Vistagen Therapeutics, Inc. (VTGN) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

41,997,778Shares Outstanding

5,762,133Shares held by institutions

$3,053,930Value of institutional holdings

32.19%Institutional ownership %

-1.63%Shares Changed QoQ

53No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

The institutional landscape for Vistagen Therapeutics, Inc. (NASDAQ:VTGN) includes 53 filers as of the latest reporting cycle ending December 2025.

The percentage of Vistagen Therapeutics owned by institutions changed from 72.6% in September 2025 to 32.2% in December 2025, marking a slight down trend.
In percentage terms, this reflects as a holdings change of -1.63% quarter on quarter, and a decrease of 3.64% year over year.
Among the 53 institutional holders of Vistagen Therapeutics, 31 added to their stakes while 14 trimmed their positions and 8 held steady.
The aggregate institutional position in Vistagen Therapeutics now stands at 13.52Mn shares as of December 2025, after investors decreased their holdings (down by 224.06K shares quarter on quarter which is down 2.19Mn shares year over year).
With 3.06Mn shares, ORBIMED ADVISORS LLC commands the largest institutional position in Vistagen Therapeutics as of December 31, 2025, equating to 7.29% of the company.
Among the most significant buyers of Vistagen Therapeutics during December 2025 were ADAR1 Capital Management, LLC (630.51K), LUMINUS MANAGEMENT LLC (350.00K), JANE STREET GROUP, LLC (289.64K), SUSQUEHANNA INTERNATIONAL GROUP, LLP (249.19K), MILLENNIUM MANAGEMENT LLC (176.37K).
Leading sellers of Vistagen Therapeutics stock in December 2025 included STEMPOINT CAPITAL LP (1.87Mn), JPMORGAN CHASE & CO (271.81K), RENAISSANCE TECHNOLOGIES LLC (261.22K), DIADEMA PARTNERS LP (243.49K), TWO SIGMA INVESTMENTS, LP (93.84K).
The top 10 institutional holders of Vistagen Therapeutics for the quarter ending December 2025 included ORBIMED ADVISORS LLC (3.06Mn), TCG Crossover Management, LLC (2.68Mn), VANGUARD GROUP INC (1.82Mn), ADAR1 Capital Management, LLC (743.58K), STEMPOINT CAPITAL LP (616.75K), JANE STREET GROUP, LLC (606.83K), BlackRock, Inc. (422.76K), GEODE CAPITAL MANAGEMENT, LLC (352.84K), LUMINUS MANAGEMENT LLC (350.00K), SUSQUEHANNA INTERNATIONAL GROUP, LLP (334.79K).

53 Institutional Holders

5,762,133 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
ORBIMED ADVISORS LLC	31 Dec, 2025	3,060,000	0	0.00%	$2,025,414.00
TCG Crossover Management, LLC	31 Dec, 2025	2,676,580	0	0.00%	$1,771,628.00
VANGUARD GROUP INC	31 Dec, 2025	1,824,738	137,003	8.12%	$1,207,977.00
ADAR1 Capital Management, LLC	31 Dec, 2025	743,575	630,513	557.67%	$492,172.00
STEMPOINT CAPITAL LP	31 Dec, 2025	616,749	-1,871,936	-75.22%	$142,086.00
JANE STREET GROUP, LLC	31 Dec, 2025	606,827	289,644	91.32%	$401,658.00
BlackRock, Inc.	31 Dec, 2025	422,759	-369	-0.09%	$279,824.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	352,836	54,556	18.29%	$233,605.00
LUMINUS MANAGEMENT LLC	31 Dec, 2025	350,000	350,000	0.00%	$231,665.00
SUSQUEHANNA INTERNATIONAL GROUP, LLP	31 Dec, 2025	334,786	249,192	291.13%	$221,595.00
AdvisorShares Investments LLC	31 Dec, 2025	250,188	43,190	20.86%	$165,599.00
DIADEMA PARTNERS LP	31 Dec, 2025	206,500	-243,489	-54.11%	$136,682.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	197,045	176,369	853.01%	$130,424.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	195,570	-93,839	-32.42%	$129,448.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	160,791	-261,221	-61.90%	$106,428.00
DIMENSIONAL FUND ADVISORS LP	31 Dec, 2025	151,874	83,857	123.29%	$100,629.00
TWO SIGMA ADVISERS, LP	31 Dec, 2025	137,732	-19,300	-12.29%	$91,165.00
BOOTHBAY FUND MANAGEMENT, LLC	31 Dec, 2025	134,571	-62,453	-31.70%	$89,073.00
STATE STREET CORP	31 Dec, 2025	121,114	24,256	25.04%	$80,165.00
GROUP ONE TRADING LLC	31 Dec, 2025	106,137	77,209	266.90%	$70,252.00

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