Talphera, Inc. (TLPH) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

32,600,000Shares Outstanding

8,080,208Shares held by institutions

$6,383,364Value of institutional holdings

67.00%Institutional ownership %

21.53%Shares Changed QoQ

38No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Recent 13F filings as of December 2025 show that 38 institutional investors hold a position in Talphera, Inc. (NASDAQ:TLPH).

Institutional ownership in Talphera edged up to 67.0% in December 2025, compared to 55.3% in September 2025.
Quarterly data indicates a 21.53% shift in institutional share volume, and the annual owner count reflects an increase of 8.57%.
Among the 38 institutional holders of Talphera, 22 added to their stakes while 6 trimmed their positions and 10 held steady.
The aggregate institutional position in Talphera now stands at 21.84Mn shares as of December 2025, after investors increased their holdings (up by 3.87Mn shares quarter on quarter which is up 17.76Mn shares year over year).
The top institutional stake in Talphera as of December 31, 2025 belongs to AIGH Capital Management LLC, which owns 4.66Mn shares, or 14.30% of the company.
Among the most significant buyers of Talphera during December 2025 were Empery Asset Management, LP (1.33Mn), CANTOR FITZGERALD, L. P. (577.49K), Caption Management, LLC (549.60K), Dauntless Investment Group, LLC (479.32K), VANGUARD GROUP INC (377.45K).
Leading sellers of Talphera stock in December 2025 included Rosalind Advisors, Inc. (806.48K), UBS Group AG (20.83K), Values First Advisors, Inc. (16.67K), Tower Research Capital LLC (TRC) (3.36K), SBI Securities Co., Ltd. (175).
The top 10 institutional holders of Talphera for the quarter ending December 2025 included AIGH Capital Management LLC (4.66Mn), Rock Springs Capital Management LP (3.59Mn), Rosalind Advisors, Inc. (3.58Mn), Nantahala Capital Management, LLC (3.49Mn), Empery Asset Management, LP (1.33Mn), Bleichroeder LP (881.17K), Caption Management, LLC (799.60K), VANGUARD GROUP INC (663.68K), Dauntless Investment Group, LLC (579.32K), CANTOR FITZGERALD, L. P. (577.49K).

38 Institutional Holders

8,080,208 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
AIGH Capital Management LLC	31 Dec, 2025	4,661,502	206,957	4.65%	$5,314,112.00
Rock Springs Capital Management LP	31 Dec, 2025	3,589,186	0	0.00%	$4,091,672.00
Rosalind Advisors, Inc.	31 Dec, 2025	3,579,273	-806,484	-18.39%	$4,080,371.00
Nantahala Capital Management, LLC	31 Dec, 2025	3,492,519	0	0.00%	$3,981,472.00
Empery Asset Management, LP	31 Dec, 2025	1,333,497	1,333,497	0.00%	$1,520,187.00
Bleichroeder LP	31 Dec, 2025	881,166	0	0.00%	$1,004,529.00
Caption Management, LLC	31 Dec, 2025	799,600	549,600	219.84%	$911,544.00
VANGUARD GROUP INC	31 Dec, 2025	663,677	377,448	131.87%	$756,593.00
Dauntless Investment Group, LLC	31 Dec, 2025	579,320	479,320	479.32%	$660,425.00
CANTOR FITZGERALD, L. P.	31 Dec, 2025	577,490	577,490	0.00%	$658,339.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	342,987	177,294	107.00%	$391,071.00
JANE STREET GROUP, LLC	31 Dec, 2025	269,938	269,938	0.00%	$307,730.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	257,380	207,166	412.57%	$293,413.00
DIADEMA PARTNERS LP	31 Dec, 2025	136,923	136,923	0.00%	$156,092.00
BlackRock, Inc.	31 Dec, 2025	91,548	0	0.00%	$104,365.00
SIMPLEX TRADING, LLC	31 Dec, 2025	85,799	84,572	6,892.58%	$97,810.00
Values First Advisors, Inc.	31 Dec, 2025	81,208	-16,674	-17.03%	$92,577.00
CITADEL ADVISORS LLC	31 Dec, 2025	76,445	76,445	0.00%	$87,147.00
Mariner, LLC	31 Dec, 2025	58,000	33,000	132.00%	$66,120.00
GROUP ONE TRADING LLC	31 Dec, 2025	57,173	26,758	87.98%	$65,177.00

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