Talphera, Inc. (TLPH) Institutional Ownership

Institutions by Trading Activity

40,327,273Shares Outstanding

10Shares held by institutions

$8Value of institutional holdings

13.42%Institutional ownership %

11.23%Shares Changed QoQ

6No. of institutional investors

According to SEC filings for the period ending December 2025, Talphera, Inc. (NASDAQ:TLPH) is held by 6 institutional firms.

The percentage of Talphera owned by institutions changed from 44.7% in September 2025 to 13.4% in December 2025, marking a slight down trend.
On a quarter-over-quarter basis, institutional holdings shifted by 11.23%, with a year-over-year a decrease of 82.86% in the count of filers.
Of these 6 institutional investors, 2 increased their holdings in Talphera, while 3 of them reduced positions, and 1 investors maintained their exposure.
This class of investors increased its holdings in Talphera to 5.41Mn shares for the 13F-cycle ending December 2025, up by 546.72K shares quarter on quarter, and up 1.34Mn shares year over year.
The top institutional stake in Talphera as of December 31, 2025 belongs to AIGH Capital Management LLC, which owns 4.66Mn shares, or 11.56% of the company.
Among the most significant buyers of Talphera during December 2025 were VANGUARD GROUP INC (377.45K), AIGH Capital Management LLC (206.96K).
Leading sellers of Talphera stock in December 2025 included UBS Group AG (20.83K), Values First Advisors, Inc. (16.67K), SBI Securities Co., Ltd. (175).
The top 6 institutional holders of Talphera for the quarter ending December 2025 included AIGH Capital Management LLC (4.66Mn), VANGUARD GROUP INC (663.68K), Values First Advisors, Inc. (81.21K), UBS Group AG (6.82K), SBI Securities Co., Ltd. (78), Dogwood Wealth Management LLC (10).

10 Total Shares Held

Rows:

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
AIGH Capital Management LLC	30 Sep, 2025	4,454,545	4,454,545	0.00%	$3,978,800.00
Rosalind Advisors, Inc.	30 Sep, 2025	4,385,757	2,381,818	118.86%	$3,917,358.00
Rock Springs Capital Management LP	30 Sep, 2025	3,589,186	3,272,726	1,034.17%	$3,205,861.00
Nantahala Capital Management, LLC	30 Sep, 2025	3,492,519	1,500,000	75.28%	$3,119,518.00
Bleichroeder LP	30 Sep, 2025	881,166	454,545	106.55%	$787,057.00
VANGUARD GROUP INC	30 Sep, 2025	286,229	204,871	251.81%	$256,748.00
Caption Management, LLC	30 Sep, 2025	250,000	250,000	0.00%	$223,300.00
GEODE CAPITAL MANAGEMENT, LLC	30 Sep, 2025	165,693	299	0.18%	$148,698.00
Dauntless Investment Group, LLC	30 Sep, 2025	100,000	100,000	0.00%	$89,320.00
Values First Advisors, Inc.	30 Sep, 2025	97,882	-1,329	-1.34%	$87,429.00
BlackRock, Inc.	30 Sep, 2025	91,548	0	0.00%	$81,771.00
RENAISSANCE TECHNOLOGIES LLC	30 Sep, 2025	50,214	27,688	122.92%	$44,851.00
Virtu Financial LLC	30 Sep, 2025	32,811	32,811	0.00%	$29.00
GROUP ONE TRADING LLC	30 Sep, 2025	30,415	30,400	202,666.67%	$27,285.00
UBS Group AG	30 Sep, 2025	27,650	27,628	125,581.82%	$24,692.00
Mariner, LLC	30 Sep, 2025	25,000	25,000	0.00%	$22,330.00
STATE STREET CORP	30 Sep, 2025	22,182	0	0.00%	$19,899.00
Onyx Bridge Wealth Group LLC	30 Sep, 2025	11,500	1,200	11.65%	$10,272.00
NORTHERN TRUST CORP	30 Sep, 2025	10,891	0	0.00%	$9,728.00
PFG Investments, LLC	30 Sep, 2025	10,000	10,000	0.00%	$8,932.00

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