| # | Insider | Position | Direct | Indirect | Total | Share of Insiders | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Charles Cherington | TenPercentOwner | 6,779,440 | 0 | 6,779,440 | 54.6% | 17 Feb, 2026 |
| 2 | George P Iii Denny | TenPercentOwner | 0 | 4,775,120 | 4,775,120 | 38.4% | 20 Aug, 2021 |
| 3 | John D Halpern | TenPercentOwner | 0 | 450,961 | 450,961 | 3.6% | 05 Dec, 2022 |
| 4 | Nicholas Jason Singer | Director | 0 | 388,036 | 388,036 | 3.1% | 06 Dec, 2022 |
| 5 | Roger Sidhu | Chief Medical Officer | 20,163 | 0 | 20,163 | 0.2% | 21 Sep, 2022 |
| 6 | Kevin Damour | Chief Scientific Officer | 11,496 | 0 | 11,496 | 0.1% | 29 Jun, 2022 |
| 7 | Sandra M Gurrola | Sr. Vp Of Finance | 110 | 0 | 110 | 0.0% | 07 Jul, 2025 |
Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.
| Date | Insider | Position | Transaction | Shares | Price | Value | Shares Held After | Ownership |
|---|---|---|---|---|---|---|---|---|
| 31 Aug, 2026 | Peter Cicala | Director | Acquired A | 5,943 | $0.00 | $0 | 5,943 | Direct |
| 31 Aug, 2026 | James Arthur Bristol | Director | Acquired A | 8,320 | $0.00 | $0 | 8,320 | Direct |
| 31 Aug, 2026 | William A. Wexler | Director | Acquired A | 5,943 | $0.00 | $0 | 5,943 | Direct |
| 31 Aug, 2026 | Sanjeev Luther | President And Ceo | Acquired A | 118,848 | $0.00 | $0 | 118,848 | Direct |
| 31 Aug, 2026 | Elena Ratner | Director | Acquired A | 5,944 | $0.00 | $0 | 5,944 | Direct |
| 31 Aug, 2026 | David Polinsky | Director | Acquired A | 5,083 | $0.00 | $0 | 5,083 | Direct |
| 31 Aug, 2026 | Peter Cicala | Director | Acquired A | 5,083 | $0.00 | $0 | 5,083 | Direct |
| 31 Aug, 2026 | James Arthur Bristol | Director | Acquired A | 5,083 | $0.00 | $0 | 5,083 | Direct |
| 10 Feb, 2026 | Charles Cherington | TenPercentOwner | Acquired P | 4,000,000 | $0.50 | $2.00Mn | 6,779,440 | Direct |
| 10 Feb, 2026 | Charles Cherington | TenPercentOwner | Acquired P | 4,000,000 | — | — | 4,000,000 | Direct |
| 21 Jun, 2025 | Sandra M Gurrola | Sr. Vp Of Finance | Acquired M | 30 | — | — | 110 | Direct |
| 21 Jun, 2025 | Sandra M Gurrola | Sr. Vp Of Finance | Acquired M | 30 | $0.00 | $0 | 0 | Direct |
| 09 Jun, 2025 | Charles Cherington | TenPercentOwner | Acquired P | 21,241,163 | $0.10 | $2.22Mn | 41,659,743 | Direct |
| 02 Apr, 2025 | Charles Cherington | TenPercentOwner | Acquired P | 3,768,397 | $0.10 | $394.17K | 20,401,602 | Direct |
| 07 Feb, 2025 | William A. Wexler | Director | Acquired A | 124,533 | $0.00 | $0 | 124,533 | Direct |
| 07 Feb, 2025 | William A. Wexler | Director | Acquired A | 124,533 | $0.00 | $0 | 124,533 | Direct |
| 07 Feb, 2025 | William A. Wexler | Director | Acquired A | 124,533 | $0.00 | $0 | 124,533 | Direct |
| 07 Feb, 2025 | William A. Wexler | Director | Acquired A | 124,533 | $0.00 | $0 | 124,533 | Direct |
| 07 Feb, 2025 | Sandra M Gurrola | Sr. Vp Of Finance | Acquired A | 150,000 | $0.00 | $0 | 150,000 | Direct |
| 07 Feb, 2025 | Sanjeev Luther | President Ceo | Acquired A | 1,123,350 | $0.00 | $0 | 1,123,350 | Direct |