV/Revenue 6.7x 24.7x -17.5x
EV/FCF -1.7x – -17.6x
EV/Operating cash flow -1.7x – -64.8x
PEG (3Y EPS CAGR) -0.03 – 0.01

Growth

14 metrics
MetricAIFFHTFLQDEL
Revenue growth (1Y) 320.3% 42.5% -30.8%
Revenue CAGR (3Y) -40.3% – -27.0%
Gross profit growth (1Y) 99.0% 48.8% –
Gross profit CAGR (3Y) -32.6% – –
Operating income growth (1Y) 19.8% -9.5% –
Operating income CAGR (3Y) -52.0% – –
Net income growth (1Y) 60.1% -18.3% -124.8%
Net income CAGR (3Y) 15.8% – -107.7%
EPS growth (1Y) 81.8% 91.4% -122.8%
EPS CAGR (3Y) 69.0% – -106.5%
Operating cash flow growth (1Y) 19.1% – -128.5%
Operating cash flow CAGR (3Y) -8.4% – -27.1%
Free cash flow growth (1Y) 17.6% – -1,725%
Free cash flow CAGR (3Y) -6.3% – -30.1%

Profitability

14 metrics
MetricAIFFHTFLQDEL
Gross margin 44.6% 79.1% –
EBITDA margin -496.9% – –
Operating margin -508.1% -31.8% –
Pretax margin -506.2% -49.4% –
Net margin -524.5% -49.4% –
FCF margin -400.2% – –
Operating cash flow margin -388.6% – 27.0%
Return on equity -78.8% -34.5% –
Return on assets -65.8% -28.5% –
Return on invested capital – – –
Return on capital employed -77.9% -20.9% –
Asset turnover 0.1x 0.6x 0.0x
Cash conversion (OCF / net income) 0.8x – 0.1x
Stock comp / revenue 36.4% 9.6% -20.9%

Financial Health

11 metrics
MetricAIFFHTFLQDEL
Debt / assets – – 50.6%
Debt / equity – – 1.6x
Net debt / EBITDA – – –
Debt / FCF – – -13.7x
Liabilities / assets 12.6% 18.8% 68.9%
Equity / assets 87.4% 81.2% 31.1%
Interest coverage – – –
Current ratio 4.9x 5.1x 1.4x
Quick ratio 4.5x 6.6x 0.5x
Cash ratio 4.4x 5.6x 0.1x
Altman Z-score -4.72 44.65 –

Shareholder Returns

7 metrics
MetricAIFFHTFLQDEL
Dividend yield – – –
Net buyback yield -1.9% – -0.6%
Shareholder yield -1.9% – -0.6%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusAIFFHTFLQDEL
Forward P/E – – 18.3xFY2026
EPS, next fiscal year – $-0.43FY2026 $0.75FY2026
EPS growth, next FY – – -64.6%FY2026
EPS growth, the year after – – +101.3%
Revenue, next fiscal year – $261.38MFY2026 $2.67BFY2026
Revenue growth, next FY – +48.5%FY2026 -2.0%FY2026
Revenue growth, the year after – +20.6% +0.2%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersAIFFHTFLQDEL
Held by institutions 7.9% 100.0% 100.0%
Institutions holding 23 193 243
Change in shares held, QoQ +34.3% +133.0% +2.9%
Institutions buying 10 140 143
Institutions selling 6 38 65
Buyers to sellers 1.67 3.68 2.20

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

AIFFHTFLQDEL
AIFF 1.00 0.04 0.08
HTFL 0.04 1.00 0.16
QDEL 0.08 0.16 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, AIFF, HTFL and QDEL?

Heartflow (HTFL) is the largest by market capitalisation: Firefly Neuroscience (AIFF) $21.61M, Heartflow (HTFL) $5.01B, QuidelOrtho (QDEL) $862.63M.

Which company is growing faster?

Firefly Neuroscience (AIFF) grew revenue fastest over the trailing twelve months: Firefly Neuroscience (AIFF) +320.3%, Heartflow (HTFL) +42.5%, QuidelOrtho (QDEL) -30.8%.

Which company is more profitable?

Heartflow (HTFL) has the highest net margin (Firefly Neuroscience (AIFF) -524.5%, Heartflow (HTFL) -49.4%).

Which stock has performed better?

Over the past year Heartflow (HTFL) returned the most: Firefly Neuroscience (AIFF) -46.4%, Heartflow (HTFL) +61.3%, QuidelOrtho (QDEL) -50.8%. Over five years, QuidelOrtho (QDEL) compounded fastest (Firefly Neuroscience (AIFF) -60.3%/yr, QuidelOrtho (QDEL) -36.5%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Heartflow (HTFL) has been the steadiest (Firefly Neuroscience (AIFF) 159.8%, Heartflow (HTFL) 76.8%, QuidelOrtho (QDEL) 92.9%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, AIFF, HTFL and QDEL?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Heartflow (HTFL) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.