Pacific Biosciences Of California, Inc. (PACB) Institutional Ownership

Ownership Summary

Pacific Biosciences Of California, Inc. (NASDAQ:PACB) appears in 209 institutional 13F filings for the quarter ending December 2025.

• These investors held 66.7% of outstanding shares in December 2025, up from 62.7% in September 2025.
• Their total shares held in PACB increased 20.64% from the prior quarter, while the number of investors in Pacific Biosciences Of California decreased 6.28% year over year.
• Activity in PACB broke down as 110 buyers, 53 sellers, and 46 unchanged among 209 total holders.
• In total, institutional investors held 200.63Mn shares in Pacific Biosciences Of California as of December 2025, up by 34.32Mn shares quarter on quarter, and down 67.01Mn shares year over year.
• As of December 31, 2025, ARK Investment Management LLC held the largest stake in Pacific Biosciences Of California with 36.27Mn shares, accounting for 12.06% of total shares outstanding.
• Leading buyers of Pacific Biosciences Of California shares for the quarter ending December 2025 were VANGUARD CAPITAL MANAGEMENT LLC (12.78Mn), VANGUARD PORTFOLIO MANAGEMENT LLC (2.87Mn), Nuveen, LLC (2.1Mn), VANGUARD FIDUCIARY TRUST CO (1.99Mn), BlackRock, Inc. (1.92Mn).
• The largest sales of PACB for the quarter ending December 2025 came from Casdin Capital, LLC (3.5Mn), Point72 Asset Management, L.P. (2.67Mn), Goldman Sachs Group Inc (1.77Mn), CITADEL ADVISORS LLC (1.59Mn), UBS Group AG (1.53Mn).
• Business Quant data shows the 10 biggest positions in Pacific Biosciences Of California as of December 2025 are held by ARK Investment Management LLC (36.27Mn), BlackRock, Inc. (25.27Mn), SOFTBANK GROUP CORP. (20.45Mn), VANGUARD CAPITAL MANAGEMENT LLC (12.78Mn), Amova Asset Management Americas, Inc. (7.04Mn), Sumitomo Mitsui Trust Group, Inc. (7.04Mn), GEODE CAPITAL MANAGEMENT, LLC (6.98Mn), State Street Corp (6.12Mn), MILLENNIUM MANAGEMENT LLC (4.89Mn), D. E. Shaw & Co., Inc. (3.64Mn).