UNITED THERAPEUTICS Corp (UTHR) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

47,287,671Shares Outstanding

4,374,565Shares held by institutions

$2,110,377,647Value of institutional holdings

91.60%Institutional ownership %

1.54%Shares Changed QoQ

398No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

UNITED THERAPEUTICS Corp (NASDAQ:UTHR) currently has 777 active institutional owners and shareholders as of today (December 2025), that have filed 13F forms with the Securities Exchange Commission (SEC).

The collective stake of institutional investors in United Therapeutics moved to 84.5% in December 2025, a shift down from the 87.0% reported for September 2025.
On a quarter-over-quarter basis, institutional holdings shifted by 4.48%, with a year-over-year an increase of 17.37% in the count of filers.
The latest 13F cycle for United Therapeutics reveals that of 777 total investors, 442 funds grew their exposure, whereas 244 reduced theirs and 91 made no changes.
Collectively, institutional investors increased their stake in United Therapeutics to 40.69Mn shares as of December 2025, a change that is up by 1.75Mn shares quarter on quarter and down 3.54Mn shares year over year.
With 5.17Mn shares, BlackRock, Inc. commands the largest institutional position in United Therapeutics as of December 31, 2025, equating to 10.74% of the company.
Among the most significant buyers of United Therapeutics during December 2025 were WELLINGTON MANAGEMENT GROUP LLP (1.04Mn), NORGES BANK (602.19K), Avoro Capital Advisors LLC (583.84K), JANUS HENDERSON GROUP PLC (341.38K), BAILLIE GIFFORD & CO (323.02K).
Leading sellers of United Therapeutics stock in December 2025 included CITIGROUP INC (367.06K), LSV ASSET MANAGEMENT (278.64K), RENAISSANCE TECHNOLOGIES LLC (264.13K), VANGUARD GROUP INC (242.59K), MILLENNIUM MANAGEMENT LLC (206.60K).
The top 10 institutional holders of United Therapeutics for the quarter ending December 2025 included BlackRock, Inc. (5.17Mn), VANGUARD GROUP INC (4.18Mn), Avoro Capital Advisors LLC (2.61Mn), WELLINGTON MANAGEMENT GROUP LLP (2.44Mn), RENAISSANCE TECHNOLOGIES LLC (1.91Mn), STATE STREET CORP (1.84Mn), AQR CAPITAL MANAGEMENT LLC (1.28Mn), GEODE CAPITAL MANAGEMENT, LLC (1.19Mn), JANUS HENDERSON GROUP PLC (796.10K), ASSETMARK, INC (634.96K).

777 Institutional Holders

4,374,565 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	5,170,766	-182,230	-3.40%	$2,519,455,839.00
VANGUARD GROUP INC	31 Dec, 2025	4,176,016	-242,594	-5.49%	$2,034,763,797.00
Avoro Capital Advisors LLC	31 Dec, 2025	2,606,060	583,838	28.87%	$1,269,802,735.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	2,441,492	1,042,711	74.54%	$1,189,616,979.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	1,909,259	-264,133	-12.15%	$930,286,448.00
STATE STREET CORP	31 Dec, 2025	1,842,411	-80,198	-4.17%	$897,714,760.00
AQR CAPITAL MANAGEMENT LLC	31 Dec, 2025	1,281,699	295,221	29.93%	$624,507,810.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	1,193,064	-56,596	-4.53%	$580,238,360.00
JANUS HENDERSON GROUP PLC	31 Dec, 2025	796,101	341,383	75.08%	$387,801,106.00
ASSETMARK, INC	31 Dec, 2025	634,956	-10,952	-1.70%	$309,382,109.00
NORGES BANK	31 Dec, 2025	602,191	602,191	0.00%	$293,417,565.00
DIMENSIONAL FUND ADVISORS LP	31 Dec, 2025	528,210	15,394	3.00%	$257,405,220.00
Caption Management, LLC	31 Dec, 2025	437,681	-165,238	-27.41%	$213,260,067.00
DEERFIELD MANAGEMENT COMPANY, L.P.	31 Dec, 2025	425,993	0	0.00%	$207,565,089.00
JANE STREET GROUP, LLC	31 Dec, 2025	425,120	77,744	22.38%	$207,139,720.00
NORTHERN TRUST CORP	31 Dec, 2025	418,427	-28,591	-6.40%	$203,878,557.00
LSV ASSET MANAGEMENT	31 Dec, 2025	408,065	-278,645	-40.58%	$198,830.00
FMR LLC	31 Dec, 2025	403,830	153,499	61.32%	$196,766,016.00
MORGAN STANLEY	31 Dec, 2025	389,275	-49,529	-11.29%	$189,675,140.00
Bank of New York Mellon Corp	31 Dec, 2025	333,629	-17,826	-5.07%	$162,560,825.00

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