JNJ
2nd
Johnson & Johnson
$653,395.82 Mn
271.13
+3.32%
+53.83%
The MedTech segment designs and manufactures therapeutic and surgical medical devices, including cardiovascular devices, orthopaedic implants, and robotic surgical technologies. These products are sold to hospitals and clinicians for use in acute and elective procedures.
TMO
Thermo Fisher Scientific
$217,832.92 Mn
589.14
+0.61%
+20.84%
The company's Life Sciences Solutions and Analytical Instruments segments provide a vast portfolio of reagents, instruments, and consumables for biological and medical research, genomic and proteomic analysis, and electron microscopy. These products are sold to universities, research institutions, and biotech firms to support scientific research and bioproduction.
ABT
Abbott Laboratories
$194,996.90 Mn
112.69
+2.07%
-13.50%
Abbott develops and sells a wide range of therapeutic medical devices, including pacemakers, defibrillators, stents, and glucose monitors, sold to hospitals and physicians.
DHR
Danaher
$140,348.04 Mn
199.67
-1.47%
-4.47%
Danaher's Life Sciences and Biotechnology segments provide instruments, consumables, and software for bioprocessing, genomics, and proteomics used in laboratory research and biopharmaceutical manufacturing. These products are sold to research institutions and biotech companies to study biological molecules like DNA and RNA.
ISRG
Intuitive Surgical
$138,438.60 Mn
391.18
+0.22%
-18.72%
Intuitive Surgical designs and manufactures robotic assisted surgical systems, specifically the da Vinci and Ion platforms, which are used for minimally invasive procedures. These are therapeutic and surgical medical devices sold to hospitals and ambulatory surgery centers.
MDT
Medtronic
$117,891.52 Mn
92.09
+1.64%
-0.78%
Medtronic designs and manufactures a vast array of therapeutic and surgical medical devices, including implantable cardiac pacemakers, defibrillators, spinal implants, and robotic-assisted surgery systems. These products are sold to hospitals and physicians for the treatment of cardiovascular, neuroscience, and surgical conditions.
MCK
2nd
Mckesson
$101,353.17 Mn
869.31
+1.08%
+29.52%
Through its Medical-Surgical Solutions segment, the company manufactures and sells its own proprietary line of medical-surgical supplies and consumables to physician offices and surgery centers.
BSX
Boston Scientific
$73,157.11 Mn
50.48
-1.87%
-51.01%
Boston Scientific designs and manufactures therapeutic and surgical medical devices, including stent systems, catheters, implantable pacemakers, and neurostimulation platforms. These products are sold to hospitals and clinics for use in cardiovascular, respiratory, digestive, oncological, neurological, and urological conditions.
BRKRP
Bruker
$64,020.24 Mn
420.21
-1.39%
—
Bruker's core business is the development and manufacture of high-performance scientific instruments for life sciences research, including mass spectrometry (timsTOF), nuclear magnetic resonance (NMR) systems, and spatial biology platforms (CosMx). These tools are sold to academic, government, pharmaceutical, and biotechnology customers for molecular and cellular research.
TEL
2nd
TE Connectivity
$59,338.63 Mn
204.96
-5.73%
+0.62%
The company manufactures interventional medical components and products for medical imaging, diagnostic, surgical, and minimally invasive applications.
AME
2nd
Ametek
$57,313.02 Mn
249.99
-1.68%
+36.89%
The Electromechanical group designs and manufactures medical devices, including surgical instruments and implantable devices, sold to medical device makers.
CAH
2nd
Cardinal Health
$54,655.30 Mn
235.00
-0.28%
+56.95%
The company manufactures and sells its own branded medical-surgical and laboratory products, specifically mentioning gloves, syringes, wound care items, and surgical drapes.
EW
Edwards Lifesciences
$52,476.37 Mn
91.01
+0.20%
+16.23%
Edwards Lifesciences designs and manufactures therapeutic and surgical medical devices, specifically heart valves. Its revenue is driven by the sale of the SAPIEN family of transcatheter valves, the PASCAL and EVOQUE repair/replacement systems, and surgical tissue valves like INSPIRIS RESILIA.
BDX
Becton Dickinson
$49,255.71 Mn
180.83
-0.71%
-7.27%
BD's Medical Essentials segment produces a vast array of consumables and disposables, including peripheral intravenous catheters, safety hypodermic syringes, needles, and sharps disposal systems. These products represent a core part of their revenue stream and match the description of medical supplies and consumables.
MDLN
Medline
$44,845.83 Mn
34.12
-2.18%
—
Medline manufactures and sells a vast array of medical supplies and consumables, including wound care, exam gloves, protective apparel, and surgical procedure trays. These products are sold to hospitals, surgery centers, and physician offices as their core business.
IDXX
2nd
Idexx Laboratories
$43,642.56 Mn
553.32
+1.32%
-13.25%
Idexx manufactures and sells clinical diagnostic equipment and tests, including point-of-care analyzers and water testing instrumentation like Colilert and Colisure for water utilities and government laboratories.
A
Agilent Technologies
$41,892.46 Mn
148.44
+0.00%
+25.64%
Agilent designs and manufactures life-sciences research tools and instruments, including liquid chromatography, gas chromatography, and mass spectrometry systems. These products are sold to pharmaceutical, biotechnology, and academic research institutions for drug discovery and chemical analysis.
WAT
Waters
$39,411.80 Mn
401.24
-1.59%
+38.65%
Waters Corporation designs and manufactures analytical instruments, including HPLC, UPLC, and mass spectrometry systems, as well as chromatography columns and reagents. These products are sold as tools for life-sciences research and bioproduction to customers in pharmaceuticals, biotechnology, and academic research.
ALC
Alcon
$35,554.07 Mn
73.55
+1.50%
-16.54%
Alcon's primary business involves the design and manufacture of therapeutic and surgical medical devices, specifically intraocular lenses (IOLs), phacoemulsification systems, and 3D visualization platforms for cataract and glaucoma surgeries.
DXCM
Dexcom
$33,815.04 Mn
89.60
+0.95%
+10.86%
Dexcom designs and manufactures continuous glucose monitoring (CGM) systems, including the G7 and Stelo, which are wearable medical devices used for diabetes and metabolic health management. Revenue is primarily generated from the sale of this hardware, including sensors, transmitters, and receivers.
GEHC
GE HealthCare Technologies
$32,805.97 Mn
72.63
+0.36%
-0.74%
The company's largest segments, Imaging and Advanced Visualization Solutions, focus on manufacturing clinical diagnostic equipment such as CT, MRI, X-ray, and Ultrasound systems. These products are sold to hospitals and health systems for the purpose of clinical diagnosis.
RMD
Resmed
$31,735.59 Mn
220.02
-0.14%
-23.10%
ResMed designs and manufactures therapeutic medical devices for sleep apnea and respiratory disorders, specifically CPAP, APAP, bilevel, and high flow therapy systems. These are regulated treatment devices sold to patients, hospitals, and home medical equipment providers.
IR
2nd
Ingersoll Rand
$31,338.71 Mn
80.77
-1.87%
+2.38%
The Precision and Science Technologies segment designs and manufactures life science tools and single-use powder and liquid handling containment solutions for life science and medical applications.
MTD
2nd
Mettler Toledo International
$30,350.39 Mn
1,399.68
-1.23%
+6.74%
Mettler-Toledo designs and manufactures laboratory instruments, including balances, pipettes, and analyzers, which contribute approximately 56% of net sales and are used in life sciences research and development.
ILMN
Illumina
$28,431.79 Mn
188.29
-2.51%
+87.30%
Illumina designs and manufactures sequencing and array-based instruments, reagents, and library preparation kits used for genomics and proteomics research. Its primary revenue comes from selling these life-sciences research tools and consumables to research institutions, academic centers, and biotechnology companies.
WST
West Pharmaceutical Services
$24,408.38 Mn
346.71
+0.07%
+42.63%
The company's primary business is the manufacture of primary proprietary packaging solutions for injectable drugs, specifically elastomer-based containment components such as stoppers, seals, plungers, and cartridge components. These are medical supplies and consumables sold to pharmaceutical and biologic companies for use in their injectable formulations.
STE
Steris
$22,659.98 Mn
232.41
+1.18%
-4.97%
STERIS manufactures capital equipment for healthcare providers, including sterilizers, surgical tables, and automated endoscope reprocessors. These are therapeutic and surgical medical devices used in operating rooms and procedural centers.
EXAS
2nd
Exact Sciences
$20,017.07 Mn
104.91
+0.95%
+136.92%
The company develops and commercializes the proprietary molecular and blood-based testing platforms and biomarker algorithms used to run its diagnostic tests. This includes the development of the Cologuard and Oncodetect platforms.
ZBH
Zimmer Biomet Holdings
$18,919.27 Mn
99.19
+1.03%
-3.29%
Zimmer Biomet designs and manufactures therapeutic and surgical medical devices, specifically orthopedic reconstructive implants, knee and hip replacement systems, and thoracic devices. These products are sold to orthopedic surgeons, neurosurgeons, and hospitals for use in surgical procedures.
FTV
2nd
Fortive
$17,989.57 Mn
59.45
-1.95%
+24.50%
The Advanced Healthcare Solutions segment designs and manufactures therapeutic and surgical medical devices, including instrument sterilization systems and radiation detection and safety monitoring tools under brands like ASP and Landauer.
IEX
2nd
Idex
$17,260.78 Mn
234.14
-2.59%
+42.96%
The Health & Science Technologies segment specifically produces biocompatible medical devices and implantables sold to medical device makers.
NDSN
2nd
Nordson
$16,949.96 Mn
304.21
-1.81%
+42.09%
The Medical Interventional Solutions business provides therapeutic and surgical medical devices, including interventional delivery systems, balloons, and cardiovascular cannula for minimally invasive surgical procedures.
SOLV
Solventum
$14,869.63 Mn
87.41
+0.63%
+23.53%
Solventum's MedSurg segment sells therapeutic and surgical medical devices, including negative pressure wound therapy and surgical supplies. These products are designed to accelerate healing and mitigate patient risk during surgical operations.
COO
Cooper Companies
$14,765.62 Mn
75.76
+0.88%
+3.03%
The company designs and manufactures therapeutic and surgical medical devices, including soft contact lenses (CooperVision) and surgical devices for gynecologic procedures and contraceptive products like Paragard (CooperSurgical). These products are sold to eye care practitioners, hospitals, and ambulatory surgery centers.
MOG-B
2nd
Moog
$14,126.34 Mn
445.95
-0.90%
+118.87%
Moog manufactures medical devices and components, specifically pumps and sets for enteral clinical nutrition and infusion therapy, as well as components for surgical handpieces.
BAX
Baxter International
$13,405.71 Mn
25.93
+0.04%
+9.83%
Baxter's core business involves the manufacture of medical supplies and consumables, specifically sterile intravenous (IV) solutions, infusion systems, administration sets, and parenteral nutrition therapies. These products are sold as disposables and consumables to hospitals and healthcare providers.
CRL
2nd
Charles River Laboratories International
$13,328.52 Mn
279.26
-2.61%
+77.90%
The Research Models and Services segment supplies purpose-bred rodents, large research models, and cell solutions used by clients for drug discovery and development activities.
PEN
Penumbra
$12,799.99 Mn
324.96
-0.68%
+27.26%
Penumbra designs and manufactures therapeutic and surgical medical devices, specifically for vascular and neurovascular conditions. Its product portfolio includes the INDIGO system for thrombectomy and the RUBY embolization platform, which are used by physicians in hospitals to remove blood clots and treat aneurysms.
RVTY
Revvity
$12,687.10 Mn
113.70
-2.10%
+26.77%
Revvity's Life Sciences segment sells a comprehensive portfolio of research tools, including radiometric detection reagents, microscopy imaging reagents, recombinant cell lines, and automated liquid handling platforms to pharmaceutical, biotech, and academic researchers.
ALGN
Align Technology
$11,962.75 Mn
167.91
-1.90%
+15.85%
Align Technology's primary business is the design and manufacture of clear aligners (Invisalign) and intraoral scanners (iTero) specifically for orthodontists and dental practitioners. The company's core revenue is derived from dental-specific products and services, fitting the definition of the Dental industry.
HALO
2nd
Halozyme Therapeutics
$11,961.87 Mn
104.89
+1.83%
+52.10%
The company designs and supplies drug-device combination products, specifically auto-injectors for self-administration, to partners such as Teva.
GMED
Globus Medical
$11,602.91 Mn
86.42
+1.52%
+43.44%
Globus Medical designs and manufactures therapeutic and surgical medical devices, specifically implantable devices for spinal, orthopedic, and neurosurgical procedures such as pedicle screw systems and interbody spacers. It also sells spinal cord stimulation systems and robotics platforms like ExcelsiusGPS for surgical guidance.
TECH
Bio-Techne
$11,303.59 Mn
72.22
-0.23%
+35.52%
Bio-Techne's Protein Sciences segment sells high-quality biological reagents such as cytokines, growth factors, and antibodies, as well as proteomic analytical tools like western blot systems and multiplexed ELISA platforms for life science research and drug discovery.
DCI
2nd
Donaldson
$10,895.64 Mn
94.00
-0.72%
+26.92%
The Life Sciences segment sells bioprocessing equipment such as bioreactors and fermenters, as well as consumables including chromatography devices and reagents used for cell growth, separation, and purification.
GKOS
Glaukos
$10,839.88 Mn
184.17
-0.78%
+105.73%
Glaukos generates the majority of its revenue from the sale of medical devices, specifically the iStent family of micro scale surgical devices used in Micro Invasive Glaucoma Surgery (MIGS). These products are sold directly to ambulatory surgery centers, hospitals, and physician private practices.
PODD
Insulet
$10,266.50 Mn
148.03
+5.96%
-54.18%
Insulet designs and manufactures the Omnipod platform, which consists of tubeless insulin delivery pods and controllers used for the treatment of insulin-dependent diabetes. These are therapeutic medical devices sold to wholesalers, distributors, and consumers.
