Dyne Therapeutics, Inc. (DYN) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

0Shares Outstanding

30,205,859Shares held by institutions

$516,218,130Value of institutional holdings

112.20%Institutional ownership %

4.15%Shares Changed QoQ

193No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Dyne Therapeutics, Inc. (NASDAQ:DYN) showed up in the 13F filings of 226 institutional investors as of December 2025.

They owned 125.6% of outstanding stock in December 2025, up from 112.8% the prior quarter.
Their total shares held in DYN increased 19.76% from the prior quarter, while the number of investors in Dyne Therapeutics increased 14.72% year over year.
Activity in DYN broke down as 146 buyers, 61 sellers, and 19 unchanged among 226 total holders.
Institutional investors collectively held 178.1Mn shares in Dyne Therapeutics as of December 2025, up by 29.38Mn shares quarter on quarter, and up 63.19Mn shares year over year.
As of December 31, 2025, the biggest holder of Dyne Therapeutics is T. Rowe Price Investment Management, Inc. at 20.41Mn shares, representing 14.39% of shares outstanding.
The most significant purchases of DYN for the quarter ending December 2025 came from T. Rowe Price Investment Management, Inc. (17.6Mn), Orbis Allan Gray Ltd (4.8Mn), PERCEPTIVE ADVISORS LLC (2.94Mn), ADAGE CAPITAL PARTNERS GP, L.L.C. (1.62Mn), BlackRock, Inc. (1.56Mn).
The largest sellers of Dyne Therapeutics for the quarter ending December 2025 were Jpmorgan Chase & Co (3.18Mn), Vestal Point Capital, LP (2.66Mn), MARSHALL WACE, LLP (2.34Mn), CITADEL ADVISORS LLC (2.24Mn), Point72 Asset Management, L.P. (1.39Mn).
Per Business Quant data, the top 10 holders of Dyne Therapeutics for the quarter ending December 2025 are T. Rowe Price Investment Management, Inc. (20.41Mn), Janus Henderson Group Plc (13.89Mn), VANGUARD GROUP INC (11.22Mn), BlackRock, Inc. (11.19Mn), Atlas Venture Life Science Advisors, LLC (9.13Mn), State Street Corp (6.69Mn), FMR LLC (6.57Mn), FCPM III SERVICES B.V. (5.46Mn), ADAGE CAPITAL PARTNERS GP, L.L.C. (5.17Mn), Orbis Allan Gray Ltd (4.8Mn).

226 Institutional Holders

30,205,859 Total Shares Held

Rows:

Download Data

Owner Name	Date	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	1,555,929	16.15%	$0.00
Janus Henderson Group Plc	31 Dec, 2025	-857,783	-5.82%	$0.00
T. Rowe Price Investment Management, Inc.	31 Dec, 2025	17,598,235	625.73%	$0.00
Barclays Plc	31 Dec, 2025	-239,352	-34.79%	$0.00
VANGUARD GROUP INC	31 Dec, 2025	1,455,151	14.91%	$0.00
Atlas Venture Life Science Advisors, LLC	31 Dec, 2025	0	0.00%	$0.00
Rockefeller Capital Management L.P.	31 Dec, 2025	19,998	234.22%	$0.00
State Street Corp	31 Dec, 2025	1,423,828	27.02%	$0.00
FCPM III SERVICES B.V.	31 Dec, 2025	0	0.00%	$0.00
FMR LLC	31 Dec, 2025	1,168,005	21.62%	$0.00
Orbis Allan Gray Ltd	31 Dec, 2025	4,801,928	0.00%	$0.00
ADAGE CAPITAL PARTNERS GP, L.L.C.	31 Dec, 2025	1,618,000	45.53%	$0.00
TCG Crossover Management, LLC	31 Dec, 2025	0	0.00%	$0.00
Jpmorgan Chase & Co	31 Dec, 2025	-3,180,581	-47.26%	$0.00
Siren, L.L.C.	31 Dec, 2025	-1,226,233	-25.93%	$0.00
PERCEPTIVE ADVISORS LLC	31 Dec, 2025	2,938,500	543.72%	$0.00
Frazier Life Sciences Management, L.P.	31 Dec, 2025	434,977	16.00%	$0.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	395,824	13.80%	$0.00
Deep Track Capital, LP	31 Dec, 2025	650,000	32.50%	$0.00
ARMISTICE CAPITAL, LLC	31 Dec, 2025	185,708	6.06%	$0.00

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