ADPT vs DGX vs NTRA Stock Comparison

Adaptive Biotechnologies, Quest Diagnostics and Natera Prices as of Oct 28, 2026 Peers: Industry group
DGX Quest Diagnostics Inc
$245.73 +3.4% 1M +37.8% 1Y
Market cap
$27.75B
P/E
24.6x
Revenue (TTM)
$11.84B
Div. yield
0.01%
Diagnostic Labs Healthcare
5 wins
NTRA Natera, Inc.
$424.42 +3.1% 1M +123.9% 1Y
Market cap
$62.03B
P/E
–
Revenue (TTM)
$2.71B
Div. yield
–
Diagnostic Labs Healthcare
3 wins

Head to Head

9 decided of 12

Quest Diagnostics leads on 5 of the 12 questions below (Quest Diagnostics 5, Natera 3, Adaptive Biotechnologies 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionADPTDGXNTRALeader
Larger companyMarket capitalisation $4.54B $27.75B $62.03B NTRA
Cheaper on earningsLower P/E, profitable companies only -71.0x 24.6x -322.4x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 22.4x — –
Faster revenue growthRevenue growth, trailing twelve months +50.1% +9.1% +37.8% ADPT
More profitableNet margin, trailing twelve months -20.7% 9.5% -7.1% DGX
Better return on capitalReturn on invested capital — 9.9% -11.7% DGX
Less leveragedLower net debt / EBITDA — 2.1x 4.5x DGX
Higher dividend yieldTrailing dividend yield 0.00% 0.01% 0.00% –
Better 1-year returnPrice return, last 12 months +67.9% +37.8% +123.9% NTRA
Better 5-year returnAnnualised price return, 5 years -3.2%/yr +10.9%/yr +30.0%/yr NTRA
Less volatileAnnualised volatility, 1 year 67.8% 23.7% 47.9% DGX
Higher overall scoreMean of the five percentile scores vs peers 43/100 64/100 51/100 DGX

Percentile Scorecard

ADPTDGXNTRA

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisADPTDGXNTRA
Valuation 14 #79 of 92 70 #28 of 92 17 #77 of 92
Growth 85 #14 of 87 38 #54 of 87 71 #26 of 87
Profitability 24 #66 of 86 79 #19 of 86 32 #59 of 86
Financial Health 66 #34 of 97 55 #44 of 97 85 #15 of 97
Shareholder Returns 26 #41 of 55 76 #14 of 55 48 #29 of 55
Overall 43 64 51
  • ADPT ranked among 102 companies in Healthcare Providers
  • DGX ranked among 102 companies in Healthcare Providers
  • NTRA ranked among 102 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodADPTDGXNTRASPY
1 month -0.5%+3.4%+3.1% +0.9%
3 months +25.8%+4.5%+67.2% +5.9%
6 months +109.7%+29.8%+117.9% +8.5%
Year to date +74.7%+41.6%+85.3% +13.3%
1 year +67.9%+37.8%+123.9% +12.4%
3 years +567.5%+92.5%+1,009.3% +88.1%
3 years, per year +88.4%+24.4%+123.1% +23.5%
5 years -15.1%+67.4%+270.4% +68.2%
5 years, per year -3.2%+10.9%+30.0% +11.0%
10 years —+205.5%+4,887.3% +263.4%
10 years, per year —+11.8%+47.8% +13.8%