HSIC
2nd
Henry Schein
$9,986.28 Mn
89.23
-0.32%
+32.74%
The Global Specialty Products segment manufactures and sells dental implants, biomaterials, and orthodontic products, competing directly with dental-specific firms like Straumann and Dentsply Sirona.
RGEN
Repligen
$9,375.36 Mn
166.15
-1.71%
+33.91%
Repligen provides bioprocessing technologies, instruments, and consumables used in the manufacturing of biological drugs, such as XCell ATF cell retention systems and OPUS PrePacked Columns. Its revenue is generated from the sale of these life-sciences research and bioproduction tools to biopharmaceutical companies and CDMOs.
BIO
Bio-Rad Laboratories
$8,876.13 Mn
352.16
-0.85%
+23.72%
Bio-Rad's Life Science segment develops and markets instruments, systems, reagents, and consumables used to separate, purify, and quantify biological materials for research and biopharmaceutical manufacturing. These products are sold to universities, medical schools, and biotechnology companies for use in laboratory environments.
ATR
2nd
Aptargroup
$8,376.18 Mn
131.74
+0.01%
-4.46%
The company's Pharma segment produces therapeutic delivery devices, including nasal drug delivery spray pumps, metered dose inhaler valves, and digital health solutions for oncology and neurology.
GIFLF
2nd
Grifols
$8,002.83 Mn
11.76
+0.00%
-15.40%
The company has a dedicated Diagnostic segment that develops and sells in vitro diagnostic assays, nucleic acid testing platforms, and immunohematology analyzers for blood typing and infectious disease screening.
SATA
2nd
Strive
$7,940.31 Mn
99.69
+0.21%
—
Through its subsidiary Semler Scientific, the company markets the QuantaFlo FDA cleared vascular testing device, which is a sensor-based product used for in-office blood flow tests. Revenue is derived from licensing fees and service agreements tied to the volume of tests performed using this diagnostic equipment.
OKLO
2nd
Oklo
$7,659.03 Mn
41.38
-5.68%
-40.02%
Through its subsidiary Atomic Alchemy, the company produces and sells radioisotopes for medical research and other applications, which falls under the manufacture of clinical diagnostic and medical-grade isotopes.
TWST
Twist Bioscience
$7,276.45 Mn
116.10
-6.68%
+314.35%
Twist Bioscience manufactures and sells synthetic genes, oligonucleotides, and next-generation sequencing tools (such as target enrichment probes and library preparation kits) used for research and bioproduction. These products are sold to biotech, pharma, and academic laboratories for applications like drug discovery and basic biological investigation.
TXG
10x Genomics
$7,247.61 Mn
55.63
-4.07%
+313.30%
10x Genomics develops and sells instruments and consumables for life-sciences research, specifically the Chromium single cell platform and Visium and Xenium spatial platforms. Its customers include academic research institutions, government laboratories, and biotechnology firms using these tools for biological analysis.
HNGE
2nd
Hinge Health
$7,075.31 Mn
88.22
+0.33%
+49.45%
The company designs and sells the Enso wearable nerve stimulation device, which is a regulated medical device used for pain relief as part of its care program.
LNTH
Lantheus Holdings
$6,543.47 Mn
100.26
-0.64%
+79.13%
Lantheus primarily generates revenue from the sale of diagnostic imaging agents such as PYLARIFY for prostate cancer PET imaging, DEFINITY for ultrasound enhancement, and Neuraceq for amyloid PET imaging. These products are sold to hospitals and independent imaging centers to facilitate clinical diagnosis.
DBVT
2nd
DBV Technologies
$6,273.26 Mn
14.47
-1.36%
+44.70%
The company designs and manufactures the Viaskin patch, a therapeutic medical device used to deliver biologically active compounds through the skin to treat allergies.
RADX
2nd
Radiopharm Theranostics
$6,196.17 Mn
2.62
-1.87%
-49.42%
The company develops diagnostic radiotracers and imaging agents, such as RAD101 for brain metastases and RAD301 for PET imaging, which are clinical diagnostic tests sold as products.
BLCO
Bausch & Lomb
$6,084.25 Mn
17.04
+0.35%
+17.84%
Bausch & Lomb manufactures a wide array of therapeutic and surgical medical devices, including intraocular lenses (enVista, Crystalens), phacoemulsification platforms (Stellaris Elite), and surgical instruments (Storz). These products are sold to hospitals, surgical centers, and eye care professionals.
NOVT
2nd
Novanta
$5,941.27 Mn
157.11
-6.90%
+30.67%
The company designs and manufactures therapeutic and surgical medical devices, specifically medical insufflators, endoscopic pumps, and integrated operating room technologies used in minimally invasive surgery.
STVN
Stevanato Group S.p.A
$5,788.27 Mn
21.20
-0.70%
-6.15%
The company's primary revenue driver (88% from the Biopharmaceutical and Diagnostic Solutions segment) comes from the sale of drug containment products such as prefillable syringes, vials, cartridges, and ampoules, which are medical supplies and consumables.
TFX
Teleflex
$5,590.61 Mn
131.94
-0.83%
+10.08%
Teleflex designs and manufactures therapeutic and surgical medical devices, including vascular catheters, interventional platforms like the MANTA Vascular Closure device, and surgical instruments such as bariatric staplers. These products are sold to hospitals and healthcare providers for use in critical care and surgical applications.
MMED
MiniMed
$5,436.68 Mn
19.36
-0.87%
—
MiniMed designs and manufactures therapeutic medical devices for diabetes management, specifically insulin pumps and smart pens. Its flagship product, the MiniMed 780G, is an automated insulin delivery system that combines pump technology with real-time glucose sensing.
MMSI
Merit Medical Systems
$5,329.71 Mn
89.26
-0.52%
+3.60%
Merit Medical Systems designs and manufactures therapeutic and surgical medical devices, including stents, balloons, and delivery systems for cardiology, radiology, and endoscopy. Their core offerings include devices for vascular access, embolotherapy, and the EsophyX Z+ system for treating gastroesophageal reflux disease.
HAE
Haemonetics
$4,759.48 Mn
104.67
+15.95%
+97.04%
Haemonetics designs and manufactures therapeutic and surgical medical devices, including vascular closure, sensor-guided technologies, and esophageal protection product lines for hospital-based interventions. It also sells capital equipment for plasma and blood collection.
ICUI
Icu Medical
$4,595.29 Mn
183.76
+0.68%
+49.45%
ICU Medical designs and manufactures therapeutic and surgical medical devices, including large volume pumps, ambulatory infusion pumps, hemodynamic monitors, and anesthesia equipment. These products are sold to acute care hospitals and clinics for use in critical care and surgical procedures.
FMCQF
2nd
Fresenius Medical Care AG
$4,562.89 Mn
51.44
+0.00%
+0.86%
The company designs and manufactures medical devices including hemodialysis machines, peritoneal dialysis cyclers, and water treatment systems sold to hospitals and clinics globally.
NVST
Envista Holdings
$4,469.50 Mn
27.83
+0.65%
+33.99%
Envista Holdings is a global dental products company that designs and manufactures dental implants, orthodontic appliances (including Spark clear aligners), and restorative materials. Its primary customers are dental professionals, including orthodontists, periodontists, and general dentists.
LIVN
LivaNova
$4,396.43 Mn
79.86
-1.99%
+49.92%
LivaNova designs and manufactures therapeutic and surgical medical devices, specifically heart-lung machines, oxygenators, and the VNS Therapy System for epilepsy and depression. These products are sold to hospitals, neurosurgeons, and perfusionists for use in surgical and clinical treatment.
ITGR
Integer Holdings
$4,252.75 Mn
125.11
+0.02%
+18.54%
Integer Holdings designs and manufactures therapeutic and surgical medical devices, including catheter-based systems, implantable pulse generators, and minimally invasive surgery tools. Its revenue is derived from selling these components and finished devices to multinational medical device original equipment manufacturers.
TLX
2nd
Telix Pharmaceuticals
$4,024.67 Mn
11.88
+1.28%
-0.17%
The company sells diagnostic imaging agents and platforms, such as Illuccix and Gozellix, which are used for prostate cancer imaging in clinical settings.
HTFL
Heartflow
$3,922.23 Mn
45.23
+7.84%
+50.92%
Heartflow sells a diagnostic test (FFR CT Analysis and Plaque Analysis) that uses AI and 3D modeling to diagnose coronary artery disease. The company generates revenue on a pay-per-click basis when physicians review these diagnostic analyses, fitting the model of selling a diagnostic test rather than performing the scan itself.
SXI
2nd
Standex International
$3,866.62 Mn
320.88
-1.68%
+57.34%
The Scientific segment manufactures medical-grade and laboratory temperature-controlled equipment, including ultra-low temperature freezers, blood bank refrigerators, and environmental stability chambers sold to healthcare facilities and laboratories.
IRTC
2nd
iRhythm Holdings
$3,796.47 Mn
115.24
-1.44%
-27.03%
The company designs and manufactures a proprietary wearable biosensor, a wire-free patch that adheres to the chest to record electrocardiogram data. This device is a regulated medical wearable that has received FDA clearance and CE marking for clinical use.
MIR
2nd
Mirion Technologies
$3,726.85 Mn
15.32
-2.73%
-25.20%
The company sells nuclear medicine products for patient dosing and medical diagnostics, as well as radiation therapy quality assurance hardware and software used in cancer centers.
OSIS
2nd
Osi Systems
$3,605.23 Mn
218.73
-4.85%
-5.40%
The Healthcare segment provides diagnostic imaging systems, ultrasound systems, and fetal Doppler devices to hospitals and clinics, which are clinical diagnostic equipment and tests.
IPGP
2nd
Ipg Photonics
$3,458.42 Mn
81.31
-7.71%
+3.09%
The company sells laser solutions specifically for medical procedures and to medical device companies, representing a material portion of its non-industrial revenue.
VCYT
2nd
Veracyte
$3,269.20 Mn
40.68
-3.33%
+35.28%
The company sells in vitro diagnostic (IVD) kits, such as Prosigna, to hospitals and laboratories outside the United States. This represents a product-based revenue stream where the customer buys the test kit to perform the analysis locally.
PLSE
Pulse Biosciences
$3,256.80 Mn
46.00
-1.69%
+193.37%
Pulse Biosciences designs and manufactures therapeutic medical devices, specifically the nPulse System and the Vybrance Percutaneous Electrode System, used for nonthermally ablating targeted cells in cardiology and soft tissue. These are surgical and treatment devices sold to hospitals and surgical centers.
GRAL
2nd
Grail
$3,166.39 Mn
70.89
+1.34%
+116.13%
The company develops and commercializes the Galleri screening tool and methylation technology, which functions as a molecular point-of-care testing platform for cancer detection.
TMDX
TransMedics
$3,140.57 Mn
90.69
+2.65%
-27.82%
TransMedics designs and manufactures the Organ Care System (OCS), a portable warm perfusion platform used for heart, lung, and liver transplantation. This is a therapeutic medical device sold to transplant centers and hospitals.
AXGN
Axogen
$2,693.01 Mn
50.19
+2.12%
+224.02%
Axogen designs and manufactures therapeutic medical devices for nerve repair, specifically the Axoguard product line (Nerve Connector, Nerve Protector, and Nerve Cap) which are cleared via the FDA 510(k) pathway. These products are sold to hospitals and surgery centers for use in surgical procedures to support nerve coaptation and neuroma prevention.
BHC
2nd
Bausch Health Companies
$2,587.40 Mn
6.92
+5.17%
-13.72%
The company sells aesthetic medical devices through Solta Medical, including laser-based skin resurfacing systems, and ophthalmic surgical equipment through Bausch + Lomb.
NEOG
Neogen
$2,518.79 Mn
11.57
-2.53%
+108.84%
Neogen's primary revenue driver is its Food Safety segment (71.3% of sales), which develops and markets diagnostic test kits for pathogen, toxin, and allergen detection, as well as culture media. These products are sold to food producers, processors, and regulatory agencies like the USDA and FDA for clinical and safety diagnostics.
UFPT
Ufp Technologies
$2,432.10 Mn
313.99
-2.28%
+43.41%
UFP Technologies designs and manufactures medical devices and components used in minimally invasive surgery, orthopedic implants, and wearables for customers like Intuitive Surgical and Stryker. While it operates as a contract partner, its primary output consists of therapeutic and surgical medical devices.
PGEN
2nd
Precigen
$2,416.56 Mn
6.75
+3.05%
+128.81%
Through its Exemplar subsidiary, the company sells genetically engineered porcine research models to academic and industry customers for use in drug discovery and preclinical studies.
CDNA
2nd
CareDx
$2,377.46 Mn
46.18
-0.43%
+289.70%
The company manufactures and sells diagnostic laboratory products and kits, including HLA typing kits like QTYPE and next-generation sequencing offerings like AlloSeq Tx, to hospitals and reference laboratories.
ATRC
AtriCure
$2,327.49 Mn
45.76
+2.21%
+28.47%
AtriCure designs and manufactures therapeutic and surgical medical devices, specifically ablation platforms like the Isolator Synergy and left atrial appendage exclusion systems like AtriClip. These products are sold to hospitals and surgical centers for use in open heart and minimally invasive cardiac procedures.
VCEL
2nd
Vericel
$2,264.83 Mn
44.26
+1.54%
+21.86%
The company sells medical technology and instruments used for the delivery of its therapies, specifically the MACI Arthro instruments used for arthroscopic delivery of the implant.
ESTA
Establishment Labs Holdings
$2,240.74 Mn
75.21
-1.84%
+96.63%
Establishment Labs designs and manufactures therapeutic and surgical medical devices, specifically the Motiva Implants silicone gel filled breast implants and the Motiva Flora tissue expander. These products are sold to hospitals, outpatient surgery centers, and plastic surgeons for use in breast aesthetics and reconstruction.
XRAY
Dentsply Sirona
$2,213.11 Mn
11.11
-0.71%
-19.84%
The company is the world's largest manufacturer of professional dental products, selling clear aligners (SureSmile), dental implants, and CAD/CAM systems (CEREC) to dental professionals and laboratories.
