Annexon, Inc. (ANNX) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

0Shares Outstanding

30,140,611Shares held by institutions

$149,346,728Value of institutional holdings

65.19%Institutional ownership %

-1.61%Shares Changed QoQ

125No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Annexon, Inc. (NASDAQ:ANNX) is held by 161 institutional investors per 13F filings through December 2025.

These investors collectively held 91.2% of Annexon's outstanding shares in December 2025, up from 68.8% in September 2025.
They increased total shares held in Annexon by 39.62% from the prior quarter, while the number of investors in ANNX increased 7.33% year over year.
Among the 161 funds, 105 bought more Annexon shares, 32 sold down, and 24 held their ground.
Institutional investors collectively held 135.93Mn shares in Annexon as of December 2025, up by 38.57Mn shares quarter on quarter, and up 21.1Mn shares year over year.
FMR LLC holds the largest position in ANNX at 10.22Mn shares as of December 31, 2025, or 6.86% of shares outstanding.
The biggest buyers of Annexon for the quarter ending December 2025 included ADAGE CAPITAL PARTNERS GP, L.L.C. (4.0Mn), Redmile Group, LLC (3.75Mn), Longaeva Partners L.P. (3.1Mn), MAK CAPITAL ONE LLC (2.96Mn), State Street Corp (2.6Mn).
The biggest sellers of Annexon for the quarter ending December 2025 included Bank Of America Corp /De/ (983.02K), DEUTSCHE BANK AG\ (943.6K), FMR LLC (858.69K), Goldman Sachs Group Inc (637.69K), SPHERA FUNDS MANAGEMENT LTD. (478.18K).
Annexon's 10 largest shareholders as of December 2025 include FMR LLC (10.22Mn), Redmile Group, LLC (10.05Mn), BVF INC/IL (9.13Mn), BlackRock, Inc. (8.96Mn), VANGUARD GROUP INC (7.75Mn), ADAGE CAPITAL PARTNERS GP, L.L.C. (5.5Mn), Bain Capital Life Sciences Investors, LLC (5.25Mn), Bellevue Group AG (5.16Mn), State Street Corp (4.65Mn), Ameriprise Financial Inc (4.35Mn) per Business Quant data.

161 Institutional Holders

30,140,611 Total Shares Held

Rows:

Download Data

Owner Name	Date	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	1,061,426	13.44%	$0.00
FMR LLC	31 Dec, 2025	-858,693	-7.75%	$0.00
Bain Capital Life Sciences Investors, LLC	31 Dec, 2025	0	0.00%	$0.00
Barclays Plc	31 Dec, 2025	-35,732	-10.97%	$0.00
Redmile Group, LLC	31 Dec, 2025	3,750,000	59.52%	$0.00
Bellevue Group AG	31 Dec, 2025	0	0.00%	$0.00
HSBC HOLDINGS PLC	31 Dec, 2025	25,581	99.46%	$0.00
BVF INC/IL	31 Dec, 2025	2,128,080	30.40%	$0.00
Woodline Partners LP	31 Dec, 2025	1,361,799	51.62%	$0.00
Rockefeller Capital Management L.P.	31 Dec, 2025	668	0.00%	$0.00
VANGUARD GROUP INC	31 Dec, 2025	1,918,275	32.87%	$0.00
Longaeva Partners L.P.	31 Dec, 2025	3,100,000	0.00%	$0.00
ADAGE CAPITAL PARTNERS GP, L.L.C.	31 Dec, 2025	4,000,000	266.67%	$0.00
Nuveen, LLC	31 Dec, 2025	2,232,766	327.12%	$0.00
State Street Corp	31 Dec, 2025	2,601,877	126.90%	$0.00
Qube Research & Technologies Ltd	31 Dec, 2025	1,808,835	315.87%	$0.00
Ameriprise Financial Inc	31 Dec, 2025	2,156,428	98.36%	$0.00
Ishara Investments LP	31 Dec, 2025	750,000	0.00%	$0.00
BALYASNY ASSET MANAGEMENT L.P.	31 Dec, 2025	2,001,996	154.32%	$0.00
Russell Investments Group, Ltd.	31 Dec, 2025	664,796	3,648.72%	$0.00

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