Risk

MeasureADPTDGXNTRASPY
Volatility, 1Y 67.8%23.7%47.9% 12.7%
Downside volatility, 1Y 63.9%18.8%44.6% 12.7%
Beta vs S&P 500, 1Y 1.68-0.091.24 1.00
Return / volatility, 1Y 1.001.592.59 0.98
Max drawdown, 5Y -93.6%-30.3%-76.4% -25.4%
From 52-week high -4.9%-0.7%-0.3% -0.9%
52-week high $29.84$247.47$425.64 $779.14
52-week low $12.41$173.49$182.65 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleADPTDGXNTRA
P/E now vs peer median -71.0xmedian 25.6x 23.9xmedian 25.6x -316.1xmedian 25.6x
P/S now vs peer median 14.6xmedian 1.6x 2.3xmedian 1.6x 22.5xmedian 1.6x
EV/EBITDA now vs peer median -193.7xmedian 16.3x 13.8xmedian 16.3x -267.3xmedian 16.3x
P/FCF now vs peer median -187.8xmedian 21.3x 19.7xmedian 21.3x 723.9xmedian 21.3x
P/B now vs peer median 30.0xmedian 3.3x 3.4xmedian 3.3x 33.5xmedian 3.3x
PEG now vs peer median -2.16median 0.68 1.64median 0.68 -9.52median 0.68

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsADPTDGXNTRA
Revenue $308.08M $11.84B $2.71B
Gross profit $232.83M $3.92B $1.71B
Operating income -$37.46M $1.72B -$289.67M
Net income -$63.99M $1.18B -$192.36M
Free cash flow -$24.03M $1.38B $84.20M
R&D $88.21M – $787.38M
EPS (diluted) $-0.40 $10.08 $-1.34
Cash & equivalents $169.87M $797.00M $1.10B
Total debt – $5.55B $80.29M
Shares (diluted) 159.86M 112.00M 143.28M
Enterprise value $3.53B $25.51B $57.71B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricADPTDGXNTRA
P/E -71.0x 23.9x -316.1x
P/FCF -187.8x 19.7x 723.9x
P/Operating cash flow -214.8x 13.9x 267.1x
P/S 14.6x 2.3x 22.5x
P/B 30.0x 3.4x 33.5x
P/Tangible book 30.1x 4.3x 41.7x
EV/EBITDA -193.7x 13.8x -267.3x
EV/EBIT -111.3x 18.4x -206.9x
EV/Revenue 13.5x 2.7x 22.1x
EV/FCF -173.4x 23.1x 711.8x
EV/Operating cash flow -198.4x 16.3x 262.6x
PEG (3Y EPS CAGR) -2.16 1.64 -9.52

Growth

14 metrics
MetricADPTDGXNTRA
Revenue growth (1Y) 50.1% 9.1% 37.8%
Revenue CAGR (3Y) 17.6% 8.4% 42.7%
Gross profit growth (1Y) 71.8% 8.5% 43.6%
Gross profit CAGR (3Y) 24.2% 8.4% 68.1%
Operating income growth (1Y) 69.1% 12.5% 1.3%
Operating income CAGR (3Y) 41.8% 15.1% 17.3%
Net income growth (1Y) 47.2% 15.0% 24.0%
Net income CAGR (3Y) 30.5% 12.9% 27.8%
EPS growth (1Y) 49.9% 17.6% 27.7%
EPS CAGR (3Y) 32.9% 14.6% 33.2%
Operating cash flow growth (1Y) 73.9% 3.5% 22.2%
Operating cash flow CAGR (3Y) 48.6% 21.8% 38.6%
Free cash flow growth (1Y) 71.0% -1.3% -26.8%
Free cash flow CAGR (3Y) 47.9% 32.1% 30.4%

Profitability

14 metrics
MetricADPTDGXNTRA
Gross margin 75.6% 33.1% 63.2%
EBITDA margin -7.0% 19.5% -8.3%
Operating margin -12.2% 14.6% -10.7%
Pretax margin -13.1% 12.6% -9.3%
Net margin -20.7% 9.5% -7.1%
FCF margin -7.8% 11.6% 3.1%
Operating cash flow margin -6.8% 16.5% 8.4%
Return on equity -34.1% 15.0% -10.7%
Return on assets -11.2% 6.9% -7.3%
Return on invested capital – 9.9% -11.7%
Return on capital employed -7.7% 11.3% -13.9%
Asset turnover 0.5x 0.7x 1.0x
Cash conversion (OCF / net income) 0.3x 1.7x -1.2x
Stock comp / revenue 15.9% 0.7% 14.1%

