JNJ
2nd
Johnson & Johnson
$688.76Bn
286.11
+0.90%
+46.54%
The MedTech segment designs and manufactures therapeutic and surgical medical devices, including cardiovascular devices, orthopaedic implants, and robotic surgical technologies. These products are sold to hospitals and clinicians for use in acute and elective procedures.
TMO
Thermo Fisher Scientific
$259.44Bn
700.21
+0.09%
+20.70%
The company's Life Sciences Solutions and Analytical Instruments segments provide a vast portfolio of reagents, instruments, and consumables for biological and medical research, genomic and proteomic analysis, and electron microscopy. These products are sold to universities, research institutions, and biotech firms to support scientific research and bioproduction.
ABT
Abbott Laboratories
$187.98Bn
108.54
+1.17%
-16.03%
Abbott develops and sells a wide range of therapeutic medical devices, including pacemakers, defibrillators, stents, and glucose monitors, sold to hospitals and physicians.
DHR
Danaher
$163.91Bn
233.03
+0.38%
+5.35%
Danaher's Life Sciences and Biotechnology segments provide instruments, consumables, and software for bioprocessing, genomics, and proteomics used in laboratory research and biopharmaceutical manufacturing. These products are sold to research institutions and biotech companies to study biological molecules like DNA and RNA.
ISRG
Intuitive Surgical
$153.75Bn
443.59
+0.84%
-21.56%
Intuitive Surgical designs and manufactures robotic assisted surgical systems, specifically the da Vinci and Ion platforms, which are used for minimally invasive procedures. These are therapeutic and surgical medical devices sold to hospitals and ambulatory surgery centers.
MDT
Medtronic
$131.67Bn
102.86
+1.84%
+6.99%
Medtronic designs and manufactures a vast array of therapeutic and surgical medical devices, including implantable cardiac pacemakers, defibrillators, spinal implants, and robotic-assisted surgery systems. These products are sold to hospitals and physicians for the treatment of cardiovascular, neuroscience, and surgical conditions.
MCK
2nd
Mckesson
$127.33Bn
1,102.82
+2.40%
+30.32%
Through its Medical-Surgical Solutions segment, the company manufactures and sells its own proprietary line of medical-surgical supplies and consumables to physician offices and surgery centers.
SYK
Stryker
$117.84Bn
309.54
-0.91%
-17.11%
Stryker designs and manufactures a wide array of therapeutic and surgical medical devices, including orthopaedic implants for joint replacement, the Mako SmartRobotics platform, and neurocranial devices for brain surgery. These products are sold directly to hospitals and doctors for use in surgical procedures.
CAH
2nd
Cardinal Health
$64.97Bn
281.08
+1.06%
+36.41%
The company manufactures and sells its own branded medical-surgical and laboratory products, specifically mentioning gloves, syringes, wound care items, and surgical drapes.
BSX
Boston Scientific
$64.27Bn
44.34
+0.25%
-57.76%
Boston Scientific designs and manufactures therapeutic and surgical medical devices, including stent systems, catheters, implantable pacemakers, and neurostimulation platforms. These products are sold to hospitals and clinics for use in cardiovascular, respiratory, digestive, oncological, neurological, and urological conditions.
TEL
2nd
TE Connectivity
$62.00Bn
216.26
-0.68%
-8.47%
The company manufactures interventional medical components and products for medical imaging, diagnostic, surgical, and minimally invasive applications.
EW
Edwards Lifesciences
$61.69Bn
107.18
+1.25%
+24.47%
Edwards Lifesciences designs and manufactures therapeutic and surgical medical devices, specifically heart valves. Its revenue is driven by the sale of the SAPIEN family of transcatheter valves, the PASCAL and EVOQUE repair/replacement systems, and surgical tissue valves like INSPIRIS RESILIA.
AME
2nd
Ametek
$55.50Bn
242.04
+0.41%
+24.67%
The Electromechanical group designs and manufactures medical devices, including surgical instruments and implantable devices, sold to medical device makers.
IDXX
2nd
Idexx Laboratories
$55.49Bn
704.23
+0.89%
+0.39%
Idexx manufactures and sells clinical diagnostic equipment and tests, including point-of-care analyzers and water testing instrumentation like Colilert and Colisure for water utilities and government laboratories.
MDLN
Medline
$51.94Bn
39.47
-1.28%
—
Medline manufactures and sells a vast array of medical supplies and consumables, including wound care, exam gloves, protective apparel, and surgical procedure trays. These products are sold to hospitals, surgery centers, and physician offices as their core business.
A
Agilent Technologies
$49.04Bn
173.91
+0.51%
+18.39%
Agilent designs and manufactures life-sciences research tools and instruments, including liquid chromatography, gas chromatography, and mass spectrometry systems. These products are sold to pharmaceutical, biotechnology, and academic research institutions for drug discovery and chemical analysis.
WAT
Waters
$45.23Bn
460.23
-0.42%
+21.34%
Waters Corporation designs and manufactures analytical instruments, including HPLC, UPLC, and mass spectrometry systems, as well as chromatography columns and reagents. These products are sold as tools for life-sciences research and bioproduction to customers in pharmaceuticals, biotechnology, and academic research.
MTD
2nd
Mettler Toledo International
$37.71Bn
1,739.13
+0.43%
+23.15%
Mettler-Toledo designs and manufactures laboratory instruments, including balances, pipettes, and analyzers, which contribute approximately 56% of net sales and are used in life sciences research and development.
GEHC
GE HealthCare Technologies
$37.54Bn
83.02
+1.44%
+12.23%
The company's largest segments, Imaging and Advanced Visualization Solutions, focus on manufacturing clinical diagnostic equipment such as CT, MRI, X-ray, and Ultrasound systems. These products are sold to hospitals and health systems for the purpose of clinical diagnosis.
ALC
Alcon
$36.13Bn
74.13
+3.19%
-5.70%
Alcon's primary business involves the design and manufacture of therapeutic and surgical medical devices, specifically intraocular lenses (IOLs), phacoemulsification systems, and 3D visualization platforms for cataract and glaucoma surgeries.
RMD
Resmed
$33.69Bn
239.53
+0.25%
-4.99%
ResMed designs and manufactures therapeutic medical devices for sleep apnea and respiratory disorders, specifically CPAP, APAP, bilevel, and high flow therapy systems. These are regulated treatment devices sold to patients, hospitals, and home medical equipment providers.
IR
2nd
Ingersoll Rand
$32.68Bn
85.10
-0.23%
+11.68%
The Precision and Science Technologies segment designs and manufactures life science tools and single-use powder and liquid handling containment solutions for life science and medical applications.
ILMN
Illumina
$31.30Bn
207.01
-1.21%
+72.61%
Illumina designs and manufactures sequencing and array-based instruments, reagents, and library preparation kits used for genomics and proteomics research. Its primary revenue comes from selling these life-sciences research tools and consumables to research institutions, academic centers, and biotechnology companies.
DXCM
Dexcom
$31.08Bn
83.33
+2.38%
+39.53%
Dexcom designs and manufactures continuous glucose monitoring (CGM) systems, including the G7 and Stelo, which are wearable medical devices used for diabetes and metabolic health management. Revenue is primarily generated from the sale of this hardware, including sensors, transmitters, and receivers.
