ADPT vs TEM vs GRAL Stock Comparison

Adaptive Biotechnologies, Tempus AI and Grail Prices as of Oct 27, 2026 Peers: Industry group
TEM Tempus AI, Inc.
$72.15 -15.1% 1M -21.2% 1Y
Market cap
$12.64B
P/E
–
Revenue (TTM)
$1.43B
Div. yield
–
Diagnostic Labs Healthcare
3 wins
GRAL GRAIL, Inc.
$150.61 +18.7% 1M +77.2% 1Y
Market cap
$6.73B
P/E
–
Revenue (TTM)
$157.21M
Div. yield
–
Diagnostic Labs Healthcare
2 wins

Head to Head

6 decided of 12

Tempus AI leads on 3 of the 12 questions below (Tempus AI 3, Grail 2, Adaptive Biotechnologies 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionADPTTEMGRALLeader
Larger companyMarket capitalisation $4.40B $12.64B $6.73B TEM
Cheaper on earningsLower P/E, profitable companies only -69.2x -51.0x -16.6x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — — –
Faster revenue growthRevenue growth, trailing twelve months +50.1% +50.4% +17.1% TEM
More profitableNet margin, trailing twelve months -20.7% -17.8% -249.1% TEM
Better return on capitalReturn on invested capital — -52.0% — –
Less leveragedLower net debt / EBITDA — — — –
Higher dividend yieldTrailing dividend yield — 0.00% — –
Better 1-year returnPrice return, last 12 months +61.6% -21.2% +77.2% GRAL
Better 5-year returnAnnualised price return, 5 years -4.4%/yr — — –
Less volatileAnnualised volatility, 1 year 67.8% 76.8% 111.3% ADPT
Higher overall scoreMean of the five percentile scores vs peers 43/100 26/100 43/100 GRAL

Percentile Scorecard

ADPTTEMGRAL

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisADPTTEMGRAL
Valuation 15 #78 of 92 9 #84 of 92 8 #85 of 92
Growth 85 #14 of 87 27 #64 of 87 58 #37 of 87
Profitability 24 #66 of 86 11 #77 of 86 6 #81 of 86
Financial Health 66 #34 of 97 57 #42 of 97 99 #2 of 97
Shareholder Returns 24 #43 of 56 – –
Overall 43 26 43
  • ADPT ranked among 102 companies in Healthcare Providers
  • TEM ranked among 102 companies in Healthcare Providers
  • GRAL ranked among 102 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodADPTTEMGRALSPY
1 month -6.0%-15.1%+18.7% -0.2%
3 months +22.8%+68.2%+133.8% +3.9%
6 months +97.0%+41.2%+188.5% +8.2%
Year to date +70.3%+22.2%+76.0% +12.9%
1 year +61.6%-21.2%+77.2% +12.3%
3 years +550.8%—— +87.4%
3 years, per year +86.8%—— +23.3%
5 years -19.9%—— +67.9%
5 years, per year -4.4%—— +10.9%

Risk

MeasureADPTTEMGRALSPY
Volatility, 1Y 67.8%76.8%111.3% 12.7%
Downside volatility, 1Y 63.7%66.8%126.1% 12.7%
Beta vs S&P 500, 1Y 1.672.562.69 1.00
Return / volatility, 1Y 0.91-0.280.69 0.97
Max drawdown, 5Y -93.6%-59.8%-62.9% -25.4%
From 52-week high -7.3%-21.2%-2.3% -1.2%
52-week high $29.84$91.58$154.08 $779.14
52-week low $12.41$41.55$43.03 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleADPTTEMGRAL
P/E now vs peer median -69.2xmedian 24.6x -51.0xmedian 24.6x -16.6xmedian 24.6x
P/S now vs peer median 14.3xmedian 1.6x 8.8xmedian 1.6x 42.8xmedian 1.6x
EV/EBITDA now vs peer median -188.5xmedian 14.6x —median 14.6x -14.5xmedian 14.6x
P/FCF now vs peer median -183.1xmedian 21.6x -48.0xmedian 21.6x -22.7xmedian 21.6x
P/B now vs peer median 29.2xmedian 3.2x 28.4xmedian 3.2x 2.6xmedian 3.2x
PEG now vs peer median -2.10median 0.66 —median 0.66 —median 0.66

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsADPTTEMGRAL
Revenue $308.08M $1.43B $157.21M
Gross profit $232.83M $916.19M $75.51M
Operating income -$37.46M -$283.03M -$559.25M
Net income -$63.99M -$254.43M -$391.59M
Free cash flow -$24.03M -$263.22M -$296.16M
R&D $88.21M $196.31M $190.72M
EPS (diluted) $-0.40 $-1.39 $-9.08
Cash & equivalents $169.87M $599.61M $55.65M
Shares (diluted) 159.86M 182.40M 43.11M
Enterprise value $3.40B $9.67B $3.60B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricADPTTEMGRAL
P/E -69.2x -51.0x -16.6x
P/FCF -183.1x -48.0x -22.7x
P/Operating cash flow -209.4x -53.2x -22.8x
P/S 14.3x 8.8x 42.8x
P/B 29.2x 28.4x 2.6x
P/Tangible book 29.4x 95.4x 8.8x
EV/EBITDA -188.5x – -14.5x
EV/EBIT -108.3x -41.8x -10.5x
EV/Revenue 13.2x 8.3x 37.3x
EV/FCF -168.7x -44.9x -19.8x
EV/Operating cash flow -193.0x -49.8x -19.9x
PEG (3Y EPS CAGR) -2.10 – –

