enGene Holdings Inc. (ENGN) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

51,223,581Shares Outstanding

10,762,048Shares held by institutions

$106,436,655Value of institutional holdings

114.56%Institutional ownership %

56.40%Shares Changed QoQ

57No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Recent 13F filings as of December 2025 show that 57 institutional investors hold a position in enGene Holdings Inc. (NASDAQ:ENGN).

The percentage of enGene Holdings owned by institutions changed from 80.4% in September 2025 to 114.6% in December 2025, marking a slight up trend.
Institutional share ownership changed by 56.40% QoQ, while the number of institutional owners saw an increase of 58.33% YoY.
Of these 57 institutional investors, 42 increased their holdings in enGene Holdings, while 8 of them reduced positions, and 7 investors maintained their exposure.
Collectively, institutional investors increased their stake in enGene Holdings to 58.68Mn shares as of December 2025, a change that is up by 21.16Mn shares quarter on quarter and up 17.38Mn shares year over year.
FCPM III SERVICES B.V.'s holding of 9.63Mn shares as of December 31, 2025 makes it the primary institutional investor in enGene Holdings, owning 18.80% of the stock.
Among the most significant buyers of enGene Holdings during December 2025 were PERCEPTIVE ADVISORS LLC (3.77Mn), Siren, L.L.C. (3.34Mn), Deep Track Capital, LP (2.14Mn), Nextech Invest, Ltd. (2.12Mn), JANUS HENDERSON GROUP PLC (1.90Mn).
Leading sellers of enGene Holdings stock in December 2025 included Kynam Capital Management, LP (3.50Mn), Point72 Asset Management, L.P. (646.60K), VR Adviser, LLC (275.00K), CITADEL ADVISORS LLC (32.99K), Schonfeld Strategic Advisors LLC (8.43K).
The top 10 institutional holders of enGene Holdings for the quarter ending December 2025 included FCPM III SERVICES B.V. (9.63Mn), PERCEPTIVE ADVISORS LLC (5.87Mn), VR Adviser, LLC (4.77Mn), Deep Track Capital, LP (4.38Mn), Cormorant Asset Management, LP (4.00Mn), Blue Owl Capital Holdings LP (3.36Mn), Siren, L.L.C. (3.34Mn), BRAIDWELL LP (3.13Mn), Nextech Invest, Ltd. (2.12Mn), JANUS HENDERSON GROUP PLC (1.90Mn).

57 Institutional Holders

10,762,048 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
FCPM III SERVICES B.V.	31 Dec, 2025	9,632,561	0	0.00%	$86,982,026.00
PERCEPTIVE ADVISORS LLC	31 Dec, 2025	5,869,076	3,771,840	179.85%	$52,997,756.00
VR Adviser, LLC	31 Dec, 2025	4,771,414	-275,000	-5.45%	$43,085,868.00
Deep Track Capital, LP	31 Dec, 2025	4,377,572	2,138,219	95.48%	$39,529,475.00
Cormorant Asset Management, LP	31 Dec, 2025	4,000,000	1,676,405	72.15%	$36,120,000.00
Blue Owl Capital Holdings LP	31 Dec, 2025	3,360,937	82,831	2.53%	$30,349,261.00
Siren, L.L.C.	31 Dec, 2025	3,336,264	3,336,264	0.00%	$30,126,464.00
BRAIDWELL LP	31 Dec, 2025	3,131,319	865,000	38.17%	$28,275,811.00
Nextech Invest, Ltd.	31 Dec, 2025	2,124,943	2,124,943	0.00%	$19,188,235.00
JANUS HENDERSON GROUP PLC	31 Dec, 2025	1,900,000	1,900,000	0.00%	$17,109,500.00
MPM BioImpact LLC	31 Dec, 2025	1,840,898	1,310,599	247.14%	$16,623,309.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	1,499,520	1,479,018	7,214.02%	$13,540,666.00
Kynam Capital Management, LP	31 Dec, 2025	1,492,898	-3,501,192	-70.11%	$13,480,869.00
FRANKLIN RESOURCES INC	31 Dec, 2025	1,388,000	350,000	33.72%	$12,533,640.00
Polar Capital Holdings Plc	31 Dec, 2025	1,142,982	1,142,982	0.00%	$10,321,127.00
Vestal Point Capital, LP	31 Dec, 2025	1,055,000	685,000	185.14%	$9,526,650.00
EVENTIDE ASSET MANAGEMENT, LLC	31 Dec, 2025	950,000	950,000	0.00%	$8,578,500.00
Omega Fund Management, LLC	31 Dec, 2025	876,357	350,000	66.49%	$7,913,504.00
SR ONE CAPITAL MANAGEMENT, LP	31 Dec, 2025	747,750	0	0.00%	$6,752,183.00
MORGAN STANLEY	31 Dec, 2025	718,485	283,194	65.06%	$6,487,919.00

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