PHG
Koninklijke Philips
$29.22Bn
30.35
+1.00%
+4.94%
Philips' Diagnosis & Treatment segment is a core business driver, providing diagnostic imaging products including Magnetic Resonance Imaging, Ultrasound, Computed Tomography, and Diagnostic X-ray. These products are sold to healthcare providers and hospitals for clinical diagnosis.
WST
West Pharmaceutical Services
$29.09Bn
416.75
+1.29%
+56.29%
The company's primary business is the manufacture of primary proprietary packaging solutions for injectable drugs, specifically elastomer-based containment components such as stoppers, seals, plungers, and cartridge components. These are medical supplies and consumables sold to pharmaceutical and biologic companies for use in their injectable formulations.
STE
Steris
$25.67Bn
264.36
+4.22%
+1.51%
STERIS manufactures capital equipment for healthcare providers, including sterilizers, surgical tables, and automated endoscope reprocessors. These are therapeutic and surgical medical devices used in operating rooms and procedural centers.
FTV
2nd
Fortive
$20.25Bn
67.94
+0.13%
+30.75%
The Advanced Healthcare Solutions segment designs and manufactures therapeutic and surgical medical devices, including instrument sterilization systems and radiation detection and safety monitoring tools under brands like ASP and Landauer.
ZBH
Zimmer Biomet Holdings
$19.53Bn
103.22
-1.31%
+13.97%
Zimmer Biomet designs and manufactures therapeutic and surgical medical devices, specifically orthopedic reconstructive implants, knee and hip replacement systems, and thoracic devices. These products are sold to orthopedic surgeons, neurosurgeons, and hospitals for use in surgical procedures.
NDSN
2nd
Nordson
$18.09Bn
324.74
-0.57%
+39.28%
The Medical Interventional Solutions business provides therapeutic and surgical medical devices, including interventional delivery systems, balloons, and cardiovascular cannula for minimally invasive surgical procedures.
IEX
2nd
Idex
$17.45Bn
237.63
-0.20%
+42.24%
The Health & Science Technologies segment specifically produces biocompatible medical devices and implantables sold to medical device makers.
RVTY
Revvity
$17.25Bn
154.52
-1.64%
+65.44%
Revvity's Life Sciences segment sells a comprehensive portfolio of research tools, including radiometric detection reagents, microscopy imaging reagents, recombinant cell lines, and automated liquid handling platforms to pharmaceutical, biotech, and academic researchers.
CRL
2nd
Charles River Laboratories International
$16.18Bn
338.04
-0.84%
+99.78%
The Research Models and Services segment supplies purpose-bred rodents, large research models, and cell solutions used by clients for drug discovery and development activities.
SOLV
Solventum
$15.13Bn
89.05
+0.27%
+18.39%
Solventum's MedSurg segment sells therapeutic and surgical medical devices, including negative pressure wound therapy and surgical supplies. These products are designed to accelerate healing and mitigate patient risk during surgical operations.
GKOS
Glaukos
$14.53Bn
245.56
-0.25%
+167.47%
Glaukos generates the majority of its revenue from the sale of medical devices, specifically the iStent family of micro scale surgical devices used in Micro Invasive Glaucoma Surgery (MIGS). These products are sold directly to ambulatory surgery centers, hospitals, and physician private practices.
BAX
Baxter International
$13.35Bn
25.81
+0.27%
+38.02%
Baxter's core business involves the manufacture of medical supplies and consumables, specifically sterile intravenous (IV) solutions, infusion systems, administration sets, and parenteral nutrition therapies. These products are sold as disposables and consumables to hospitals and healthcare providers.
PEN
Penumbra
$12.65Bn
320.84
+0.02%
+15.10%
Penumbra designs and manufactures therapeutic and surgical medical devices, specifically for vascular and neurovascular conditions. Its product portfolio includes the INDIGO system for thrombectomy and the RUBY embolization platform, which are used by physicians in hospitals to remove blood clots and treat aneurysms.
COO
Cooper Companies
$11.91Bn
62.65
+0.74%
-12.68%
The company designs and manufactures therapeutic and surgical medical devices, including soft contact lenses (CooperVision) and surgical devices for gynecologic procedures and contraceptive products like Paragard (CooperSurgical). These products are sold to eye care practitioners, hospitals, and ambulatory surgery centers.
ALGN
Align Technology
$11.90Bn
168.32
+0.81%
+20.73%
Align Technology's primary business is the design and manufacture of clear aligners (Invisalign) and intraoral scanners (iTero) specifically for orthodontists and dental practitioners. The company's core revenue is derived from dental-specific products and services, fitting the definition of the Dental industry.
TECH
Bio-Techne
$11.43Bn
72.80
-0.05%
+19.84%
Bio-Techne's Protein Sciences segment sells high-quality biological reagents such as cytokines, growth factors, and antibodies, as well as proteomic analytical tools like western blot systems and multiplexed ELISA platforms for life science research and drug discovery.
HALO
2nd
Halozyme Therapeutics
$11.42Bn
100.27
-0.40%
+40.85%
The company designs and supplies drug-device combination products, specifically auto-injectors for self-administration, to partners such as Teva.
QGEN
Qiagen
$10.82Bn
49.90
-0.42%
+11.76%
QIAGEN provides tools, reagents, and consumables for life-sciences research, such as the QIAamp and QIAcube systems for DNA/RNA extraction. Its customer base includes academic research institutions and pharmaceutical and biotechnology companies engaged in drug discovery.
PODD
Insulet
$10.58Bn
152.48
+2.14%
-54.16%
Insulet designs and manufactures the Omnipod platform, which consists of tubeless insulin delivery pods and controllers used for the treatment of insulin-dependent diabetes. These are therapeutic medical devices sold to wholesalers, distributors, and consumers.
DCI
2nd
Donaldson
$10.05Bn
86.70
-0.36%
+0.13%
The Life Sciences segment sells bioprocessing equipment such as bioreactors and fermenters, as well as consumables including chromatography devices and reagents used for cell growth, separation, and purification.
BDX
Becton Dickinson
$9.90Bn
218.04
+1.07%
+43.67%
BD's Medical Essentials segment produces a vast array of consumables and disposables, including peripheral intravenous catheters, safety hypodermic syringes, needles, and sharps disposal systems. These products represent a core part of their revenue stream and match the description of medical supplies and consumables.
BIO
Bio-Rad Laboratories
$9.85Bn
366.15
-1.17%
+15.54%
Bio-Rad's Life Science segment develops and markets instruments, systems, reagents, and consumables used to separate, purify, and quantify biological materials for research and biopharmaceutical manufacturing. These products are sold to universities, medical schools, and biotechnology companies for use in laboratory environments.
MOG-A
2nd
Moog
$9.66Bn
339.79
-0.78%
+69.35%
Moog manufactures medical devices and components, specifically pumps and sets for enteral clinical nutrition and infusion therapy, as well as components for surgical handpieces.
GMED
Globus Medical
$9.56Bn
72.14
-0.21%
-14.11%
Globus Medical designs and manufactures therapeutic and surgical medical devices, specifically implantable devices for spinal, orthopedic, and neurosurgical procedures such as pedicle screw systems and interbody spacers. It also sells spinal cord stimulation systems and robotics platforms like ExcelsiusGPS for surgical guidance.
HSIC
2nd
Henry Schein
$9.53Bn
86.22
+0.09%
+17.56%
The Global Specialty Products segment manufactures and sells dental implants, biomaterials, and orthodontic products, competing directly with dental-specific firms like Straumann and Dentsply Sirona.
