A vs TXG vs TWST Stock Comparison

Agilent Technologies, 10x Genomics and Twist Bioscience Prices as of Oct 26, 2026 Peers: Industry group
A Agilent Technologies, Inc.
$175.96 +1.8% 1M +18.9% 1Y
Market cap
$50.15B
P/E
34.8x
Revenue (TTM)
$7.37B
Div. yield
0.01%
Life Sciences Tools Healthcare
6 wins
TXG 10x Genomics, Inc.
$72.96 -14.9% 1M +429.8% 1Y
Market cap
$10.15B
P/E
–
Revenue (TTM)
$616.91M
Div. yield
–
Life Sciences Tools Healthcare
1 win
TWST Twist Bioscience Corp
$145.25 -20.6% 1M +325.8% 1Y
Market cap
$9.99B
P/E
–
Revenue (TTM)
$431.80M
Div. yield
–
Life Sciences Tools Healthcare
2 wins

Head to Head

9 decided of 12

Agilent Technologies leads on 6 of the 12 questions below (Agilent Technologies 6, Twist Bioscience 2, 10x Genomics 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionATXGTWSTLeader
Larger companyMarket capitalisation $50.15B $10.15B $9.99B A
Cheaper on earningsLower P/E, profitable companies only 34.8x -135.1x -73.1x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 26.9x — — –
Faster revenue growthRevenue growth, trailing twelve months +8.6% -4.3% +19.2% TWST
More profitableNet margin, trailing twelve months 19.5% -12.2% -31.7% A
Better return on capitalReturn on invested capital 13.1% — -31.1% A
Less leveragedLower net debt / EBITDA 1.1x — 1.3x A
Higher dividend yieldTrailing dividend yield 0.01% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +18.9% +429.8% +325.8% TXG
Better 5-year returnAnnualised price return, 5 years +2.5%/yr -14.4%/yr +4.9%/yr TWST
Less volatileAnnualised volatility, 1 year 32.4% 73.8% 78.4% A
Higher overall scoreMean of the five percentile scores vs peers 62/100 61/100 49/100 A

Percentile Scorecard

ATXGTWST

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisATXGTWST
Valuation 58 #97 of 228 43 #130 of 228 30 #160 of 228
Growth 36 #141 of 221 66 #76 of 221 53 #105 of 221
Profitability 91 #20 of 208 63 #77 of 208 40 #126 of 208
Financial Health 55 #108 of 239 68 #78 of 239 74 #64 of 239
Shareholder Returns 71 #40 of 137 67 #46 of 137 50 #69 of 137
Overall 62 61 49
  • A ranked among 248 companies in Medical Devices and Diagnostics
  • TXG ranked among 248 companies in Medical Devices and Diagnostics
  • TWST ranked among 248 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodATXGTWSTSPY
1 month +1.8%-14.9%-20.6% -0.8%
3 months +27.6%+58.9%+67.8% +3.5%
6 months +52.2%+227.5%+138.1% +7.0%
Year to date +29.3%+347.3%+357.9% +12.2%
1 year +18.9%+429.8%+325.8% +13.0%
3 years +71.2%+100.4%+861.3% +86.3%
3 years, per year +19.6%+26.1%+112.7% +23.1%
5 years +13.3%-54.1%+27.1% +68.6%
5 years, per year +2.5%-14.4%+4.9% +11.0%
10 years +305.7%—— +258.0%
10 years, per year +15.0%—— +13.6%

