Ptc Therapeutics, Inc. (PTCT) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

87,115,369Shares Outstanding

93,530,254Shares held by institutions

$6,702,378,002Value of institutional holdings

107.36%Institutional ownership %

13.07%Shares Changed QoQ

338No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Ptc Therapeutics, Inc. (NASDAQ:PTCT) showed up in the 13F filings of 337 institutional investors as of December 2025.

Collectively, these holders controlled 104.9% of Ptc Therapeutics's outstanding shares in December 2025, up from 97.5% in September 2025.
They increased total shares held in Ptc Therapeutics by 11.04% from last quarter, and the number of investors in PTCT increased 39.83% annually.
Of these 337 holders, 217 added to their stakes in Ptc Therapeutics, 93 trimmed positions, and 27 made no changes.
Altogether, these fund groups held 91.4Mn shares in PTCT by December 2025, up by 9.09Mn shares quarter on quarter, and up 9.23Mn shares year over year.
BlackRock, Inc. holds the largest position in PTCT at 12.78Mn shares as of December 31, 2025, or 14.67% of shares outstanding.
The biggest buyers of Ptc Therapeutics for the quarter ending December 2025 included BlackRock, Inc. (5.65Mn), Goldman Sachs Group Inc (1.17Mn), Janus Henderson Group Plc (1.08Mn), State Street Corp (1.07Mn), Toronto Dominion Bank (891.69K).
Top sellers of PTCT stock for the quarter ending December 2025 included Bank Of America Corp /De/ (1.6Mn), WELLINGTON MANAGEMENT GROUP LLP (1.05Mn), MILLENNIUM MANAGEMENT LLC (1.03Mn), Jpmorgan Chase & Co (625.83K), CITADEL ADVISORS LLC (576.57K).
Ptc Therapeutics's 10 largest shareholders as of December 2025 include BlackRock, Inc. (12.78Mn), VANGUARD GROUP INC (8.8Mn), RTW INVESTMENTS, LP (7.75Mn), Janus Henderson Group Plc (4.85Mn), State Street Corp (4.21Mn), Toronto Dominion Bank (4.14Mn), WELLINGTON MANAGEMENT GROUP LLP (3.87Mn), ARMISTICE CAPITAL, LLC (2.8Mn), Goldman Sachs Group Inc (2.05Mn), GEODE CAPITAL MANAGEMENT, LLC (2.02Mn) per Business Quant data.

338 Institutional Holders

93,530,254 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	12,779,065	5,648,258	79.21%	$970,697,777.00
VANGUARD GROUP INC	31 Dec, 2025	8,803,203	514,204	6.20%	$668,691,300.00
RTW INVESTMENTS, LP	31 Dec, 2025	7,746,415	0	0.00%	$588,417,683.00
Janus Henderson Group Plc	31 Dec, 2025	4,851,332	1,077,776	28.56%	$368,586,978.00
State Street Corp	31 Dec, 2025	4,206,126	1,071,343	34.18%	$319,497,331.00
Toronto Dominion Bank	31 Dec, 2025	4,138,215	891,690	27.47%	$314,338,811.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	3,867,380	-1,051,239	-21.37%	$293,766,184.00
ARMISTICE CAPITAL, LLC	31 Dec, 2025	2,801,869	-475,403	-14.51%	$212,829,969.00
Goldman Sachs Group Inc	31 Dec, 2025	2,046,182	1,169,773	133.47%	$155,427,984.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	2,016,062	65,184	3.34%	$153,164,342.00
D. E. Shaw & Co., Inc.	31 Dec, 2025	1,744,991	-429,617	-19.76%	$132,549,516.00
FMR LLC	31 Dec, 2025	1,681,216	69,441	4.31%	$127,705,195.00
Jefferies Financial Group Inc.	31 Dec, 2025	1,658,481	73,803	4.66%	$125,978,217.00
TANG CAPITAL MANAGEMENT LLC	31 Dec, 2025	1,500,000	0	0.00%	$113,940,000.00
Bank Of America Corp /De/	31 Dec, 2025	1,431,557	-1,602,515	-52.82%	$108,741,069.00
Franklin Resources Inc	31 Dec, 2025	1,286,685	129,651	11.21%	$97,736,593.00
CITADEL ADVISORS LLC	31 Dec, 2025	1,154,455	-576,570	-33.31%	$87,692,401.00
DRIEHAUS CAPITAL MANAGEMENT LLC	31 Dec, 2025	1,136,188	4,439	0.39%	$86,304,840.00
Point72 Asset Management, L.P.	31 Dec, 2025	1,128,551	-92,091	-7.54%	$85,724,734.00
Hood River Capital Management LLC	31 Dec, 2025	1,003,075	7,293	0.73%	$76,193,577.00

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