RGEN
Repligen
$9.51Bn
167.79
+0.76%
+11.44%
Repligen provides bioprocessing technologies, instruments, and consumables used in the manufacturing of biological drugs, such as XCell ATF cell retention systems and OPUS PrePacked Columns. Its revenue is generated from the sale of these life-sciences research and bioproduction tools to biopharmaceutical companies and CDMOs.
BRKR
Bruker
$9.41Bn
61.59
+2.09%
+47.38%
Bruker's core business is the development and manufacture of high-performance scientific instruments for life sciences research, including mass spectrometry (timsTOF), nuclear magnetic resonance (NMR) systems, and spatial biology platforms (CosMx). These tools are sold to academic, government, pharmaceutical, and biotechnology customers for molecular and cellular research.
HNGE
2nd
Hinge Health
$9.37Bn
115.40
-4.66%
+176.41%
The company designs and sells the Enso wearable nerve stimulation device, which is a regulated medical device used for pain relief as part of its care program.
ATR
2nd
Aptargroup
$9.06Bn
142.95
+0.87%
+18.93%
The company's Pharma segment produces therapeutic delivery devices, including nasal drug delivery spray pumps, metered dose inhaler valves, and digital health solutions for oncology and neurology.
TXG
10x Genomics
$7.65Bn
58.19
-1.54%
+255.90%
10x Genomics develops and sells instruments and consumables for life-sciences research, specifically the Chromium single cell platform and Visium and Xenium spatial platforms. Its customers include academic research institutions, government laboratories, and biotechnology firms using these tools for biological analysis.
BLCO
Bausch & Lomb
$7.54Bn
21.10
-0.24%
+34.48%
Bausch & Lomb manufactures a wide array of therapeutic and surgical medical devices, including intraocular lenses (enVista, Crystalens), phacoemulsification platforms (Stellaris Elite), and surgical instruments (Storz). These products are sold to hospitals, surgical centers, and eye care professionals.
TWST
Twist Bioscience
$6.99Bn
111.60
-2.29%
+273.24%
Twist Bioscience manufactures and sells synthetic genes, oligonucleotides, and next-generation sequencing tools (such as target enrichment probes and library preparation kits) used for research and bioproduction. These products are sold to biotech, pharma, and academic laboratories for applications like drug discovery and basic biological investigation.
LNTH
Lantheus Holdings
$6.64Bn
101.59
+0.34%
+91.25%
Lantheus primarily generates revenue from the sale of diagnostic imaging agents such as PYLARIFY for prostate cancer PET imaging, DEFINITY for ultrasound enhancement, and Neuraceq for amyloid PET imaging. These products are sold to hospitals and independent imaging centers to facilitate clinical diagnosis.
FMS
2nd
Fresenius Medical Care AG
$6.16Bn
22.04
+2.08%
-7.00%
The company designs and manufactures medical devices including hemodialysis machines, peritoneal dialysis cyclers, and water treatment systems sold to hospitals and clinics globally.
TFX
Teleflex
$6.15Bn
155.00
+1.22%
+41.63%
Teleflex designs and manufactures therapeutic and surgical medical devices, including vascular catheters, interventional platforms like the MANTA Vascular Closure device, and surgical instruments such as bariatric staplers. These products are sold to hospitals and healthcare providers for use in critical care and surgical applications.
GRFS
2nd
Grifols
$5.91Bn
8.69
-1.25%
-0.11%
The company has a dedicated Diagnostic segment that develops and sells in vitro diagnostic assays, nucleic acid testing platforms, and immunohematology analyzers for blood typing and infectious disease screening.
HAE
Haemonetics
$5.59Bn
122.87
+0.12%
+66.24%
Haemonetics designs and manufactures therapeutic and surgical medical devices, including vascular closure, sensor-guided technologies, and esophageal protection product lines for hospital-based interventions. It also sells capital equipment for plasma and blood collection.
MMSI
Merit Medical Systems
$5.19Bn
86.63
-0.07%
-0.88%
Merit Medical Systems designs and manufactures therapeutic and surgical medical devices, including stents, balloons, and delivery systems for cardiology, radiology, and endoscopy. Their core offerings include devices for vascular access, embolotherapy, and the EsophyX Z+ system for treating gastroesophageal reflux disease.
GRAL
2nd
Grail
$5.19Bn
115.89
-4.50%
+39.29%
The company develops and commercializes the Galleri screening tool and methylation technology, which functions as a molecular point-of-care testing platform for cancer detection.
MMED
MiniMed
$5.06Bn
17.99
+0.62%
—
MiniMed designs and manufactures therapeutic medical devices for diabetes management, specifically insulin pumps and smart pens. Its flagship product, the MiniMed 780G, is an automated insulin delivery system that combines pump technology with real-time glucose sensing.
LIVN
LivaNova
$5.03Bn
91.32
+1.24%
+65.43%
LivaNova designs and manufactures therapeutic and surgical medical devices, specifically heart-lung machines, oxygenators, and the VNS Therapy System for epilepsy and depression. These products are sold to hospitals, neurosurgeons, and perfusionists for use in surgical and clinical treatment.
STVN
Stevanato Group S.p.A
$4.78Bn
15.80
+10.41%
-30.27%
The company's primary revenue driver (88% from the Biopharmaceutical and Diagnostic Solutions segment) comes from the sale of drug containment products such as prefillable syringes, vials, cartridges, and ampoules, which are medical supplies and consumables.
OKLO
2nd
Oklo
$4.67Bn
23.93
-2.09%
-76.46%
Through its subsidiary Atomic Alchemy, the company produces and sells radioisotopes for medical research and other applications, which falls under the manufacture of clinical diagnostic and medical-grade isotopes.
NOVT
2nd
Novanta
$4.50Bn
118.88
+1.24%
+9.30%
The company designs and manufactures therapeutic and surgical medical devices, specifically medical insufflators, endoscopic pumps, and integrated operating room technologies used in minimally invasive surgery.
ICUI
Icu Medical
$4.48Bn
179.27
+1.11%
+29.41%
ICU Medical designs and manufactures therapeutic and surgical medical devices, including large volume pumps, ambulatory infusion pumps, hemodynamic monitors, and anesthesia equipment. These products are sold to acute care hospitals and clinics for use in critical care and surgical procedures.
ITGR
Integer Holdings
$4.31Bn
126.69
+0.18%
+86.17%
Integer Holdings designs and manufactures therapeutic and surgical medical devices, including catheter-based systems, implantable pulse generators, and minimally invasive surgery tools. Its revenue is derived from selling these components and finished devices to multinational medical device original equipment manufacturers.
MIR
2nd
Mirion Technologies
$4.30Bn
17.74
-1.06%
-26.14%
The company sells nuclear medicine products for patient dosing and medical diagnostics, as well as radiation therapy quality assurance hardware and software used in cancer centers.
HTFL
Heartflow
$4.25Bn
48.46
-19.13%
+56.63%
Heartflow sells a diagnostic test (FFR CT Analysis and Plaque Analysis) that uses AI and 3D modeling to diagnose coronary artery disease. The company generates revenue on a pay-per-click basis when physicians review these diagnostic analyses, fitting the model of selling a diagnostic test rather than performing the scan itself.
CDNA
2nd
CareDx
$4.09Bn
77.88
-2.42%
+390.74%
The company manufactures and sells diagnostic laboratory products and kits, including HLA typing kits like QTYPE and next-generation sequencing offerings like AlloSeq Tx, to hospitals and reference laboratories.
