Ptc Therapeutics, Inc. (PTCT) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

87,818,107Shares Outstanding

9,592,851Shares held by institutions

$663,537,504Value of institutional holdings

102.54%Institutional ownership %

14.29%Shares Changed QoQ

327No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

According to SEC filings for the period ending December 2025, Ptc Therapeutics, Inc. (NASDAQ:PTCT) is held by 327 institutional firms.

These investors collectively held 102.5% of the company's total shares outstanding in December 2025, up from 94.5% in September 2025.
Quarterly data indicates a 14.29% shift in institutional share volume, and the annual owner count reflects an increase of 35.68%.
Among the 327 institutional holders of Ptc Therapeutics, 209 added to their stakes while 89 trimmed their positions and 29 held steady.
Collectively, institutional investors increased their stake in Ptc Therapeutics to 90.05Mn shares as of December 2025, a change that is up by 11.26Mn shares quarter on quarter and up 12.51Mn shares year over year.
BlackRock, Inc.'s holding of 12.78Mn shares as of December 31, 2025 makes it the primary institutional investor in Ptc Therapeutics, owning 14.55% of the stock.
Among the most significant buyers of Ptc Therapeutics during December 2025 were BlackRock, Inc. (5.65Mn), JANUS HENDERSON GROUP PLC (1.08Mn), STATE STREET CORP (1.07Mn), TORONTO DOMINION BANK (891.69K), BNP PARIBAS FINANCIAL MARKETS (808.51K).
Leading sellers of Ptc Therapeutics stock in December 2025 included WELLINGTON MANAGEMENT GROUP LLP (1.05Mn), MILLENNIUM MANAGEMENT LLC (1.03Mn), CITADEL ADVISORS LLC (576.57K), ARMISTICE CAPITAL, LLC (475.40K), D. E. Shaw & Co., Inc. (429.62K).
The top 10 institutional holders of Ptc Therapeutics for the quarter ending December 2025 included BlackRock, Inc. (12.78Mn), VANGUARD GROUP INC (8.80Mn), RTW INVESTMENTS, LP (7.75Mn), JANUS HENDERSON GROUP PLC (4.85Mn), STATE STREET CORP (4.21Mn), TORONTO DOMINION BANK (4.14Mn), WELLINGTON MANAGEMENT GROUP LLP (3.87Mn), ARMISTICE CAPITAL, LLC (2.80Mn), GEODE CAPITAL MANAGEMENT, LLC (2.02Mn), D. E. Shaw & Co., Inc. (1.74Mn).

327 Institutional Holders

9,592,851 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	12,779,065	5,648,258	79.21%	$970,697,777.00
VANGUARD GROUP INC	31 Dec, 2025	8,803,203	514,204	6.20%	$668,691,300.00
RTW INVESTMENTS, LP	31 Dec, 2025	7,746,415	0	0.00%	$588,417,683.00
JANUS HENDERSON GROUP PLC	31 Dec, 2025	4,851,332	1,077,776	28.56%	$368,586,978.00
STATE STREET CORP	31 Dec, 2025	4,206,126	1,071,343	34.18%	$319,497,331.00
TORONTO DOMINION BANK	31 Dec, 2025	4,138,215	891,690	27.47%	$314,338,811.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	3,867,380	-1,051,239	-21.37%	$293,766,184.00
ARMISTICE CAPITAL, LLC	31 Dec, 2025	2,801,869	-475,403	-14.51%	$212,829,969.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	2,016,062	65,184	3.34%	$153,164,342.00
D. E. Shaw & Co., Inc.	31 Dec, 2025	1,744,991	-429,617	-19.76%	$132,549,516.00
FMR LLC	31 Dec, 2025	1,681,216	69,441	4.31%	$127,705,195.00
Jefferies Financial Group Inc.	31 Dec, 2025	1,658,481	73,803	4.66%	$125,978,217.00
TANG CAPITAL MANAGEMENT LLC	31 Dec, 2025	1,500,000	0	0.00%	$113,940,000.00
BANK OF AMERICA CORP /DE/	31 Dec, 2025	1,431,557	-85,479	-5.63%	$108,741,069.00
FRANKLIN RESOURCES INC	31 Dec, 2025	1,286,685	129,651	11.21%	$97,736,593.00
CITADEL ADVISORS LLC	31 Dec, 2025	1,154,455	-576,570	-33.31%	$87,692,401.00
DRIEHAUS CAPITAL MANAGEMENT LLC	31 Dec, 2025	1,136,188	4,439	0.39%	$86,304,840.00
Point72 Asset Management, L.P.	31 Dec, 2025	1,128,551	-92,091	-7.54%	$85,724,734.00
GOLDMAN SACHS GROUP INC	31 Dec, 2025	1,023,091	146,682	16.74%	$77,713,992.00
Hood River Capital Management LLC	31 Dec, 2025	1,003,075	7,293	0.73%	$76,193,577.00

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