Risk

MeasureATXGTWSTSPY
Volatility, 1Y 32.4%73.8%78.4% 12.7%
Downside volatility, 1Y 27.5%66.1%69.5% 12.7%
Beta vs S&P 500, 1Y 0.882.212.67 1.00
Return / volatility, 1Y 0.585.824.15 1.02
Max drawdown, 5Y -39.6%-96.1%-91.5% -25.4%
From 52-week high -1.0%-25.4%-29.1% -1.8%
52-week high $177.72$97.74$205.00 $779.14
52-week low $110.24$12.44$25.45 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleATXGTWST
P/E now vs peer median 34.5xmedian 30.6x -126.2xmedian 30.6x -66.3xmedian 30.6x
P/S now vs peer median 6.7xmedian 3.0x 15.4xmedian 3.0x 21.1xmedian 3.0x
EV/EBITDA now vs peer median 27.1xmedian 17.5x -212.9xmedian 17.5x -74.9xmedian 17.5x
P/FCF now vs peer median 39.2xmedian 23.3x 78.3xmedian 23.3x -92.8xmedian 23.3x
P/B now vs peer median 6.7xmedian 2.4x 11.5xmedian 2.4x 20.4xmedian 2.4x
PEG now vs peer median 3.51median 0.87 -4.70median 0.87 -4.19median 0.87

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsATXGTWST
Revenue $7.37B $616.91M $431.80M
Gross profit $3.97B $432.03M $224.39M
Operating income $1.64B -$88.38M -$144.98M
Net income $1.44B -$75.13M -$136.80M
Free cash flow $1.27B $121.44M -$98.12M
R&D $485.00M $226.80M $71.86M
EPS (diluted) $5.09 $-0.58 $-2.19
Cash & equivalents $1.76B – $117.44M
Total debt $3.95B – $15.00M
Shares (diluted) 283.00M 129.98M 62.40M
Enterprise value $43.03B $9.95B $9.22B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricATXGTWST
P/E 34.5x -126.2x -66.3x
P/FCF 39.2x 78.3x -92.8x
P/Operating cash flow 30.8x 74.8x -171.5x
P/S 6.7x 15.4x 21.1x
P/B 6.7x 11.5x 20.4x
P/Tangible book 7.7x 12.4x 21.0x
EV/EBITDA 27.1x -212.9x -74.9x
EV/EBIT 31.6x -107.0x -61.7x
EV/Revenue 7.0x 15.3x 20.7x
EV/FCF 40.9x 77.9x -91.2x
EV/Operating cash flow 32.2x 74.4x -168.7x
PEG (3Y EPS CAGR) 3.51 -4.70 -4.19

Growth

14 metrics
MetricATXGTWST
Revenue growth (1Y) 8.6% -4.3% 19.2%
Revenue CAGR (3Y) 1.8% 2.8% 22.4%
Gross profit growth (1Y) 11.2% -3.5% 25.8%
Gross profit CAGR (3Y) 3.7% 1.1% 35.1%
Operating income growth (1Y) 13.5% 12.1% -1.8%
Operating income CAGR (3Y) 5.1% 20.9% 13.5%
Net income growth (1Y) 18.0% 11.2% -60.6%
Net income CAGR (3Y) 8.3% 24.2% 13.2%
EPS growth (1Y) 18.9% 14.9% -57.5%
EPS CAGR (3Y) 9.8% 26.8% 15.8%
Operating cash flow growth (1Y) 7.6% 89.8% -3.8%
Operating cash flow CAGR (3Y) -1.9% 135.5% 24.4%
Free cash flow growth (1Y) 16.5% 113.5% -42.8%
Free cash flow CAGR (3Y) -3.7% 44.7% 15.9%

Profitability

14 metrics
MetricATXGTWST
Gross margin 53.8% 70.0% 52.0%
EBITDA margin 25.9% -7.2% -27.7%
Operating margin 22.2% -14.3% -33.6%
Pretax margin 22.5% -12.1% -31.5%
Net margin 19.5% -12.2% -31.7%
FCF margin 17.2% 19.7% -22.7%
Operating cash flow margin 21.8% 20.6% -12.3%
Return on equity 19.9% -9.2% -30.4%
Return on assets 10.7% -7.3% -20.3%
Return on invested capital 13.1% – -31.1%
Return on capital employed 14.6% -9.8% -26.2%
Asset turnover 0.5x 0.6x 0.6x
Cash conversion (OCF / net income) 1.1x -1.7x 0.4x
Stock comp / revenue 1.8% 16.0% 15.4%

