Aytu Biopharma, Inc (AYTU) Institutional Ownership

Ownership Summary

Aytu Biopharma, Inc (NASDAQ:AYTU) is held by 39 institutional investors per 13F filings through December 2025.

• Collectively, these holders controlled 37.6% of Aytu Biopharma's outstanding shares in December 2025, up from 18.7% in September 2025.
• Their total shares held in AYTU increased 4.03% from the prior quarter, while the number of investors in Aytu Biopharma increased 34.48% year over year.
• Among the 39 funds, 16 bought more Aytu Biopharma shares, 8 sold down, and 15 held their ground.
• Altogether, these fund groups held 3.77Mn shares in AYTU by December 2025, up by 146.06K shares quarter on quarter, and up 1.89Mn shares year over year.
• As of December 31, 2025, the biggest holder of Aytu Biopharma is Nantahala Capital Management, LLC at 1.09Mn shares, representing 10.83% of shares outstanding.
• Top purchasers of AYTU stock for the quarter ending December 2025 included VANGUARD CAPITAL MANAGEMENT LLC (261.15K), CROWN ADVISORS MANAGEMENT, INC. (145.0K), Arete Wealth Advisors, LLC (49.55K), DIADEMA PARTNERS LP (47.29K), VANGUARD FIDUCIARY TRUST CO (47.05K).
• Leading sellers of Aytu Biopharma shares for the quarter ending December 2025 were FNY Investment Advisers, LLC (31.51K), Stonepine Capital Management, LLC (21.42K), XTX Topco Ltd (4.28K), UBS Group AG (1.39K), Tower Research Capital LLC (TRC) (149).
• Per Business Quant, the top 10 investors in AYTU for the quarter ending December 2025 include Nantahala Capital Management, LLC (1.09Mn), Stonepine Capital Management, LLC (792.29K), AWM Investment Company, Inc. (619.57K), DIADEMA PARTNERS LP (353.08K), VANGUARD CAPITAL MANAGEMENT LLC (261.15K), CROWN ADVISORS MANAGEMENT, INC. (145.0K), TWO SIGMA INVESTMENTS, LP (121.97K), RENAISSANCE TECHNOLOGIES LLC (93.72K), Persistent Asset Partners Ltd (92.9K), GEODE CAPITAL MANAGEMENT, LLC (92.64K).