Acrivon Therapeutics, Inc. (ACRV) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

38,795,745Shares Outstanding

11,868,146Shares held by institutions

$18,989,034Value of institutional holdings

47.92%Institutional ownership %

7.07%Shares Changed QoQ

47No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

The institutional landscape for Acrivon Therapeutics, Inc. (NASDAQ:ACRV) includes 47 filers as of the latest reporting cycle ending December 2025.

These investors collectively held 47.9% of the company's total shares outstanding in December 2025, up from 45.0% in September 2025.
In percentage terms, this reflects as a holdings change of 7.07% quarter on quarter, and a decrease of 25.40% year over year.
Among the 47 institutional holders of Acrivon Therapeutics, 24 added to their stakes while 9 trimmed their positions and 14 held steady.
Collectively, institutional investors increased their stake in Acrivon Therapeutics to 18.59Mn shares as of December 2025, a change that is up by 1.23Mn shares quarter on quarter and down 4.66Mn shares year over year.
RA CAPITAL MANAGEMENT, L.P.'s holding of 8.34Mn shares as of December 31, 2025 makes it the primary institutional investor in Acrivon Therapeutics, owning 21.50% of the stock.
Among the most significant buyers of Acrivon Therapeutics during December 2025 were ACADIAN ASSET MANAGEMENT LLC (489.20K), MARSHALL WACE, LLP (346.37K), TWO SIGMA INVESTMENTS, LP (265.86K), TWO SIGMA ADVISERS, LP (197.27K), CITADEL ADVISORS LLC (100.56K).
Leading sellers of Acrivon Therapeutics stock in December 2025 included UBS Group AG (334.68K), BlackRock, Inc. (125.83K), Squarepoint Ops LLC (78.16K), MILLENNIUM MANAGEMENT LLC (63.71K), MORGAN STANLEY (10.33K).
The top 10 institutional holders of Acrivon Therapeutics for the quarter ending December 2025 included RA CAPITAL MANAGEMENT, L.P. (8.34Mn), Sands Capital Alternatives, LLC (2.12Mn), CITADEL ADVISORS LLC (1.64Mn), WELLINGTON MANAGEMENT GROUP LLP (888.13K), VANGUARD GROUP INC (698.86K), RENAISSANCE TECHNOLOGIES LLC (634.17K), TWO SIGMA INVESTMENTS, LP (585.07K), ACADIAN ASSET MANAGEMENT LLC (581.21K), MARSHALL WACE, LLP (496.08K), ACORN CAPITAL ADVISORS, LLC (405.24K).

47 Institutional Holders

11,868,146 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
RA CAPITAL MANAGEMENT, L.P.	31 Dec, 2025	8,340,508	0	0.00%	$20,100,624.00
Sands Capital Alternatives, LLC	31 Dec, 2025	2,122,605	0	0.00%	$5,115,478.00
CITADEL ADVISORS LLC	31 Dec, 2025	1,641,884	100,558	6.52%	$3,956,941.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	888,130	0	0.00%	$2,140,393.00
VANGUARD GROUP INC	31 Dec, 2025	698,857	72,709	11.61%	$1,684,246.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	634,169	10,769	1.73%	$1,528,347.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	585,069	265,864	83.29%	$1,410,016.00
ACADIAN ASSET MANAGEMENT LLC	31 Dec, 2025	581,208	489,204	531.72%	$1,400.00
MARSHALL WACE, LLP	31 Dec, 2025	496,081	346,366	231.35%	$1,195,556.00
ACORN CAPITAL ADVISORS, LLC	31 Dec, 2025	405,237	0	0.00%	$976,622.00
UBS Group AG	31 Dec, 2025	348,541	-334,677	-48.99%	$839,984.00
JANE STREET GROUP, LLC	31 Dec, 2025	342,071	52,823	18.26%	$824,391.00
TWO SIGMA ADVISERS, LP	31 Dec, 2025	333,773	197,273	144.52%	$804,393.00
BlackRock, Inc.	31 Dec, 2025	205,124	-125,833	-38.02%	$494,349.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	198,223	6,190	3.22%	$477,891.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	121,524	-63,710	-34.39%	$292,873.00
GOLDMAN SACHS GROUP INC	31 Dec, 2025	119,422	99,680	504.91%	$287,807.00
STATE STREET CORP	31 Dec, 2025	67,145	0	0.00%	$161,819.00
NORTHERN TRUST CORP	31 Dec, 2025	63,718	21,552	51.11%	$153,561.00
PRELUDE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	48,015	48,015	0.00%	$115,716.00

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