As of September 29, 2026, the three largest insider holders of CGTX are Memory Spv I, Lp Bios (TenPercentOwner, 3.91Mn shares), Aaron G.L. Fletcher (Director, 3.91Mn shares), Aaron G.L. Fletcher (Director, 2.66Mn shares).
| # | Insider | Position | Direct | Indirect | Total | Share of Insiders | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Memory Spv I, Lp Bios | TenPercentOwner | 1,424,014 | 2,488,827 | 3,912,841 | 38.3% | 15 Oct, 2021 |
| 2 | Cap Associates, Llc Ogden | TenPercentOwner | 2,210,377 | 0 | 2,210,377 | 21.6% | 15 Oct, 2021 |
| 3 | Lisa Ricciardi | Ceo President | 1,715,851 | 0 | 1,715,851 | 16.8% | 20 Apr, 2026 |
| 4 | Anthony Caggiano | Chief Medical Officer | 874,906 | 0 | 874,906 | 8.6% | 20 Apr, 2026 |
| 5 | John Brendan Doyle | Chief Financial Officer | 618,942 | 0 | 618,942 | 6.1% | 04 May, 2026 |
| 6 | Mark H. Breedlove | Director | 0 | 404,439 | 404,439 | 4.0% | 15 Oct, 2021 |
| 7 | Peggy Wallace | Director | 111,461 | 0 | 111,461 | 1.1% | 22 Jun, 2026 |
| 8 | Ellen B Richstone | Director | 83,500 | 0 | 83,500 | 0.8% | 22 Jun, 2026 |
| 9 | Aaron G.L. Fletcher | Director, TenPercentOwner | 81,229 | 0 | 81,229 | 0.8% | 22 Jun, 2026 |
| 10 | Jack A. Khattar | Director | 73,500 | 0 | 73,500 | 0.7% | 22 Jun, 2026 |
| 11 | Brett P Monia | Director | 73,500 | 0 | 73,500 | 0.7% | 22 Jun, 2026 |
| 12 | Leslie W. Kreis | Director, TenPercentOwner | 0 | 48,500 | 48,500 | 0.5% | 20 Jun, 2025 |
| 13 | James Michael O'Brien | Chief Financial Officer | 5,000 | 0 | 5,000 | 0.0% | 14 Oct, 2021 |
Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.
| Date | Insider | Position | Transaction | Shares | Price | Value | Shares Held After | Ownership |
|---|---|---|---|---|---|---|---|---|
| 17 Jun, 2026 | Aaron G.L. Fletcher | Director, TenPercentOwner | Acquired A | 25,000 | $0.00 | $0 | 81,229 | Direct |
| 17 Jun, 2026 | Peggy Wallace | Director | Acquired A | 25,000 | $0.00 | $0 | 111,461 | Direct |
| 17 Jun, 2026 | Jack A. Khattar | Director | Acquired A | 25,000 | $0.00 | $0 | 73,500 | Direct |
| 17 Jun, 2026 | Ellen B Richstone | Director | Acquired A | 25,000 | $0.00 | $0 | 83,500 | Direct |
| 17 Jun, 2026 | Brett P Monia | Director | Acquired A | 25,000 | $0.00 | $0 | 73,500 | Direct |
| 01 May, 2026 | John Brendan Doyle | Chief Financial Officer | Disposed F | 8,567 | $1.28 | $10.97K | 618,942 | Direct |
| 16 Apr, 2026 | John Brendan Doyle | Chief Financial Officer | Acquired P | 10,000 | $1.13 | $11.30K | 627,509 | Direct |
| 16 Apr, 2026 | Lisa Ricciardi | Ceo President | Acquired P | 9,175 | $1.10 | $10.09K | 1,715,851 | Direct |
| 16 Apr, 2026 | Anthony Caggiano | Chief Medical Officer | Acquired P | 10,000 | $1.11 | $11.10K | 874,906 | Direct |
| 15 Feb, 2026 | Lisa Ricciardi | Ceo President | Disposed F | 5,850 | $1.12 | $6.55K | 1,706,676 | Direct |
| 15 Feb, 2026 | Anthony Caggiano | Chief Medical Officer | Disposed F | 4,680 | $1.12 | $5.24K | 864,906 | Direct |
| 15 Feb, 2026 | John Brendan Doyle | Chief Financial Officer | Disposed F | 1,560 | $1.12 | $1.75K | 617,509 | Direct |
| 03 Feb, 2026 | John Brendan Doyle | Chief Financial Officer | Acquired A | 200,000 | $0.00 | $0 | 645,990 | Direct |
| 03 Feb, 2026 | Anthony Caggiano | Chief Medical Officer | Acquired A | 400,000 | $0.00 | $0 | 907,993 | Direct |
| 03 Feb, 2026 | Lisa Ricciardi | Ceo President | Acquired A | 800,000 | $0.00 | $0 | 1,790,266 | Direct |
| 03 Feb, 2026 | Anthony Caggiano | Chief Medical Officer | Disposed F | 11,488 | $1.12 | $12.87K | 896,505 | Direct |
| 04 Feb, 2026 | John Brendan Doyle | Chief Financial Officer | Disposed F | 26,921 | $1.03 | $27.73K | 619,069 | Direct |
| 03 Feb, 2026 | Lisa Ricciardi | Ceo President | Disposed F | 26,036 | $1.12 | $29.16K | 1,764,230 | Direct |
| 04 Feb, 2026 | Anthony Caggiano | Chief Medical Officer | Disposed F | 26,919 | $1.03 | $27.73K | 869,586 | Direct |
| 04 Feb, 2026 | Lisa Ricciardi | Ceo President | Disposed F | 51,704 | $1.03 | $53.26K | 1,712,526 | Direct |