BFLY
Butterfly Network
$2,141.96 Mn
9.00
-0.22%
+525.00%
Butterfly Network manufactures and sells clinical diagnostic equipment, specifically handheld ultrasound devices like the Butterfly iQ3 and Butterfly iQ+, which are used for point-of-care imaging. Its revenue is driven by the sale of these diagnostic instruments and the associated AI-driven software and consumables.
NVCR
NovoCure
$2,007.47 Mn
17.24
-1.65%
+42.60%
NovoCure designs and manufactures therapeutic medical devices, specifically the Optune and Optune Lua systems, which deliver tumor treating fields therapy to patients with solid tumor cancers. Its revenue is generated primarily through the sale of these devices and associated accessory systems.
LMAT
Lemaitre Vascular
$1,996.77 Mn
81.52
-1.20%
-14.23%
Lemaitre Vascular designs and manufactures therapeutic and surgical medical devices, including anastomotic clips, carotid shunts, embolectomy catheters, and valvulotomes. These products are sold primarily to hospitals and clinics for use by vascular and cardiac surgeons in open and minimally invasive procedures.
EPAC
2nd
Enerpac Tool
$1,867.04 Mn
36.51
-1.54%
-13.91%
Through its Cortland Biomedical business, the company operates as a biomedical textile product development company, which falls under the manufacture of medical supplies and consumables.
BLFS
Biolife Solutions
$1,708.18 Mn
34.94
-1.44%
+42.61%
Biolife Solutions provides tools, reagents, and consumables for bioproduction and life-sciences research, specifically biopreservation media like HypoThermosol® FRS and CryoStor® Freeze Media. Its customers include academic research institutions and biopharma manufacturers using these tools for basic and applied research.
INSP
Inspire Medical Systems
$1,661.30 Mn
57.47
+0.45%
-34.94%
Inspire Medical Systems designs and manufactures the Inspire system, a neurostimulation medical device used to treat obstructive sleep apnea. The company generates its primary revenue from selling this therapeutic implant to hospitals and ambulatory surgery centers.
TNDM
Tandem Diabetes Care
$1,650.18 Mn
23.73
+6.65%
+118.91%
Tandem Diabetes Care designs and manufactures durable insulin pump systems, specifically the t:slim X2 and Mobi platforms, which are therapeutic medical devices used for insulin delivery.
OMCL
Omnicell
$1,640.70 Mn
35.97
-0.17%
+13.79%
Omnicell designs and manufactures therapeutic and surgical medical devices, specifically automated dispensing cabinets and robotic compounding systems used for medication administration. These hardware products are sold to hospitals, health systems, and pharmacies to improve safety and efficiency in medication management.
KMTS
Kestra Medical Technologies
$1,630.66 Mn
27.93
+0.40%
+73.59%
Kestra designs and manufactures the ASSURE WCD, a wearable cardioverter defibrillator used to treat patients at risk of sudden cardiac arrest. This is a therapeutic medical device that monitors heart rhythm and delivers defibrillation shocks.
NKTR
2nd
Nektar Therapeutics
$1,500.70 Mn
73.64
+1.33%
+168.47%
The company historically generated revenue from the sale of its proprietary polyethylene glycol (PEG) reagents, which are tools used in bioproduction and life-sciences research to enhance drug pharmacokinetics.
MRVI
Maravai Lifesciences Holdings
$1,489.94 Mn
5.74
+1.06%
+123.35%
Maravai sells complex nucleic acids, custom enzymes, and antibody-based solutions used for research and biopharmaceutical production. These products, including mRNA oligonucleotides and nucleoside triphosphates, are sold to biopharmaceutical companies, biotech firms, and academic research institutions as life-sciences research tools and bioprocessing supplies.
CNMD
Conmed
$1,476.00 Mn
49.28
-0.06%
-7.70%
CONMED designs and manufactures therapeutic and surgical medical devices, including powered resection instruments, the Hall surgical brand of battery operated power tools, and electrosurgical generators. These products are sold to hospitals and surgery centers for use in orthopedics, general surgery, and gastroenterology.
ATEC
Alphatec Holdings
$1,472.30 Mn
9.53
+0.85%
-39.91%
Alphatec designs and manufactures spinal implants, instruments, and neuromonitoring systems used for the surgical treatment of spine disorders. These products are sold to hospitals and ambulatory surgery centers for use in spinal fusion and decompression procedures.
AZTA
Azenta
$1,443.36 Mn
32.98
-1.79%
+8.42%
Azenta sells a broad portfolio of life sciences research tools, including automated storage systems, cryogenic systems, and consumables like racks, tubes, and plates. These products are sold to pharmaceutical, biotechnology, and academic research institutions for sample exploration and management.
AORT
Artivion
$1,409.05 Mn
28.90
+2.01%
-32.56%
Artivion designs and manufactures therapeutic and surgical medical devices, specifically aortic stent grafts (e.g., E-vita Open NEO), mechanical heart valves (On-X), and surgical sealants (BioGlue). These products are sold to hospitals and healthcare facilities for use by surgeons in cardiac and vascular procedures.
IART
Integra Lifesciences Holdings
$1,364.91 Mn
17.55
-0.62%
+24.91%
Integra designs and manufactures therapeutic and surgical medical devices, including neurosurgical instruments, ICP monitoring systems, and cranial stabilization devices. These products are sold to hospitals and surgery centers for use in neurosurgery and neurocritical care.
DRTS
Alpha Tau Medical
$1,316.67 Mn
14.26
+0.78%
+337.42%
Alpha Tau Medical designs and manufactures the Alpha DaRT® technology, which consists of radioactive sources and specialized applicators used as localized radiation therapy for solid tumors. These products are therapeutic medical devices sold to oncology centers and hospitals for the treatment of cancers such as pancreatic adenocarcinoma and glioblastoma multiforme.
THRM
2nd
Gentherm
$1,293.92 Mn
42.14
-2.77%
+20.23%
The company's Medical segment designs and manufactures patient temperature management systems for hyperthermia and hypothermia therapy used in intensive care and surgical procedures.
MNKD
2nd
Mannkind
$1,261.34 Mn
4.07
+4.36%
+6.82%
The company designs and manufactures therapeutic medical devices, including a wearable insulin delivery device and the Furoscix subcutaneous furosemide infusor.
STAA
Staar Surgical
$1,235.03 Mn
24.64
+2.28%
-11.97%
Staar Surgical designs and manufactures implantable lenses for the eye, specifically the Implantable Collamer Lens (ICL) and associated delivery systems. These are therapeutic surgical medical devices used by ophthalmic surgeons to treat myopia, hyperopia, and astigmatism.
PRCT
PROCEPT BioRobotics
$1,220.51 Mn
21.32
+1.09%
-47.63%
PROCEPT BioRobotics designs and manufactures the AquaBeam and HYDROS Robotic Systems, which are image-guided robotic platforms used for the surgical treatment of benign prostatic hyperplasia. These are therapeutic and surgical medical devices sold to hospitals and ambulatory surgery centers.
NNNN
Anbio Biotechnology
$1,201.49 Mn
8.35
-1.53%
-83.84%
Anbio Biotechnology designs and sells in vitro diagnostic kits and instruments, including real-time PCR and chemiluminescence immunoassay products. Its revenue is derived from the sale of these diagnostic machines and the associated assays to hospitals, clinics, and laboratories.
BVS
Bioventus
$1,201.18 Mn
14.30
+3.03%
+99.16%
Bioventus designs and manufactures therapeutic and surgical medical devices, including peripheral nerve stimulation devices (StimRouter, Talismann), ultrasonic surgical platforms (neXus BoneScalpel), and ultrasound bone stimulation systems (EXOGEN). These products are sold to physicians, hospitals, and ambulatory surgical centers for use in orthopedic and neurosurgical procedures.
AVNS
Avanos Medical
$1,166.36 Mn
24.99
+0.04%
+110.35%
Avanos Medical designs and manufactures therapeutic and surgical medical devices, including ON-Q and ambIT surgical pain pumps, Game Ready cold and compression therapy systems, and COOLIEF radiofrequency ablation products. These products are sold to hospitals and ambulatory care centers for clinical use in pain management and recovery.
IRMD
Iradimed
$1,119.48 Mn
87.55
-0.53%
+24.88%
Iradimed designs and manufactures therapeutic and surgical medical devices, specifically MRI compatible infusion pumps, patient vital signs monitors, and ferromagnetic detection devices. These products are sold to hospitals and acute care facilities to enable safe MRI procedures for critically ill patients.
PCRX
2nd
Pacira BioSciences
$955.74 Mn
24.00
+3.27%
-3.58%
The company sells iovera°, a handheld cryogenic device used to deliver controlled cold to nerves for drug-free pain relief, which is a therapeutic medical device.
INMD
InMode
$949.75 Mn
14.99
-0.20%
+4.75%
InMode designs and manufactures energy-based minimally invasive surgical medical treatment solutions, such as the BodyTite and Morpheus8 platforms, which are used for face and body contouring. These products are therapeutic and surgical medical devices sold to plastic surgeons, dermatologists, and OB/GYNs.
AVR
Anteris Technologies Global
$933.20 Mn
9.58
+1.70%
+152.11%
Anteris Technologies Global designs and manufactures therapeutic medical devices for cardiac care, specifically the DurAVR® THV System and the ComASUR® Delivery System for treating aortic stenosis. These are surgical implants and delivery tools used in transcatheter aortic valve replacement (TAVR) procedures.
CBLL
Ceribell
$925.38 Mn
24.21
-0.78%
+98.77%
Ceribell sells the Ceribell System, which includes the Clarity recorder device and AI-powered algorithms for the rapid diagnosis and continuous monitoring of seizures and delirium. These are clinical diagnostic tools sold to hospitals for point-of-care EEG testing, fitting the description of diagnostic equipment and assays.
QDEL
QuidelOrtho
$917.27 Mn
13.43
-7.89%
-47.99%
QuidelOrtho manufactures and sells clinical diagnostic equipment and tests, including the VITROS platform for clinical chemistry and the ORTHO VISION platform for immunohematology. Its revenue model is based on the sale of instruments and a recurring stream of assays, reagents, and consumables.
AHG
2nd
Akso Health
$880.07 Mn
1.03
-14.88%
-41.48%
The company engages in the bulk purchase and resale of medical devices, specifically citing the sale of Class III defibrillators and Class II anesthesia laryngoscopes to hospitals and clinics.
SGP
2nd
SpyGlass Pharma
$864.25 Mn
25.84
+0.23%
—
The company's lead product, the BIM IOL System, is a medical device that combines a drug pad with an intraocular lens (IOL) for implantation during cataract surgery. This constitutes the design and manufacture of a therapeutic surgical implant.
BBNX
Beta Bionics
$855.55 Mn
19.02
+8.31%
+10.20%
Beta Bionics designs and manufactures the iLet Bionic Pancreas, which is a therapeutic medical device used for insulin delivery in patients with diabetes. The company generates revenue from the sale of this device to individual patients and healthcare providers.
SIBN
Si-Bone
$855.50 Mn
19.14
+2.41%
+23.17%
SI-BONE designs and manufactures titanium implants and associated instruments used to stabilize bone and promote fusion in the sacroiliac joint. These are therapeutic and surgical medical devices sold to hospitals, ambulatory surgery centers, and physicians.
AHCO
2nd
AdaptHealth
$793.30 Mn
5.82
+0.17%
-37.95%
A significant portion of revenue (approximately 63%) is derived from the sale of medical supplies and consumables, such as PAP masks, continuous glucose monitors, wound care products, and incontinence supplies.
VREX
Varex Imaging
$778.05 Mn
18.46
+0.00%
+67.36%
Varex designs and manufactures X-ray tubes, flat panel and photon counting detectors, and image processing software used in computed tomography, mammography, and fluoroscopy. These products are sold to OEMs and end-users for clinical diagnostic radiology modalities.
CYRX
2nd
Cryoport
$764.29 Mn
15.09
-1.50%
+71.67%
Cryoport provides bioprocessing and research-related tools through its IntegriCell cryopreservation services and BioStorage solutions used for preclinical and early-stage clinical materials.
SSII
SS Innovations International
$742.63 Mn
3.71
-1.33%
-43.36%
The company designs, manufactures, and markets the SSi Mantra Surgical Robotic System, which is used for various surgical procedures including urology and cardiac surgeries. Its revenue is derived from the sale of these surgical robots and related instruments.
KIDS
Orthopediatrics
$665.80 Mn
25.50
+3.24%
+32.81%
OrthoPediatrics designs and manufactures therapeutic and surgical medical devices, specifically orthopedic implants, instruments, and robotic insertion tools for pediatric patients. Its revenue is primarily generated from the sale of trauma plating systems, flexible intramedullary nails, and spinal implants.
ANGO
Angiodynamics
$659.70 Mn
15.82
+0.96%
+80.18%
AngioDynamics designs and manufactures therapeutic and surgical medical devices, including the Auryon Atherectomy System, NanoKnife ablation platforms, and VenaCure EVLT laser systems. These products are sold to hospitals and clinics for treating cardiovascular disease and cancer.
CTKB
Cytek Biosciences
$607.02 Mn
4.67
-1.48%
+15.02%
Cytek Biosciences develops and sells flow cytometry instruments, such as the Aurora and Northern Lights systems, and reagents like cFluor and Tonbo for high-dimensional single cell analysis. Its primary customers are pharmaceutical companies, biopharma firms, and academic research centers using these tools for drug discovery and research in oncology and immunology.
MLAB
Mesa Laboratories
$604.01 Mn
107.94
+0.28%
+57.81%
Mesa Laboratories designs and manufactures life sciences tools, including the MassARRAY system for genomic testing and Gyrolab systems for protein analysis and peptide synthesis. These products, along with their associated chips, panels, and reagents, are sold to biopharma R&D teams, academic laboratories, and clinical research labs.
BRSYF
Brainsway
$592.58 Mn
15.13
+0.00%
+175.59%
BrainsWay designs and manufactures the Deep Transcranial Magnetic Stimulation (Deep TMS) system, which is a therapeutic medical device used to treat major depressive disorder and OCD. Revenue is generated from the sale, leasing, and servicing of these hardware systems to psychiatrists, hospitals, and clinics.