NVST
Envista Holdings
$3.93Bn
24.50
-0.65%
+23.18%
Envista Holdings is a global dental products company that designs and manufactures dental implants, orthodontic appliances (including Spark clear aligners), and restorative materials. Its primary customers are dental professionals, including orthodontists, periodontists, and general dentists.
PLSE
Pulse Biosciences
$3.70Bn
50.44
-3.46%
+256.72%
Pulse Biosciences designs and manufactures therapeutic medical devices, specifically the nPulse System and the Vybrance Percutaneous Electrode System, used for nonthermally ablating targeted cells in cardiology and soft tissue. These are surgical and treatment devices sold to hospitals and surgical centers.
AXGN
Axogen
$3.34Bn
55.93
+0.96%
+132.65%
Axogen designs and manufactures therapeutic medical devices for nerve repair, specifically the Axoguard product line (Nerve Connector, Nerve Protector, and Nerve Cap) which are cleared via the FDA 510(k) pathway. These products are sold to hospitals and surgery centers for use in surgical procedures to support nerve coaptation and neuroma prevention.
TMDX
TransMedics
$3.17Bn
91.38
-0.67%
-20.92%
TransMedics designs and manufactures the Organ Care System (OCS), a portable warm perfusion platform used for heart, lung, and liver transplantation. This is a therapeutic medical device sold to transplant centers and hospitals.
TLX
2nd
Telix Pharmaceuticals
$3.13Bn
9.23
-1.39%
-2.94%
The company sells diagnostic imaging agents and platforms, such as Illuccix and Gozellix, which are used for prostate cancer imaging in clinical settings.
BHC
2nd
Bausch Health Companies
$3.13Bn
8.35
+1.09%
+26.13%
The company sells aesthetic medical devices through Solta Medical, including laser-based skin resurfacing systems, and ophthalmic surgical equipment through Bausch + Lomb.
IRTC
2nd
iRhythm Holdings
$3.05Bn
91.91
-1.76%
-45.45%
The company designs and manufactures a proprietary wearable biosensor, a wire-free patch that adheres to the chest to record electrocardiogram data. This device is a regulated medical wearable that has received FDA clearance and CE marking for clinical use.
OSIS
2nd
Osi Systems
$3.03Bn
192.92
-1.55%
-29.30%
The Healthcare segment provides diagnostic imaging systems, ultrasound systems, and fetal Doppler devices to hospitals and clinics, which are clinical diagnostic equipment and tests.
VCEL
2nd
Vericel
$2.91Bn
56.96
-0.80%
+42.97%
The company sells medical technology and instruments used for the delivery of its therapies, specifically the MACI Arthro instruments used for arthroscopic delivery of the implant.
SXI
2nd
Standex International
$2.90Bn
240.33
-1.23%
+3.68%
The Scientific segment manufactures medical-grade and laboratory temperature-controlled equipment, including ultra-low temperature freezers, blood bank refrigerators, and environmental stability chambers sold to healthcare facilities and laboratories.
ATRC
AtriCure
$2.89Bn
56.84
+1.54%
+79.25%
AtriCure designs and manufactures therapeutic and surgical medical devices, specifically ablation platforms like the Isolator Synergy and left atrial appendage exclusion systems like AtriClip. These products are sold to hospitals and surgical centers for use in open heart and minimally invasive cardiac procedures.
IPGP
2nd
Ipg Photonics
$2.88Bn
67.78
-4.35%
-17.01%
The company sells laser solutions specifically for medical procedures and to medical device companies, representing a material portion of its non-industrial revenue.
RADX
2nd
Radiopharm Theranostics
$2.73Bn
0.77
+4.05%
-83.04%
The company develops diagnostic radiotracers and imaging agents, such as RAD101 for brain metastases and RAD301 for PET imaging, which are clinical diagnostic tests sold as products.
NEOG
Neogen
$2.45Bn
11.23
+0.36%
+76.30%
Neogen's primary revenue driver is its Food Safety segment (71.3% of sales), which develops and markets diagnostic test kits for pathogen, toxin, and allergen detection, as well as culture media. These products are sold to food producers, processors, and regulatory agencies like the USDA and FDA for clinical and safety diagnostics.
UFPT
Ufp Technologies
$2.36Bn
305.06
-0.28%
+30.20%
UFP Technologies designs and manufactures medical devices and components used in minimally invasive surgery, orthopedic implants, and wearables for customers like Intuitive Surgical and Stryker. While it operates as a contract partner, its primary output consists of therapeutic and surgical medical devices.
ALMR
Alamar Biosciences
$2.14Bn
30.81
-2.99%
—
Alamar Biosciences sells the ARGO HT instrument system and related consumable kits, reagents, and assay panels used for protein detection and analysis. Its customers are primarily academic research institutions, biopharmaceutical companies, and contract research organizations using the NULISA platform for research and translational proteomics.
ESTA
Establishment Labs Holdings
$2.11Bn
70.75
+3.10%
+9.27%
Establishment Labs designs and manufactures therapeutic and surgical medical devices, specifically the Motiva Implants silicone gel filled breast implants and the Motiva Flora tissue expander. These products are sold to hospitals, outpatient surgery centers, and plastic surgeons for use in breast aesthetics and reconstruction.
EPAC
2nd
Enerpac Tool
$2.01Bn
39.16
-0.23%
+0.88%
Through its Cortland Biomedical business, the company operates as a biomedical textile product development company, which falls under the manufacture of medical supplies and consumables.
AZTA
Azenta
$2.00Bn
45.65
+4.08%
+52.78%
Azenta sells a broad portfolio of life sciences research tools, including automated storage systems, cryogenic systems, and consumables like racks, tubes, and plates. These products are sold to pharmaceutical, biotechnology, and academic research institutions for sample exploration and management.
VCYT
2nd
Veracyte
$1.96Bn
24.33
-1.22%
-38.98%
The company sells in vitro diagnostic (IVD) kits, such as Prosigna, to hospitals and laboratories outside the United States. This represents a product-based revenue stream where the customer buys the test kit to perform the analysis locally.
MRVI
Maravai Lifesciences Holdings
$1.96Bn
7.54
-1.82%
+132.00%
Maravai sells complex nucleic acids, custom enzymes, and antibody-based solutions used for research and biopharmaceutical production. These products, including mRNA oligonucleotides and nucleoside triphosphates, are sold to biopharmaceutical companies, biotech firms, and academic research institutions as life-sciences research tools and bioprocessing supplies.
ASST
2nd
Strive
$1.90Bn
21.36
-4.00%
-7.13%
Through its subsidiary Semler Scientific, the company markets the QuantaFlo FDA cleared vascular testing device, which is a sensor-based product used for in-office blood flow tests. Revenue is derived from licensing fees and service agreements tied to the volume of tests performed using this diagnostic equipment.
XRAY
Dentsply Sirona
$1.82Bn
9.16
-0.87%
-16.35%
The company is the world's largest manufacturer of professional dental products, selling clear aligners (SureSmile), dental implants, and CAD/CAM systems (CEREC) to dental professionals and laboratories.
LMAT
Lemaitre Vascular
$1.79Bn
78.29
+0.82%
-12.66%
Lemaitre Vascular designs and manufactures therapeutic and surgical medical devices, including anastomotic clips, carotid shunts, embolectomy catheters, and valvulotomes. These products are sold primarily to hospitals and clinics for use by vascular and cardiac surgeons in open and minimally invasive procedures.
