Data spanning the past 90 days through December 12, 2025 reveals that GeneDx Holdings's three principal insider shareholders consist of Director Capital, Llc Casdin (6.51Mn shares), Director Joshua Ruch (149.81K shares), Director Jason Ryan (115.19K shares).
| Holder | Position | Shares | Report Date |
|---|---|---|---|
| Eli Casdin | 453,376 | 07 Aug, 2025 | |
| Capital, Llc Casdin | 6,514,328 | 05 Aug, 2024 | |
| Keith A. Meister | 3,078,758 | 23 Jun, 2025 | |
| School Of Medicine At Mount Sinai Icahn | 2,719,692 | 19 Nov, 2024 | |
| Health, Inc. Opko | 2,646,972 | 19 Aug, 2024 | |
| Daniel Emmett Clark | Secretary And General Counsel | 9,460 | 27 Jul, 2022 |
| Isaac Ro | 7,394 | 10 Aug, 2022 | |
| Eric Schadt | President & Chief R&D Officer | 7,374 | 24 May, 2022 |
| Tactical Opportunities Associates Iii - Nq L.P. Blackstone | 4,918 | 03 May, 2022 | |
| Sema4 Holdings L.P. Bto | 4,918 | 03 May, 2022 | |
| Joshua Ruch | 149,806 | 23 Jun, 2025 | |
| Jason Ryan | 115,188 | 27 Aug, 2025 | |
| Rachel E. Sherman | 1,766 | 04 May, 2023 | |
| Richard C Jr Pfenniger | 41,506 | 23 Jun, 2025 | |
| Nat Turner | 1,146 | 12 May, 2022 | |
| Shawn Assad | Chief Accounting Officer | 973 | 12 May, 2022 |
| Kareem Saad | Chief Transformation Officer | 29,517 | 19 Mar, 2024 |
| Richard Miao | 753 | 26 Aug, 2022 | |
| James Coffin | President And COO | 694 | 03 Dec, 2021 |
| Emily M. Leproust | 21,276 | 23 Jun, 2025 | |
| Michael J Pellini | 519 | 18 Oct, 2022 | |
| Anthony Prentice | Chief Product Officer | 367 | 27 Jul, 2022 |
| Katherine Stueland | Chief Executive Officer | 6,344 | 11 Dec, 2025 |
| Kevin Feeley | Chief Financial Officer | 5,389 | 11 Dec, 2025 |
| Karen Ann White | Chief People Officer | 4,761 | 27 Jul, 2023 |
* Please note that the shares above only reflect shares from the fund portfolio and the institutional portfolio. Shares from the personal portfolio are excluded from this Institutional Ownership Page. See these insiders' latest transactions here on Insider Page.
| Transaction Date | Insider Name | Security Class | Transaction Type | Shares Traded | Price | Shares Remaining | Ownership | Code |
|---|---|---|---|---|---|---|---|---|
| 09 Dec, 2025 | Kevin Feeley | Class A Common Stock | A | 2,462 | $0.00 | 6,655 | D | M |
| 09 Dec, 2025 | Katherine Stueland | Class A Common Stock | A | 6,547 | $0.00 | 9,983 | D | M |
| 09 Dec, 2025 | Katherine Stueland | Class A Common Stock | D | 3,639 | $159.28 | 6,344 | D | S |
| 09 Dec, 2025 | Kevin Feeley | Class A Common Stock | D | 1,266 | $159.28 | 5,389 | D | S |
| 01 Dec, 2025 | Kevin Feeley | Class A Common Stock | A | 717 | $0.00 | 4,570 | D | M |
| 01 Dec, 2025 | Kevin Feeley | Class A Common Stock | D | 377 | $162.54 | 4,193 | D | S |
| 24 Nov, 2025 | Joshua Ruch | Class A Common Stock | D | 201 | $158.40 | 14,644 | I | S |
| 24 Nov, 2025 | Joshua Ruch | Class A Common Stock | D | 625 | $159.28 | 14,019 | I | S |
| 24 Nov, 2025 | Joshua Ruch | Class A Common Stock | D | 889 | $160.45 | 13,130 | I | S |
| 24 Nov, 2025 | Joshua Ruch | Class A Common Stock | D | 1,117 | $161.16 | 12,013 | I | S |
| 24 Nov, 2025 | Joshua Ruch | Class A Common Stock | D | 72 | $162.04 | 11,941 | I | S |
| 24 Nov, 2025 | Joshua Ruch | Class A Common Stock | D | 407 | $158.40 | 29,731 | I | S |
| 24 Nov, 2025 | Joshua Ruch | Class A Common Stock | D | 1,268 | $159.28 | 28,463 | I | S |
| 24 Nov, 2025 | Joshua Ruch | Class A Common Stock | D | 1,805 | $160.45 | 26,658 | I | S |
| 24 Nov, 2025 | Joshua Ruch | Class A Common Stock | D | 2,268 | $161.16 | 24,390 | I | S |
| 24 Nov, 2025 | Joshua Ruch | Class A Common Stock | D | 147 | $162.04 | 24,243 | I | S |
| 24 Nov, 2025 | Joshua Ruch | Class A Common Stock | D | 2,016 | $158.40 | 147,268 | I | S |
| 24 Nov, 2025 | Joshua Ruch | Class A Common Stock | D | 6,279 | $159.28 | 140,989 | I | S |
| 24 Nov, 2025 | Joshua Ruch | Class A Common Stock | D | 8,944 | $160.45 | 132,045 | I | S |
| 24 Nov, 2025 | Joshua Ruch | Class A Common Stock | D | 11,234 | $161.16 | 120,811 | I | S |