Gyre Therapeutics, Inc. (GYRE) Institutional Ownership

Institutions by Trading Activity

120,333,333Shares Outstanding

26,954Shares held by institutions

$212,398Value of institutional holdings

1.16%Institutional ownership %

2.40%Shares Changed QoQ

9No. of institutional investors

According to SEC filings for the period ending December 2025, Gyre Therapeutics, Inc. (NASDAQ:GYRE) is held by 9 institutional firms.

These investors collectively held 1.2% of the company's total shares outstanding in December 2025, down from 2.6% in September 2025.
On a quarter-over-quarter basis, institutional holdings shifted by 2.40%, with a year-over-year a decrease of 78.57% in the count of filers.
During the quarter, 2 institutions bought more Gyre Therapeutics shares, 3 sold shares, and 4 of the 9 total investors held their position steady.
Collectively, institutional investors increased their stake in Gyre Therapeutics to 1.40Mn shares as of December 2025, a change that is up by 32.82K shares quarter on quarter and up 143.70K shares year over year.
As of December 31, 2025, VANGUARD GROUP INC held Gyre Therapeutics's largest shareholding position with over 1.20Mn shares, representing 1.00% of total outstanding shares.
Among the most significant buyers of Gyre Therapeutics during December 2025 were VANGUARD GROUP INC (51.03K), AMALGAMATED BANK (130).
Leading sellers of Gyre Therapeutics stock in December 2025 included UBS Group AG (13.38K), SBI Securities Co., Ltd. (4.95K), CWM, LLC (7).
The top 9 institutional holders of Gyre Therapeutics for the quarter ending December 2025 included VANGUARD GROUP INC (1.20Mn), SBI Securities Co., Ltd. (162.91K), STRS OHIO (21.10K), UBS Group AG (9.58K), State of Alaska, Department of Revenue (5.22K), Activest Wealth Management (533), AMALGAMATED BANK (371), NISA INVESTMENT ADVISORS, LLC (102), CWM, LLC (36).

26,954 Total Shares Held

Rows:

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
VANGUARD GROUP INC	30 Sep, 2025	1,150,559	850	0.07%	$8,583,170.00
BlackRock, Inc.	30 Sep, 2025	659,397	-183,212	-21.74%	$4,919,101.00
GEODE CAPITAL MANAGEMENT, LLC	30 Sep, 2025	374,620	-27,089	-6.74%	$2,795,243.00
STATE STREET CORP	30 Sep, 2025	182,753	4,985	2.80%	$1,363,337.00
SBI Securities Co., Ltd.	30 Sep, 2025	167,866	-64,433	-27.74%	$1,252,280.00
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	30 Sep, 2025	123,386	-6,034	-4.66%	$920,460.00
NORTHERN TRUST CORP	30 Sep, 2025	116,342	-26,987	-18.83%	$867,911.00
STATE OF WISCONSIN INVESTMENT BOARD	30 Sep, 2025	39,000	1,330	3.53%	$290,940.00
MILLENNIUM MANAGEMENT LLC	30 Sep, 2025	35,751	35,751	0.00%	$266,702.00
Bank of New York Mellon Corp	30 Sep, 2025	24,398	409	1.70%	$182,009.00
UBS Group AG	30 Sep, 2025	22,962	14,323	165.79%	$171,296.00
ALLIANCEBERNSTEIN L.P.	30 Sep, 2025	21,830	1,900	9.53%	$162,852.00
STRS OHIO	30 Sep, 2025	21,100	7,800	58.65%	$157,406.00
GOLDMAN SACHS GROUP INC	30 Sep, 2025	18,034	18,034	0.00%	$134,534.00
LAZARD ASSET MANAGEMENT LLC	30 Sep, 2025	14,932	14,932	0.00%	$111,393.00
RHUMBLINE ADVISERS	30 Sep, 2025	13,432	-2,754	-17.01%	$100,196.00
BARCLAYS PLC	30 Sep, 2025	13,396	-10,608	-44.19%	$99,934.00
JANE STREET GROUP, LLC	30 Sep, 2025	12,958	12,958	0.00%	$96,666.00
ROYAL BANK OF CANADA	30 Sep, 2025	12,395	6,133	97.94%	$92,000.00
DEUTSCHE BANK AG\	30 Sep, 2025	10,927	0	0.00%	$81,515.00

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