Catalyst Pharmaceuticals, Inc. (CPRX) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

125,673,810Shares Outstanding

5,551,457Shares held by institutions

$136,787,900Value of institutional holdings

79.84%Institutional ownership %

4.85%Shares Changed QoQ

351No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Recent 13F filings as of December 2025 show that 351 institutional investors hold a position in Catalyst Pharmaceuticals, Inc. (NASDAQ:CPRX).

These investors collectively held 79.8% of the company's total shares outstanding in December 2025, down from 82.3% in September 2025.
On a quarter-over-quarter basis, institutional holdings shifted by 4.85%, with a year-over-year an increase of 5.41% in the count of filers.
A review of institutional activity for Catalyst Pharmaceuticals shows 179 of 351 filers increasing their positions, while 116 reduced their stake, and 56 remained unchanged.
This class of investors increased its holdings in Catalyst Pharmaceuticals to 100.34Mn shares for the 13F-cycle ending December 2025, up by 4.64Mn shares quarter on quarter, and up 2.87Mn shares year over year.
BlackRock, Inc.'s holding of 18.63Mn shares as of December 31, 2025 makes it the primary institutional investor in Catalyst Pharmaceuticals, owning 14.82% of the stock.
Among the most significant buyers of Catalyst Pharmaceuticals during December 2025 were JANUS HENDERSON GROUP PLC (1.15Mn), MORGAN STANLEY (1.09Mn), NOMURA ASSET MANAGEMENT INTERNATIONAL INC. (778.59K), GLENMEDE TRUST CO NA (618.22K), DIMENSIONAL FUND ADVISORS LP (538.13K).
Leading sellers of Catalyst Pharmaceuticals stock in December 2025 included RENAISSANCE TECHNOLOGIES LLC (894.75K), Allianz Asset Management GmbH (431.19K), MILLENNIUM MANAGEMENT LLC (372.04K), Qube Research & Technologies Ltd (334.07K), VANGUARD GROUP INC (281.27K).
The top 10 institutional holders of Catalyst Pharmaceuticals for the quarter ending December 2025 included BlackRock, Inc. (18.63Mn), VANGUARD GROUP INC (8.43Mn), STATE STREET CORP (6.91Mn), DEERFIELD MANAGEMENT COMPANY, L.P. (4.91Mn), Fundsmith LLP (3.36Mn), AMERICAN CENTURY COMPANIES INC (3.03Mn), DIMENSIONAL FUND ADVISORS LP (3.00Mn), MORGAN STANLEY (2.93Mn), GEODE CAPITAL MANAGEMENT, LLC (2.90Mn), RENAISSANCE TECHNOLOGIES LLC (2.65Mn).

351 Institutional Holders

5,551,457 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	18,626,781	410,721	2.25%	$434,749,068.00
VANGUARD GROUP INC	31 Dec, 2025	8,432,247	-281,273	-3.23%	$196,808,646.00
STATE STREET CORP	31 Dec, 2025	6,907,622	502,235	7.84%	$161,223,897.00
DEERFIELD MANAGEMENT COMPANY, L.P.	31 Dec, 2025	4,911,161	-63,606	-1.28%	$114,626,498.00
Fundsmith LLP	31 Dec, 2025	3,363,807	0	0.00%	$78,511,255.00
AMERICAN CENTURY COMPANIES INC	31 Dec, 2025	3,025,271	497,085	19.66%	$70,609,825.00
DIMENSIONAL FUND ADVISORS LP	31 Dec, 2025	2,996,297	538,128	21.89%	$69,932,608.00
MORGAN STANLEY	31 Dec, 2025	2,933,399	1,089,775	59.11%	$68,465,565.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	2,900,337	10,017	0.35%	$67,704,365.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	2,650,077	-894,753	-25.24%	$61,852,797.00
BANK OF AMERICA CORP /DE/	31 Dec, 2025	2,199,842	-91,572	-4.00%	$51,344,312.00
ROYCE & ASSOCIATES LP	31 Dec, 2025	1,910,767	-124,198	-6.10%	$44,597,302.00
JANUS HENDERSON GROUP PLC	31 Dec, 2025	1,719,767	1,147,565	200.55%	$40,123,723.00
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	31 Dec, 2025	1,617,208	312,434	23.95%	$37,745,635.00
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	31 Dec, 2025	1,356,499	24,509	1.84%	$31,660,687.00
Boston Partners	31 Dec, 2025	1,231,372	-59,687	-4.62%	$28,539,969.00
NORTHERN TRUST CORP	31 Dec, 2025	1,211,973	-51,915	-4.11%	$28,287,449.00
KENNEDY CAPITAL MANAGEMENT LLC	31 Dec, 2025	1,209,692	149,485	14.10%	$28,234,211.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	993,647	-372,035	-27.24%	$23,191,721.00
GOLDMAN SACHS GROUP INC	31 Dec, 2025	979,543	-27,692	-2.75%	$22,862,534.00

1 - 20 of 351

Research Tools