Catalyst Pharmaceuticals, Inc. (CPRX) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

127,090,194Shares Outstanding

105,000,925Shares held by institutions

$3,271,303,818Value of institutional holdings

82.62%Institutional ownership %

3.04%Shares Changed QoQ

365No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Catalyst Pharmaceuticals, Inc. (NASDAQ:CPRX) showed up in the 13F filings of 365 institutional investors as of December 2025.

Their combined ownership stood at 81.8% of outstanding shares in December 2025, down from 83.5% in September 2025.
Their total shares held in CPRX increased 2.58% quarter over quarter, and separately, investors owning Catalyst Pharmaceuticals increased 9.28% from a year ago.
Of these 365 funds, 184 grew their exposure to Catalyst Pharmaceuticals, 128 cut back, and 53 maintained positions.
Combined, these investors held 103.9Mn shares in CPRX for December 2025, up by 2.62Mn shares quarter on quarter, and up 2.79Mn shares year over year.
As of December 31, 2025, the biggest holder of Catalyst Pharmaceuticals is Linden Thomas Advisory Services, LLC at 163.59K shares, representing 0.13% of shares outstanding.
The biggest buyers of Catalyst Pharmaceuticals for the quarter ending December 2025 included SG Americas Securities, LLC (128.78K), Linden Thomas Advisory Services, LLC (23.69K), WESBANCO BANK INC (23.0K), WEALTH ENHANCEMENT ADVISORY SERVICES, LLC (22.27K), Assenagon Asset Management S.A. (21.88K).
The largest sellers of Catalyst Pharmaceuticals for the quarter ending December 2025 were Janney Montgomery Scott LLC (45.38K), OPPENHEIMER & CO INC (38.86K), JUNCTURE WEALTH STRATEGIES, LLC (12.53K), EXCHANGE TRADED CONCEPTS, LLC (7.23K), State of Alaska, Department of Revenue (1.82K).
Business Quant data shows the 10 biggest positions in Catalyst Pharmaceuticals as of December 2025 are held by Linden Thomas Advisory Services, LLC (163.59K), SG Americas Securities, LLC (161.55K), Assenagon Asset Management S.A. (160.62K), Stanley-Laman Group, Ltd. (155.02K), Cyndeo Wealth Partners, LLC (118.44K), Oliver Luxxe Assets LLC (96.64K), CAMPBELL NEWMAN ASSET MANAGEMENT INC (92.48K), State of Alaska, Department of Revenue (86.18K), WESBANCO BANK INC (79.0K), JUNCTURE WEALTH STRATEGIES, LLC (71.81K).

365 Institutional Holders

105,000,925 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	18,626,781	410,721	2.25%	$434,749,068.00
VANGUARD GROUP INC	31 Dec, 2025	8,432,247	-281,273	-3.23%	$196,808,646.00
State Street Corp	31 Dec, 2025	6,907,622	502,235	7.84%	$161,223,897.00
DEERFIELD MANAGEMENT COMPANY, L.P.	31 Dec, 2025	4,911,161	-63,606	-1.28%	$114,626,498.00
Fundsmith LLP	31 Dec, 2025	3,363,807	0	0.00%	$78,511,255.00
AMERICAN CENTURY COMPANIES INC	31 Dec, 2025	3,025,271	497,085	19.66%	$70,609,825.00
DIMENSIONAL FUND ADVISORS LP	31 Dec, 2025	2,996,297	538,128	21.89%	$69,932,608.00
Morgan Stanley	31 Dec, 2025	2,933,399	1,089,775	59.11%	$68,465,565.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	2,900,337	10,017	0.35%	$67,704,365.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	2,650,077	-894,753	-25.24%	$61,852,797.00
Bank Of America Corp /De/	31 Dec, 2025	2,199,842	-2,382,986	-52.00%	$51,344,312.00
Goldman Sachs Group Inc	31 Dec, 2025	1,959,086	951,851	94.50%	$45,725,068.00
ROYCE & ASSOCIATES LP	31 Dec, 2025	1,910,767	-124,198	-6.10%	$44,597,302.00
Janus Henderson Group Plc	31 Dec, 2025	1,719,767	1,147,565	200.55%	$40,123,723.00
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	31 Dec, 2025	1,617,208	312,434	23.95%	$37,745,635.00
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	31 Dec, 2025	1,356,499	24,509	1.84%	$31,660,687.00
Invesco Ltd.	31 Dec, 2025	1,293,478	60,221	4.88%	$30,189,776.00
Swedbank AB	31 Dec, 2025	1,232,264	616,132	100.00%	$28,761,042.00
Boston Partners	31 Dec, 2025	1,231,372	-59,687	-4.62%	$28,539,969.00
Northern Trust Corp	31 Dec, 2025	1,211,973	-51,915	-4.11%	$28,287,449.00

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