Gyre Therapeutics, Inc. (GYRE) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

120,333,333Shares Outstanding

54,530Shares held by institutions

$447,691Value of institutional holdings

2.79%Institutional ownership %

10.18%Shares Changed QoQ

45No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Gyre Therapeutics, Inc. (NASDAQ:GYRE) currently has 45 active institutional owners and shareholders as of today (December 2025), that have filed 13F forms with the Securities Exchange Commission (SEC).

These investors collectively held 2.8% of the company's total shares outstanding in December 2025, up from 2.6% in September 2025.
Institutional share ownership changed by 10.18% QoQ, while the number of institutional owners saw an increase of 7.14% YoY.
A review of institutional activity for Gyre Therapeutics shows 25 of 45 filers increasing their positions, while 9 reduced their stake, and 11 remained unchanged.
The total number of shares held by institutions in Gyre Therapeutics increased to 3.35Mn as of December 2025, a net change of up by 309.91K shares quarter on quarter, and up 1.74Mn shares year over year.
VANGUARD GROUP INC continues to be the largest institutional holder of Gyre Therapeutics as of December 31, 2025, with a position of 1.20Mn shares, representing 1.00% of the company's outstanding stock.
Among the most significant buyers of Gyre Therapeutics during December 2025 were BlackRock, Inc. (60.89K), VANGUARD GROUP INC (51.03K), GEODE CAPITAL MANAGEMENT, LLC (48.60K), CHARLES SCHWAB INVESTMENT MANAGEMENT INC (45.77K), MORGAN STANLEY (45.52K).
Leading sellers of Gyre Therapeutics stock in December 2025 included STATE OF WISCONSIN INVESTMENT BOARD (14.20K), UBS Group AG (13.38K), SBI Securities Co., Ltd. (4.95K), JANE STREET GROUP, LLC (2.96K), Tower Research Capital LLC (TRC) (617).
The top 10 institutional holders of Gyre Therapeutics for the quarter ending December 2025 included VANGUARD GROUP INC (1.20Mn), BlackRock, Inc. (720.29K), GEODE CAPITAL MANAGEMENT, LLC (423.22K), STATE STREET CORP (202.22K), CHARLES SCHWAB INVESTMENT MANAGEMENT INC (169.16K), SBI Securities Co., Ltd. (162.91K), NORTHERN TRUST CORP (128.85K), MORGAN STANLEY (54.50K), Bank of New York Mellon Corp (41.20K), GOLDMAN SACHS GROUP INC (31.11K).

45 Institutional Holders

54,530 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
VANGUARD GROUP INC	31 Dec, 2025	1,201,589	51,030	4.44%	$8,483,219.00
BlackRock, Inc.	31 Dec, 2025	720,291	60,894	9.23%	$5,085,254.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	423,222	48,602	12.97%	$2,988,936.00
STATE STREET CORP	31 Dec, 2025	202,225	19,472	10.65%	$1,427,709.00
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	31 Dec, 2025	169,158	45,772	37.10%	$1,194,255.00
SBI Securities Co., Ltd.	31 Dec, 2025	162,915	-4,951	-2.95%	$1,150,180.00
NORTHERN TRUST CORP	31 Dec, 2025	128,855	12,513	10.76%	$909,716.00
MORGAN STANLEY	31 Dec, 2025	54,498	45,517	506.81%	$384,757.00
Bank of New York Mellon Corp	31 Dec, 2025	41,203	16,805	68.88%	$290,894.00
GOLDMAN SACHS GROUP INC	31 Dec, 2025	31,108	13,074	72.50%	$219,622.00
STATE OF WISCONSIN INVESTMENT BOARD	31 Dec, 2025	24,800	-14,200	-36.41%	$175,088.00
ALLIANCEBERNSTEIN L.P.	31 Dec, 2025	21,830	0	0.00%	$154,120.00
STRS OHIO	31 Dec, 2025	21,100	0	0.00%	$148,966.00
BARCLAYS PLC	31 Dec, 2025	18,531	5,135	38.33%	$130,829.00
RHUMBLINE ADVISERS	31 Dec, 2025	14,032	600	4.47%	$99,057.00
WELLS FARGO & COMPANY/MN	31 Dec, 2025	12,919	7,361	132.44%	$91,208.00
ROYAL BANK OF CANADA	31 Dec, 2025	12,765	370	2.99%	$91,000.00
DIMENSIONAL FUND ADVISORS LP	31 Dec, 2025	10,903	10,903	0.00%	$76,975.00
DEUTSCHE BANK AG\	31 Dec, 2025	10,613	-314	-2.87%	$74,928.00
FMR LLC	31 Dec, 2025	10,304	100	0.98%	$72,746.00

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