Financial Health

11 metrics
MetricADPTDGXNTRA
Debt / assets – 32.2% 3.0%
Debt / equity – 0.7x 0.0x
Net debt / EBITDA – 2.1x 4.5x
Debt / FCF – 4.0x 1.0x
Liabilities / assets 76.5% 53.8% 31.5%
Equity / assets 23.5% 46.2% 68.5%
Interest coverage -3.3x 6.5x -75.9x
Current ratio 4.8x 1.7x 3.0x
Quick ratio 4.5x 1.4x 2.8x
Cash ratio 3.9x 0.4x 2.0x
Altman Z-score 3.33 3.72 43.36

Shareholder Returns

7 metrics
MetricADPTDGXNTRA
Dividend yield – 1.4% –
Net buyback yield -0.5% 1.2% -0.1%
Shareholder yield -0.5% 2.6% -0.1%
Payout ratio (earnings) – 31.3% –
Payout ratio (FCF) – 26.8% –
Dividend growth (1Y) – 6.3% –
Dividend CAGR (3Y) – 6.1% –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusADPTDGXNTRA
Forward P/E – 22.4xFY2026 –
EPS, next fiscal year $-0.57FY2026 $10.96FY2026 $-1.48FY2026
EPS growth, next FY – +11.3%FY2026 –
EPS growth, the year after – +6.8% –
Revenue, next fiscal year $284.03MFY2026 $11.25BFY2026 $3.07BFY2026
Revenue growth, next FY +2.5%FY2026 +1.9%FY2026 +32.8%FY2026
Revenue growth, the year after +33.8% +7.7% +7.2%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersADPTDGXNTRA
Held by institutions 97.2% 94.4% 95.5%
Institutions holding 299 1,096 847
Change in shares held, QoQ +2.5% +2.7% +2.7%
Institutions buying 160 549 513
Institutions selling 87 341 240
Buyers to sellers 1.84 1.61 2.14

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ADPTDGXNTRA
ADPT 1.00 0.23 0.56
DGX 0.23 1.00 0.20
NTRA 0.56 0.20 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ADPT, DGX and NTRA?

Natera (NTRA) is the largest by market capitalisation: Adaptive Biotechnologies (ADPT) $4.54B, Quest Diagnostics (DGX) $27.75B, Natera (NTRA) $62.03B.

Which company is growing faster?

Adaptive Biotechnologies (ADPT) grew revenue fastest over the trailing twelve months: Adaptive Biotechnologies (ADPT) +50.1%, Quest Diagnostics (DGX) +9.1%, Natera (NTRA) +37.8%.

Which company is more profitable?

Quest Diagnostics (DGX) has the highest net margin (Adaptive Biotechnologies (ADPT) -20.7%, Quest Diagnostics (DGX) 9.5%, Natera (NTRA) -7.1%). On return on invested capital, Quest Diagnostics (DGX) leads (Quest Diagnostics (DGX) 9.9%, Natera (NTRA) -11.7%).

Which stock has performed better?

Over the past year Natera (NTRA) returned the most: Adaptive Biotechnologies (ADPT) +67.9%, Quest Diagnostics (DGX) +37.8%, Natera (NTRA) +123.9%. Over five years, Natera (NTRA) compounded fastest (Adaptive Biotechnologies (ADPT) -3.2%/yr, Quest Diagnostics (DGX) +10.9%/yr, Natera (NTRA) +30.0%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Adaptive Biotechnologies (ADPT) 0.00%, Quest Diagnostics (DGX) 0.01%, Natera (NTRA) 0.00%. Adaptive Biotechnologies (ADPT) and Natera (NTRA) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Quest Diagnostics (DGX) has been the steadiest (Adaptive Biotechnologies (ADPT) 67.8%, Quest Diagnostics (DGX) 23.7%, Natera (NTRA) 47.9%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ADPT, DGX and NTRA?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Quest Diagnostics (DGX) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.