CalciMedica, Inc. (CALC) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

15,007,692Shares Outstanding

2,662,713Shares held by institutions

$1,624,255Value of institutional holdings

24.22%Institutional ownership %

5.03%Shares Changed QoQ

29No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

The institutional landscape for CalciMedica, Inc. (NASDAQ:CALC) includes 29 filers as of the latest reporting cycle ending December 2025.

These investors collectively held 24.2% of the company's total shares outstanding in December 2025, up from 23.7% in September 2025.
On a quarter-over-quarter basis, institutional holdings shifted by 5.03%, with a year-over-year a decrease of 6.45% in the count of filers.
The latest 13F cycle for CalciMedica reveals that of 29 total investors, 11 funds grew their exposure, whereas 8 reduced theirs and 10 made no changes.
The total number of shares held by institutions in CalciMedica increased to 3.63Mn as of December 2025, a net change of up by 174.18K shares quarter on quarter, and down 629.23K shares year over year.
DEERFIELD MANAGEMENT COMPANY, L.P. continues to be the largest institutional holder of CalciMedica as of December 31, 2025, with a position of 1.30Mn shares, representing 8.66% of the company's outstanding stock.
Among the most significant buyers of CalciMedica during December 2025 were BOOTHBAY FUND MANAGEMENT, LLC (76.86K), PVG ASSET MANAGEMENT CORP (45.83K), VANGUARD GROUP INC (31.18K), JANE STREET GROUP, LLC (19.20K), RENAISSANCE TECHNOLOGIES LLC (18.30K).
Leading sellers of CalciMedica stock in December 2025 included MILLENNIUM MANAGEMENT LLC (19.53K), ENVESTNET ASSET MANAGEMENT INC (13.52K), 180 WEALTH ADVISORS, LLC (10.85K), Atria Investments, Inc (9.30K), Cetera Investment Advisers (3.08K).
The top 10 institutional holders of CalciMedica for the quarter ending December 2025 included DEERFIELD MANAGEMENT COMPANY, L.P. (1.30Mn), Soleus Capital Management, L.P. (683.90K), Aisling Capital Management LP (521.11K), VANGUARD GROUP INC (407.80K), GEODE CAPITAL MANAGEMENT, LLC (99.79K), RENAISSANCE TECHNOLOGIES LLC (88.30K), BOOTHBAY FUND MANAGEMENT, LLC (76.86K), ENVESTNET ASSET MANAGEMENT INC (63.19K), MERITAGE PORTFOLIO MANAGEMENT (61.54K), Stonehage Fleming Financial Services Holdings Ltd (53.70K).

29 Institutional Holders

2,662,713 Total Shares Held

Rows:

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Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
DEERFIELD MANAGEMENT COMPANY, L.P.	31 Dec, 2025	1,300,000	0	0.00%	$8,567,000.00
Soleus Capital Management, L.P.	31 Dec, 2025	683,904	0	0.00%	$4,506,927.00
Aisling Capital Management LP	31 Dec, 2025	521,114	0	0.00%	$3,434,141.00
VANGUARD GROUP INC	31 Dec, 2025	407,801	31,177	8.28%	$2,687,408.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	99,787	935	0.95%	$657,595.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	88,300	18,300	26.14%	$581,897.00
BOOTHBAY FUND MANAGEMENT, LLC	31 Dec, 2025	76,855	76,855	0.00%	$506,474.00
ENVESTNET ASSET MANAGEMENT INC	31 Dec, 2025	63,186	-13,519	-17.62%	$416,396.00
MERITAGE PORTFOLIO MANAGEMENT	31 Dec, 2025	61,539	0	0.00%	$405,542.00
Stonehage Fleming Financial Services Holdings Ltd	31 Dec, 2025	53,703	0	0.00%	$353,902.00
PVG ASSET MANAGEMENT CORP	31 Dec, 2025	45,830	45,830	0.00%	$302,019.00
Summit Financial, LLC	31 Dec, 2025	35,484	10,392	41.42%	$233,840.00
180 WEALTH ADVISORS, LLC	31 Dec, 2025	31,850	-10,850	-25.41%	$209,892.00
Atria Investments, Inc	31 Dec, 2025	28,781	-9,305	-24.43%	$189,667.00
Cetera Investment Advisers	31 Dec, 2025	22,290	-3,075	-12.12%	$146,891.00
JANE STREET GROUP, LLC	31 Dec, 2025	19,203	19,203	0.00%	$126,548.00
J. Goldman & Co LP	31 Dec, 2025	18,900	0	0.00%	$124,551.00
TritonPoint Partners, LLC	31 Dec, 2025	15,119	15,119	0.00%	$99,634.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	14,855	-19,533	-56.80%	$97,894.00
FIRST MANHATTAN CO. LLC.	31 Dec, 2025	13,226	0	0.00%	$87,159.00

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