DCTH
Delcath Systems
$583.97 Mn
16.86
-1.11%
+58.31%
Delcath Systems designs and manufactures therapeutic medical devices, specifically the CHEMOSAT hepatic delivery system and the HEPZATO KIT drug/device combination, used for percutaneous hepatic perfusion procedures to treat liver cancers. These products are sold to hospitals and cancer centers for surgical/interventional use.
OABI
2nd
OmniAb
$569.93 Mn
3.92
+2.62%
+95.02%
Through its xPloration segment, the company sells instruments and related consumables used in antibody discovery and optimization workflows to external customers.
DDD
2nd
3D Systems
$569.88 Mn
3.43
-5.51%
+64.11%
The company provides surgical planning tools, implants, and instrumentation for hospitals and medical device companies through its Healthcare Solutions segment.
CERS
Cerus
$556.21 Mn
2.76
-7.07%
+120.80%
Cerus designs and manufactures the INTERCEPT Blood System, which includes the INTERCEPT Illuminator (an LED-based device) used to inactivate pathogens in blood components. These are therapeutic/treatment devices sold to blood centers and hospitals.
TCMD
Tactile Systems Technology
$541.42 Mn
23.85
-3.01%
+89.59%
The company designs and manufactures therapeutic medical devices, specifically pneumatic compression systems (Flexitouch Plus, Entre Plus, Nimbl) for lymphedema and the AffloVest wearable vest for airway clearance. These are treatment devices used for chronic vascular and respiratory conditions, fitting the definition of therapeutic medical devices.
NPCE
NeuroPace
$496.07 Mn
14.47
+1.33%
+71.85%
NeuroPace designs and manufactures the RNS System, a brain responsive neurostimulation device used to treat drug resistant epilepsy. The company generates revenue from the sale of the neurostimulator, cortical and depth leads, and related accessories to hospitals and epilepsy centers.
CLPT
ClearPoint Neuro
$463.04 Mn
15.18
-2.06%
+35.29%
ClearPoint Neuro designs and manufactures therapeutic and surgical medical devices, including the ClearPoint system for deep brain stimulation and the SmartFrame OR Stereotactic System. Its revenue is driven by the sale of reusable hardware and high-margin disposable components like cannulas and catheters used in neurosurgical procedures.
SENS
Senseonics Holdings
$459.39 Mn
8.69
+8.22%
-7.55%
Senseonics designs and manufactures the Eversense CGM system, which consists of an implantable sensor and a removable smart transmitter. These are therapeutic/monitoring medical devices used for diabetes management, fitting the description of medical devices.
SGHT
Sight Sciences
$449.77 Mn
8.22
-0.24%
+96.18%
Sight Sciences designs and manufactures therapeutic and surgical medical devices, specifically the OMNI Surgical System and SION Surgical Instrument for glaucoma and the TearCare system for dry eye disease. These products are sold to healthcare providers for use in minimally invasive surgical procedures.
SI
Shoulder Innovations
$440.60 Mn
21.16
+5.91%
+47.66%
Shoulder Innovations designs and manufactures therapeutic medical devices, specifically anatomic and total shoulder implant systems for arthroplasty. Its revenue is primarily generated from the sale of these orthopedic implants to hospitals and ambulatory surgery centers.
OFIX
Orthofix Medical
$416.26 Mn
10.22
+1.89%
-29.57%
Orthofix designs and manufactures therapeutic and surgical medical devices, specifically spinal implants (pedicle screw systems, interbody spacers) and limb reconstruction systems (TrueLok external fixation, Fitbone intramedullary lengthening). These products are sold to hospitals and ambulatory surgery centers for the treatment of musculoskeletal pathologies.
DNA
2nd
Ginkgo Bioworks Holdings
$415.40 Mn
6.52
-5.78%
-52.75%
The company sells standardized tools and data assets, such as RAC systems and Datapoints, which are used for life-sciences research and bioproduction.
CARL
Carlsmed
$405.12 Mn
14.88
+7.98%
+12.90%
Carlsmed designs and manufactures patient-specific interbody implants and single-use surgical instruments for lumbar and cervical spine fusion surgery. These products are therapeutic medical devices sold to hospitals and ambulatory surgical centers.
MTLS
2nd
Materialise
$393.81 Mn
6.69
-0.59%
+31.69%
Materialise designs and manufactures personalized medical devices, including 3D printed surgical guides and patient-specific implants, sold to healthcare providers and medtech companies.
MASS
2nd
908 Devices
$383.63 Mn
10.08
-1.08%
+60.77%
The company sells its handheld chemical analysis devices to life science researchers for laboratory and field work, providing tools for research and bioproduction analysis.
TKNO
Alpha Teknova
$365.58 Mn
6.81
-5.68%
+54.42%
Alpha Teknova manufactures and sells reagents, pre-poured media plates, and liquid microbial culture media used for life-sciences research and bioproduction. Its Lab Essentials segment, which contributes 76.6% of revenue, specifically provides RUO formulations for applications like next generation sequencing and spatial biology.
CATX
2nd
Perspective Therapeutics
$365.08 Mn
3.20
-0.62%
-13.28%
The company develops and sells companion imaging agents using the isotope Lead 203 for patient selection and dosimetry, which are clinical diagnostic tools used to identify suitable patients for therapy.
PACB
Pacific Biosciences Of California
$354.32 Mn
1.14
-5.79%
-14.29%
Pacific Biosciences designs and manufactures sequencing instruments such as the Revio, Vega, and Sequel platforms, as well as proprietary consumables like SMRT cells and reagent kits. These products are sold to academic, governmental, and commercial research institutions for life-sciences research and genomic analysis.
VMD
2nd
Viemed Healthcare
$347.36 Mn
9.12
+0.77%
+31.79%
The company generates significant revenue from the rental and sale of home medical equipment and consumables, including ventilators, BiPAP, CPAP devices, oxygen concentrators, and breast pumps.
ELMD
Electromed
$344.03 Mn
41.55
+4.06%
+111.02%
Electromed designs and manufactures the SmartVest System, a therapeutic medical device utilizing high frequency chest wall oscillation technology to help patients clear lung secretions. The company's revenue is primarily derived from the sale of these devices, including the SmartVest SQL and SmartVest Clearway models.
OBIO
Orchestra BioMed Holdings
$340.19 Mn
5.66
+19.92%
+115.21%
Orchestra BioMed designs and develops therapeutic medical devices, specifically the AVIM Therapy for hypertension and the Virtue Sirolimus AngioInfusion Balloon for artery disease. These products are cardiovascular and interventional devices intended for clinical use in patients.
TLSI
TriSalus Life Sciences
$331.94 Mn
5.40
+2.47%
+11.11%
TriSalus designs and manufactures the FDA-cleared TriNav Infusion System, a medical device used by interventional radiologists for embolization procedures. The company's primary revenue is generated from the sale of this therapeutic device and its variants, such as TriNav FLX and TriNav XP.
PRE
Prenetics Global
$329.46 Mn
19.40
+0.15%
+155.94%
Prenetics operates ACT Genomics, which provides FDA-cleared comprehensive genomic profiling tests for solid tumors to hospitals and physicians. This activity involves selling diagnostic tests and the associated genomic profiling services for clinical use in oncology.
SMTI
Sanara MedTech
$314.14 Mn
34.17
+0.50%
+8.20%
Sanara MedTech designs and markets therapeutic surgical products, specifically bone fusion products like BiFORM and ALLOCYTE Plus, and soft tissue repair grafts like TEXAGEN and FORTIFY TRG, which are used in orthopedic, spine, and trauma surgeries.
CV
CapsoVision
$307.70 Mn
6.15
-4.65%
+53.75%
CapsoVision manufactures and sells the CapsoCam capsule endoscopy system, which is a clinical diagnostic tool used to visualize and detect pathologies in the small bowel and colon. Revenue is generated from the sale of these diagnostic capsules and associated software platforms like CapsoCloud and CapsoView.
RCEL
AVITA Medical
$304.63 Mn
9.85
+24.68%
+77.48%
AVITA Medical designs and manufactures therapeutic medical devices for acute wound care, specifically the RECELL autologous cell harvesting device used for treating thermal burns and full-thickness skin defects. These are regulated surgical instruments sold to hospitals, burn centers, and trauma centers.
TTRX
2nd
Turn Therapeutics
$297.58 Mn
9.99
+0.81%
—
The company has a Medical Device Licensing segment that monetizes FDA-cleared therapeutic devices, such as antimicrobial gauze (K183681) and dermatitis management products (K171191), through licenses with partners like Medline.
TMCI
Treace Medical Concepts
$289.40 Mn
4.45
-1.11%
-36.79%
Treace Medical Concepts designs and manufactures therapeutic and surgical medical devices, specifically the Lapiplasty 3D Bunion Correction System and the Adductoplasty Midfoot Correction System. Its revenue is generated from the sale of these implants and surgical instruments to hospitals and surgical practitioners.
EMBC
Embecta
$288.96 Mn
5.10
-0.58%
-62.17%
Embecta designs and manufactures therapeutic medical devices for diabetes management, specifically pen needles and insulin syringes. These products are used for the administration of insulin and other diabetes medications, fitting the description of treatment devices.
ANIK
Anika Therapeutics
$288.67 Mn
21.57
+0.47%
+148.22%
Anika Therapeutics designs and manufactures therapeutic medical devices and biomaterials, such as the Integrity scaffold for rotator cuff and tendon repairs and Tactoset for bone substitute. These products are sold directly to hospitals, ambulatory surgery centers, and physicians for surgical use.
BCYC
2nd
Bicycle Therapeutics
$278.56 Mn
3.99
-0.25%
-47.08%
The company develops Bicycle imaging agents used to validate targets before therapeutic development, which falls under the category of diagnostic equipment and tests.
MYGN
2nd
Myriad Genetics
$274.37 Mn
2.87
-5.90%
-49.74%
The company develops and commercializes diagnostic assays and companion diagnostics, such as BRACAnalysis CDx and MyChoice CDx, which are sold as specific diagnostic products to laboratories and providers.
RXST
RxSight
$264.90 Mn
6.37
-1.70%
-24.97%
RxSight designs and manufactures therapeutic medical devices, specifically the Light Adjustable Lens (an intraocular implant) and the Light Delivery Device used for postoperative adjustments. The company generates revenue from the sale of these surgical devices to eye care providers, hospitals, and ambulatory surgical centers.
OSUR
Orasure Technologies
$263.97 Mn
3.75
-1.57%
+33.93%
The company's primary business is the development and manufacture of diagnostic products, including rapid point-of-care tests for HIV, hepatitis C, and COVID-19. It generates significant revenue from the sale of these diagnostic test kits and related instruments to hospitals, clinics, and public health organizations.
ACIU
2nd
AC Immune
$262.05 Mn
2.57
+1.58%
+19.53%
The company has a dedicated Diagnostics segment focused on developing positron emission tomography (PET) tracers, such as PI-2620 and ACI-12589, which are used as diagnostic imaging agents to detect protein aggregates in the brain.
LAB
Standard Biotools
$258.80 Mn
0.66
-2.94%
-48.03%
Standard BioTools develops and sells instrumentation, consumables, and reagents for proteomics and genomics research, specifically through its CyTOF, Hyperion, and Biomark platforms. Its customers are research institutions and biopharmaceutical companies, and the profile explicitly states its products are marketed for research use only and not for clinical diagnostics.
PROF
Profound Medical
$255.73 Mn
7.00
+6.87%
+47.37%
Profound Medical designs and manufactures therapeutic medical devices, specifically the TULSA PRO and Sonalleve systems, which are used for the ablation of prostate tissue and uterine fibroids. Revenue is generated from the sale of this capital equipment and related service contracts.
INFU
2nd
InfuSystem Holdings
$243.15 Mn
12.21
+0.58%
+28.12%
The company generates significant revenue from the sale and rental of disposable supply kits, chemotherapy infusion supplies, and wound care products, which are medical consumables.
ACU
Acme United
$241.80 Mn
63.07
+1.81%
+56.62%
Acme United designs, manufactures, and distributes first aid kits and medical supplies under brands like First Aid Only and PhysiciansCare. These products are consumables and disposables, which aligns with the Medical Supplies industry.
STIM
Neuronetics
$240.01 Mn
3.15
-3.67%
-11.02%
Neuronetics designs and manufactures the NeuroStar Advanced Therapy System, a transcranial magnetic stimulation (TMS) device used to treat major depressive disorder and OCD. The company generates significant revenue from the sale of this capital equipment and associated service and repair contracts.
RELL
2nd
Richardson Electronics
$239.30 Mn
19.01
-4.57%
+96.38%
The company manufactures, repairs, and distributes high-value replacement parts for diagnostic imaging, specifically CT and MRI tubes and RF amplifiers, sold to hospitals and medical centers.
ORGO
Organogenesis Holdings
$230.33 Mn
1.79
+4.07%
-60.92%
Organogenesis designs and manufactures therapeutic medical devices and regenerative medicine products, such as PuraForce reinforcement matrix for tendon and ligament repair and NuShield placental allografts used as surgical barriers. These products are sold to hospitals, ambulatory surgery centers, and physician offices for clinical treatment.
UTMD
Utah Medical Products
$229.18 Mn
72.00
+2.55%
+25.98%
The company designs and manufactures therapeutic and surgical medical devices, specifically fetal monitoring accessories, intrauterine pressure catheters, and vacuum assisted delivery systems. These products are sold directly to hospitals, labor and delivery suites, and neonatal intensive care units.
SEER
Seer
$223.97 Mn
2.02
-0.49%
-1.46%
Seer sells the Proteograph Product Suite, which consists of life-sciences research tools including the SP200 automation instrument and consumable assays (Proteograph ONE and DIRECT) used for deep proteomic analysis. These products are sold to academic institutions and biopharmaceutical companies for basic research and biomarker discovery.
PDEX
Pro Dex
$213.82 Mn
66.89
-0.39%
+51.68%
Pro-Dex designs and manufactures surgical drivers and shavers used in orthopedic, thoracic, and craniomaxillofacial markets. These are therapeutic and surgical medical devices sold to original equipment manufacturers (OEMs).
