| # | Insider | Position | Direct | Indirect | Total | Share of Insiders | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Inc. Biogen | TenPercentOwner | 0 | 17,652,466 | 17,652,466 | 76.1% | 28 Sep, 2023 |
| 2 | Sandy Macrae | President, Ceo And Director | 1,895,043 | 0 | 1,895,043 | 8.2% | 27 May, 2026 |
| 3 | Prathyusha Duraibabu | Principal Financial Officer | 660,042 | 0 | 660,042 | 2.8% | 26 Jan, 2026 |
| 4 | Scott B. Willoughby | Svp, Chief Legal Officer, Secy | 647,370 | 0 | 647,370 | 2.8% | 27 May, 2026 |
| 5 | Nathalie Dubois-Stringfellow | Svp Chief Development Officer | 328,733 | 0 | 328,733 | 1.4% | 27 May, 2026 |
| 6 | Nikunj Jain | Principal Accounting Officer | 237,211 | 0 | 237,211 | 1.0% | 26 Feb, 2026 |
| 7 | David Mark Mcclung | Evp, Chief Operating Officer | 212,471 | 0 | 212,471 | 0.9% | 28 Nov, 2023 |
| 8 | Amy Pooler | Vp, Head Of Research | 193,923 | 0 | 193,923 | 0.8% | 27 Aug, 2024 |
| 9 | Rolf Andrew Ramelmeier | Evp, Technical Operations | 171,467 | 0 | 171,467 | 0.7% | 30 May, 2023 |
| 10 | Jason D. Fontenot | Svp, Chief Scientific Officer | 136,270 | 0 | 136,270 | 0.6% | 28 Nov, 2023 |
| 11 | Gregory D Davis | Head Of Research Technology | 113,654 | 0 | 113,654 | 0.5% | 27 May, 2026 |
| 12 | H Stewart Parker | Director | 112,600 | 0 | 112,600 | 0.5% | 16 Jun, 2025 |
| 13 | Karen L. Smith | Director | 102,100 | 0 | 102,100 | 0.4% | 16 Jun, 2025 |
| 14 | Kenneth J. Hillan | Director | 99,600 | 0 | 99,600 | 0.4% | 16 Jun, 2025 |
| 15 | Robert Carey | Director | 99,600 | 0 | 99,600 | 0.4% | 16 Jun, 2025 |
| 16 | James R Meyers | Director | 99,600 | 0 | 99,600 | 0.4% | 16 Jun, 2025 |
| 17 | John Markels | Director | 96,384 | 0 | 96,384 | 0.4% | 16 Jun, 2025 |
| 18 | Margaret A Horn | Director | 82,650 | 0 | 82,650 | 0.4% | 16 Jun, 2025 |
| 19 | Courtney Beers | Director | 82,650 | 0 | 82,650 | 0.4% | 16 Jun, 2025 |
| 20 | Robert J. Schott | Svp, Head Of Development | 75,537 | 0 | 75,537 | 0.3% | 01 Mar, 2022 |
| 21 | Joseph S Zakrzewski | Director | 60,700 | 0 | 60,700 | 0.3% | 01 Mar, 2022 |
| 22 | Saira Ramasastry | Director | 35,700 | 0 | 35,700 | 0.2% | 01 Mar, 2022 |
Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.
| Date | Insider | Position | Transaction | Shares | Price | Value | Shares Held After | Ownership |
|---|---|---|---|---|---|---|---|---|
| 25 May, 2026 | Gregory D Davis | Head Of Research Technology | Disposed F | 1,630 | $0.17 | $284 | 113,654 | Direct |
| 25 May, 2026 | Nathalie Dubois-Stringfellow | Svp Chief Development Officer | Disposed F | 4,036 | $0.17 | $703 | 328,733 | Direct |
| 25 May, 2026 | Sandy Macrae | President, Ceo And Director | Disposed F | 12,613 | $0.17 | $2.20K | 1,895,043 | Direct |
| 25 May, 2026 | Scott B. Willoughby | Svp, Chief Legal Officer, Secy | Disposed F | 4,036 | $0.17 | $703 | 647,370 | Direct |
| 22 Apr, 2026 | Gregory D Davis | Head Of Research Technology | Disposed S | 69,827 | $0.25 | $17.69K | 115,284 | Direct |
| 01 Apr, 2026 | Nathalie Dubois-Stringfellow | Svp Chief Development Officer | Acquired A | 800,000 | $0.00 | $0 | 800,000 | Direct |
| 01 Apr, 2026 | Nikunj Jain | Principal Accounting Officer | Acquired A | 225,000 | $0.00 | $0 | 225,000 | Direct |
| 01 Apr, 2026 | Sandy Macrae | President, Ceo And Director | Acquired A | 2,500,000 | $0.00 | $0 | 2,500,000 | Direct |
| 01 Apr, 2026 | Gregory D Davis | Head Of Research Technology | Acquired A | 225,000 | $0.00 | $0 | 225,000 | Direct |
| 01 Apr, 2026 | Scott B. Willoughby | Svp, Chief Legal Officer, Secy | Acquired A | 800,000 | $0.00 | $0 | 800,000 | Direct |
| 24 Feb, 2026 | Scott B. Willoughby | Svp, Chief Legal Officer, Secy | Disposed F | 1,650 | $0.47 | $780 | 663,760 | Direct |
| 24 Feb, 2026 | Sandy Macrae | President, Ceo And Director | Disposed F | 5,291 | $0.47 | $2.50K | 1,941,293 | Direct |
| 24 Feb, 2026 | Nathalie Dubois-Stringfellow | Svp Chief Development Officer | Disposed F | 2,063 | $0.47 | $975 | 691,065 | Direct |
| 24 Feb, 2026 | Gregory D Davis | Head Of Research Technology | Disposed F | 832 | $0.47 | $393 | 190,230 | Direct |
| 24 Feb, 2026 | Nikunj Jain | Principal Accounting Officer | Disposed F | 666 | $0.47 | $315 | 242,330 | Direct |
| 25 Feb, 2026 | Nikunj Jain | Principal Accounting Officer | Disposed F | 5,119 | $0.47 | $2.41K | 237,211 | Direct |
| 25 Feb, 2026 | Gregory D Davis | Head Of Research Technology | Disposed F | 5,119 | $0.47 | $2.41K | 185,111 | Direct |
| 25 Feb, 2026 | Scott B. Willoughby | Svp, Chief Legal Officer, Secy | Disposed F | 12,354 | $0.47 | $5.81K | 651,406 | Direct |
| 25 Feb, 2026 | Nathalie Dubois-Stringfellow | Svp Chief Development Officer | Disposed F | 12,354 | $0.47 | $5.81K | 678,711 | Direct |
| 25 Feb, 2026 | Sandy Macrae | President, Ceo And Director | Disposed F | 33,637 | $0.47 | $15.81K | 1,907,656 | Direct |