MeiraGTx Holdings plc (MGTX) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

81,472,581Shares Outstanding

21,585,387Shares held by institutions

$163,617,233Value of institutional holdings

79.74%Institutional ownership %

2.18%Shares Changed QoQ

122No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

According to SEC filings for the period ending December 2025, MeiraGTx Holdings plc (NASDAQ:MGTX) is held by 122 institutional firms.

The collective stake of institutional investors in MeiraGTx Holdings moved to 79.7% in December 2025, a shift up from the 78.7% reported for September 2025.
Institutional share ownership changed by 2.18% QoQ, while the number of institutional owners saw an increase of 20.79% YoY.
A review of institutional activity for MeiraGTx Holdings shows 61 of 122 filers increasing their positions, while 33 reduced their stake, and 28 remained unchanged.
The total number of shares held by institutions in MeiraGTx Holdings increased to 64.97Mn as of December 2025, a net change of up by 1.39Mn shares quarter on quarter, and up 6.75Mn shares year over year.
As of December 31, 2025, Sanofi held MeiraGTx Holdings's largest shareholding position with over 12.20Mn shares, representing 14.97% of total outstanding shares.
Among the most significant buyers of MeiraGTx Holdings during December 2025 were Rubric Capital Management LP (2.45Mn), MILLENNIUM MANAGEMENT LLC (604.12K), MORGAN STANLEY (587.26K), Opaleye Management Inc. (390.84K), Jefferies Financial Group Inc. (298.24K).
Leading sellers of MeiraGTx Holdings stock in December 2025 included PERCEPTIVE ADVISORS LLC (2.30Mn), J. Goldman & Co LP (1.48Mn), Prosight Management, LP (879.72K), ROYAL BANK OF CANADA (289.46K), ADAGE CAPITAL PARTNERS GP, L.L.C. (184.58K).
The top 10 institutional holders of MeiraGTx Holdings for the quarter ending December 2025 included Sanofi (12.20Mn), PERCEPTIVE ADVISORS LLC (10.33Mn), JOHNSON & JOHNSON (6.64Mn), Rubric Capital Management LP (6.18Mn), ADAGE CAPITAL PARTNERS GP, L.L.C. (4.00Mn), Prosight Management, LP (3.21Mn), MILLENNIUM MANAGEMENT LLC (3.18Mn), BlackRock, Inc. (3.07Mn), 683 Capital Management, LLC (2.56Mn), MORGAN STANLEY (1.83Mn).

122 Institutional Holders

21,585,387 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
Sanofi	31 Dec, 2025	12,197,737	0	0.00%	$96,972,009.00
PERCEPTIVE ADVISORS LLC	31 Dec, 2025	10,326,103	-2,300,000	-18.22%	$82,092,519.00
JOHNSON & JOHNSON	31 Dec, 2025	6,641,064	0	0.00%	$52,796,459.00
Rubric Capital Management LP	31 Dec, 2025	6,175,331	2,448,880	65.72%	$49,093,881.00
ADAGE CAPITAL PARTNERS GP, L.L.C.	31 Dec, 2025	4,000,000	-184,578	-4.41%	$31,800,000.00
Prosight Management, LP	31 Dec, 2025	3,209,788	-879,721	-21.51%	$25,517,815.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	3,176,390	604,121	23.49%	$25,252,300.00
BlackRock, Inc.	31 Dec, 2025	3,069,844	295,572	10.65%	$24,405,260.00
683 Capital Management, LLC	31 Dec, 2025	2,559,082	-65,918	-2.51%	$20,344,701.00
MORGAN STANLEY	31 Dec, 2025	1,829,252	587,258	47.28%	$14,542,554.00
Knoll Capital Management, LLC	31 Dec, 2025	1,250,000	0	0.00%	$9,937,500.00
Erste Asset Management GmbH	31 Dec, 2025	789,702	80,000	11.27%	$6,275,375.00
STATE STREET CORP	31 Dec, 2025	729,445	48,414	7.11%	$5,799,088.00
22NW, LP	31 Dec, 2025	586,519	0	0.00%	$4,662,826.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	573,783	18,470	3.33%	$4,561,574.00
Long Focus Capital Management, LLC	31 Dec, 2025	524,745	0	0.00%	$4,171,723.00
VANGUARD GROUP INC	31 Dec, 2025	494,753	30,818	6.64%	$3,933,287.00
GOLDMAN SACHS GROUP INC	31 Dec, 2025	456,744	196,525	75.52%	$3,631,115.00
Opaleye Management Inc.	31 Dec, 2025	390,844	390,844	0.00%	$3,107,210.00
D. E. Shaw & Co., Inc.	31 Dec, 2025	381,763	208,561	120.41%	$3,035,016.00

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