ZSQR
2nd
Z Squared
$204.05 Mn
3.85
-0.26%
-73.72%
The company is developing the CD38-Diagnostic program, a diagnostic tool intended for healthcare providers to identify patients who would benefit from specific monoclonal antibody therapies.
NNBR
2nd
Nn
$201.88 Mn
3.84
-6.57%
+67.69%
The company manufactures medical tools for orthopedics and surgical applications, which are sold as components and instruments for the medical market.
LUCD
2nd
Lucid Diagnostics
$188.85 Mn
0.99
+1.02%
-2.94%
The company sells specimen kits and related consumables, including the EsoCheck Esophageal Cell Collection Device, to healthcare providers who collect samples on site.
LFCR
2nd
Lifecore Biomedical
$162.17 Mn
4.38
-3.52%
-40.81%
The company manufactures and sells pharmaceutical grade non-animal sourced hyaluronic acid (HA) in bulk form as a raw material for customers' use in various medical applications.
WALD
2nd
Waldencast
$161.96 Mn
1.37
+0.74%
-23.89%
The company has entered the aesthetics market through the launch of hyaluronic acid injectable fillers under the Saypha brand, which are therapeutic/surgical medical devices.
HUMA
2nd
Humacyte
$161.12 Mn
0.58
+3.57%
-67.78%
The company's products, such as the Symvess vascular conduit, are used as surgical implants for extremity arterial injury and hemodialysis access, functioning as therapeutic medical devices.
FOCL
Edap Tms
$159.67 Mn
4.26
-2.29%
+187.84%
EDAP TMS designs and manufactures therapeutic medical devices, specifically the Focal One Robotic HIFU system used for treating prostate cancer and endometriosis. The company's primary revenue is generated from the sale of this capital equipment and related maintenance and service contracts.
RANI
2nd
Rani Therapeutics Holdings
$155.35 Mn
0.83
+3.75%
+50.91%
The company's core technology is the RaniPill, a proprietary drug-agnostic oral delivery capsule designed to enable the administration of large molecules. This device-based platform is the primary mechanism used to achieve bioavailability comparable to subcutaneous injection.
KRMD
KORU Medical Systems
$153.68 Mn
3.33
-0.89%
-20.90%
KORU Medical designs and manufactures therapeutic medical devices, specifically the FREEDOM Infusion System, which includes syringe drivers used for delivering immunoglobulin. These are mechanical treatment devices sold to specialty pharmacies and home infusion providers.
INGN
Inogen
$149.69 Mn
5.60
-1.93%
-25.83%
Inogen designs and manufactures therapeutic medical devices, specifically portable and stationary oxygen concentrators, airway clearance devices, and CPAP masks. These products are used to treat chronic respiratory conditions and are sold as medical-grade hardware.
QSI
Quantum-Si
$145.23 Mn
0.73
-1.35%
-33.03%
Quantum-Si sells the Platinum and Platinum Pro protein sequencers, as well as consumable kits (Library Preparation, Barcoding, and Sequencing Kits), which are tools and reagents used for life-sciences research in proteomics. Its customers include academic research institutions, biopharmaceutical companies, and industrial laboratories using the platform for biomarker discovery and vaccine development.
IMDX
Insight Molecular Diagnostics
$139.63 Mn
4.28
+0.23%
+60.30%
The company develops and commercializes test kits, such as the GraftAssureIQ and GraftAssureDx IVD, which allow hospitals and laboratories to perform molecular diagnostic testing in-house. Its revenue model is based on the sale of these diagnostic kits and the associated reagents used on digital PCR instruments.
CDXS
Codexis
$137.08 Mn
1.50
-5.66%
-50.00%
Codexis sells engineered enzymes and proteins as biocatalysts and provides the CodeEvolver technology platform for bioproduction. Its revenue is derived from the sale of these research and production tools to pharmaceutical and biotechnology firms.
HSDT
2nd
Solana
$136.59 Mn
1.78
+7.23%
-72.32%
The company develops, manufactures, and sells the Portable Neuromodulation Stimulator (PoNS), a non-implantable medical device used to treat gait and balance deficits in patients with neurological conditions.
MXCT
Maxcyte
$134.79 Mn
1.27
-3.79%
-9.29%
MaxCyte sells the ExPERT family of instruments, proprietary processing assemblies (PAs), and consumables like electroporation buffers used for cell engineering and bioproduction. These products are sold to biopharmaceutical companies, academic institutions, and government research organizations for life-sciences research and development.
STXS
Stereotaxis
$133.90 Mn
1.37
-2.14%
-50.72%
Stereotaxis designs and manufactures therapeutic robotic systems for the interventional laboratory, specifically the Genesis RMN and GenesisX RMN platforms used for cardiac ablation. These are regulated medical devices used to steer catheters and guidewires during surgical procedures.
APYX
Apyx Medical
$130.98 Mn
3.11
+1.63%
+45.33%
Apyx Medical designs and manufactures therapeutic and surgical medical devices, specifically the Helium Plasma Platform (Renuvion) and the AYON Body Contouring System. These products are sold to physicians, cosmetic surgery clinics, and surgical centers for use in skin tightening and fat removal procedures.
VANI
2nd
Vivani Medical
$129.64 Mn
1.45
+7.41%
+16.94%
Through its subsidiary Cortigent, Inc., the company develops neurostimulation systems aimed at helping patients recover critical body functions, which are therapeutic medical devices.
QTRX
Quanterix
$126.32 Mn
2.68
-8.22%
-45.86%
Quanterix primarily sells life-sciences research tools, including the Simoa and Spatial Biology instruments (HD-X, SR-X, SP-X, PhenoCycler), as well as the associated assay kits, consumables, and reagents used by academic research labs and biopharmaceutical firms.
PAVM
PAVmed
$118.42 Mn
5.06
-4.89%
-60.87%
PAVmed's Lucid Diagnostics subsidiary sells the EsoGuard esophageal DNA test and the EsoCheck cell collection device to healthcare providers for the early detection of cancer. Revenue is generated from the sale of these diagnostic products and services, reimbursed by insurers and government programs.
GUTS
Fractyl Health
$114.23 Mn
0.72
+9.09%
-28.71%
The company's lead product candidate, Revita, is a balloon catheter used for hydrothermal ablation of the duodenal lining, which is a therapeutic medical device. The business model focuses on selling this device to physicians, hospitals, and ambulatory surgery centers for use in outpatient procedures.
NAUT
Nautilus Biotechnology
$108.14 Mn
0.85
-3.41%
+21.43%
Nautilus Biotechnology develops the Nautilus Voyager system, which is a life-sciences research tool for single molecule protein analysis. The company targets academic, biopharmaceutical, and research institutions for drug discovery and basic biology, selling instruments and recurring consumables like flow cells and reagent kits.
VATE
2nd
Innovate
$104.50 Mn
7.66
+1.32%
+72.52%
The Life Sciences segment commercializes medical and aesthetic technologies, specifically through R2 Technologies' Glacial Rx system and Genovel Orthopedics' knee osteoarthritis treatments.
LNSR
Lensar
$100.59 Mn
8.19
+1.24%
-35.76%
Lensar designs and manufactures therapeutic surgical medical devices, specifically the LENSAR Laser System and ALLY Robotic Cataract Laser System for cataract treatment. These products are sold to hospitals, ambulatory surgery centers, and physician practices for use in ophthalmic surgery.
KBLB
2nd
Kraig Biocraft Laboratories
$100.38 Mn
0.09
+0.00%
+12.50%
The company specifically targets the medical implant market, selling its biocompatible recombinant silk fibers to medical device manufacturers for use in surgical implants.
MBOT
Microbot Medical
$98.72 Mn
1.47
-2.65%
-52.27%
Microbot Medical designs and manufactures the LIBERTY Endovascular Robotic Surgical System, which is a robotic device used for minimally invasive endovascular procedures. The company sells this therapeutic robotic platform and associated components to hospitals and interventional radiology centers.
INO
2nd
Inovio Pharmaceuticals
$97.94 Mn
1.20
+4.35%
-36.84%
The company designs and sells a broad product line of CELLECTRA electroporation delivery devices used to enable in vivo protein production for its medicines.
BMGL
2nd
Basel Medical
$97.69 Mn
5.20
+0.19%
+148.80%
The company earns income from the sale of prescribed orthopedic devices to its patients, which constitutes a distinct product-based revenue stream alongside its service fees.
SERA
2nd
Sera Prognostics
$97.42 Mn
1.93
-1.03%
-18.91%
The company develops and sells the PreTRM test and maintains a pipeline of biomarker candidates for conditions such as preeclampsia and gestational diabetes, which constitutes the sale of a diagnostic test product.
RFL
2nd
Rafael Holdings
$95.76 Mn
1.87
+0.00%
+20.65%
The company owns Rafael Medical Devices, which designs and sells the VECTR System and related orthopedic instruments for minimally invasive ligament and fascia release procedures.
LUNG
Pulmonx
$94.18 Mn
2.26
+1.35%
+41.25%
Pulmonx designs and manufactures therapeutic medical devices, specifically the Zephyr Valve and associated delivery catheters used for lung volume reduction in emphysema patients. These are surgical/interventional implants sold to hospitals and healthcare providers.
ECOR
electroCore
$92.45 Mn
10.27
+0.20%
+91.60%
electroCore designs and manufactures prescription medical devices, specifically the gammaCore handheld vagus nerve stimulation device and the Quell Fibromyalgia wearable neuromodulation device. These products are FDA-cleared for treating primary headache and fibromyalgia symptoms.
NYXH
Nyxoah
$91.22 Mn
1.60
+0.00%
-75.65%
Nyxoah designs and manufactures the Genio system, which is an implantable hypoglossal neurostimulator used for the surgical treatment of Obstructive Sleep Apnea. The company generates revenue from the sale of these therapeutic medical devices to hospitals and sleep centers.
ICCC
2nd
Immucell
$88.64 Mn
9.76
+0.62%
+59.74%
The company sells the California Mastitis Test, which is used for the on-farm detection of udder inflammation, fitting the description of clinical diagnostic tests and assays.
BNR
2nd
Burning Rock Biotech
$87.87 Mn
10.00
+9.89%
-1.67%
Through its In-Hospital Model, the company sells turnkey laboratory solutions and recurring reagent kits to hospitals, which constitutes the sale of diagnostic equipment and the consumables required to run them.
ACH
2nd
Accendra Health
$86.13 Mn
1.12
+4.67%
-79.45%
The company generates significant revenue from the sale of medical supplies and consumables, specifically citing ostomy pouches, advanced wound dressings, and urinary catheters.
CHRN
ChronoScale Holdings
$83.84 Mn
23.53
+6.04%
+626.23%
The company designs and manufactures wearable robotic exoskeletons for clinical and personal use, such as the EksoNR and Ekso Indego Therapy units. These are therapeutic and surgical medical devices used for physical rehabilitation and mobility for individuals with physical disabilities.
HYPR
Hyperfine
$81.89 Mn
0.90
+0.00%
-30.23%
Hyperfine manufactures and sells the Swoop® system, which is a portable ultra low field magnetic resonance brain imaging scanner used for clinical diagnosis. The company generates revenue from the sale of these diagnostic instruments and recurring software service and support agreements.
OM
Outset Medical
$78.57 Mn
4.18
-7.32%
-69.42%
Outset Medical designs and manufactures the Tablo Hemodialysis System, which is a therapeutic medical device used for dialysis. The company generates revenue from the sale and lease of these consoles to hospitals, clinics, and home care programs.
SKIN
SkinHealth Systems
$78.06 Mn
0.60
+0.00%
-72.60%
The company designs and manufactures therapeutic medical devices for skin health, specifically the Syndeo, Elite Tower, and Allegro devices, as well as SkinStylus microneedling systems. These are sold as durable capital equipment to professional medical providers, dermatologists, and plastic surgeons.
NRXS
Neuraxis
$78.05 Mn
6.26
+0.32%
+152.42%
Neuraxis designs and manufactures therapeutic medical devices, specifically the IB-Stim stimulator for abdominal pain and the RED rectal expulsion device. These are cleared medical devices sold to healthcare providers for clinical use in treating gastrointestinal disorders.
COCH
Envoy Medical
$76.99 Mn
0.74
+0.00%
-45.19%
Envoy Medical designs and manufactures implantable hearing devices, specifically the Esteem FI AMEI active middle ear implant and the investigational Acclaim CI cochlear implant. These are therapeutic surgical implants sold to surgeons, audiologists, and clinics.
RTGN
RetinalGenix Technologies
$75.02 Mn
4.00
+0.00%
+12.99%
The company's core revenue strategy centers on the sale of DNA/GPS laboratory-developed genetic testing kits and the development of the RetinalCam imaging device for screening and monitoring eye health. These products are clinical diagnostic tools sold to patients and healthcare providers to identify biomarkers and disease states.
ALUR
Allurion Technologies
$74.67 Mn
4.98
+5.51%
-88.78%
Allurion designs and manufactures the Allurion Smart Capsule, a swallowable intragastric balloon used for weight loss. This is a therapeutic medical device sold to healthcare providers such as clinics and hospitals.
TANAF
Tian'an Technology
$73.74 Mn
1.62
+29.60%
-88.26%
The company's primary revenue driver is the sale of graphene-based far infrared therapy devices, including energy rooms, heating blankets, and moxibustion instruments, which are designed for therapeutic benefits like pain relief and muscle relaxation.
CVRX
CVRx
$73.26 Mn
2.75
+0.00%
-59.97%
CVRx designs and manufactures the Barostim system, which consists of an implantable pulse generator and stimulation lead used to treat heart failure. These are therapeutic medical devices sold to hospitals and cardiac centers.
SKYA
SkyAI
$71.37 Mn
0.99
-1.00%
-80.43%
The company generates revenue primarily through the sale of syringe products and related drug delivery systems. These are described as medical supplies and consumables sold to hospitals, clinics, and healthcare providers.
