ABVX vs REGN vs INSM Stock Comparison

Abivax, Regeneron Pharmaceuticals and Insmed Prices as of Oct 28, 2026 Peers: Industry group
ABVX Abivax S.A.
$89.84 -7.2% 1M -4.7% 1Y
Market cap
$6.17B
P/E
–
Revenue (TTM)
-$76.25M
Div. yield
–
Biotechnology Healthcare
INSM INSMED Inc
$96.98 -17.6% 1M -41.3% 1Y
Market cap
$24.23B
P/E
–
Revenue (TTM)
$1.14B
Div. yield
–
Biotechnology Healthcare
2 wins

Head to Head

9 decided of 12

Regeneron Pharmaceuticals leads on 7 of the 12 questions below (Regeneron Pharmaceuticals 7, Insmed 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionABVXREGNINSMLeader
Larger companyMarket capitalisation $6.17B $83.83B $24.23B REGN
Cheaper on earningsLower P/E, profitable companies only -13.2x 19.4x -27.7x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 14.2x — –
Faster revenue growthRevenue growth, trailing twelve months -463.2% +9.3% +185.8% INSM
More profitableNet margin, trailing twelve months — 27.9% -76.9% REGN
Better return on capitalReturn on invested capital -74.9% 9.6% -66.0% REGN
Less leveragedLower net debt / EBITDA 1.4x -1.4x 0.8x REGN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -4.7% +24.3% -41.3% REGN
Better 5-year returnAnnualised price return, 5 years — +4.9%/yr +26.3%/yr INSM
Less volatileAnnualised volatility, 1 year 91.1% 30.9% 61.8% REGN
Higher overall scoreMean of the five percentile scores vs peers 55/100 72/100 60/100 REGN

Percentile Scorecard

ABVXREGNINSM

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisABVXREGNINSM
Valuation 73 #169 of 625 89 #70 of 625 66 #214 of 625
Growth 8 #554 of 602 42 #352 of 602 68 #192 of 602
Profitability 26 #408 of 549 90 #54 of 549 61 #213 of 549
Financial Health 82 #121 of 654 74 #173 of 654 40 #392 of 654
Shareholder Returns 89 #43 of 367 65 #129 of 367 66 #127 of 367
Overall 55 72 60
  • ABVX ranked among 672 companies in Pharmaceuticals and Biotechnology
  • REGN ranked among 672 companies in Pharmaceuticals and Biotechnology
  • INSM ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodABVXREGNINSMSPY
1 month -7.2%+8.1%-17.6% +0.9%
3 months -24.4%+16.9%-6.0% +5.9%
6 months -15.4%+18.5%-28.2% +8.5%
Year to date -33.4%+5.4%-44.3% +13.3%
1 year -4.7%+24.3%-41.3% +12.4%
3 years +868.1%+4.9%+306.1% +88.1%
3 years, per year +113.2%+1.6%+59.6% +23.5%
5 years —+27.1%+221.7% +68.2%
5 years, per year —+4.9%+26.3% +11.0%
10 years —+128.6%+616.2% +263.4%
10 years, per year —+8.6%+21.8% +13.8%

Risk

MeasureABVXREGNINSMSPY
Volatility, 1Y 91.1%30.9%61.8% 12.7%
Downside volatility, 1Y 94.5%29.9%60.5% 12.7%
Beta vs S&P 500, 1Y 0.960.450.51 1.00
Return / volatility, 1Y -0.050.79-0.67 0.98
Max drawdown, 5Y -67.5%-59.8%-56.5% -25.4%
From 52-week high -38.2%-4.5%-54.1% -0.9%
52-week high $145.31$852.03$211.41 $779.14
52-week low $72.50$600.66$91.88 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleABVXREGNINSM
P/E now vs peer median -13.3xmedian 17.4x 19.3xmedian 17.4x -24.1xmedian 17.4x
P/S now vs peer median -92.5xmedian 9.1x 5.4xmedian 9.1x 18.6xmedian 9.1x
EV/EBITDA now vs peer median -19.4xmedian 17.1x 17.7xmedian 17.1x -25.2xmedian 17.1x
P/FCF now vs peer median -30.6xmedian 19.0x 22.2xmedian 19.0x -26.2xmedian 19.0x
P/B now vs peer median 16.9xmedian 2.2x 2.6xmedian 2.2x 27.9xmedian 2.2x
PEG now vs peer median —median 0.34 7.26median 0.34 -3.29median 0.34

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsABVXREGNINSM
Revenue -$76.25M $15.53B $1.14B
Gross profit – $13.18B $949.42M
Operating income -$341.36M $3.84B -$840.62M
Net income -$467.93M $4.33B -$875.36M
Free cash flow -$230.23M $3.76B -$807.67M
R&D $242.27M $6.28B $860.85M
EPS (diluted) $-6.73 $40.84 $-4.03
Cash & equivalents $443.17M $2.46B $544.80M
Total debt $156.48K $1.99B $543.51M
Shares (diluted) 69.53M 106.00M 217.35M
Enterprise value $3.81B $50.03B $18.73B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricABVXREGNINSM
P/E -13.3x 19.3x -24.1x
P/FCF -30.6x 22.2x -26.2x
P/Operating cash flow -30.7x 17.9x -27.2x
P/S -92.5x 5.4x 18.6x
P/B 16.9x 2.6x 27.9x
P/Tangible book 17.2x 2.7x 31.9x
EV/EBITDA -19.4x 17.7x -25.2x
EV/EBIT -19.3x 20.2x -24.4x
EV/Revenue -86.4x 5.0x 18.1x
EV/FCF -28.6x 20.6x -25.4x
EV/Operating cash flow -28.6x 16.6x -26.4x
PEG (3Y EPS CAGR) – 7.26 -3.29

