Opus Genetics, Inc. (IRD) Institutional Ownership

Ownership Summary

Opus Genetics, Inc. (NASDAQ:IRD) has 59 institutional investors that have filed 13F reports for the period ending December 2025.

• Collectively, these holders controlled 39.5% of Opus Genetics's outstanding shares in December 2025, up from 27.6% in September 2025.
• They increased total shares held in IRD by 43.31% quarter over quarter, and investors in Opus Genetics increased 34.09% from a year ago.
• Among the 59 funds, 37 bought more Opus Genetics shares, 7 sold down, and 15 held their ground.
• Altogether, these fund groups held 27.89Mn shares in IRD by December 2025, up by 8.43Mn shares quarter on quarter, and up 21.63Mn shares year over year.
• As of December 31, 2025, Nantahala Capital Management, LLC held the largest stake in Opus Genetics with 4.78Mn shares, accounting for 6.77% of total shares outstanding.
• Leading buyers of Opus Genetics shares for the quarter ending December 2025 were BALYASNY ASSET MANAGEMENT L.P. (2.72Mn), MILLENNIUM MANAGEMENT LLC (2.0Mn), Nantahala Capital Management, LLC (1.44Mn), VANGUARD GROUP INC (980.87K), Mink Brook Asset Management LLC (427.68K).
• The biggest sellers of Opus Genetics for the quarter ending December 2025 included Voss Capital, LP (661.64K), RENAISSANCE TECHNOLOGIES LLC (47.5K), SIMPLEX TRADING, LLC (23.78K), KESTRA PRIVATE WEALTH SERVICES, LLC (3.0K), Raymond James Financial Inc (2.0K).
• Opus Genetics's 10 largest shareholders as of December 2025 include Nantahala Capital Management, LLC (4.78Mn), PERCEPTIVE ADVISORS LLC (4.32Mn), BIOS Capital Management, LP (3.68Mn), BALYASNY ASSET MANAGEMENT L.P. (2.72Mn), VANGUARD GROUP INC (2.32Mn), MILLENNIUM MANAGEMENT LLC (2.0Mn), Mink Brook Asset Management LLC (1.67Mn), Opaleye Management Inc. (1.12Mn), ADAGE CAPITAL PARTNERS GP, L.L.C. (1.1Mn), Bleichroeder LP (736.84K) per Business Quant data.