Annexon, Inc. (ANNX) Institutional Ownership

Ownership Summary

According to SEC filings for the period ending September 2025, Annexon, Inc. (NASDAQ:ANNX) is held by 144 institutional firms.

• These investors collectively held 92.1% of the company's total shares outstanding in September 2025, up from 88.3% in June 2025.
• On a quarter-over-quarter basis, institutional holdings shifted by 6.85%, with a year-over-year an increase of 2.13% in the count of filers.
• Among the 144 institutional holders of Annexon, 77 added to their stakes while 43 trimmed their positions and 24 held steady.
• The total number of shares held by institutions in Annexon increased to 101.26Mn as of September 2025, a net change of up by 6.49Mn shares quarter on quarter, and down 8.85Mn shares year over year.
• FMR LLC continues to be the largest institutional holder of Annexon as of September 30, 2025, with a position of 11.08Mn shares, representing 10.08% of the company's outstanding stock.
• Among the most significant buyers of Annexon during September 2025 were Opaleye Management Inc. (2.60Mn), MORGAN STANLEY (2.20Mn), Woodline Partners LP (1.58Mn), BALYASNY ASSET MANAGEMENT L.P. (1.20Mn), DEUTSCHE BANK AG\ (992.90K).
• Leading sellers of Annexon stock in September 2025 included FMR LLC (4.61Mn), ADAGE CAPITAL PARTNERS GP, L.L.C. (1.34Mn), TFG Asset Management GP Ltd (537.54K), KENNEDY CAPITAL MANAGEMENT LLC (215.11K), BANK OF AMERICA CORP /DE/ (158.49K).
• The top 10 institutional holders of Annexon for the quarter ending September 2025 included FMR LLC (11.08Mn), BlackRock, Inc. (7.90Mn), BVF INC/IL (7.00Mn), Redmile Group, LLC (6.30Mn), VANGUARD GROUP INC (5.84Mn), Bain Capital Life Sciences Investors, LLC (5.25Mn), Bellevue Group AG (5.16Mn), MORGAN STANLEY (3.03Mn), MILLENNIUM MANAGEMENT LLC (2.82Mn), Woodline Partners LP (2.64Mn).