RPID
Rapid Micro Biosystems
$70.93 Mn
1.56
+0.65%
-41.13%
Rapid Micro Biosystems sells the Growth Direct platform, which is an automated microbial testing system using high-speed imaging and vision algorithms for clinical/quality control diagnosis. Revenue is generated from the sale of these diagnostic instruments and the proprietary consumables and reagents required to run them.
JRSH
2nd
Jerash Holdings (US)
$68.33 Mn
5.38
-4.61%
+59.64%
The company operates a dedicated unit, Jerash The First Medical Supplies Manufacturing Company Limited, which is specifically focused on the manufacturing and trade of personal protective equipment (PPE) products.
DRIO
2nd
DarioHealth
$67.09 Mn
7.18
-2.45%
-20.19%
DarioHealth sells FDA-cleared hardware devices that generate continuous physiological data as part of its integrated solution. These are medical-grade regulated wearables/devices used for clinical monitoring of chronic conditions.
MYO
Myomo
$64.57 Mn
1.68
+7.01%
+50.00%
Myomo designs and manufactures the MyoPro product line, which consists of myoelectric-controlled upper limb braces or orthoses. These are therapeutic medical devices used to support paralyzed arms and improve functional activities of daily living.
CUPR
Cuprina Holdings (Cayman)
$63.71 Mn
2.97
+1.71%
-71.44%
The company's primary revenue driver is the MEDIFLY line, which consists of sterile blowfly larvae bio dressings used in hospitals and clinics for chronic wound management. This product, along with its pipeline of collagen dressings and iodine-based topical antiseptics, falls under medical supplies and consumables.
NNOX
Nano-X Imaging
$61.94 Mn
0.89
-4.30%
-79.11%
The company develops and sells the Nanox. ARC hardware system, which is a digital X-ray source used for medical imaging. Its primary business is the sale of this diagnostic equipment to hospitals, clinics, and imaging centers.
JANL
2nd
Janel
$61.67 Mn
51.98
+3.96%
+29.95%
The Life Sciences segment manufactures and distributes antibodies and research and diagnostic reagents for academic, non-profit, and commercial customers, which are tools used for life-sciences research.
MDNC
Medinotec
$58.78 Mn
5.00
+0.00%
+0.00%
Medinotec designs and manufactures therapeutic and surgical medical devices, specifically tracheal dilation devices and coronary catheters. Its revenue is derived from the sale of products such as the Trachealator and the Cape Cross PTCA catheter to hospitals and clinics.
IMMP
2nd
Immutep
$58.42 Mn
0.40
+2.56%
-77.53%
The company generates income through its subsidiary, Immutep S A S, which manufactures and distributes research reagents to scientists via third-party distributors such as Adipogen and Enzo.
NSPR
InspireMD
$56.61 Mn
0.88
+0.00%
-64.66%
InspireMD designs and manufactures therapeutic medical devices, specifically the CGuard and CGuard Prime carotid embolic prevention systems. These products are self-expandable nitinol stents used in surgical procedures to treat carotid artery disease.
RNXT
RenovoRx
$52.79 Mn
1.17
-2.50%
+24.47%
RenovoRx generates its current revenue from the sale of the RenovoCath device, a FDA-cleared local drug delivery system used for temporary vessel occlusion and chemotherapeutic drug infusion. Its customers are U.S. cancer centers and hospitals that purchase these therapeutic medical devices.
MDAI
Spectral AI
$51.82 Mn
1.61
-1.83%
-24.06%
Spectral AI develops the DeepView System, which is a clinical diagnostic platform combining multispectral imaging and AI algorithms to predict wound healing. The company sells both the imaging device (hardware) and the associated diagnostic software to hospitals and burn centers.
ALPS
Alps
$49.92 Mn
0.30
-6.25%
—
Alps Life Sciences Inc is engaged in the research, development, and commercialization of life sciences products and services, serving research institutions, laboratories, and biotechnology firms. This aligns with the provision of tools and reagents for life-sciences research and bioproduction.
NEPH
Nephros
$49.85 Mn
4.59
+6.25%
+6.74%
Nephros designs and manufactures FDA 510(k) cleared Class II medical devices, specifically microfilters and ultrafilters used in hospitals and dialysis centers to prevent waterborne pathogen transmission and ensure ultrapure dialysate quality.
SRTS
Sensus Healthcare
$49.39 Mn
3.00
+3.45%
-9.37%
Sensus Healthcare designs and manufactures therapeutic medical devices, specifically the SRT 100, SRT 100 plus, and SRT 100 Vision systems used for non-invasive treatment of skin cancer. These are radiation therapy systems sold to dermatology practices and radiation oncology departments.
XTNT
Xtant Medical Holdings
$47.61 Mn
0.34
+3.03%
-47.68%
Xtant Medical Holdings designs and manufactures therapeutic and surgical medical devices, specifically spinal implant fixation systems including cervical plating, thoracolumbar pedicle screw systems, and interbody spacers. These products are sold to hospitals and surgery centers for use by orthopedic spine surgeons and neurosurgeons.
PRPO
2nd
Precipio
$43.97 Mn
24.69
+3.31%
+72.66%
The company's Products Division commercializes proprietary diagnostic assays and kits, such as HemeScreen and IV-Cell, which are sold as products to external clinical laboratories.
SNWV
SANUWAVE Health
$43.27 Mn
5.03
+1.41%
-86.89%
Sanuwave designs and manufactures the UltraMIST system, a noninvasive ultrasound device used to treat acute and chronic wounds. This is a therapeutic medical device used by clinicians to stimulate tissue repair and regeneration.
SGMOQ
2nd
Sangamo Therapeutics
$42.03 Mn
0.15
-6.25%
-74.58%
The company explicitly expects to receive additional income from licensing its technology to other industries, specifically mentioning research reagents.
HYPD
2nd
Hyperion Defi
$41.31 Mn
2.70
-4.93%
-63.81%
The company is developing the Optejet ophthalmic liquid delivery device, which is a therapeutic medical device designed to deliver topical ocular medications via a micro droplet spray to patients and clinics.
QTI
Qt Imaging Holdings
$40.07 Mn
2.91
+7.78%
-90.85%
The company designs and manufactures the QT Breast Scanner, as well as developing scanners for orthopedic and infant imaging. These are therapeutic and surgical medical devices used by healthcare providers for diagnostic imaging.
MLSS
Milestone Scientific
$39.42 Mn
0.49
+0.00%
-22.35%
The company's primary revenue and operational focus is on its Dental Products segment, specifically the CompuDent and STA Single Tooth Anesthesia Systems sold to dental practitioners and groups. This aligns with the H-09 category for companies that make dental products and equipment.
ELUT
Elutia
$39.35 Mn
0.89
-9.18%
-55.94%
Elutia designs and manufactures therapeutic medical devices, specifically biomatrix products for surgical reconstruction. Its cardiovascular products, such as ProxiCor and VasCure, have received 510(k) clearance as medical devices for cardiac tissue repair and vascular reconstruction.
SY
2nd
So-Young International
$37.15 Mn
2.21
+0.00%
-38.87%
Through its subsidiary Wuhan Miracle, the company designs and manufactures laser and photonic devices and surgical lasers sold to third-party clinics and hospitals.
ARAY
Accuray
$36.87 Mn
0.31
-6.06%
-80.86%
Accuray designs and manufactures therapeutic medical devices, specifically the CyberKnife robotic system and the Radixact and Helix radiation delivery platforms. These systems are used for radiation treatments in oncology, neurology, and endocrine disorders, fitting the description of therapeutic and surgical medical devices.
TELA
TELA Bio
$36.75 Mn
0.64
-1.54%
-62.35%
TELA Bio designs and manufactures therapeutic medical devices for soft tissue reconstruction, specifically the OviTex and OviTex PRS reinforced tissue matrices used in hernia repair and plastic surgery. These products are implanted during surgical procedures to reinforce soft tissue, fitting the description of surgical medical devices.
POCI
Precision Optics Corporation
$33.83 Mn
4.34
+3.83%
-6.26%
The company designs and manufactures therapeutic medical devices, specifically endoscopes, endocouplers, and digital imaging endoscopes used in minimally invasive surgical procedures. These products are sold to established and emerging medical device companies.
BDMD
Baird Medical Investment Holdings
$33.52 Mn
1.09
-4.39%
-48.83%
The company's primary revenue is derived from the sale of proprietary microwave ablation medical devices, specifically therapeutic apparatus and needles used for treating thyroid nodules and breast lumps. These are therapeutic and surgical medical devices sold to hospitals in China.
UG
2nd
United Guardian
$32.48 Mn
7.07
-1.12%
-9.48%
The company produces medical lubricants sold directly to manufacturers of medical devices, such as catheter and surgical instrument producers, which accounts for 20% of total sales.
HBIO
Harvard Bioscience
$31.73 Mn
6.97
+7.23%
+39.40%
Harvard Bioscience develops and manufactures instruments, reagents, and consumables for life-sciences research, such as spectrophotometers, amino acid analyzers, and electroporation systems. Its products are sold to academic institutions and pharmaceutical companies for use in early discovery and bioproduction.
CCEL
2nd
Cryo Cell International
$31.61 Mn
3.92
-1.75%
-7.33%
The company manufactures and sells the PrepaCyte® CB Processing System, which is described as a 510(k) cleared Class II medical device used to process stem cells.
RMTI
Rockwell Medical
$29.87 Mn
7.52
+0.40%
+616.19%
Rockwell Medical manufactures and sells hemodialysis concentrates (liquid and dry acid and bicarbonate) and ancillary supplies like cleaning agents and salts. These are consumables used in dialysis machines, which fits the description of medical supplies and consumables.
DYAI
2nd
Dyadic International
$27.69 Mn
0.76
-2.56%
-5.00%
The company sells life science reagents such as albumin, transferrin, and DNase I, and serves life science researchers and diagnostic manufacturers.
CPHI
2nd
China Pharma Holdings
$27.39 Mn
1.07
-2.73%
-27.21%
The company manufactures and sells medical supplies and consumables, specifically medical masks and related personal protective equipment.
RDGL
Vivos
$27.33 Mn
0.06
+0.00%
-25.00%
Vivos designs and manufactures the RadioGel and IsoPet devices, which are described as yttrium 90 based precision radionuclide therapy devices for treating solid tumors. These are therapeutic medical devices used by physicians and veterinarians to deliver localized beta radiation.
BEAT
HeartBeam
$27.05 Mn
0.48
-4.00%
-59.66%
HeartBeam designs and manufactures the HeartBeam System, which is an FDA-cleared cable-free ambulatory 12L ECG recording device used for arrhythmia assessment. This is a therapeutic and surgical medical device used for clinical diagnostics outside of healthcare facilities.
QTEX
QTREX Quantum
$26.66 Mn
0.90
-4.26%
-27.71%
The company designs and manufactures therapeutic medical devices for life support, specifically the INSPIRA ART100 cardiopulmonary bypass system and the VORTX orbiting blood oxygenation device. These are surgical/treatment devices used in hospitals to replace invasive mechanical ventilation.
VRXA
2nd
Veraxa Biotech Holding AG
$25.91 Mn
1.79
-3.76%
-82.82%
The company operates the Hitmaster Microfluidics Platform, which provides high-throughput antibody discovery, single-cell analysis, and precision sorting of biological particles for research and diagnostic applications.
QUCY
Quantum Cyber
$25.53 Mn
1.43
-2.72%
-20.56%
Mainz Biomed manufactures and sells the ColoAlert in vitro diagnostic test, which combines a fecal immunochemical test and PCR analysis, to clinical laboratories and hospitals. The company's revenue is generated through the sale of these diagnostic tests and associated consumables rather than performing the tests itself.
GIPL
2nd
Global Innovative Platforms
$24.34 Mn
0.50
+0.00%
+316.67%
The company manufactures clinical diagnostic equipment, specifically gas chromatographs and the FROG unit, and sells the associated consumables and reagents required to run these tests.
NMAD
2nd
Nomad Power Solutions
$24.07 Mn
4.22
+8.21%
+10.47%
Through its majority ownership of Liora Technologies Europe Ltd., the company is developing electronically controlled proton therapy systems for treating tumors, which are therapeutic medical devices.
CRVW
CareView Communications
$23.36 Mn
0.04
+0.00%
+100.00%
CareView designs and manufactures therapeutic and surgical medical devices, specifically high-definition cameras, two-way audio systems, and LCD displays used for patient video monitoring. These products are sold as hardware components including the CareView Controller and SitterView Monitor to hospitals and healthcare facilities.
CTSO
Cytosorbents
$22.62 Mn
0.36
-5.26%
-67.27%
CytoSorbents designs and manufactures therapeutic medical devices, specifically blood purification cartridges like CytoSorb and the PuriFi hemoperfusion pump, used in intensive care and cardiac surgery.
AIFF
Firefly Neuroscience
$22.43 Mn
1.09
-3.54%
-60.65%
Firefly Neuroscience manufactures and sells the FDA 510k cleared Evoke System, which is a diagnostic platform used to capture and analyze EEG and ERP assessments. The company generates revenue from subscriptions that provide clinics with this diagnostic equipment and the associated analytics and reporting platform.
RVP
Retractable Technologies
$21.55 Mn
0.72
+2.86%
-10.04%
Retractable Technologies manufactures and markets medical supplies and consumables, specifically the VanishPoint, Patient Safe, and EasyPoint lines of retractable syringes and needles. These products are disposable injection devices sold to hospitals, clinics, and long-term care facilities.
ALLR
2nd
Allarity Therapeutics
$21.48 Mn
1.35
+0.75%
+48.35%
The company develops and sells the Drug Response Predictor (DRP®) platform, which creates cancer drug-specific companion diagnostics to identify patients likely to benefit from therapy. This platform has supported FDA Investigational Device Exemption (IDE) applications for stenoparib and Liposomal CisPlatin.
CELU
2nd
Celularity
$21.34 Mn
0.74
+5.71%
-82.17%
The company generates significant revenue from the sale of commercial biomaterial products and allografts, such as Biovance and Interfyl, used by hospitals and wound-care providers for soft-tissue repair.
