Structure Therapeutics GPCR Institutional Ownership

NASDAQ GPCR

$47.34 +0.00 (+0.00%)

As of: Sep 4, 2026 · 3:59 PM EDT

Institutions by Trading Activity

192 Institutions

Increased 106 55.2%

Unchanged 36 18.8%

Reduced 50 26.0%

Ownership Statistics

13F · as of 30 Jun, 2026

Institutional Ownership

30.98%

▲+0.22 pp QoQ

Shares Held by Institutions

67.53Mn

of 217.96Mn outstanding

▲+13.99% QoQ

Shares Outstanding

217.96Mn

150.43Mn held outside 13F filers

Institutional Investors

192

filed 13F for Jun 2026

▼-2 vs prior quarter

Net Shares Added (QoQ)

+8.29Mn

accumulated since last quarter

Value of Holdings

$3.20Bn

reported market value

Shares Owned by Institutions

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Institutions

Accumulated Distributed

Latest quarter —

Net over range —

Accumulating quarters —

Ownership Summary

Quarter ending 30 Jun, 2026

Structure Therapeutics Inc. (NASDAQ:GPCR) appears in 192 institutional 13F filings for the quarter ending June 2026.

Their combined ownership stood at 31.0% of outstanding shares in June 2026, up from 30.8% in March 2026.
They increased total shares held in GPCR by 13.99% quarter over quarter, and investors in Structure Therapeutics increased 12.94% from a year ago.
During the quarter, 106 of these 192 funds increased positions in GPCR, 50 reduced exposure, and 36 held steady.
Combined, these investors held 67.53Mn shares in GPCR for June 2026, up by 8.29Mn shares quarter on quarter, and up 15.0Mn shares year over year.
As of June 30, 2026, FMR LLC held the largest stake in Structure Therapeutics with 7.81Mn shares, accounting for 3.58% of total shares outstanding.
Top purchasers of GPCR stock for the quarter ending June 2026 included Jupiter Topco LLC (5.2Mn), RTW INVESTMENTS, LP (1.61Mn), ORBIMED ADVISORS LLC (734.0K), Morgan Stanley (501.18K), Deep Track Capital, LP (460.22K).
The biggest sellers of Structure Therapeutics for the quarter ending June 2026 included PRICE T ROWE ASSOCIATES INC /MD/ (1.16Mn), FMR LLC (593.14K), Siren, L.L.C. (455.73K), Jpmorgan Chase & Co (208.82K), STEMPOINT CAPITAL LP (162.09K).
Per Business Quant, the top 10 investors in GPCR for the quarter ending June 2026 include FMR LLC (7.81Mn), WELLINGTON MANAGEMENT GROUP LLP (7.38Mn), Avoro Capital Advisors LLC (6.56Mn), Jupiter Topco LLC (5.2Mn), Deep Track Capital, LP (4.74Mn), BVF INC/IL (3.37Mn), Morgan Stanley (2.81Mn), ORBIMED ADVISORS LLC (2.21Mn), Principal Financial Group Inc (1.75Mn), AMERICAN CENTURY COMPANIES INC (1.68Mn).

Form 13F Holdings

192 Institutional Holders

Report period 30 Jun, 2026

Total shares held 67.53Mn

Of outstanding 30.98%

#	Institution	CIK	Shares Held	% of Outstanding	Change (QoQ)	Change (%)	Value (USD)
1	FMR LLC	0000315066	7,810,306	3.58%	▼593,143	-7.06%	$419.18Mn
2	WELLINGTON MANAGEMENT GROUP LLP	0000902219	7,379,433	3.39%	▲119,146	+1.64%	$396.05Mn
3	Avoro Capital Advisors LLC	0001633313	6,555,555	3.01%	0	0.00%	$351.84Mn
4	Jupiter Topco LLC	0002146052	5,204,212	2.39%	▲5,204,212	0.00%	$279.34Mn
5	Deep Track Capital, LP	0001856083	4,740,072	2.17%	▲460,224	+10.75%	$254.40Mn
6	BVF INC/IL	0001056807	3,366,823	1.54%	▼92,535	-2.67%	$180.70Mn
7	Morgan Stanley	0000895421	2,806,640	1.29%	▲501,183	+21.74%	$150.63Mn
8	ORBIMED ADVISORS LLC	0001055951	2,209,400	1.01%	▲733,997	+49.75%	$118.58Mn
9	Principal Financial Group Inc	0001126328	1,752,753	0.80%	▼1,011	-0.06%	$94.07Mn
10	AMERICAN CENTURY COMPANIES INC	0000748054	1,682,179	0.77%	▲244,148	+16.98%	$90.28Mn
11	RTW INVESTMENTS, LP	0001493215	1,607,507	0.74%	▲1,607,507	0.00%	$86.27Mn
12	DRIEHAUS CAPITAL MANAGEMENT LLC	0000938206	1,553,219	0.71%	▼24,137	-1.53%	$83.36Mn
13	BAKER BROS. ADVISORS LP	0001263508	1,432,529	0.66%	0	0.00%	$76.88Mn
14	Casdin Capital, LLC	0001534261	1,175,000	0.54%	0	0.00%	$63.06Mn
15	DEERFIELD MANAGEMENT COMPANY, L.P.	0001009258	1,086,000	0.50%	▲318,007	+41.41%	$58.29Mn
16	CAPITOLIS LIQUID GLOBAL MARKETS LLC	0002094379	1,041,100	0.48%	▼110,200	-9.57%	$55.88Mn
17	Siren, L.L.C.	0002005245	872,967	0.40%	▼455,731	-34.30%	$46.85Mn
18	PRICE T ROWE ASSOCIATES INC /MD/	0000080255	845,532	0.39%	▼1,155,164	-57.74%	$45.38K
19	PACIFIC HEIGHTS ASSET MANAGEMENT LLC	0001323414	800,000	0.37%	▲50,000	+6.67%	$42.94Mn
20	Rock Springs Capital Management LP	0001595725	640,317	0.29%	▲100	+0.02%	$34.37Mn

Showing 1 to 20 of 192 holders