| FMR LLC |
31 Mar, 2026 |
7,085,423 |
190,935 |
2.77% |
$99,550,194.00 |
| Janus Henderson Group Plc |
31 Mar, 2026 |
6,211,338 |
6,211,338 |
0.00% |
$87,114,016.00 |
| Fairmount Funds Management LLC |
31 Mar, 2026 |
4,553,494 |
0 |
0.00% |
$63,976,591.00 |
| RA CAPITAL MANAGEMENT, L.P. |
31 Mar, 2026 |
3,671,083 |
0 |
0.00% |
$51,578,716.00 |
| Bellevue Group AG |
31 Mar, 2026 |
3,501,502 |
160,399 |
4.80% |
$49,196,103.00 |
| Venrock Adviser, LLC |
31 Mar, 2026 |
3,220,364 |
0 |
0.00% |
$45,246,114.00 |
| BlackRock, Inc. |
31 Mar, 2026 |
2,313,949 |
-556,364 |
-19.38% |
$32,510,984.00 |
| VANGUARD CAPITAL MANAGEMENT LLC |
31 Mar, 2026 |
1,796,652 |
1,796,652 |
0.00% |
$25,242,961.00 |
| BAKER BROS. ADVISORS LP |
31 Mar, 2026 |
1,641,137 |
0 |
0.00% |
$23,057,975.00 |
| Remedium Capital Partners, LLC |
31 Mar, 2026 |
1,577,750 |
0 |
0.00% |
$22,167,388.00 |
| Versant Venture Management, LLC |
31 Mar, 2026 |
1,525,820 |
0 |
0.00% |
$21,437,771.00 |
| Avidity Partners Management LP |
31 Mar, 2026 |
1,400,708 |
0 |
0.00% |
$34,177,275.00 |
| Samsara BioCapital, LLC |
31 Mar, 2026 |
968,798 |
0 |
0.00% |
$13,611,612.00 |
| GREAT POINT PARTNERS LLC |
31 Mar, 2026 |
964,462 |
158,189 |
19.62% |
$13,550,691.00 |
| MARSHALL WACE, LLP |
31 Mar, 2026 |
944,776 |
69,503 |
7.94% |
$13,274,106.00 |
| Aberdeen Group plc |
31 Mar, 2026 |
867,284 |
0 |
0.00% |
$12,185,340.00 |
| GEODE CAPITAL MANAGEMENT, LLC |
31 Mar, 2026 |
822,520 |
-19,288 |
-2.29% |
$11,559,273.00 |
| Soleus Capital Management, L.P. |
31 Mar, 2026 |
796,744 |
0 |
0.00% |
$11,194,253.00 |
| ACORN CAPITAL ADVISORS, LLC |
31 Mar, 2026 |
786,760 |
786,760 |
0.00% |
$11,053,978.00 |
| State Street Corp |
31 Mar, 2026 |
655,690 |
12,769 |
1.99% |
$9,212,445.00 |