INSP
Inspire Medical Systems
$1.77Bn
61.17
+1.02%
-29.51%
Inspire Medical Systems designs and manufactures the Inspire system, a neurostimulation medical device used to treat obstructive sleep apnea. The company generates its primary revenue from selling this therapeutic implant to hospitals and ambulatory surgery centers.
KMTS
Kestra Medical Technologies
$1.70Bn
28.64
+0.07%
+14.97%
Kestra designs and manufactures the ASSURE WCD, a wearable cardioverter defibrillator used to treat patients at risk of sudden cardiac arrest. This is a therapeutic medical device that monitors heart rhythm and delivers defibrillation shocks.
PGEN
2nd
Precigen
$1.63Bn
4.54
-2.58%
+17.62%
Through its Exemplar subsidiary, the company sells genetically engineered porcine research models to academic and industry customers for use in drug discovery and preclinical studies.
BFLY
Butterfly Network
$1.62Bn
6.09
-8.83%
+194.20%
Butterfly Network manufactures and sells clinical diagnostic equipment, specifically handheld ultrasound devices like the Butterfly iQ3 and Butterfly iQ+, which are used for point-of-care imaging. Its revenue is driven by the sale of these diagnostic instruments and the associated AI-driven software and consumables.
OMCL
Omnicell
$1.61Bn
35.03
+0.23%
-1.49%
Omnicell designs and manufactures therapeutic and surgical medical devices, specifically automated dispensing cabinets and robotic compounding systems used for medication administration. These hardware products are sold to hospitals, health systems, and pharmacies to improve safety and efficiency in medication management.
ENOV
Enovis
$1.60Bn
27.65
+0.11%
-10.43%
Enovis designs and manufactures therapeutic and surgical medical devices, including implants for joint replacement, limb reconstruction, and foot & ankle procedures in its Reconstructive segment. It also produces orthopedic bracing and electrical stimulators for pain management and physical therapy in its Prevention & Recovery segment.
CNMD
Conmed
$1.51Bn
50.52
+0.18%
+16.76%
CONMED designs and manufactures therapeutic and surgical medical devices, including powered resection instruments, the Hall surgical brand of battery operated power tools, and electrosurgical generators. These products are sold to hospitals and surgery centers for use in orthopedics, general surgery, and gastroenterology.
PCRX
2nd
Pacira BioSciences
$1.45Bn
36.46
+0.00%
+54.36%
The company sells iovera°, a handheld cryogenic device used to deliver controlled cold to nerves for drug-free pain relief, which is a therapeutic medical device.
CHRN
ChronoScale Holdings
$1.45Bn
9.95
-8.38%
+107.72%
The company designs and manufactures wearable robotic exoskeletons for clinical and personal use, such as the EksoNR and Ekso Indego Therapy units. These are therapeutic and surgical medical devices used for physical rehabilitation and mobility for individuals with physical disabilities.
KRSA
2nd
Korsana Biosciences
$1.44Bn
31.65
+1.18%
+213.99%
The company's strategy for CYC 126 involves a 'closed loop monitoring system' and 'device technology' to individualize the dosing of anesthetic agents, indicating the development of a therapeutic medical device to accompany its pharmacological approach.
TNDM
Tandem Diabetes Care
$1.40Bn
20.07
+14.62%
+14.49%
Tandem Diabetes Care designs and manufactures durable insulin pump systems, specifically the t:slim X2 and Mobi platforms, which are therapeutic medical devices used for insulin delivery.
NVCR
NovoCure
$1.38Bn
11.83
+0.94%
+3.95%
NovoCure designs and manufactures therapeutic medical devices, specifically the Optune and Optune Lua systems, which deliver tumor treating fields therapy to patients with solid tumor cancers. Its revenue is generated primarily through the sale of these devices and associated accessory systems.
PRCT
PROCEPT BioRobotics
$1.37Bn
23.80
+1.23%
-21.76%
PROCEPT BioRobotics designs and manufactures the AquaBeam and HYDROS Robotic Systems, which are image-guided robotic platforms used for the surgical treatment of benign prostatic hyperplasia. These are therapeutic and surgical medical devices sold to hospitals and ambulatory surgery centers.
MNKD
2nd
Mannkind
$1.33Bn
4.13
-0.72%
-18.54%
The company designs and manufactures therapeutic medical devices, including a wearable insulin delivery device and the Furoscix subcutaneous furosemide infusor.
STAA
Staar Surgical
$1.32Bn
26.39
-1.46%
+1.38%
Staar Surgical designs and manufactures implantable lenses for the eye, specifically the Implantable Collamer Lens (ICL) and associated delivery systems. These are therapeutic surgical medical devices used by ophthalmic surgeons to treat myopia, hyperopia, and astigmatism.
NIMU
Non Invasive Monitoring Systems
$1.28Bn
8.26
+0.00%
+2,329.41%
The company developed and manufactured motorized whole body periodic acceleration platforms used for mechanical therapy to improve circulation and muscle activation. These platforms were sold and leased as therapeutic medical devices to hospitals and rehabilitation centers.
NKTR
2nd
Nektar Therapeutics
$1.28Bn
37.27
+0.05%
-30.92%
The company historically generated revenue from the sale of its proprietary polyethylene glycol (PEG) reagents, which are tools used in bioproduction and life-sciences research to enhance drug pharmacokinetics.
DRTS
Alpha Tau Medical
$1.18Bn
13.38
+0.15%
+245.74%
Alpha Tau Medical designs and manufactures the Alpha DaRT® technology, which consists of radioactive sources and specialized applicators used as localized radiation therapy for solid tumors. These products are therapeutic medical devices sold to oncology centers and hospitals for the treatment of cancers such as pancreatic adenocarcinoma and glioblastoma multiforme.
IART
Integra Lifesciences Holdings
$1.12Bn
14.40
+0.35%
+19.60%
Integra designs and manufactures therapeutic and surgical medical devices, including neurosurgical instruments, ICP monitoring systems, and cranial stabilization devices. These products are sold to hospitals and surgery centers for use in neurosurgery and neurocritical care.
SGP
2nd
SpyGlass Pharma
$1.10Bn
32.88
-1.32%
—
The company's lead product, the BIM IOL System, is a medical device that combines a drug pad with an intraocular lens (IOL) for implantation during cataract surgery. This constitutes the design and manufacture of a therapeutic surgical implant.
ATEC
Alphatec Holdings
$1.10Bn
7.07
+0.14%
-65.00%
Alphatec designs and manufactures spinal implants, instruments, and neuromonitoring systems used for the surgical treatment of spine disorders. These products are sold to hospitals and ambulatory surgery centers for use in spinal fusion and decompression procedures.
IRMD
Iradimed
$1.09Bn
85.35
+0.14%
+1.01%
Iradimed designs and manufactures therapeutic and surgical medical devices, specifically MRI compatible infusion pumps, patient vital signs monitors, and ferromagnetic detection devices. These products are sold to hospitals and acute care facilities to enable safe MRI procedures for critically ill patients.
SIBN
Si-Bone
$1.05Bn
23.44
-2.90%
+35.81%
SI-BONE designs and manufactures titanium implants and associated instruments used to stabilize bone and promote fusion in the sacroiliac joint. These are therapeutic and surgical medical devices sold to hospitals, ambulatory surgery centers, and physicians.