Growth

14 metrics
MetricADPTTEMGRAL
Revenue growth (1Y) 50.1% 50.4% 17.1%
Revenue CAGR (3Y) 17.6% – –
Gross profit growth (1Y) 71.8% 58.5% 30.2%
Gross profit CAGR (3Y) 24.2% – –
Operating income growth (1Y) 69.1% -20.6% 11.6%
Operating income CAGR (3Y) 41.8% – –
Net income growth (1Y) 47.2% -27.4% 11.6%
Net income CAGR (3Y) 30.5% – –
EPS growth (1Y) 49.9% -21.1% 26.6%
EPS CAGR (3Y) 32.9% – –
Operating cash flow growth (1Y) 73.9% -356.2% 20.3%
Operating cash flow CAGR (3Y) 48.6% – –
Free cash flow growth (1Y) 71.0% -278.0% 20.3%
Free cash flow CAGR (3Y) 47.9% – –

Profitability

14 metrics
MetricADPTTEMGRAL
Gross margin 75.6% 64.0% 48.0%
EBITDA margin -7.0% – -257.6%
Operating margin -12.2% -19.8% -355.7%
Pretax margin -13.1% -17.6% -336.8%
Net margin -20.7% -17.8% -249.1%
FCF margin -7.8% -18.4% -188.4%
Operating cash flow margin -6.8% -16.6% -187.5%
Return on equity -34.1% -57.3% -15.5%
Return on assets -11.2% -11.0% -13.9%
Return on invested capital – -52.0% –
Return on capital employed -7.7% -15.2% -20.4%
Asset turnover 0.5x 0.6x 0.1x
Cash conversion (OCF / net income) 0.3x 0.9x 0.8x
Stock comp / revenue 15.9% 13.0% 40.9%

Financial Health

11 metrics
MetricADPTTEMGRAL
Debt / assets – – –
Debt / equity – – –
Net debt / EBITDA – – –
Debt / FCF – – –
Liabilities / assets 76.5% 81.2% 10.6%
Equity / assets 23.5% 18.8% 89.4%
Interest coverage -3.3x -5.1x –
Current ratio 4.8x 3.3x 10.9x
Quick ratio 4.5x 3.1x 10.6x
Cash ratio 3.9x 2.1x 10.3x
Altman Z-score 3.19 3.13 8.04

Shareholder Returns

7 metrics
MetricADPTTEMGRAL
Dividend yield – – –
Net buyback yield -0.5% – –
Shareholder yield -0.5% 0.0% –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusADPTTEMGRAL
EPS, next fiscal year $-0.57FY2026 $-0.21FY2026 $-9.05FY2026
Revenue, next fiscal year $284.03MFY2026 $1.64BFY2026 $169.78MFY2026
Revenue growth, next FY +2.5%FY2026 +29.0%FY2026 +15.4%FY2026
Revenue growth, the year after +33.8% +24.1% +38.2%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersADPTTEMGRAL
Held by institutions 97.2% 63.0% 85.4%
Institutions holding 299 483 372
Change in shares held, QoQ +2.5% +5.0% +8.4%
Institutions buying 160 284 182
Institutions selling 87 118 100
Buyers to sellers 1.84 2.41 1.82

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ADPTTEMGRAL
ADPT 1.00 0.57 0.47
TEM 0.57 1.00 0.41
GRAL 0.47 0.41 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ADPT, TEM and GRAL?

Tempus AI (TEM) is the largest by market capitalisation: Adaptive Biotechnologies (ADPT) $4.40B, Tempus AI (TEM) $12.64B, Grail (GRAL) $6.73B.

Which company is growing faster?

Tempus AI (TEM) grew revenue fastest over the trailing twelve months: Adaptive Biotechnologies (ADPT) +50.1%, Tempus AI (TEM) +50.4%, Grail (GRAL) +17.1%.

Which company is more profitable?

Tempus AI (TEM) has the highest net margin (Adaptive Biotechnologies (ADPT) -20.7%, Tempus AI (TEM) -17.8%, Grail (GRAL) -249.1%).

Which stock has performed better?

Over the past year Grail (GRAL) returned the most: Adaptive Biotechnologies (ADPT) +61.6%, Tempus AI (TEM) -21.2%, Grail (GRAL) +77.2%. Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Adaptive Biotechnologies (ADPT) has been the steadiest (Adaptive Biotechnologies (ADPT) 67.8%, Tempus AI (TEM) 76.8%, Grail (GRAL) 111.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ADPT, TEM and GRAL?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Tempus AI (TEM) leads on 3. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.