Vaxcyte, Inc. (PCVX) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

135,785,331Shares Outstanding

3,757,564Shares held by institutions

$200,390,888Value of institutional holdings

103.56%Institutional ownership %

4.13%Shares Changed QoQ

279No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

According to SEC filings for the period ending December 2025, Vaxcyte, Inc. (NASDAQ:PCVX) is held by 279 institutional firms.

The percentage of Vaxcyte owned by institutions changed from 104.1% in September 2025 to 103.6% in December 2025, marking a slight down trend.
Quarterly data indicates a 4.13% shift in institutional share volume, and the annual owner count reflects a decrease of 12.26%.
The latest 13F cycle for Vaxcyte reveals that of 279 total investors, 147 funds grew their exposure, whereas 99 reduced theirs and 33 made no changes.
The total number of shares held by institutions in Vaxcyte increased to 140.61Mn as of December 2025, a net change of up by 5.57Mn shares quarter on quarter, and down 481.48K shares year over year.
FMR LLC continues to be the largest institutional holder of Vaxcyte as of December 31, 2025, with a position of 13.83Mn shares, representing 10.19% of the company's outstanding stock.
Among the most significant buyers of Vaxcyte during December 2025 were Caligan Partners LP (1.70Mn), ADAGE CAPITAL PARTNERS GP, L.L.C. (1.39Mn), FMR LLC (1.32Mn), Polar Capital Holdings Plc (1.26Mn), NORGES BANK (1.23Mn).
Leading sellers of Vaxcyte stock in December 2025 included T. Rowe Price Investment Management, Inc. (1.63Mn), RA CAPITAL MANAGEMENT, L.P. (1.24Mn), ROYAL BANK OF CANADA (939.83K), D. E. Shaw & Co., Inc. (659.74K), COMERICA BANK (653.27K).
The top 10 institutional holders of Vaxcyte for the quarter ending December 2025 included FMR LLC (13.83Mn), JANUS HENDERSON GROUP PLC (13.39Mn), VANGUARD GROUP INC (12.19Mn), RA CAPITAL MANAGEMENT, L.P. (10.72Mn), BlackRock, Inc. (10.25Mn), T. Rowe Price Investment Management, Inc. (6.68Mn), WELLINGTON MANAGEMENT GROUP LLP (5.97Mn), STATE STREET CORP (4.98Mn), Paradigm Biocapital Advisors LP (4.07Mn), Deep Track Capital, LP (4.00Mn).

279 Institutional Holders

3,757,564 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
FMR LLC	31 Dec, 2025	13,834,514	1,324,581	10.59%	$638,324,485.00
JANUS HENDERSON GROUP PLC	31 Dec, 2025	13,387,188	282,985	2.16%	$617,730,753.00
VANGUARD GROUP INC	31 Dec, 2025	12,193,986	-126,467	-1.03%	$562,630,515.00
RA CAPITAL MANAGEMENT, L.P.	31 Dec, 2025	10,724,599	-1,241,392	-10.37%	$494,832,998.00
BlackRock, Inc.	31 Dec, 2025	10,246,378	290,400	2.92%	$472,767,877.00
T. Rowe Price Investment Management, Inc.	31 Dec, 2025	6,682,676	-1,632,619	-19.63%	$308,339.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	5,966,310	933,539	18.55%	$275,285,543.00
STATE STREET CORP	31 Dec, 2025	4,980,005	194,116	4.06%	$229,777,431.00
Paradigm Biocapital Advisors LP	31 Dec, 2025	4,068,020	283,265	7.48%	$187,698,443.00
Deep Track Capital, LP	31 Dec, 2025	4,000,000	1,000,000	33.33%	$184,560,000.00
D. E. Shaw & Co., Inc.	31 Dec, 2025	3,631,053	-659,737	-15.38%	$167,536,785.00
WESTFIELD CAPITAL MANAGEMENT CO LP	31 Dec, 2025	3,539,717	-192,998	-5.17%	$163,322,542.00
Kynam Capital Management, LP	31 Dec, 2025	2,922,335	-149,253	-4.86%	$134,836,537.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	2,866,305	-17,735	-0.61%	$132,271,037.00
ADAGE CAPITAL PARTNERS GP, L.L.C.	31 Dec, 2025	1,725,000	1,392,000	418.02%	$79,591,500.00
Caligan Partners LP	31 Dec, 2025	1,704,815	1,704,815	0.00%	$78,660,164.00
Polar Capital Holdings Plc	31 Dec, 2025	1,672,783	1,257,253	302.57%	$77,182,208.00
Pivotal bioVenture Partners Investment Advisor LLC	31 Dec, 2025	1,372,425	0	0.00%	$63,323,690.00
MAVERICK CAPITAL LTD	31 Dec, 2025	1,354,237	64,670	5.01%	$62,484,495.00
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	31 Dec, 2025	1,293,830	423	0.03%	$59,697,316.00

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