AHCO
2nd
AdaptHealth
$1.05Bn
7.66
-2.67%
-17.90%
A significant portion of revenue (approximately 63%) is derived from the sale of medical supplies and consumables, such as PAP masks, continuous glucose monitors, wound care products, and incontinence supplies.
CBLL
Ceribell
$1.01Bn
26.14
-0.80%
+109.29%
Ceribell sells the Ceribell System, which includes the Clarity recorder device and AI-powered algorithms for the rapid diagnosis and continuous monitoring of seizures and delirium. These are clinical diagnostic tools sold to hospitals for point-of-care EEG testing, fitting the description of diagnostic equipment and assays.
CYRX
2nd
Cryoport
$1.01Bn
19.89
-1.04%
+127.05%
Cryoport provides bioprocessing and research-related tools through its IntegriCell cryopreservation services and BioStorage solutions used for preclinical and early-stage clinical materials.
DBVT
2nd
DBV Technologies
$994.06Mn
11.02
-3.59%
-15.62%
The company designs and manufactures the Viaskin patch, a therapeutic medical device used to deliver biologically active compounds through the skin to treat allergies.
AORT
Artivion
$931.88Mn
19.10
-1.50%
-58.10%
Artivion designs and manufactures therapeutic and surgical medical devices, specifically aortic stent grafts (e.g., E-vita Open NEO), mechanical heart valves (On-X), and surgical sealants (BioGlue). These products are sold to hospitals and healthcare facilities for use by surgeons in cardiac and vascular procedures.
AHG
2nd
Akso Health
$917.84Mn
1.27
-5.93%
-13.61%
The company engages in the bulk purchase and resale of medical devices, specifically citing the sale of Class III defibrillators and Class II anesthesia laryngoscopes to hospitals and clinics.
BVS
Bioventus
$898.22Mn
10.66
-1.84%
+40.82%
Bioventus designs and manufactures therapeutic and surgical medical devices, including peripheral nerve stimulation devices (StimRouter, Talismann), ultrasonic surgical platforms (neXus BoneScalpel), and ultrasound bone stimulation systems (EXOGEN). These products are sold to physicians, hospitals, and ambulatory surgical centers for use in orthopedic and neurosurgical procedures.
THRM
2nd
Gentherm
$893.07Mn
29.08
+1.01%
-19.51%
The company's Medical segment designs and manufactures patient temperature management systems for hyperthermia and hypothermia therapy used in intensive care and surgical procedures.
BBNX
Beta Bionics
$892.64Mn
16.42
-0.55%
-37.42%
Beta Bionics designs and manufactures the iLet Bionic Pancreas, which is a therapeutic medical device used for insulin delivery in patients with diabetes. The company generates revenue from the sale of this device to individual patients and healthcare providers.
KIDS
Orthopediatrics
$844.67Mn
32.35
-0.68%
+91.19%
OrthoPediatrics designs and manufactures therapeutic and surgical medical devices, specifically orthopedic implants, instruments, and robotic insertion tools for pediatric patients. Its revenue is primarily generated from the sale of trauma plating systems, flexible intramedullary nails, and spinal implants.
INMD
InMode
$840.77Mn
13.27
+0.61%
-7.20%
InMode designs and manufactures energy-based minimally invasive surgical medical treatment solutions, such as the BodyTite and Morpheus8 platforms, which are used for face and body contouring. These products are therapeutic and surgical medical devices sold to plastic surgeons, dermatologists, and OB/GYNs.
MLAB
Mesa Laboratories
$781.31Mn
139.01
+2.82%
+83.25%
Mesa Laboratories designs and manufactures life sciences tools, including the MassARRAY system for genomic testing and Gyrolab systems for protein analysis and peptide synthesis. These products, along with their associated chips, panels, and reagents, are sold to biopharma R&D teams, academic laboratories, and clinical research labs.
CTKB
Cytek Biosciences
$763.71Mn
5.84
+5.80%
+27.79%
Cytek Biosciences develops and sells flow cytometry instruments, such as the Aurora and Northern Lights systems, and reagents like cFluor and Tonbo for high-dimensional single cell analysis. Its primary customers are pharmaceutical companies, biopharma firms, and academic research centers using these tools for drug discovery and research in oncology and immunology.
VREX
Varex Imaging
$762.88Mn
18.10
-0.93%
+50.58%
Varex designs and manufactures X-ray tubes, flat panel and photon counting detectors, and image processing software used in computed tomography, mammography, and fluoroscopy. These products are sold to OEMs and end-users for clinical diagnostic radiology modalities.
QDEL
QuidelOrtho
$736.76Mn
10.74
+1.13%
-51.58%
QuidelOrtho manufactures and sells clinical diagnostic equipment and tests, including the VITROS platform for clinical chemistry and the ORTHO VISION platform for immunohematology. Its revenue model is based on the sale of instruments and a recurring stream of assays, reagents, and consumables.
OABI
2nd
OmniAb
$716.15Mn
4.91
-0.81%
+223.03%
Through its xPloration segment, the company sells instruments and related consumables used in antibody discovery and optimization workflows to external customers.
DCTH
Delcath Systems
$714.55Mn
20.55
-3.88%
+138.68%
Delcath Systems designs and manufactures therapeutic medical devices, specifically the CHEMOSAT hepatic delivery system and the HEPZATO KIT drug/device combination, used for percutaneous hepatic perfusion procedures to treat liver cancers. These products are sold to hospitals and cancer centers for surgical/interventional use.
VVVV
vVARDIS Holding AG
$658.74Mn
16.49
-8.39%
—
vVARDIS develops and sells Curodont® products specifically for the treatment of early-stage cavities, targeting dental professionals, general dentists, and dental service organizations (DSOs). Its core business is the commercialization of restorative dental treatments used in dental practices.
DNA
2nd
Ginkgo Bioworks Holdings
$621.11Mn
9.63
-5.77%
+20.38%
The company sells standardized tools and data assets, such as RAC systems and Datapoints, which are used for life-sciences research and bioproduction.
PACB
Pacific Biosciences Of California
$611.98Mn
1.96
-0.51%
+20.25%
Pacific Biosciences designs and manufactures sequencing instruments such as the Revio, Vega, and Sequel platforms, as well as proprietary consumables like SMRT cells and reagent kits. These products are sold to academic, governmental, and commercial research institutions for life-sciences research and genomic analysis.
TCMD
Tactile Systems Technology
$603.12Mn
26.81
-0.04%
+10.01%
The company designs and manufactures therapeutic medical devices, specifically pneumatic compression systems (Flexitouch Plus, Entre Plus, Nimbl) for lymphedema and the AffloVest wearable vest for airway clearance. These are treatment devices used for chronic vascular and respiratory conditions, fitting the definition of therapeutic medical devices.
SGHT
Sight Sciences
$598.02Mn
10.83
-1.46%
+53.62%
Sight Sciences designs and manufactures therapeutic and surgical medical devices, specifically the OMNI Surgical System and SION Surgical Instrument for glaucoma and the TearCare system for dry eye disease. These products are sold to healthcare providers for use in minimally invasive surgical procedures.
SENS
Senseonics Holdings
$579.52Mn
10.58
+5.38%
+71.20%
Senseonics designs and manufactures the Eversense CGM system, which consists of an implantable sensor and a removable smart transmitter. These are therapeutic/monitoring medical devices used for diabetes management, fitting the description of medical devices.
