Personalis, Inc. (PSNL) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

90,216,667Shares Outstanding

23,682,834Shares held by institutions

$202,961,887Value of institutional holdings

76.17%Institutional ownership %

12.50%Shares Changed QoQ

118No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

A total of 118 institutions have reported a stake in Personalis, Inc. (NASDAQ:PSNL) as of December 2025, according to recent 13F filings with the SEC.

The percentage of Personalis owned by institutions changed from 71.8% in September 2025 to 76.2% in December 2025, marking a slight up trend.
The company experienced a 12.50% quarterly change in institutional shares held, alongside an increase of 11.32% in total owners annually.
The latest 13F cycle for Personalis reveals that of 118 total investors, 65 funds grew their exposure, whereas 37 reduced theirs and 16 made no changes.
Collectively, institutional investors increased their stake in Personalis to 68.72Mn shares as of December 2025, a change that is up by 7.64Mn shares quarter on quarter and up 17.16Mn shares year over year.
With 14.04Mn shares, Merck & Co., Inc. commands the largest institutional position in Personalis as of December 31, 2025, equating to 15.57% of the company.
Among the most significant buyers of Personalis during December 2025 were AMERIPRISE FINANCIAL INC (5.99Mn), Aberdeen Group plc (861.95K), PFM Health Sciences, LP (805.82K), NEXT CENTURY GROWTH INVESTORS LLC (624.36K), Portolan Capital Management, LLC (379.20K).
Leading sellers of Personalis stock in December 2025 included AIGH Capital Management LLC (992.10K), T. Rowe Price Investment Management, Inc. (945.54K), RENAISSANCE TECHNOLOGIES LLC (360.05K), BlackRock, Inc. (325.29K), GOLDMAN SACHS GROUP INC (231.51K).
The top 10 institutional holders of Personalis for the quarter ending December 2025 included Merck & Co., Inc. (14.04Mn), Lightspeed Management Company, L.L.C. (8.16Mn), ARK Investment Management LLC (7.88Mn), AMERIPRISE FINANCIAL INC (6.29Mn), BlackRock, Inc. (5.32Mn), VANGUARD GROUP INC (3.25Mn), Aberdeen Group plc (3.25Mn), AIGH Capital Management LLC (2.90Mn), T. Rowe Price Investment Management, Inc. (1.94Mn), KENNEDY CAPITAL MANAGEMENT LLC (1.71Mn).

118 Institutional Holders

23,682,834 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
Merck & Co., Inc.	31 Dec, 2025	14,044,943	0	0.00%	$111,797,746.00
Lightspeed Management Company, L.L.C.	31 Dec, 2025	8,160,734	0	0.00%	$64,959,443.00
ARK Investment Management LLC	31 Dec, 2025	7,879,087	-31,104	-0.39%	$62,717,533.00
AMERIPRISE FINANCIAL INC	31 Dec, 2025	6,287,151	5,988,126	2,002.55%	$50,045,728.00
BlackRock, Inc.	31 Dec, 2025	5,319,508	-325,291	-5.76%	$42,343,284.00
VANGUARD GROUP INC	31 Dec, 2025	3,253,797	247,387	8.23%	$25,900,225.00
Aberdeen Group plc	31 Dec, 2025	3,249,895	861,948	36.10%	$25,869,164.00
AIGH Capital Management LLC	31 Dec, 2025	2,900,000	-992,101	-25.49%	$23,084,000.00
T. Rowe Price Investment Management, Inc.	31 Dec, 2025	1,938,037	-945,539	-32.79%	$15,427.00
KENNEDY CAPITAL MANAGEMENT LLC	31 Dec, 2025	1,712,652	-222,426	-11.49%	$13,632,710.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	1,297,807	-35,734	-2.68%	$10,333,039.00
STATE STREET CORP	31 Dec, 2025	1,050,590	124,243	13.41%	$8,362,696.00
DIMENSIONAL FUND ADVISORS LP	31 Dec, 2025	983,174	9,519	0.98%	$7,826,162.00
PFM Health Sciences, LP	31 Dec, 2025	805,817	805,817	0.00%	$6,414,303.00
NEXT CENTURY GROWTH INVESTORS LLC	31 Dec, 2025	624,363	624,363	0.00%	$4,969,929.00
HOWLAND CAPITAL MANAGEMENT LLC	31 Dec, 2025	547,115	216,442	65.45%	$4,355,036.00
Sumitomo Mitsui Trust Group, Inc.	31 Dec, 2025	518,441	-72,555	-12.28%	$4,126,790.00
Amova Asset Management Americas, Inc.	31 Dec, 2025	518,441	-72,555	-12.28%	$4,126,790.00
STATE OF MICHIGAN RETIREMENT SYSTEM	31 Dec, 2025	493,798	0	0.00%	$3,930,632.00
Portolan Capital Management, LLC	31 Dec, 2025	379,197	379,197	0.00%	$3,018,408.00

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