Financial Health

11 metrics
MetricATXGTWST
Debt / assets 28.3% – 2.2%
Debt / equity 0.5x – 0.0x
Net debt / EBITDA 1.1x – 1.3x
Debt / FCF 3.1x – -0.2x
Liabilities / assets 47.3% 19.9% 33.7%
Equity / assets 52.7% 80.1% 66.3%
Interest coverage 15.5x – –
Current ratio 2.1x 5.7x 2.7x
Quick ratio 1.4x 0.8x 1.9x
Cash ratio 0.8x 0.4x 1.4x
Altman Z-score 5.82 26.75 21.41

Shareholder Returns

7 metrics
MetricATXGTWST
Dividend yield 0.6% – –
Net buyback yield 0.6% -0.1% -0.2%
Shareholder yield 1.2% -0.1% -0.2%
Payout ratio (earnings) 19.9% – –
Payout ratio (FCF) 22.6% – –
Dividend growth (1Y) 2.1% – –
Dividend CAGR (3Y) 3.1% – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusATXGTWST
Forward P/E 26.9xFY2026 – –
EPS, next fiscal year $6.54FY2026 $-0.79FY2026 $-2.02FY2026
EPS growth, next FY +17.0%FY2026 – –
EPS growth, the year after +0.3% – –
Revenue, next fiscal year $7.87BFY2026 $580.42MFY2026 $469.33MFY2026
Revenue growth, next FY +15.3%FY2026 -9.7%FY2026 +24.6%FY2026
Revenue growth, the year after -5.6% +24.6% +21.5%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersATXGTWST
Held by institutions 92.6% 100.0% 100.0%
Institutions holding 1,122 389 335
Change in shares held, QoQ +3.2% +2.4% -0.8%
Institutions buying 599 197 188
Institutions selling 350 137 102
Buyers to sellers 1.71 1.44 1.84

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ATXGTWST
A 1.00 0.52 0.51
TXG 0.52 1.00 0.60
TWST 0.51 0.60 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, A, TXG and TWST?

Agilent Technologies (A) is the largest by market capitalisation: Agilent Technologies (A) $50.15B, 10x Genomics (TXG) $10.15B, Twist Bioscience (TWST) $9.99B.

Which company is growing faster?

Twist Bioscience (TWST) grew revenue fastest over the trailing twelve months: Agilent Technologies (A) +8.6%, 10x Genomics (TXG) -4.3%, Twist Bioscience (TWST) +19.2%.

Which company is more profitable?

Agilent Technologies (A) has the highest net margin (Agilent Technologies (A) 19.5%, 10x Genomics (TXG) -12.2%, Twist Bioscience (TWST) -31.7%). On return on invested capital, Agilent Technologies (A) leads (Agilent Technologies (A) 13.1%, Twist Bioscience (TWST) -31.1%).

Which stock has performed better?

Over the past year 10x Genomics (TXG) returned the most: Agilent Technologies (A) +18.9%, 10x Genomics (TXG) +429.8%, Twist Bioscience (TWST) +325.8%. Over five years, Twist Bioscience (TWST) compounded fastest (Agilent Technologies (A) +2.5%/yr, 10x Genomics (TXG) -14.4%/yr, Twist Bioscience (TWST) +4.9%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Agilent Technologies (A) 0.01%, 10x Genomics (TXG) 0.00%, Twist Bioscience (TWST) 0.00%. 10x Genomics (TXG) and Twist Bioscience (TWST) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Agilent Technologies (A) has been the steadiest (Agilent Technologies (A) 32.4%, 10x Genomics (TXG) 73.8%, Twist Bioscience (TWST) 78.4%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, A, TXG and TWST?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Agilent Technologies (A) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.