Aytu Biopharma, Inc (AYTU) Institutional Ownership

Ownership Summary

Recent 13F filings as of September 2025 show that 33 institutional investors hold a position in Aytu Biopharma, Inc (NASDAQ:AYTU).

• Institutional ownership in Aytu Biopharma edged up to 56.7% in September 2025, compared to 33.4% in June 2025.
• The company experienced a 26.84% quarterly change in institutional shares held, alongside an increase of 26.92% in total owners annually.
• During the quarter, 15 institutions bought more Aytu Biopharma shares, 3 sold shares, and 15 of the 33 total investors held their position steady.
• The aggregate institutional position in Aytu Biopharma now stands at 3.58Mn shares as of September 2025, after investors increased their holdings (up by 757.61K shares quarter on quarter which is up 1.53Mn shares year over year).
• Nantahala Capital Management, LLC continues to be the largest institutional holder of Aytu Biopharma as of September 30, 2025, with a position of 1.09Mn shares, representing 17.21% of the company's outstanding stock.
• Among the most significant buyers of Aytu Biopharma during September 2025 were DIADEMA PARTNERS LP (272.67K), VANGUARD GROUP INC (250.69K), Stonepine Capital Management, LLC (79.18K), Persistent Asset Partners Ltd (62.45K), TWO SIGMA ADVISERS, LP (39.80K).
• Leading sellers of Aytu Biopharma stock in September 2025 included FNY Investment Advisers, LLC (35.79K), AWM Investment Company, Inc. (300), SBI Securities Co., Ltd. (149).
• The top 10 institutional holders of Aytu Biopharma for the quarter ending September 2025 included Nantahala Capital Management, LLC (1.09Mn), Stonepine Capital Management, LLC (891.86K), AWM Investment Company, Inc. (619.57K), VANGUARD GROUP INC (278.58K), DIADEMA PARTNERS LP (272.67K), RENAISSANCE TECHNOLOGIES LLC (95.12K), GEODE CAPITAL MANAGEMENT, LLC (71.01K), TWO SIGMA INVESTMENTS, LP (68.74K), Persistent Asset Partners Ltd (62.45K), TWO SIGMA ADVISERS, LP (39.80K).