Celcuity Inc. (CELC) Institutional Ownership

Ownership Summary

According to SEC filings for the period ending December 2025, Celcuity Inc. (NASDAQ:CELC) is held by 229 institutional firms.

• The percentage of Celcuity owned by institutions changed from 89.6% in September 2025 to 106.7% in December 2025, marking a slight up trend.
• The company experienced a 26.18% quarterly change in institutional shares held, alongside an increase of 120.19% in total owners annually.
• A review of institutional activity for Celcuity shows 158 of 229 filers increasing their positions, while 58 reduced their stake, and 13 remained unchanged.
• Collectively, institutional investors increased their stake in Celcuity to 47.04Mn shares as of December 2025, a change that is up by 9.76Mn shares quarter on quarter and up 16.66Mn shares year over year.
• With 7.92Mn shares, BAKER BROS. ADVISORS LP commands the largest institutional position in Celcuity as of December 31, 2025, equating to 17.95% of the company.
• Among the most significant buyers of Celcuity during December 2025 were Avoro Capital Advisors LLC (3.11Mn), NEA Management Company, LLC (1.39Mn), DEERFIELD MANAGEMENT COMPANY, L.P. (980.47K), STATE STREET CORP (914.89K), Holocene Advisors, LP (695.34K).
• Leading sellers of Celcuity stock in December 2025 included EVENTIDE ASSET MANAGEMENT, LLC (775.12K), UBS Group AG (772.91K), MILLENNIUM MANAGEMENT LLC (424.37K), D. E. Shaw & Co., Inc. (314.29K), Sio Capital Management, LLC (309.46K).
• The top 10 institutional holders of Celcuity for the quarter ending December 2025 included BAKER BROS. ADVISORS LP (7.92Mn), NEA Management Company, LLC (3.54Mn), PERCEPTIVE ADVISORS LLC (3.16Mn), Avoro Capital Advisors LLC (3.11Mn), BlackRock, Inc. (2.54Mn), VANGUARD GROUP INC (2.28Mn), Soleus Capital Management, L.P. (1.81Mn), DEERFIELD MANAGEMENT COMPANY, L.P. (1.71Mn), STATE STREET CORP (1.64Mn), MORGAN STANLEY (1.40Mn).