Ventyx Biosciences, Inc. (VTYX) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

71,071,333Shares Outstanding

1,088,343Shares held by institutions

$15,182,385Value of institutional holdings

73.46%Institutional ownership %

46.87%Shares Changed QoQ

136No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

The institutional landscape for Ventyx Biosciences, Inc. (NASDAQ:VTYX) includes 136 filers as of the latest reporting cycle ending December 2025.

The collective stake of institutional investors in Ventyx Biosciences moved to 73.5% in December 2025, a shift up from the 61.4% reported for September 2025.
The company experienced a 46.87% quarterly change in institutional shares held, alongside an increase of 9.68% in total owners annually.
Among the 136 institutional holders of Ventyx Biosciences, 82 added to their stakes while 38 trimmed their positions and 16 held steady.
Collectively, institutional investors increased their stake in Ventyx Biosciences to 52.21Mn shares as of December 2025, a change that is up by 16.66Mn shares quarter on quarter and down 2.24Mn shares year over year.
The top institutional stake in Ventyx Biosciences as of December 31, 2025 belongs to Affinity Asset Advisors, LLC, which owns 6.48Mn shares, or 9.12% of the company.
Among the most significant buyers of Ventyx Biosciences during December 2025 were MORGAN STANLEY (4.05Mn), Affinity Asset Advisors, LLC (2.56Mn), BlackRock, Inc. (1.96Mn), BRAIDWELL LP (1.92Mn), MPM BioImpact LLC (1.64Mn).
Leading sellers of Ventyx Biosciences stock in December 2025 included Point72 Asset Management, L.P. (2.15Mn), SECTORAL ASSET MANAGEMENT INC (1.01Mn), JPMORGAN CHASE & CO (742.64K), MILLENNIUM MANAGEMENT LLC (661.88K), UBS Group AG (459.08K).
The top 10 institutional holders of Ventyx Biosciences for the quarter ending December 2025 included Affinity Asset Advisors, LLC (6.48Mn), MORGAN STANLEY (4.29Mn), VANGUARD GROUP INC (3.94Mn), BlackRock, Inc. (3.14Mn), TANG CAPITAL MANAGEMENT LLC (2.81Mn), BAKER BROS. ADVISORS LP (2.35Mn), BRAIDWELL LP (1.92Mn), D. E. Shaw & Co., Inc. (1.67Mn), MPM BioImpact LLC (1.64Mn), CITADEL ADVISORS LLC (1.56Mn).

136 Institutional Holders

1,088,343 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
Affinity Asset Advisors, LLC	31 Dec, 2025	6,484,558	2,560,143	65.24%	$58,555,559.00
MORGAN STANLEY	31 Dec, 2025	4,292,951	4,049,194	1,661.16%	$38,765,348.00
VANGUARD GROUP INC	31 Dec, 2025	3,943,566	173,569	4.60%	$35,610,400.00
BlackRock, Inc.	31 Dec, 2025	3,142,440	1,959,200	165.58%	$28,376,233.00
TANG CAPITAL MANAGEMENT LLC	31 Dec, 2025	2,814,000	-286,000	-9.23%	$25,410,420.00
BAKER BROS. ADVISORS LP	31 Dec, 2025	2,349,280	1,326,150	129.62%	$21,213,998.00
BRAIDWELL LP	31 Dec, 2025	1,920,255	1,920,255	0.00%	$17,339,903.00
D. E. Shaw & Co., Inc.	31 Dec, 2025	1,665,474	1,142,786	218.64%	$15,039,230.00
MPM BioImpact LLC	31 Dec, 2025	1,639,061	1,639,061	0.00%	$14,800,721.00
CITADEL ADVISORS LLC	31 Dec, 2025	1,563,611	-316,378	-16.83%	$14,119,407.00
JANE STREET GROUP, LLC	31 Dec, 2025	1,325,067	917,663	225.25%	$11,965,355.00
GOLDMAN SACHS GROUP INC	31 Dec, 2025	1,257,602	850,691	209.06%	$11,356,146.00
Connor, Clark & Lunn Investment Management Ltd.	31 Dec, 2025	1,203,997	144,174	13.60%	$10,872,093.00
SUSQUEHANNA INTERNATIONAL GROUP, LLP	31 Dec, 2025	1,118,275	438,297	64.46%	$10,098,023.00
Point72 Asset Management, L.P.	31 Dec, 2025	1,056,520	-2,153,125	-67.08%	$9,540,376.00
683 Capital Management, LLC	31 Dec, 2025	1,040,000	40,000	4.00%	$9,391,200.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	989,917	-661,877	-40.07%	$8,938,951.00
ACADIAN ASSET MANAGEMENT LLC	31 Dec, 2025	773,512	69,712	9.91%	$6,978.00
DIMENSIONAL FUND ADVISORS LP	31 Dec, 2025	742,544	321,203	76.23%	$6,702,415.00
BALYASNY ASSET MANAGEMENT L.P.	31 Dec, 2025	735,711	735,711	0.00%	$6,643,470.00

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