enGene Therapeutics Inc. (ENGN) Institutional Ownership

Institutions by Trading Activity

51,383,062Shares Outstanding

62,512,055Shares held by institutions

$437,584,385Value of institutional holdings

121.66%Institutional ownership %

66.57%Shares Changed QoQ

57No. of institutional investors

enGene Therapeutics Inc. (NASDAQ:ENGN) showed up in the 13F filings of 57 institutional investors as of December 2025.

They owned 121.4% of outstanding stock in December 2025, up from 81.3% the prior quarter.
Their total shares held in ENGN increased 66.18% quarter over quarter, and separately, investors owning enGene Therapeutics increased 62.86% from a year ago.
Among the 57 funds, 43 bought more enGene Therapeutics shares, 8 sold down, and 6 held their ground.
In total, institutional investors held 62.36Mn shares in enGene Therapeutics as of December 2025, up by 24.84Mn shares quarter on quarter, and up 20.61Mn shares year over year.
As of December 31, 2025, PFS Partners, LLC held the largest stake in enGene Therapeutics with 11.0K shares, accounting for 0.02% of total shares outstanding.
Per Business Quant, the top 1 investors in ENGN for the quarter ending December 2025 include PFS Partners, LLC (11.0K).

62,512,055 Total Shares Held

Rows:

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
FCPM III SERVICES B.V.	31 Dec, 2025	9,632,561	0	0.00%	$86,982,026.00
Blue Owl Capital Holdings LP	31 Dec, 2025	6,721,874	3,443,768	105.05%	$60,698,522.00
PERCEPTIVE ADVISORS LLC	31 Dec, 2025	5,869,076	3,771,840	179.85%	$52,997,756.00
VR Adviser, LLC	31 Dec, 2025	4,771,414	-275,000	-5.45%	$43,085,868.00
Deep Track Capital, LP	31 Dec, 2025	4,377,572	2,138,219	95.48%	$39,529,475.00
Cormorant Asset Management, LP	31 Dec, 2025	4,000,000	1,676,405	72.15%	$36,120,000.00
Siren, L.L.C.	31 Dec, 2025	3,336,264	3,336,264	0.00%	$30,126,464.00
BRAIDWELL LP	31 Dec, 2025	3,131,319	865,000	38.17%	$28,275,811.00
Nextech Invest, Ltd.	31 Dec, 2025	2,124,943	2,124,943	0.00%	$19,188,235.00
Janus Henderson Group Plc	31 Dec, 2025	1,900,000	1,900,000	0.00%	$17,109,500.00
MPM BioImpact LLC	31 Dec, 2025	1,840,898	1,310,599	247.14%	$16,623,309.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	1,499,520	1,479,018	7,214.02%	$13,540,666.00
Kynam Capital Management, LP	31 Dec, 2025	1,492,898	-3,501,192	-70.11%	$13,480,869.00
Franklin Resources Inc	31 Dec, 2025	1,388,000	350,000	33.72%	$12,533,640.00
Polar Capital Holdings Plc	31 Dec, 2025	1,142,982	1,142,982	0.00%	$10,321,127.00
Vestal Point Capital, LP	31 Dec, 2025	1,055,000	685,000	185.14%	$9,526,650.00
EVENTIDE ASSET MANAGEMENT, LLC	31 Dec, 2025	950,000	950,000	0.00%	$8,578,500.00
Omega Fund Management, LLC	31 Dec, 2025	876,357	350,000	66.49%	$7,913,504.00
SR ONE CAPITAL MANAGEMENT, LP	31 Dec, 2025	747,750	0	0.00%	$6,752,183.00
Morgan Stanley	31 Dec, 2025	718,485	283,194	65.06%	$6,487,919.00

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