NNNN
Anbio Biotechnology
$549.66Mn
3.82
+0.53%
-83.61%
Anbio Biotechnology designs and sells in vitro diagnostic kits and instruments, including real-time PCR and chemiluminescence immunoassay products. Its revenue is derived from the sale of these diagnostic machines and the associated assays to hospitals, clinics, and laboratories.
MYGN
2nd
Myriad Genetics
$541.66Mn
5.66
-0.35%
-10.87%
The company develops and commercializes diagnostic assays and companion diagnostics, such as BRACAnalysis CDx and MyChoice CDx, which are sold as specific diagnostic products to laboratories and providers.
AVR
Anteris Technologies Global
$528.41Mn
5.42
-7.51%
+43.01%
Anteris Technologies Global designs and manufactures therapeutic medical devices for cardiac care, specifically the DurAVR® THV System and the ComASUR® Delivery System for treating aortic stenosis. These are surgical implants and delivery tools used in transcatheter aortic valve replacement (TAVR) procedures.
RCEL
AVITA Medical
$483.94Mn
15.63
-3.52%
+317.91%
AVITA Medical designs and manufactures therapeutic medical devices for acute wound care, specifically the RECELL autologous cell harvesting device used for treating thermal burns and full-thickness skin defects. These are regulated surgical instruments sold to hospitals, burn centers, and trauma centers.
CARL
Carlsmed
$469.16Mn
17.12
-1.04%
+34.59%
Carlsmed designs and manufactures patient-specific interbody implants and single-use surgical instruments for lumbar and cervical spine fusion surgery. These products are therapeutic medical devices sold to hospitals and ambulatory surgical centers.
MDXG
Mimedx
$468.42Mn
3.21
-0.93%
-57.03%
Mimedx designs and manufactures therapeutic tissue-based products, including allografts and xenografts like EPIFIX and EPICORD, used for surgical reinforcement and wound healing. These products are sold as medical devices for use in hospitals, surgical centers, and physician offices.
OBIO
Orchestra BioMed Holdings
$445.53Mn
7.25
+17.89%
+73.44%
Orchestra BioMed designs and develops therapeutic medical devices, specifically the AVIM Therapy for hypertension and the Virtue Sirolimus AngioInfusion Balloon for artery disease. These products are cardiovascular and interventional devices intended for clinical use in patients.
TKNO
Alpha Teknova
$440.90Mn
8.21
-1.08%
+85.33%
Alpha Teknova manufactures and sells reagents, pre-poured media plates, and liquid microbial culture media used for life-sciences research and bioproduction. Its Lab Essentials segment, which contributes 76.6% of revenue, specifically provides RUO formulations for applications like next generation sequencing and spatial biology.
MOBI
Mobia Medical
$438.90Mn
13.17
-1.05%
—
Mobia Medical designs and manufactures the Vivistim Paired Vagus Nerve Stimulation System, which consists of an implanted pulse generator and lead. This is a therapeutic medical device used for stroke recovery and neurorehabilitation.
SI
Shoulder Innovations
$432.88Mn
20.69
-1.62%
+40.75%
Shoulder Innovations designs and manufactures therapeutic medical devices, specifically anatomic and total shoulder implant systems for arthroplasty. Its revenue is primarily generated from the sale of these orthopedic implants to hospitals and ambulatory surgery centers.
CERS
Cerus
$401.89Mn
1.99
+2.58%
+24.38%
Cerus designs and manufactures the INTERCEPT Blood System, which includes the INTERCEPT Illuminator (an LED-based device) used to inactivate pathogens in blood components. These are therapeutic/treatment devices sold to blood centers and hospitals.
MASS
2nd
908 Devices
$400.01Mn
9.74
-0.51%
+67.64%
The company sells its handheld chemical analysis devices to life science researchers for laboratory and field work, providing tools for research and bioproduction analysis.
BWAY
Brainsway
$395.97Mn
10.11
-1.37%
+26.22%
BrainsWay designs and manufactures the Deep Transcranial Magnetic Stimulation (Deep TMS) system, which is a therapeutic medical device used to treat major depressive disorder and OCD. Revenue is generated from the sale, leasing, and servicing of these hardware systems to psychiatrists, hospitals, and clinics.
MTLS
2nd
Materialise
$383.35Mn
6.49
-1.52%
+6.22%
Materialise designs and manufactures personalized medical devices, including 3D printed surgical guides and patient-specific implants, sold to healthcare providers and medtech companies.
EMBC
Embecta
$366.02Mn
6.46
+0.47%
-55.17%
Embecta designs and manufactures therapeutic medical devices for diabetes management, specifically pen needles and insulin syringes. These products are used for the administration of insulin and other diabetes medications, fitting the description of treatment devices.
VMD
2nd
Viemed Healthcare
$348.95Mn
9.17
+0.66%
+43.06%
The company generates significant revenue from the rental and sale of home medical equipment and consumables, including ventilators, BiPAP, CPAP devices, oxygen concentrators, and breast pumps.
TMCI
Treace Medical Concepts
$345.50Mn
5.27
-1.31%
+67.83%
Treace Medical Concepts designs and manufactures therapeutic and surgical medical devices, specifically the Lapiplasty 3D Bunion Correction System and the Adductoplasty Midfoot Correction System. Its revenue is generated from the sale of these implants and surgical instruments to hospitals and surgical practitioners.
SSII
SS Innovations International
$332.28Mn
1.66
+25.76%
-74.10%
The company designs, manufactures, and markets the SSi Mantra Surgical Robotic System, which is used for various surgical procedures including urology and cardiac surgeries. Its revenue is derived from the sale of these surgical robots and related instruments.
CV
CapsoVision
$323.03Mn
6.03
-3.83%
+6.35%
CapsoVision manufactures and sells the CapsoCam capsule endoscopy system, which is a clinical diagnostic tool used to visualize and detect pathologies in the small bowel and colon. Revenue is generated from the sale of these diagnostic capsules and associated software platforms like CapsoCloud and CapsoView.
SMTI
Sanara MedTech
$297.07Mn
32.35
-0.58%
+64.97%
Sanara MedTech designs and markets therapeutic surgical products, specifically bone fusion products like BiFORM and ALLOCYTE Plus, and soft tissue repair grafts like TEXAGEN and FORTIFY TRG, which are used in orthopedic, spine, and trauma surgeries.
NAUT
Nautilus Biotechnology
$295.40Mn
2.32
-2.52%
+22.75%
Nautilus Biotechnology develops the Nautilus Voyager system, which is a life-sciences research tool for single molecule protein analysis. The company targets academic, biopharmaceutical, and research institutions for drug discovery and basic biology, selling instruments and recurring consumables like flow cells and reagent kits.
OFIX
Orthofix Medical
$292.25Mn
7.17
+3.31%
-52.23%
Orthofix designs and manufactures therapeutic and surgical medical devices, specifically spinal implants (pedicle screw systems, interbody spacers) and limb reconstruction systems (TrueLok external fixation, Fitbone intramedullary lengthening). These products are sold to hospitals and ambulatory surgery centers for the treatment of musculoskeletal pathologies.
TTRX
2nd
Turn Therapeutics
$285.85Mn
9.35
-7.70%
+128.61%
The company has a Medical Device Licensing segment that monetizes FDA-cleared therapeutic devices, such as antimicrobial gauze (K183681) and dermatitis management products (K171191), through licenses with partners like Medline.
