Catalyst Pharmaceuticals, Inc. (CPRX) Institutional Ownership

Institutions by Trading Activity

127,090,194Shares Outstanding

104,968,568Shares held by institutions

$2,717,636,226Value of institutional holdings

82.59%Institutional ownership %

3.00%Shares Changed QoQ

365No. of institutional investors

Catalyst Pharmaceuticals, Inc. (NASDAQ:CPRX) appears in 365 institutional 13F filings for the quarter ending December 2025.

Collectively, these holders controlled 81.8% of Catalyst Pharmaceuticals's outstanding shares in December 2025, down from 83.5% in September 2025.
Their total shares held in CPRX increased 2.58% quarter over quarter, and separately, investors owning Catalyst Pharmaceuticals increased 9.28% from a year ago.
Among the 365 funds, 184 bought more Catalyst Pharmaceuticals shares, 128 sold down, and 53 held their ground.
Institutional investors collectively held 103.9Mn shares in Catalyst Pharmaceuticals as of December 2025, up by 2.62Mn shares quarter on quarter, and up 2.79Mn shares year over year.
Hilltop National Bank leads ownership in CPRX with 900 shares as of December 31, 2025, equal to 0.0% of outstanding shares.
Business Quant data shows the 2 biggest positions in Catalyst Pharmaceuticals as of December 2025 are held by Hilltop National Bank (900), Bangor Savings Bank (100).

104,968,568 Total Shares Held

Rows:

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	18,626,781	410,721	2.25%	$434,749,068.00
VANGUARD GROUP INC	31 Dec, 2025	8,432,247	-281,273	-3.23%	$196,808,646.00
State Street Corp	31 Dec, 2025	6,907,622	502,235	7.84%	$161,223,897.00
DEERFIELD MANAGEMENT COMPANY, L.P.	31 Dec, 2025	4,911,161	-63,606	-1.28%	$114,626,498.00
Fundsmith LLP	31 Dec, 2025	3,363,807	0	0.00%	$78,511,255.00
AMERICAN CENTURY COMPANIES INC	31 Dec, 2025	3,025,271	497,085	19.66%	$70,609,825.00
DIMENSIONAL FUND ADVISORS LP	31 Dec, 2025	2,996,297	538,128	21.89%	$69,932,608.00
Morgan Stanley	31 Dec, 2025	2,933,399	1,089,775	59.11%	$68,465,565.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	2,900,337	10,017	0.35%	$67,704,365.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	2,650,077	-894,753	-25.24%	$61,852,797.00
Bank Of America Corp /De/	31 Dec, 2025	2,199,842	-2,382,986	-52.00%	$51,344,312.00
Goldman Sachs Group Inc	31 Dec, 2025	1,959,086	951,851	94.50%	$45,725,068.00
ROYCE & ASSOCIATES LP	31 Dec, 2025	1,910,767	-124,198	-6.10%	$44,597,302.00
Janus Henderson Group Plc	31 Dec, 2025	1,719,767	1,147,565	200.55%	$40,123,723.00
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	31 Dec, 2025	1,617,208	312,434	23.95%	$37,745,635.00
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	31 Dec, 2025	1,356,499	24,509	1.84%	$31,660,687.00
Invesco Ltd.	31 Dec, 2025	1,293,478	60,221	4.88%	$30,189,776.00
Swedbank AB	31 Dec, 2025	1,232,264	616,132	100.00%	$28,761,042.00
Boston Partners	31 Dec, 2025	1,231,372	-59,687	-4.62%	$28,539,969.00
Northern Trust Corp	31 Dec, 2025	1,211,973	-51,915	-4.11%	$28,287,449.00

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