ZJYL
Jin Medical International
$21.03 Mn
3.08
-10.98%
-74.74%
Jin Medical International designs and manufactures therapeutic and surgical medical devices, specifically manual and electric wheelchairs and related components, which account for the majority of its revenue (78.4% in fiscal 2025). These products are sold to dealers who distribute them to hospitals, rehabilitation centers, and individual consumers.
MOVE
2nd
Corvex
$19.49 Mn
10.14
-0.20%
+123.35%
The company develops and sells the FDA-cleared Medical Ring, which is a regulated medical device used for pulse oximetry and remote patient monitoring.
AZIO
2nd
Azio Ai Holdings
$18.74 Mn
1.37
+0.00%
-31.84%
The company operates a medical supplies segment that generates revenue from the delivery of medical gowns to a related party and the federal government.
PLSM
Pulsenmore
$18.66 Mn
2.87
-0.69%
—
Pulsenmore designs and manufactures portable ultrasound devices, such as the Pulsenmore ES and FC, which are used for diagnostic imaging of fetal heartbeats and ovarian follicles. The company generates revenue from the sale of these diagnostic machines and associated services to healthcare organizations like Clalit and Sheba Medical Center.
MODD
Modular Medical
$16.88 Mn
3.03
+27.85%
-85.59%
Modular Medical designs and manufactures therapeutic medical devices, specifically the MODD1 and Pivot insulin pumps for patients with diabetes. These are regulated wearable treatment devices intended for clinical use.
NMTC
Neuroone Medical Technologies
$16.36 Mn
1.88
+0.00%
-62.25%
NeuroOne designs and manufactures therapeutic and surgical medical devices, specifically the OneRF Brain Ablation System and OneRF TN Ablation System for lesion creation and trigeminal neuralgia treatment. These are surgical instruments used for ablation and stimulation in brain-related conditions.
IRIX
Iridex
$16.18 Mn
0.93
+5.68%
-20.51%
IRIDEX designs and manufactures therapeutic laser consoles and delivery devices used to treat glaucoma and retinal diseases. These are surgical medical devices sold to ophthalmologists, hospitals, and ambulatory surgical centers.
CYCN
2nd
Cyclerion Therapeutics
$15.22 Mn
4.12
+2.23%
+62.20%
The company's strategy for CYC 126 involves a 'closed loop monitoring system' and 'device technology' to individualize the dosing of anesthetic agents, indicating the development of a therapeutic medical device to accompany its pharmacological approach.
ADGM
Adagio Medical Holdings
$14.44 Mn
0.65
+0.00%
-49.61%
Adagio Medical Holdings designs and manufactures the vCLAS Cryoablation System, which consists of a catheter and console used for the surgical treatment of cardiac arrhythmias. The company's core business is the development of this therapeutic medical device for use in electrophysiology labs and hospitals.
ICU
SeaStar Medical Holding
$14.23 Mn
3.34
+2.77%
-59.76%
SeaStar Medical designs and manufactures the Selective Cytopheretic Device (SCD), specifically the QUELIMMUNE product, which is a therapeutic extracorporeal synthetic membrane cartridge used to treat critically ill patients. The company generates revenue from the sale of these medical devices to hospitals for use in intensive-care units.
ASTC
2nd
Astrotech
$13.95 Mn
7.93
-2.82%
+56.10%
Through BreathTech Corporation, the company develops the BreathTest 1000 for disease screening via volatile organic compound metabolites, collaborating with clinical entities like the Cleveland Clinic Foundation.
BNGO
Bionano Genomics
$13.90 Mn
1.18
-0.84%
-62.54%
Bionano Genomics sells optical genome mapping instruments like the Saphyr and Stratys systems, along with the consumables and reagents required to operate them. These products are sold to academic research institutions and biotechnology companies for life-sciences research and genomic analysis.
ALRTF
ALR Technologies SG
$12.91 Mn
0.02
+0.00%
+100.00%
The company sells the 'Diabetes Solution' and 'GluCurve Pet CGM' products, which are FDA-cleared diagnostic systems that collect and analyze blood glucose data to provide clinical insights. These products are sold as diagnostic equipment and tests to healthcare providers, hospitals, and veterinary clinics.
TOMZ
2nd
TOMI Environmental Solutions
$12.14 Mn
1.76
-1.12%
+93.41%
The company provides disinfection solutions specifically for the Hospital-Healthcare segment, targeting operating rooms and pharmacies to combat healthcare-associated infections, which falls under medical supplies and consumables.
ADVB
Advanced Biomed
$12.05 Mn
8.72
+5.95%
+3.81%
Advanced Biomed develops and sells medical testing equipment for cancer screening and diagnosis, specifically microfluidic biochips and devices like A+Pre and AC-1000. These products are sold to hospitals and clinical laboratories as diagnostic platforms and assays.
LFWD
Lifeward
$11.94 Mn
7.41
+1.37%
-3.39%
Lifeward designs and manufactures therapeutic medical devices, specifically the ReWalk exoskeleton suite, the ReStore exo suit, and the AlterG anti-gravity system. These products are used for physical rehabilitation and recovery for patients with spinal cord injuries and stroke.
EBRCZ
EBR Systems
$11.82 Mn
0.24
+0.00%
-56.36%
EBR Systems designs and manufactures the WiSE CRT System, which is an implantable cardiac pacing system used to correct heart rhythm conditions. The system consists of therapeutic and surgical medical devices including an implantable electrode, a subcutaneous transmitter, and a delivery catheter.
AMS
2nd
American Shared Hospital Services
$9.81 Mn
1.48
-4.52%
-40.80%
The company generates revenue from the sale and leasing of stereotactic radiosurgery and advanced radiation therapy equipment, such as Gamma Knife and proton therapy units, to hospitals and clinics.
UEEC
United Health Products
$9.79 Mn
0.04
+0.00%
-60.00%
The company manufactures and markets CelluSTAT, a patented hemostatic gauze used for superficial wound care. This product is a medical consumable/disposable supply sold to hospitals, clinics, and other point-of-care providers.
DROR
Dror Ortho-Design
$9.77 Mn
0.01
+0.00%
-50.00%
The company develops the ZSmile and Aerodentis systems, which are FDA-cleared medical devices specifically for correcting tooth alignment (malocclusion). Its primary customers are dental professionals, including orthodontists and general dentists, who prescribe these aligners to patients.
BRGX
Bioregenx
$9.72 Mn
0.01
+0.00%
+0.00%
The company develops and sells the GlycoCheck™ system, which is explicitly described as a Class I medical device sold to hospitals, academic research institutions, and wellness practitioners.
BBLGW
Bone Biologics
$9.68 Mn
8.24
-3.06%
-23.63%
Bone Biologics is a medical device company developing NB1, a combination product for spinal fusion and lumbar interbody fusion procedures. Its intended customers are spine surgeons, orthopedic surgeons, and hospitals.
COSM
2nd
Cosmos Health
$8.62 Mn
0.21
+5.00%
-75.29%
The company's business profile explicitly states that it produces medical devices as part of its diversified healthcare group.
MBAI
Check-Cap
$8.38 Mn
8.36
+4.24%
+1,166.67%
Check-Cap develops the C Scan system, which consists of an ingestible X-ray emitting capsule (C Scan Cap) and a receiver (C Scan Track) used for clinical diagnostic imaging of the colon. The company sells the diagnostic machine and the associated software (C Scan View) to gastroenterology clinics and hospitals rather than performing the tests itself.
SCND
Scientific Industries
$8.35 Mn
0.70
+7.69%
-15.66%
Scientific Industries designs and manufactures benchtop laboratory equipment and bioprocessing systems, such as biomass monitoring sensors and moisture analyzers, sold to universities and pharmaceutical companies for research. These products, including the DOTS brand platform and Torbal balances, are classic life-sciences research tools and bioprocessing supplies.
ADIL
2nd
Adial Pharmaceuticals
$8.23 Mn
5.45
+9.22%
-42.63%
The company develops and utilizes a companion diagnostic genetic test to identify patients likely to respond to its lead drug candidate, AD04.
SINT
Sintx Technologies
$7.86 Mn
1.62
-1.22%
-49.06%
SINTX designs and manufactures therapeutic medical devices, specifically interbody spinal fusion implants and foot and ankle osteotomy wedges. These products are sold directly to hospitals and surgical centers or through OEM partnerships.
TRIB
Trinity Biotech
$7.75 Mn
12.43
+11.28%
+691.72%
Trinity Biotech develops and manufactures clinical diagnostic equipment and tests, including rapid tests, enzyme linked immunosorbent assays, and molecular diagnostics platforms. It generates revenue from the sale of diagnostic kits, instruments, and reagents to hospitals and clinical laboratories.
NVNO
enVVeno Medical
$7.42 Mn
11.03
-6.53%
-93.69%
enVVeno Medical designs and manufactures implantable medical devices, specifically the surgical VenoValve and the transcatheter enVVe System, to treat chronic venous insufficiency. These products are described as Class III implantable devices intended for use by vascular surgeons and interventional radiologists.
NXL
Nexalin Technology
$7.26 Mn
0.33
-2.94%
-59.26%
Nexalin designs and manufactures neurostimulation medical devices, specifically the Gen-2 SYNC clinical device and the Gen-3 HALO patient headset, for treating mental health conditions. These are therapeutic medical devices used for brain stimulation, which fits the definition of H-06.
ICCM
IceCure Medical
$7.20 Mn
2.60
-7.80%
-90.28%
IceCure Medical designs and manufactures therapeutic medical devices, specifically the ProSense, IceSense3, and XSense cryoablation systems used to ablate tumors. These are surgical treatment devices sold to hospitals, ambulatory surgical centers, and private clinics.
PLRZ
Polyrizon
$7.05 Mn
10.36
-5.65%
+67.64%
Polyrizon develops innovative medical device hydrogels delivered as nasal sprays that form a physical shield containment barrier in the nasal cavity. This product is described as a medical device designed to block viruses and allergens from contacting epithelial tissue.
LNAI
2nd
Lunai Bioworks
$6.75 Mn
2.16
-4.00%
-88.33%
The Renovaro Cube segment sells diagnostic test kits and provides an AI-driven platform for early cancer detection and recurrence monitoring, targeting hospitals and research centers.
FEMY
Femasys
$6.64 Mn
2.20
+1.85%
-84.29%
Femasys designs and manufactures therapeutic and surgical medical devices for women's health, such as FemBloc for non-surgical permanent contraception and FemaSeed for intrauterine insemination. Its revenue is generated from the sale of these medical devices to healthcare providers like gynecologists and reproductive endocrinologists.
ACON
2nd
Aclarion
$6.40 Mn
2.60
-6.14%
-64.28%
The company provides the NOCISCAN MRS exam protocol and diagnostic technology used by imaging centers to perform clinical diagnostic tests for painful intervertebral discs. Its revenue is derived from payments from imaging centers and third-party payer reimbursements for these diagnostic exams.
STME
Stimcell Energetics
$6.34 Mn
0.30
+0.00%
+7.14%
Stimcell Energetics designs and manufactures the eBalance® Pro System for healthcare professionals and the eBalance® Home System for consumers, both of which are microcurrent electrical therapy devices. These products are described as Class II Medical Devices used for pain relief and managing health complications like insulin sensitivity and high blood pressure.
DQWS
2nd
DSwiss
$6.21 Mn
0.03
+0.00%
-57.14%
The company explicitly generates revenue from the sale of medical consumable supplies to its clients.
CDIO
Cardio Diagnostics Holdings
$5.65 Mn
1.91
-4.02%
-48.66%
The company develops and sells clinical diagnostic tests such as Epi+Gen CHD and PrecisionCHD, which are used for the early detection and risk assessment of cardiovascular diseases. These products are sold as diagnostic assays to healthcare providers and health systems.
NDRA
ENDRA Life Sciences
$5.60 Mn
4.51
+0.45%
-6.43%
ENDRA develops the Thermo-Acoustic Enhanced Ultrasound (TAEUS) platform, which is a clinical diagnostic tool used to measure liver fat as a biomarker for metabolic diseases. The company sells the diagnostic capability via direct product sales, subscriptions, and licensing to OEMs, positioning it as a point-of-care alternative to MRI scans.
HSCS
HeartSciences
$5.59 Mn
2.13
-3.62%
-43.20%
HeartSciences develops and sells the MyoVista wav ECG device and AI ECG algorithms specifically for the clinical diagnosis of cardiac dysfunction and heart conditions. The company's revenue model is based on the sale of these diagnostic instruments and the recurring fees for the AI-driven diagnostic analysis.
SNOA
Sonoma Pharmaceuticals
$5.00 Mn
1.30
-1.52%
-75.70%
Sonoma Pharmaceuticals manufactures medical supplies and consumables, specifically stabilized hypochlorous acid products for wound care, eye care, and dermatological conditions. These products are sold as office dispense items and consumables to hospitals, physicians, and clinics.
PMI
Picard Medical
$4.92 Mn
3.27
-8.40%
—
Picard Medical designs and manufactures the SynCardia Total Artificial Heart (TAH), which is a fully implantable therapeutic medical device used to replace heart ventricles. The company generates revenue from the sale of these implantable units and external pneumatic drivers like the Companion 2 and Freedom Driver to hospitals.
BMRA
Biomerica
$4.73 Mn
1.56
+0.00%
-49.19%
Biomerica manufactures and sells diagnostic test kits, such as the hp detect and inFoods IBS tests, which analyze specimens to detect diseases and bacteria. These products are sold as diagnostic machines/tests to clinical laboratories and point-of-care settings, fitting the H-08 profile of selling the test rather than performing the service.
ITOC
iTonic Holdings
$4.49 Mn
0.28
+0.00%
-56.59%
The company develops and commercializes the FTTPS brachytherapy treatment planning system, which is registered as a Class III medical device. This system is used for radiotherapy planning in hospitals, fitting the description of therapeutic medical devices.
CLGN
2nd
CollPlant Biotechnologies
$4.26 Mn
0.31
-3.12%
-88.35%
The company manufactures and sells medical devices for implantation and wound care, specifically citing the VergenixSTR product sold to clinics and hospitals.
