Nautilus Biotechnology, Inc. (NAUT) Institutional Ownership

Ownership Summary

Nautilus Biotechnology, Inc. (NASDAQ:NAUT) appears in 68 institutional 13F filings for the quarter ending December 2025.

• These investors held 46.2% of outstanding shares in December 2025, up from 45.8% in September 2025.
• They increased total shares held in NAUT by 1.98% quarter over quarter, and investors in Nautilus Biotechnology decreased 24.44% from a year ago.
• Of these 68 funds, 30 grew their exposure to Nautilus Biotechnology, 14 cut back, and 24 maintained positions.
• The aggregate institutional position in Nautilus Biotechnology amounted to 58.41Mn shares as of December 2025, up by 1.13Mn shares quarter on quarter, and down 5.96Mn shares year over year.
• As of December 31, 2025, the biggest holder of Nautilus Biotechnology is a16z Capital Management, L.L.C. at 17.65Mn shares, representing 13.98% of shares outstanding.
• Top purchasers of NAUT stock for the quarter ending December 2025 included VANGUARD CAPITAL MANAGEMENT LLC (2.55Mn), Clearstead Advisors, LLC (2.33Mn), VANGUARD FIDUCIARY TRUST CO (305.53K), MILLENNIUM MANAGEMENT LLC (253.39K), MARSHALL WACE, LLP (202.82K).
• The largest sellers of Nautilus Biotechnology for the quarter ending December 2025 were Goldman Sachs Group Inc (204.11K), JANE STREET GROUP, LLC (145.04K), Corient Private Wealth LLC (114.79K), OMERS ADMINISTRATION Corp (80.28K), GSA CAPITAL PARTNERS LLP (69.35K).
• Per Business Quant, the top 10 investors in NAUT for the quarter ending December 2025 include a16z Capital Management, L.L.C. (17.65Mn), PERCEPTIVE ADVISORS LLC (12.59Mn), Cercano Management LLC (7.17Mn), VANGUARD CAPITAL MANAGEMENT LLC (2.55Mn), Clearstead Advisors, LLC (2.33Mn), Comprehensive Financial Management LLC (2.21Mn), Amazon Com Inc (1.46Mn), MILLENNIUM MANAGEMENT LLC (1.27Mn), SENTINEL TRUST CO LBA (750.0K), ACADIAN ASSET MANAGEMENT LLC (741.25K).