As of September 09, 2026, Quince Therapeutics's top three insider holders are Stephen S. Dominy (Chief Scientific Officer, 1.22Mn shares), Dirk Thye (Ceo And Cmo, 994.88K shares), Dirk Thye (Ceo And Chief Medical Officer, 843.94K shares).
| # | Insider | Position | Direct | Indirect | Total | Share of Insiders | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Dirk Thye | Ceo And Cmo | 1,098,941 | 739,885 | 1,838,826 | 36.3% | 11 Dec, 2025 |
| 2 | Stephen S. Dominy | Chief Scientific Officer | 0 | 1,217,086 | 1,217,086 | 24.1% | 12 Nov, 2021 |
| 3 | Philip S Low | Director | 455,309 | 63,974 | 519,283 | 10.3% | 23 May, 2022 |
| 4 | David Lamond | Director | 230,229 | 234,755 | 464,984 | 9.2% | 14 Dec, 2023 |
| 5 | Christopher P. Lowe | Interim Ceo, Coo Cfo | 265,000 | 0 | 265,000 | 5.2% | 04 Mar, 2022 |
| 6 | Charles S. Ryan | President | 252,470 | 0 | 252,470 | 5.0% | 20 Jun, 2025 |
| 7 | Leslie Holsinger | Evp, Preclinical Development | 148,080 | 0 | 148,080 | 2.9% | 08 Jun, 2022 |
| 8 | Michael J. Detke | Chief Medical Officer | 140,000 | 0 | 140,000 | 2.8% | 04 Mar, 2022 |
| 9 | Casey Lynch | Chief Executive Officer | 109,895 | 0 | 109,895 | 2.2% | 19 Nov, 2021 |
| 10 | Brendan Hannah | Cbo, Coo Cco | 65,837 | 0 | 65,837 | 1.3% | 06 Dec, 2025 |
| 11 | Karen L. Smith | Chief Medical Officer | 19,469 | 0 | 19,469 | 0.4% | 27 May, 2022 |
| 12 | Caryn Gordon Mcdowell | Chief Legal Adm. Officer | 12,250 | 0 | 12,250 | 0.2% | 08 Jun, 2022 |
| 13 | Luca Benatti | Director | 3,918 | 0 | 3,918 | 0.1% | 29 Dec, 2025 |
| 14 | Ted Monohon | Chief Accounting Officer Vp | 2,744 | 0 | 2,744 | 0.1% | 06 Mar, 2023 |
| 15 | Margaret Mcloughlin | Director | 800 | 0 | 800 | 0.0% | 09 Aug, 2023 |
Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.
| Date | Insider | Position | Transaction | Shares | Price | Value | Shares Held After | Ownership |
|---|---|---|---|---|---|---|---|---|
| 11 Jun, 2026 | Christopher J. Senner | Director | Acquired A | 2,700 | $0.00 | $0 | 14 | Direct |
| 11 Jun, 2026 | David Lamond | Director | Acquired A | 2,700 | $0.00 | $0 | 14 | Direct |
| 18 May, 2026 | Brigette Roberts | Chief Corp. Affairs Officer | Acquired A | 34,675 | — | — | 173 | Direct |
| 18 May, 2026 | Brigette Roberts | Chief Corp. Affairs Officer | Acquired A | 228,855 | — | — | 1,144 | Direct |
| 18 May, 2026 | Brigette Roberts | Chief Corp. Affairs Officer | Acquired A | 124,830 | — | — | 624 | Direct |
| 18 May, 2026 | Brigette Roberts | Chief Corp. Affairs Officer | Acquired A | 69,350 | — | — | 347 | Direct |
| 18 May, 2026 | Brigette Roberts | Chief Corp. Affairs Officer | Acquired A | 362,092 | — | — | 1,810 | Direct |
| 18 May, 2026 | Brigette Roberts | Chief Corp. Affairs Officer | Acquired A | 133,615 | — | — | 668 | Direct |
| 18 May, 2026 | Brigette Roberts | Chief Corp. Affairs Officer | Acquired A | 2,070,107 | — | — | 10,351 | Direct |
| 18 May, 2026 | Brigette Roberts | Chief Corp. Affairs Officer | Acquired A | 6,837,319 | — | — | 34,187 | Direct |
| 18 May, 2026 | Brigette Roberts | Chief Corp. Affairs Officer | Acquired A | 6,837,319 | — | — | 34,187 | Direct |
| 23 Jan, 2026 | Charles S. Ryan | President | Acquired A | 200,000 | $0.00 | $0 | 200,000 | Direct |
| 23 Jan, 2026 | Charles S. Ryan | President | Acquired A | 200,000 | $0.00 | $0 | 200,000 | Direct |
| 23 Jan, 2026 | Charles S. Ryan | President | Acquired A | 200,000 | $0.00 | $0 | 200,000 | Direct |
| 23 Jan, 2026 | Charles S. Ryan | President | Acquired A | 200,000 | $0.00 | $0 | 20,000 | Direct |
| 23 Jan, 2026 | Dirk Thye | Ceo And Cmo | Acquired A | 1,000,000 | $0.00 | $0 | 1,000,000 | Direct |
| 23 Jan, 2026 | Dirk Thye | Ceo And Cmo | Acquired A | 1,000,000 | $0.00 | $0 | 1,000,000 | Direct |
| 23 Jan, 2026 | Dirk Thye | Ceo And Cmo | Acquired A | 1,000,000 | $0.00 | $0 | 1,000,000 | Direct |
| 23 Jan, 2026 | Dirk Thye | Ceo And Cmo | Acquired A | 1,000,000 | $0.00 | $0 | 100,000 | Direct |
| 23 Jan, 2026 | Brendan Hannah | Cbo, Coo Cco | Disposed A | 365,000 | $0.00 | $0 | 36,500 | Direct |