Caribou Biosciences, Inc. (CRBU) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

0Shares Outstanding

6,407,970Shares held by institutions

$10,989,669Value of institutional holdings

43.99%Institutional ownership %

-19.76%Shares Changed QoQ

127No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Caribou Biosciences, Inc. (NASDAQ:CRBU) is held by 120 institutional investors per 13F filings through December 2025.

Their combined ownership stood at 39.7% of outstanding shares in December 2025, down from 40.6% in September 2025.
Their total shares held in CRBU increased 2.66% from the prior quarter, while the number of investors in Caribou Biosciences decreased 6.98% year over year.
During the quarter, 51 of these 120 funds increased positions in CRBU, 35 reduced exposure, and 34 held steady.
Combined, these investors held 37.05Mn shares in CRBU for December 2025, up by 958.67K shares quarter on quarter, and down 21.97Mn shares year over year.
As of December 31, 2025, the biggest holder of Caribou Biosciences is Pfizer Inc at 4.69Mn shares, representing 5.03% of shares outstanding.
The most significant purchases of CRBU for the quarter ending December 2025 came from RENAISSANCE TECHNOLOGIES LLC (859.44K), MARSHALL WACE, LLP (755.26K), BlackRock, Inc. (681.7K), SUSQUEHANNA INTERNATIONAL GROUP, LLP (585.77K), JACOBS LEVY EQUITY MANAGEMENT, INC (475.22K).
The largest sales of CRBU for the quarter ending December 2025 came from MILLENNIUM MANAGEMENT LLC (2.45Mn), Bank Of America Corp /De/ (1.16Mn), Kynam Capital Management, LP (564.47K), Royal Bank Of Canada (559.39K), PFM Health Sciences, LP (401.04K).
Per Business Quant data, the top 10 holders of Caribou Biosciences for the quarter ending December 2025 are Pfizer Inc (4.69Mn), VANGUARD GROUP INC (4.3Mn), Kynam Capital Management, LP (2.5Mn), BlackRock, Inc. (2.14Mn), RENAISSANCE TECHNOLOGIES LLC (1.64Mn), Aberdeen Group plc (1.39Mn), TWO SIGMA ADVISERS, LP (1.12Mn), SUSQUEHANNA INTERNATIONAL GROUP, LLP (1.03Mn), TWO SIGMA INVESTMENTS, LP (1.02Mn), DIMENSIONAL FUND ADVISORS LP (1.01Mn).

120 Institutional Holders

6,407,970 Total Shares Held

Rows:

Download Data

Owner Name	Date	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	681,703	46.71%	$0.00
Pfizer Inc	31 Dec, 2025	0	0.00%	$0.00
Kynam Capital Management, LP	31 Dec, 2025	-564,472	-18.40%	$0.00
HSBC HOLDINGS PLC	31 Dec, 2025	34,460	100.00%	$0.00
VANGUARD GROUP INC	31 Dec, 2025	77,272	1.83%	$0.00
Aberdeen Group plc	31 Dec, 2025	0	0.00%	$0.00
Barclays Plc	31 Dec, 2025	-129,923	-85.69%	$0.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	859,436	110.12%	$0.00
UBS Group AG	31 Dec, 2025	318,453	99.74%	$0.00
TWO SIGMA ADVISERS, LP	31 Dec, 2025	-111,700	-9.10%	$0.00
72 Investment Holdings, LLC	31 Dec, 2025	0	0.00%	$0.00
SUSQUEHANNA INTERNATIONAL GROUP, LLP	31 Dec, 2025	585,768	131.45%	$0.00
XTX Topco Ltd	31 Dec, 2025	413,380	0.00%	$0.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	236,489	30.18%	$0.00
Point72 Asset Management, L.P.	31 Dec, 2025	115,391	39.99%	$0.00
DIMENSIONAL FUND ADVISORS LP	31 Dec, 2025	-204,300	-16.88%	$0.00
MILESTONE ASSET MANAGEMENT, LLC	31 Dec, 2025	55,832	31.73%	$0.00
Bank Of America Corp /De/	31 Dec, 2025	-1,155,698	-53.78%	$0.00
Qube Research & Technologies Ltd	31 Dec, 2025	159,502	353.27%	$0.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	-8,313	-0.84%	$0.00

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