XAIR
Beyond Air
$4.26 Mn
5.73
+0.35%
+138.75%
Beyond Air designs and manufactures the LungFit® system, a medical device used to generate and deliver nitric oxide for treating pulmonary hypertension and other respiratory conditions. Revenue is primarily generated from the sale of these LungFit® PH devices to hospitals and healthcare providers.
POAS
2nd
Phaos Technology Holdings (Cayman)
$4.12 Mn
0.16
+0.00%
—
The company sells the PT-Biology (PT-B) series and other super-resolution imagers to R&D institutions and biomedical service providers for research and innovation activities. These products serve as life-sciences research tools for observing details beyond the conventional optical limit.
AIDX
2nd
20
$3.98 Mn
0.52
-5.45%
—
The company sells the BioCheck field test kit for screening suspicious powders for bioterror agents, which is a diagnostic test product sold to customers like fire departments.
ISCO
2nd
International Stem Cell
$3.92 Mn
0.49
+22.50%
+172.22%
Through its Lifeline Cell Technology business, the company sells over two hundred human cell-based items, including primary cells, stem cells, and specialized media, to academic, government, and industrial laboratories.
VVOS
Vivos Therapeutics
$3.91 Mn
0.29
-3.33%
-93.48%
Vivos Therapeutics sells proprietary oral appliances (such as Versa, Vida, and Tooth Positioners) and operates dental service organizations to treat maxillofacial abnormalities. Its core product is a non-surgical dental-based therapy for obstructive sleep apnea and snoring.
IVF
2nd
INVO Fertility
$3.28 Mn
1.43
-6.54%
-97.46%
The company designs, manufactures, and sells the INVOcell medical device to third-party fertility clinics to enable the intravaginal culture procedure.
NXGL
2nd
Nexgel
$3.09 Mn
0.38
+0.00%
-83.55%
The company has a dedicated Medical Devices segment developing products like the NEXDrape incise surgical drape and NEXDerm adhesive tape for securing lines.
AVCRF
Avricore Health
$3.04 Mn
0.03
+0.00%
-40.00%
Avricore Health sells the HealthTab point of care testing platform, which consists of analyzers and associated reagents for rapid blood analysis of biomarkers. Its revenue is generated from the sale, lease, or licensing of these diagnostic machines to pharmacy chains and independent pharmacists.
FEED
ENvue Medical
$2.65 Mn
0.43
-6.52%
-93.23%
The company designs and manufactures therapeutic and surgical medical devices, specifically ultrasound-based products like UroShield for biofilm prevention, PainShield for pain therapy, and the Envizion System for guiding feeding tube placement. These are regulated treatment devices sold to hospitals and distributors.
AMIX
Autonomix Medical
$2.63 Mn
6.17
-3.59%
-73.77%
Autonomix Medical designs and develops therapeutic and surgical medical devices, specifically a catheter-based microchip enabled sensing array and radiofrequency ablation system for treating nerve-related disorders. The company's anticipated revenue model is based on the sale of these devices to hospitals and interventional radiology suites.
OGEN
2nd
Oragenics
$2.39 Mn
0.53
-3.64%
-51.82%
The company designs and develops a proprietary breath-powered intranasal device used to administer its drug candidate. This device is a therapeutic medical device designed to close the soft palate and enhance nasal retention.
VYCO
Vycor Medical
$2.34 Mn
0.07
+0.00%
-46.15%
Vycor Medical designs, develops, and markets the ViewSite Brain Access System, a retractable access device used in brain and spine surgeries sold to hospitals and surgical centers. This fits the description of therapeutic and surgical medical devices.
ITP
2nd
It Tech Packaging
$2.31 Mn
0.17
+0.00%
-15.00%
The company generates revenue from the production and sale of medical face masks, which are medical consumables and disposable supplies.
VYST
2nd
Vystar
$2.22 Mn
0.09
-10.00%
-35.71%
The RxAir segment designs and manufactures air purification systems, specifically the RxAir 400, which is cleared as a Class II medical device by the FDA for use in healthcare environments like operating rooms.
VNRX
Volitionrx
$2.17 Mn
0.47
-6.00%
-96.56%
VolitionRx manufactures and sells clinical diagnostic equipment and tests, specifically the Nu. Q® NETs assay for sepsis and the Nu. Q® Cancer assays for lung cancer. Revenue is generated from the sale of diagnostic kits and reagents to hospital laboratories and clinical institutions.
BJDX
Bluejay Diagnostics
$1.92 Mn
0.97
-4.90%
-82.55%
Bluejay Diagnostics develops the Symphony technology platform, which consists of a diagnostic analyzer and single-use protein detection cartridges for in vitro diagnostics. The company intends to generate revenue from the sale of these analyzers and the recurring sale of the assays/cartridges used to run the tests.
TNON
Tenon Medical
$1.80 Mn
5.45
+10.77%
+283.80%
Tenon Medical designs and manufactures The Catamaran™ SI Joint Fusion System, which is a titanium implant used for sacroiliac joint fusion. This is a therapeutic surgical medical device sold to hospitals and outpatient surgery centers.
INBS
Intelligent Bio Solutions
$1.70 Mn
3.22
-4.45%
-78.53%
The company manufactures and sells the Intelligent Fingerprinting Drug Screening System, which consists of portable DSR Plus readers and single-use cartridges for point-of-care drug detection. This matches the description of in-vitro diagnostic analysers and point-of-care testing platforms.
ONCO
Onconetix
$1.68 Mn
0.75
-1.32%
-99.49%
Onconetix sells Proclarix, an in vitro diagnostic test for prostate cancer, to diagnostic laboratories, hospitals, and clinics. The company generates revenue from the sale of this diagnostic assay and its associated proprietary algorithm used to generate risk scores.
LUDG
2nd
Ludwig Enterprises
$1.67 Mn
0.01
-50.00%
-87.50%
The company sells at-home cheek swab collection kits, which are the physical diagnostic tools required to perform its proprietary mRNA-based tests.
NUMD
Nu-Med Plus
$1.67 Mn
0.02
+0.00%
-50.00%
Nu-Med Plus designs and manufactures therapeutic medical devices, specifically nitric oxide delivery systems including a bedside hospital delivery device, a clinical delivery unit, and a portable rechargeable device. These products are intended for clinical use in intensive care units and medical offices to deliver inhaled nitric oxide therapy.
NIMU
Non Invasive Monitoring Systems
$1.43 Mn
9.26
+8.81%
—
The company developed and manufactured motorized whole body periodic acceleration platforms used for mechanical therapy to improve circulation and muscle activation. These platforms were sold and leased as therapeutic medical devices to hospitals and rehabilitation centers.
BNBX
Bnb Plus
$1.25 Mn
0.15
+15.38%
-96.19%
The company's primary revenue is generated through LineaRx, which sells synthetic DNA templates, RNA production enzymes, and mRNA manufacturing kits to biotechnology firms and research institutions. These products are tools and reagents used for life-sciences research and bioproduction.
RGNT
Regentis Biomaterials
$1.13 Mn
1.99
-2.45%
—
Regentis Biomaterials develops GelrinC, a hydrogel implant and the Stelar delivery device, which are therapeutic medical devices used for treating articular cartilage defects in the knee. The company's target customers are hospitals, orthopedic surgery centers, and surgeons who perform these surgical procedures.
AEMD
Aethlon Medical
$1.11 Mn
2.89
-2.69%
-75.30%
Aethlon Medical develops the Hemopurifier, which is described as a clinical stage immunotherapeutic device designed to remove pathogens and vesicles from the bloodstream. This fits the description of a therapeutic medical device used for treatment in oncology and viral infections.
VRAX
Virax Biolabs
$1.10 Mn
2.76
-1.78%
-85.90%
The company focuses on the detection and diagnosis of viral diseases through in vitro diagnostics, specifically developing the ViraxImmune brand for immune profiling tests and assays. It sells diagnostic test kits for respiratory infections, oncology, and cardiac markers to healthcare providers and laboratories.
ODYY
Odyssey Health
$1.01 Mn
0.01
+0.00%
-66.67%
Odyssey Health develops and intends to market therapeutic and diagnostic medical devices, specifically the CardioMap heart monitoring device and the Save A Life choking rescue device. These products are designed for use by cardiologists, hospitals, and first responders, fitting the description of therapeutic and surgical medical devices.
ISPC
iSpecimen
$0.83 Mn
2.42
+12.56%
-94.83%
iSpecimen sells human biospecimens, including biofluids, tissues, and living cells, to life science researchers for use in discovery and development. These products are essential reagents and materials for life-sciences research, fitting the description of tools and consumables for bioproduction and research.
HCWB
2nd
HCW Biologics
$0.74 Mn
2.13
-15.48%
-47.01%
The company commercializes and sells specific reagents, HCW9201 and HCW9206, which are used by partners to improve the manufacturing of CAR T and natural killer cell therapies.
RMTG
2nd
Regenerative Medical Technology
$0.66 Mn
0.05
-16.67%
+25.00%
The company generates revenue from the sale of equipment and proprietary kits used by physicians to apply stem cell therapies.
WOK
WORK Medical Technology
$0.64 Mn
2.20
-5.58%
-100.00%
The company's primary revenue is derived from the manufacture and sale of disposable medical supplies and consumables, specifically endotracheal tubes, laryngeal mask airways, disposable breathing circuits, and nebulizer kits. These products are explicitly described as Class I and II disposables sold to hospitals and distributors.
VBIO
2nd
Valion Bio
$0.54 Mn
0.16
-11.11%
-95.17%
The company maintains a Bioelectronic Medicine program developing non-invasive cervical vagus nerve stimulation devices for neurologic, cardiac, and autoimmune conditions, which are therapeutic medical devices.
VTAK
Catheter Precision
$0.48 Mn
0.22
-4.35%
-94.82%
Catheter Precision designs and manufactures therapeutic and surgical medical devices, specifically the VIVO System for 3D cardiac mapping and the Amigo robotic arm for catheter control. These products are sold to hospitals and electrophysiology labs for use in cardiac ablation procedures.
RBOT
Vicarious Surgical
$0.48 Mn
0.04
-20.00%
-99.40%
Vicarious Surgical designs and manufactures the Vicarious Surgical System, a robotic platform for minimally invasive abdominal and gynecological procedures. The company's primary product is a therapeutic surgical robot consisting of a surgeon console, patient cart, and instrument arms.
PFSA
Profusa
$0.46 Mn
27.48
+506.62%
-34.92%
Profusa designs and manufactures therapeutic and surgical medical devices, specifically injectable hydrogel biosensors like Lumee Oxygen and Lumee Glucose. These are regulated medical devices intended for clinical use in wound care and diabetes management, sold to hospitals and clinics.
LYRA
2nd
Lyra Therapeutics
$0.43 Mn
0.24
-4.00%
-96.60%
The company's proprietary drug delivery technology involves a bioabsorbable mesh scaffold and an elastomeric matrix implant designed for an in-office procedure, which constitutes a therapeutic medical device.
NOTVQ
2nd
Inotiv
$0.35 Mn
0.01
+0.00%
-99.55%
Through its Research Models and Services (RMS) segment, the company sells research-quality animals, specialized disease models, and Teklad brand laboratory animal diet and bedding to academia, government clients, and pharmaceutical companies.
GCAN
2nd
Trafalgar International
$0.24 Mn
0.25
-24.24%
-44.44%
The company holds an exclusive worldwide license for an eluting transmucosal patch platform, which is a therapeutic medical device used for the noninvasive delivery of cannabinoids across mucosal membranes.
NUWE
Nuwellis
$0.22 Mn
1.19
-5.56%
-99.46%
Nuwellis designs, manufactures, and commercializes the Aquadex FlexFlow and Aquadex SmartFlow systems, which are medical devices used for ultrafiltration therapy to remove excess fluid and salt from patients. These systems are therapeutic devices sold to hospitals and healthcare providers for treating heart failure, critical care, and pediatric patients.
GCTK
Glucotrack
$0.21 Mn
0.34
+0.00%
-94.06%
Glucotrack designs and develops an implantable continuous blood glucose monitor, which is a therapeutic/surgical medical device. The company's core focus is the development of this intravascular sensor for patients with Type 1 and Type 2 diabetes.
GV
2nd
Visionary Holdings
$0.13 Mn
0.03
+0.00%
-98.40%
The company sells life sciences products including collagen probiotic and prebiotic series, gastrointestinal detection tools, and micro-ecological nutritional products.
SIGY
Sigyn Therapeutics
$0.05 Mn
0.03
+0.00%
-98.93%
Sigyn Therapeutics develops medical devices for extracorporeal blood purification, specifically the Sigyn Therapy device and the ImmunePrep, ChemoPrep, and ChemoPure platforms. These are therapeutic devices designed to remove pathogens, toxins, and chemotherapy agents from the bloodstream to treat cancer and infectious diseases.
GTHP
Guided Therapeutics
$0.01 Mn
0.22
+0.00%
-15.38%
Guided Therapeutics designs and manufactures the LuViva Advanced Cervical Scan, a medical device used for the noninvasive detection of cervical cancer. The company generates revenue from the sale of these therapeutic/diagnostic systems to distributors and government health programs.
SOBR
2nd
SOBR Safe
$0.00 Mn
0.53
+0.00%
-84.46%
The company manufactures the SOBRcheck and SOBRsure devices, which are regulated medical-grade wearables and sensors used for continuous alcohol monitoring and clinical behavioral health tracking.
ADTX
2nd
Aditxt
$0.00 Mn
0.00
—
-100.00%
Through its Pearsanta segment and Mitomic technology platform, the company develops mitochondrial DNA-based biomarkers and blood-based tests for the early detection of prostate cancer and endometriosis.
BDPT
2nd
Bioadaptives
$0.00 Mn
0.00
—
-100.00%
The company manufactures and sells the Lung Flute, which is explicitly described as a medical device supplied to medical clinics and senior care facilities.
SSKN
STRATA Skin Sciences
$0.00 Mn
0.00
—
-100.00%
STRATA Skin Sciences designs and manufactures therapeutic medical devices, specifically the XTRAC excimer laser systems, VTRAC lamp series, and TheraClear Acne Therapy System for treating dermatologic conditions. These are surgical/treatment devices used in physicians' offices to treat psoriasis, vitiligo, and acne.
