As of April 22, 2026, GeneDx Holdings's top three insider holders are Eli Casdin (Director, 102.15Mn shares), School Of Medicine At Mount Sinai Icahn (TenPercentOwner, 94.61Mn shares), Eli Casdin (Director, 15.99Mn shares).
| Holder | Position | Shares (Direct) | Shares (Indirect) | Report Date |
|---|---|---|---|---|
| Eli Casdin | - | 0 | 102,151,785 | 02 Feb, 2023 |
| School Of Medicine At Mount Sinai Icahn | - | 94,605,473 | 0 | 05 May, 2022 |
| Eli Casdin | - | 0 | 15,993,750 | 26 Jul, 2021 |
| Joshua Ruch | - | 0 | 6,410,714 | 03 Feb, 2023 |
| Capital, Llc Casdin | - | 3,507,164 | 0 | 05 Aug, 2024 |
| Keith A. Meister | - | 0 | 3,228,150 | 05 Mar, 2026 |
| Capital, Llc Casdin | - | 0 | 3,007,164 | 22 Aug, 2025 |
| School Of Medicine At Mount Sinai Icahn | - | 2,719,692 | 0 | 19 Nov, 2024 |
| Health, Inc. Opko | - | 2,646,972 | 0 | 19 Aug, 2024 |
| Joshua Ruch | - | 0 | 2,125,000 | 12 Jul, 2022 |
| Daniel Emmett Clark | Secretary And General Counsel | 312,207 | 0 | 27 Jul, 2022 |
| Isaac Ro | Chief Financial Officer | 244,041 | 0 | 10 Aug, 2022 |
| Eric Schadt | President Chief Rd Officer | 243,380 | 0 | 24 May, 2022 |
| Jason Ryan | Executive Chairman | 189,626 | 0 | 04 Jan, 2023 |
| Tactical Opportunities Associates Iii - Nq L.P. Blackstone | - | 0 | 162,309 | 03 May, 2022 |
| Tactical Opportunities Associates Iii - Nq L.P. Blackstone | - | 0 | 162,309 | 03 May, 2022 |
| Sema4 Holdings L.P. Bto | - | 0 | 162,309 | 03 May, 2022 |
| Joshua Ruch | - | 0 | 156,267 | 26 Nov, 2025 |
| Jason Ryan | - | 0 | 103,284 | 27 Aug, 2025 |
| Kareem Saad | Chief Transformation Officer | 101,765 | 0 | 05 Jan, 2023 |
| Katherine Stueland | Chief Executive Officer | 91,514 | 0 | 30 Mar, 2026 |
| Rachel E. Sherman | - | 58,290 | 0 | 04 May, 2023 |
| Richard C Jr Pfenniger | - | 41,506 | 0 | 23 Jun, 2025 |
| Emily M. Leproust | - | 37,836 | 0 | 12 May, 2022 |
| Nat Turner | - | 37,836 | 0 | 12 May, 2022 |
| Kevin Feeley | Chief Financial Officer | 34,580 | 0 | 30 Mar, 2026 |
| Shawn Assad | Chief Accounting Officer | 32,107 | 0 | 12 May, 2022 |
| Joshua Ruch | - | 29,723 | 0 | 23 Jun, 2025 |
| Kareem Saad | Chief Transformation Officer | 29,517 | 0 | 19 Mar, 2024 |
| Richard Miao | - | 24,867 | 0 | 26 Aug, 2022 |
| James Coffin | President And Coo | 22,903 | 0 | 03 Dec, 2021 |
| Eli Casdin | - | 20,518 | 0 | 07 Aug, 2025 |
| Keith A. Meister | - | 20,129 | 0 | 23 Jun, 2025 |
| Joshua Ruch | - | 17,114 | 0 | 18 Oct, 2022 |
| Michael J Pellini | - | 17,114 | 0 | 18 Oct, 2022 |
| Anthony Prentice | Chief Product Officer | 12,102 | 0 | 27 Jul, 2022 |
| Jason Ryan | Executive Chairman | 11,904 | 0 | 27 Aug, 2025 |
| Karen Ann White | Chief People Officer | 4,761 | 0 | 27 Jul, 2023 |
| Jason Ryan | Executive Chairman | 0 | 4,272 | 21 Nov, 2024 |
* Please note that the shares above only reflect shares from the fund portfolio and the institutional portfolio. Shares from the personal portfolio are excluded from this Institutional Ownership Page. See these insiders' latest transactions here on Insider Page.
| Transaction Date | Insider Name | Security Class | Transaction Type | Shares Traded | Price | Shares Remaining | Ownership | Code |
|---|---|---|---|---|---|---|---|---|
| 26 Mar, 2026 | Kevin Feeley | Class A Common Stock | A | 16,250 | $0.00 | 43,398 | D | M |
| 26 Mar, 2026 | Katherine Stueland | Class A Common Stock | A | 80,000 | $0.00 | 138,447 | D | M |
| 26 Mar, 2026 | Kevin Feeley | Class A Common Stock | D | 2,485 | $61.29 | 40,913 | D | S |
| 26 Mar, 2026 | Katherine Stueland | Class A Common Stock | D | 13,229 | $61.29 | 125,218 | D | S |
| 26 Mar, 2026 | Kevin Feeley | Class A Common Stock | D | 961 | $62.33 | 39,952 | D | S |
| 26 Mar, 2026 | Katherine Stueland | Class A Common Stock | D | 5,117 | $62.33 | 120,101 | D | S |
| 26 Mar, 2026 | Kevin Feeley | Class A Common Stock | D | 2,520 | $63.28 | 37,432 | D | S |
| 26 Mar, 2026 | Katherine Stueland | Class A Common Stock | D | 13,412 | $63.28 | 106,689 | D | S |
| 26 Mar, 2026 | Katherine Stueland | Class A Common Stock | D | 5,292 | $64.60 | 101,397 | D | S |
| 26 Mar, 2026 | Kevin Feeley | Class A Common Stock | D | 995 | $64.60 | 36,437 | D | S |
| 26 Mar, 2026 | Katherine Stueland | Class A Common Stock | D | 9,883 | $65.21 | 91,514 | D | S |
| 26 Mar, 2026 | Kevin Feeley | Class A Common Stock | D | 1,857 | $65.21 | 34,580 | D | S |
| 26 Mar, 2026 | Kevin Feeley | Restricted Stock Unit | D | 16,250 | $0.00 | 32,500 | D | M |
| 26 Mar, 2026 | Katherine Stueland | Restricted Stock Unit | D | 80,000 | $0.00 | 160,000 | D | M |
| 15 Mar, 2026 | Kevin Feeley | Class A Common Stock | A | 3,815 | $0.00 | 25,657 | D | M |
| 15 Mar, 2026 | Katherine Stueland | Class A Common Stock | A | 11,921 | $0.00 | 56,876 | D | M |
| 16 Mar, 2026 | Kevin Feeley | Class A Common Stock | A | 7,197 | $0.00 | 32,854 | D | M |
| 16 Mar, 2026 | Katherine Stueland | Class A Common Stock | A | 18,750 | $0.00 | 75,626 | D | M |
| 16 Mar, 2026 | Kevin Feeley | Class A Common Stock | D | 2,384 | $76.35 | 30,470 | D | S |
| 16 Mar, 2026 | Katherine Stueland | Class A Common Stock | D | 7,178 | $76.35 | 68,448 | D | S |