Sutro Biopharma, Inc. (STRO) Institutional Ownership

Institutions by Trading Activity

8,486,986Shares Outstanding

5,696,383Shares held by institutions

$166,106,528Value of institutional holdings

67.12%Institutional ownership %

1,864.32%Shares Changed QoQ

61No. of institutional investors

Sutro Biopharma, Inc. (NASDAQ:STRO) appears in 61 institutional 13F filings for the quarter ending December 2025.

Their combined ownership stood at 66.9% of outstanding shares in December 2025, up from 63.1% in September 2025.
They increased total shares held in STRO by 1858.92% quarter over quarter, and investors in Sutro Biopharma decreased 50.41% from a year ago.
Among the 61 funds, 58 bought more Sutro Biopharma shares, 1 sold down, and 2 held their ground.
In total, institutional investors held 5.68Mn shares in Sutro Biopharma as of December 2025, up by 5.39Mn shares quarter on quarter, and down 877.81K shares year over year.
Affinity Asset Advisors, LLC holds the largest position in STRO at 748.38K shares as of December 31, 2025, or 8.82% of shares outstanding.
Top purchasers of STRO stock for the quarter ending December 2025 included Affinity Asset Advisors, LLC (748.38K), Kynam Capital Management, LP (479.59K), MILLENNIUM MANAGEMENT LLC (418.2K), VANGUARD GROUP INC (375.79K), ACADIAN ASSET MANAGEMENT LLC (337.95K).
The largest sales of STRO for the quarter ending December 2025 came from EverSource Wealth Advisors, LLC (14).
Sutro Biopharma's 10 largest shareholders as of December 2025 include Affinity Asset Advisors, LLC (748.38K), Kynam Capital Management, LP (479.59K), MILLENNIUM MANAGEMENT LLC (418.2K), VANGUARD GROUP INC (375.79K), ACADIAN ASSET MANAGEMENT LLC (337.95K), Velan Capital Investment Management LP (312.0K), Merck & Co., Inc. (272.35K), Vestal Point Capital, LP (243.0K), BALYASNY ASSET MANAGEMENT L.P. (230.05K), Samsara BioCapital, LLC (204.5K) per Business Quant data.

5,696,383 Total Shares Held

Rows:

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
Affinity Asset Advisors, LLC	31 Dec, 2025	748,382	748,382	0.00%	$8,658,780.00
Kynam Capital Management, LP	31 Dec, 2025	479,590	479,590	0.00%	$5,548,856.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	418,196	418,196	0.00%	$4,838,528.00
VANGUARD GROUP INC	31 Dec, 2025	375,786	375,786	0.00%	$4,347,844.00
ACADIAN ASSET MANAGEMENT LLC	31 Dec, 2025	337,953	337,953	0.00%	$3,908.00
Velan Capital Investment Management LP	31 Dec, 2025	312,000	312,000	0.00%	$3,609,840.00
Merck & Co., Inc.	31 Dec, 2025	272,351	0	0.00%	$3,151,101.00
Vestal Point Capital, LP	31 Dec, 2025	243,000	243,000	0.00%	$2,811,510.00
BALYASNY ASSET MANAGEMENT L.P.	31 Dec, 2025	230,049	230,049	0.00%	$2,661,667.00
Samsara BioCapital, LLC	31 Dec, 2025	204,503	204,503	0.00%	$2,366,100.00
ADAGE CAPITAL PARTNERS GP, L.L.C.	31 Dec, 2025	200,000	200,000	0.00%	$2,314,000.00
Eversept Partners, LP	31 Dec, 2025	193,571	193,571	0.00%	$2,239,616.00
Opaleye Management Inc.	31 Dec, 2025	190,671	190,671	0.00%	$2,206,063.00
Point72 Asset Management, L.P.	31 Dec, 2025	179,088	179,088	0.00%	$2,072,048.00
TANG CAPITAL MANAGEMENT LLC	31 Dec, 2025	139,617	139,617	0.00%	$1,615,369.00
ADAR1 Capital Management, LLC	31 Dec, 2025	134,154	134,154	0.00%	$1,552,162.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	122,865	122,865	0.00%	$1,421,548.00
BlackRock, Inc.	31 Dec, 2025	117,437	117,437	0.00%	$1,358,746.00
GSA CAPITAL PARTNERS LLP	31 Dec, 2025	89,067	89,067	0.00%	$1,031.00
MARSHALL WACE, LLP	31 Dec, 2025	85,615	85,615	0.00%	$990,565.00

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