Climb Bio, Inc. (CLYM) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

67,831,579Shares Outstanding

2,794,569Shares held by institutions

$15,677,532Value of institutional holdings

43.03%Institutional ownership %

-28.91%Shares Changed QoQ

61No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

According to SEC filings for the period ending December 2025, Climb Bio, Inc. (NASDAQ:CLYM) is held by 61 institutional firms.

Climb Bio saw its institutional ownership percentage fell to 43.0% in December 2025 from 65.7% in September 2025.
In percentage terms, this reflects as a holdings change of -28.91% quarter on quarter, and a decrease of 24.69% year over year.
A review of institutional activity for Climb Bio shows 34 of 61 filers increasing their positions, while 21 reduced their stake, and 6 remained unchanged.
Collectively, institutional investors decreased their stake in Climb Bio to 29.19Mn shares as of December 2025, a change that is down by 11.87Mn shares quarter on quarter and down 26.44Mn shares year over year.
The top institutional stake in Climb Bio as of December 31, 2025 belongs to RA CAPITAL MANAGEMENT, L.P., which owns 11.29Mn shares, or 16.65% of the company.
Among the most significant buyers of Climb Bio during December 2025 were MPM BioImpact LLC (2.67Mn), ADAR1 Capital Management, LLC (1.30Mn), GREAT POINT PARTNERS LLC (979.53K), Point72 Asset Management, L.P. (716.68K), DRIEHAUS CAPITAL MANAGEMENT LLC (600.95K).
Leading sellers of Climb Bio stock in December 2025 included RA CAPITAL MANAGEMENT, L.P. (20.13Mn), BlackRock, Inc. (346.19K), UBS Group AG (334.08K), CITIGROUP INC (319.22K), RENAISSANCE TECHNOLOGIES LLC (216.50K).
The top 10 institutional holders of Climb Bio for the quarter ending December 2025 included RA CAPITAL MANAGEMENT, L.P. (11.29Mn), MPM BioImpact LLC (2.67Mn), ADAR1 Capital Management, LLC (1.43Mn), VANGUARD GROUP INC (1.34Mn), Affinity Asset Advisors, LLC (1.30Mn), Kynam Capital Management, LP (1.03Mn), GREAT POINT PARTNERS LLC (979.53K), SPHERA FUNDS MANAGEMENT LTD. (932.25K), Point72 Asset Management, L.P. (716.68K), DRIEHAUS CAPITAL MANAGEMENT LLC (600.95K).

61 Institutional Holders

2,794,569 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
RA CAPITAL MANAGEMENT, L.P.	31 Dec, 2025	11,293,828	-20,125,439	-64.05%	$77,711,233.00
MPM BioImpact LLC	31 Dec, 2025	2,671,480	2,671,480	0.00%	$10,685,920.00
ADAR1 Capital Management, LLC	31 Dec, 2025	1,432,475	1,298,945	972.77%	$5,729,900.00
VANGUARD GROUP INC	31 Dec, 2025	1,340,504	24,693	1.88%	$5,362,016.00
Affinity Asset Advisors, LLC	31 Dec, 2025	1,300,000	0	0.00%	$5,200,000.00
Kynam Capital Management, LP	31 Dec, 2025	1,028,341	0	0.00%	$4,113,364.00
GREAT POINT PARTNERS LLC	31 Dec, 2025	979,534	979,534	0.00%	$3,918,136.00
SPHERA FUNDS MANAGEMENT LTD.	31 Dec, 2025	932,247	497,410	114.39%	$3,728,988.00
Point72 Asset Management, L.P.	31 Dec, 2025	716,680	716,680	0.00%	$2,866,720.00
DRIEHAUS CAPITAL MANAGEMENT LLC	31 Dec, 2025	600,946	600,946	0.00%	$2,403,784.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	566,712	454,031	402.93%	$2,266,848.00
Peapod Lane Capital LLC	31 Dec, 2025	565,992	4,126	0.73%	$2,263,968.00
NAN FUNG TRINITY (HK) Ltd	31 Dec, 2025	463,654	0	0.00%	$1,854,616.00
SUSQUEHANNA INTERNATIONAL GROUP, LLP	31 Dec, 2025	445,342	302,892	212.63%	$1,781,368.00
KOTLER KEVIN	31 Dec, 2025	400,000	400,000	0.00%	$1,600,000.00
BlackRock, Inc.	31 Dec, 2025	389,309	-346,194	-47.07%	$1,557,236.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	320,600	-216,500	-40.31%	$1,282,400.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	310,756	-965	-0.31%	$1,243,615.00
MARSHALL WACE, LLP	31 Dec, 2025	304,015	74,126	32.24%	$1,216,060.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	296,314	-175,390	-37.18%	$1,185,256.00

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