Edgewise Therapeutics EWTX Institutional Ownership

NASDAQ EWTX

$40.60 +1.41 (+3.60%)

At close: Sep 30, 2026 · 4:00 PM EDT

Institutions by Trading Activity

227 Institutions

Increased 128 56.4%

Unchanged 28 12.3%

Reduced 71 31.3%

Ownership Statistics

13F · as of 30 Jun, 2026

Institutional Ownership

111.14%

▲+0.49 pp QoQ

Shares Held by Institutions

119.66Mn

of 107.67Mn outstanding

▲+9.98% QoQ

Shares Outstanding

107.67Mn

-11.99Mn held outside 13F filers

Institutional Investors

227

filed 13F for Jun 2026

▲+15 vs prior quarter

Net Shares Added (QoQ)

+10.86Mn

accumulated since last quarter

Value of Holdings

$4.86Bn

reported market value

Shares Owned by Institutions

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Institutions

Accumulated Distributed

Latest quarter —

Net over range —

Accumulating quarters —

Ownership Summary

Quarter ending 30 Jun, 2026

Edgewise Therapeutics, Inc. (NASDAQ:EWTX) is held by 227 institutional investors per 13F filings through June 2026.

They owned 111.1% of outstanding stock in June 2026, up from 110.6% the prior quarter.
They increased total shares held in Edgewise Therapeutics by 9.98% from last quarter, and the number of investors in EWTX increased 28.25% annually.
Among the 227 funds, 128 bought more Edgewise Therapeutics shares, 71 sold down, and 28 held their ground.
Altogether, these fund groups held 119.66Mn shares in EWTX by June 2026, up by 10.86Mn shares quarter on quarter, and up 1.98Mn shares year over year.
As of June 30, 2026, ORBIMED ADVISORS LLC held the largest stake in Edgewise Therapeutics with 15.52Mn shares, accounting for 14.41% of total shares outstanding.
Top purchasers of EWTX stock for the quarter ending June 2026 included Jupiter Topco LLC (6.08Mn), FMR LLC (4.47Mn), Paradigm Biocapital Advisors LP (2.85Mn), PRICE T ROWE ASSOCIATES INC /MD/ (747.09K), Sixth Street Partners Management Company, L.P. (620.53K).
The largest sellers of Edgewise Therapeutics for the quarter ending June 2026 were BAKER BROS. ADVISORS LP (2.87Mn), RA CAPITAL MANAGEMENT, L.P. (2.04Mn), Siren, L.L.C. (1.25Mn), UBS Group AG (1.14Mn), Soleus Capital Management, L.P. (999.03K).
According to Business Quant data, leading holders of EWTX for June 2026 are ORBIMED ADVISORS LLC (15.52Mn), Paradigm Biocapital Advisors LP (10.22Mn), RA CAPITAL MANAGEMENT, L.P. (8.39Mn), BlackRock, Inc. (6.61Mn), Jupiter Topco LLC (6.08Mn), FMR LLC (5.49Mn), Novo Holdings A/S (5.35Mn), DRIEHAUS CAPITAL MANAGEMENT LLC (4.73Mn), PERCEPTIVE ADVISORS LLC (4.37Mn), VANGUARD CAPITAL MANAGEMENT LLC (3.86Mn).

Form 13F Holdings

227 Institutional Holders

Report period 30 Jun, 2026

Total shares held 119.66Mn

Of outstanding 111.14%

#	Institution	CIK	Shares Held	% of Outstanding	Change (QoQ)	Change (%)	Value (USD)
1	ORBIMED ADVISORS LLC	0001055951	15,518,492	14.41%	0	0.00%	$630.52Mn
2	Paradigm Biocapital Advisors LP	0001855655	10,215,455	9.49%	▲2,850,417	+38.70%	$415.05Mn
3	RA CAPITAL MANAGEMENT, L.P.	0001346824	8,392,730	7.79%	▼2,035,707	-19.52%	$341.00Mn
4	BlackRock, Inc.	0002012383	6,606,336	6.14%	▲133,345	+2.06%	$268.42Mn
5	Jupiter Topco LLC	0002146052	6,075,331	5.64%	▲6,075,331	0.00%	$246.95Mn
6	FMR LLC	0000315066	5,489,135	5.10%	▲4,472,083	+439.71%	$223.02Mn
7	Novo Holdings A/S	0001388325	5,350,000	4.97%	0	0.00%	$217.37Mn
8	DRIEHAUS CAPITAL MANAGEMENT LLC	0000938206	4,728,623	4.39%	▲250,681	+5.60%	$192.12Mn
9	PERCEPTIVE ADVISORS LLC	0001224962	4,373,974	4.06%	▼50,000	-1.13%	$177.71Mn
10	VANGUARD CAPITAL MANAGEMENT LLC	0002100119	3,860,670	3.59%	▲72,509	+1.91%	$156.86Mn
11	BAKER BROS. ADVISORS LP	0001263508	3,701,719	3.44%	▼2,874,221	-43.71%	$150.40Mn
12	Siren, L.L.C.	0002005245	3,184,629	2.96%	▼1,245,634	-28.12%	$129.39Mn
13	Cormorant Asset Management, LP	0001583977	2,510,000	2.33%	▼750,000	-23.01%	$101.98Mn
14	GEODE CAPITAL MANAGEMENT, LLC	0001214717	2,174,051	2.02%	▲384,232	+21.47%	$88.35Mn
15	ALLIANCEBERNSTEIN L.P.	0001109448	2,119,024	1.97%	▲396,855	+23.04%	$66.75Mn
16	Integral Health Asset Management, LLC	0001773206	2,000,000	1.86%	▲400,000	+25.00%	$81.26Mn
17	BRAIDWELL LP	0001920938	1,996,965	1.85%	▼350,618	-14.94%	$81.14Mn
18	Morgan Stanley	0000895421	1,948,597	1.81%	▼297,431	-13.24%	$79.17Mn
19	State Street Corp	0000093751	1,827,927	1.70%	▲111,104	+6.47%	$74.27Mn
20	MPM BioImpact LLC	0001687078	1,620,780	1.51%	▼39,916	-2.40%	$65.85Mn

Showing 1 to 20 of 227 holders