Growth

14 metrics
MetricABVXREGNINSM
Revenue growth (1Y) -463.2% 9.3% 185.8%
Revenue CAGR (3Y) – 7.0% 61.6%
Gross profit growth (1Y) – 8.4% 215.0%
Gross profit CAGR (3Y) – 6.4% 64.7%
Operating income growth (1Y) 0.2% 0.1% 16.3%
Operating income CAGR (3Y) – -3.9% -8.2%
Net income growth (1Y) -120.1% -2.9% 15.4%
Net income CAGR (3Y) – 0.2% -8.0%
EPS growth (1Y) -99.6% -0.5% 26.3%
EPS CAGR (3Y) – 2.7% 7.3%
Operating cash flow growth (1Y) -56.0% -1.3% 7.8%
Operating cash flow CAGR (3Y) – -0.4% -19.0%
Free cash flow growth (1Y) -55.6% -2.4% 7.0%
Free cash flow CAGR (3Y) – -3.3% -19.3%

Profitability

14 metrics
MetricABVXREGNINSM
Gross margin – 84.9% 83.5%
EBITDA margin – 28.1% -71.7%
Operating margin – 24.7% -73.9%
Pretax margin – 33.3% -76.4%
Net margin – 27.9% -76.9%
FCF margin – 24.2% -71.0%
Operating cash flow margin 301.6% 30.1% -68.5%
Return on equity -102.8% 13.7% -119.7%
Return on assets -81.0% 10.5% -41.9%
Return on invested capital -74.9% 9.6% -66.0%
Return on capital employed -68.9% 10.7% -50.9%
Asset turnover -0.1x 0.4x 0.5x
Cash conversion (OCF / net income) 0.5x 1.1x 0.9x
Stock comp / revenue -97.6% 6.4% 13.8%

Financial Health

11 metrics
MetricABVXREGNINSM
Debt / assets 0.0% 4.8% 25.8%
Debt / equity 0.0x 0.1x 0.7x
Net debt / EBITDA 1.4x -1.4x 0.8x
Debt / FCF 0.0x 0.5x -0.7x
Liabilities / assets 20.8% 24.0% 64.0%
Equity / assets 79.2% 76.0% 36.0%
Interest coverage -4.1x 69.4x -10.3x
Current ratio 6.0x 3.3x 3.7x
Quick ratio 5.7x 2.6x 3.1x
Cash ratio 5.7x 1.4x 2.6x
Altman Z-score 35.16 7.32 5.48

Shareholder Returns

7 metrics
MetricABVXREGNINSM
Dividend yield – 0.5% –
Net buyback yield 0.0% 3.0% -0.6%
Shareholder yield 0.0% 3.5% -0.6%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusABVXREGNINSM
Forward P/E – 14.2xFY2026 –
EPS, next fiscal year $-4.42FY2026 $57.08FY2026 $-1.61FY2026
EPS growth, next FY – +28.8%FY2026 –
EPS growth, the year after – +15.5% –
Revenue, next fiscal year $5.07MFY2026 $17.05BFY2026 $1.92BFY2026
Revenue growth, next FY -5.0%FY2026 +18.9%FY2026 +217.1%FY2026
Revenue growth, the year after +1,467.2% +13.0% +60.4%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersABVXREGNINSM
Held by institutions 79.0% 66.2% 100.0%
Institutions holding 301 1,325 669
Change in shares held, QoQ +10.1% +3.8% +3.4%
Institutions buying 189 604 368
Institutions selling 99 534 229
Buyers to sellers 1.91 1.13 1.61

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ABVXREGNINSM
ABVX 1.00 0.17 0.17
REGN 0.17 1.00 0.20
INSM 0.17 0.20 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, ABVX, REGN and INSM?

Regeneron Pharmaceuticals (REGN) is the largest by market capitalisation: Abivax (ABVX) $6.17B, Regeneron Pharmaceuticals (REGN) $83.83B, Insmed (INSM) $24.23B.

Which company is growing faster?

Insmed (INSM) grew revenue fastest over the trailing twelve months: Abivax (ABVX) -463.2%, Regeneron Pharmaceuticals (REGN) +9.3%, Insmed (INSM) +185.8%.

Which company is more profitable?

Regeneron Pharmaceuticals (REGN) has the highest net margin (Regeneron Pharmaceuticals (REGN) 27.9%, Insmed (INSM) -76.9%). On return on invested capital, Regeneron Pharmaceuticals (REGN) leads (Abivax (ABVX) -74.9%, Regeneron Pharmaceuticals (REGN) 9.6%, Insmed (INSM) -66.0%).

Which stock has performed better?

Over the past year Regeneron Pharmaceuticals (REGN) returned the most: Abivax (ABVX) -4.7%, Regeneron Pharmaceuticals (REGN) +24.3%, Insmed (INSM) -41.3%. Over five years, Insmed (INSM) compounded fastest (Regeneron Pharmaceuticals (REGN) +4.9%/yr, Insmed (INSM) +26.3%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Regeneron Pharmaceuticals (REGN) has been the steadiest (Abivax (ABVX) 91.1%, Regeneron Pharmaceuticals (REGN) 30.9%, Insmed (INSM) 61.8%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ABVX, REGN and INSM?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Regeneron Pharmaceuticals (REGN) leads on 7. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.