LAB
Standard Biotools
$280.22Mn
0.71
+9.23%
-40.83%
Standard BioTools develops and sells instrumentation, consumables, and reagents for proteomics and genomics research, specifically through its CyTOF, Hyperion, and Biomark platforms. Its customers are research institutions and biopharmaceutical companies, and the profile explicitly states its products are marketed for research use only and not for clinical diagnostics.
PRE
Prenetics Global
$278.59Mn
16.51
-1.26%
+22.57%
Prenetics operates ACT Genomics, which provides FDA-cleared comprehensive genomic profiling tests for solid tumors to hospitals and physicians. This activity involves selling diagnostic tests and the associated genomic profiling services for clinical use in oncology.
CLPT
ClearPoint Neuro
$271.80Mn
8.48
-0.12%
-45.29%
ClearPoint Neuro designs and manufactures therapeutic and surgical medical devices, including the ClearPoint system for deep brain stimulation and the SmartFrame OR Stereotactic System. Its revenue is driven by the sale of reusable hardware and high-margin disposable components like cannulas and catheters used in neurosurgical procedures.
PROF
Profound Medical
$271.77Mn
7.42
-0.27%
+16.85%
Profound Medical designs and manufactures therapeutic medical devices, specifically the TULSA PRO and Sonalleve systems, which are used for the ablation of prostate tissue and uterine fibroids. Revenue is generated from the sale of this capital equipment and related service contracts.
ACU
Acme United
$271.39Mn
68.40
-2.58%
+84.12%
Acme United designs, manufactures, and distributes first aid kits and medical supplies under brands like First Aid Only and PhysiciansCare. These products are consumables and disposables, which aligns with the Medical Supplies industry.
NPCE
NeuroPace
$260.31Mn
7.56
-37.10%
-40.98%
NeuroPace designs and manufactures the RNS System, a brain responsive neurostimulation device used to treat drug resistant epilepsy. The company generates revenue from the sale of the neurostimulator, cortical and depth leads, and related accessories to hospitals and epilepsy centers.
DDD
2nd
3D Systems
$254.52Mn
1.53
-6.13%
-29.17%
The company provides surgical planning tools, implants, and instrumentation for hospitals and medical device companies through its Healthcare Solutions segment.
IMMP
2nd
Immutep
$254.11Mn
3.48
-4.66%
+89.13%
The company generates income through its subsidiary, Immutep S A S, which manufactures and distributes research reagents to scientists via third-party distributors such as Adipogen and Enzo.
QSI
Quantum-Si
$251.83Mn
1.15
-5.74%
-17.27%
Quantum-Si sells the Platinum and Platinum Pro protein sequencers, as well as consumable kits (Library Preparation, Barcoding, and Sequencing Kits), which are tools and reagents used for life-sciences research in proteomics. Its customers include academic research institutions, biopharmaceutical companies, and industrial laboratories using the platform for biomarker discovery and vaccine development.
NNBR
2nd
Nn
$250.71Mn
3.04
-0.98%
+104.03%
The company manufactures medical tools for orthopedics and surgical applications, which are sold as components and instruments for the medical market.
OSUR
Orasure Technologies
$249.91Mn
3.62
+0.00%
+58.77%
The company's primary business is the development and manufacture of diagnostic products, including rapid point-of-care tests for HIV, hepatitis C, and COVID-19. It generates significant revenue from the sale of these diagnostic test kits and related instruments to hospitals, clinics, and public health organizations.
LFCR
2nd
Lifecore Biomedical, Inc. \De\
$237.71Mn
6.42
+0.31%
-18.63%
The company manufactures and sells pharmaceutical grade non-animal sourced hyaluronic acid (HA) in bulk form as a raw material for customers' use in various medical applications.
BCYC
2nd
Bicycle Therapeutics
$235.88Mn
3.37
-2.32%
-48.94%
The company develops Bicycle imaging agents used to validate targets before therapeutic development, which falls under the category of diagnostic equipment and tests.
RELL
2nd
Richardson Electronics
$233.06Mn
18.15
-8.05%
+73.19%
The company manufactures, repairs, and distributes high-value replacement parts for diagnostic imaging, specifically CT and MRI tubes and RF amplifiers, sold to hospitals and medical centers.
UTMD
Utah Medical Products
$228.50Mn
71.97
-2.25%
+28.27%
The company designs and manufactures therapeutic and surgical medical devices, specifically fetal monitoring accessories, intrauterine pressure catheters, and vacuum assisted delivery systems. These products are sold directly to hospitals, labor and delivery suites, and neonatal intensive care units.
RXST
RxSight
$223.05Mn
5.32
-1.12%
-44.47%
RxSight designs and manufactures therapeutic medical devices, specifically the Light Adjustable Lens (an intraocular implant) and the Light Delivery Device used for postoperative adjustments. The company generates revenue from the sale of these surgical devices to eye care providers, hospitals, and ambulatory surgical centers.
ACIU
2nd
AC Immune
$216.71Mn
2.13
-0.47%
-34.06%
The company has a dedicated Diagnostics segment focused on developing positron emission tomography (PET) tracers, such as PI-2620 and ACI-12589, which are used as diagnostic imaging agents to detect protein aggregates in the brain.
PDEX
Pro Dex
$210.33Mn
65.66
-2.61%
+106.22%
Pro-Dex designs and manufactures surgical drivers and shavers used in orthopedic, thoracic, and craniomaxillofacial markets. These are therapeutic and surgical medical devices sold to original equipment manufacturers (OEMs).
ELMD
Electromed
$200.31Mn
24.32
-2.60%
-7.70%
Electromed designs and manufactures the SmartVest System, a therapeutic medical device utilizing high frequency chest wall oscillation technology to help patients clear lung secretions. The company's revenue is primarily derived from the sale of these devices, including the SmartVest SQL and SmartVest Clearway models.
ANIK
Anika Therapeutics
$179.50Mn
13.40
-2.97%
+32.67%
Anika Therapeutics designs and manufactures therapeutic medical devices and biomaterials, such as the Integrity scaffold for rotator cuff and tendon repairs and Tactoset for bone substitute. These products are sold directly to hospitals, ambulatory surgery centers, and physicians for surgical use.
SEER
Seer
$174.87Mn
1.57
-1.26%
-23.04%
Seer sells the Proteograph Product Suite, which consists of life-sciences research tools including the SP200 automation instrument and consumable assays (Proteograph ONE and DIRECT) used for deep proteomic analysis. These products are sold to academic institutions and biopharmaceutical companies for basic research and biomarker discovery.
KRMD
KORU Medical Systems
$171.59Mn
3.70
+0.27%
-14.94%
KORU Medical designs and manufactures therapeutic medical devices, specifically the FREEDOM Infusion System, which includes syringe drivers used for delivering immunoglobulin. These are mechanical treatment devices sold to specialty pharmacies and home infusion providers.
SKYA
SkyAI
$166.49Mn
2.32
-5.31%
-27.73%
The company generates revenue primarily through the sale of syringe products and related drug delivery systems. These are described as medical supplies and consumables sold to hospitals, clinics, and healthcare providers.
HUMA
2nd
Humacyte
$155.57Mn
0.56
-6.67%
-52.94%
The company's products, such as the Symvess vascular conduit, are used as surgical implants for extremity arterial injury and hemodialysis access, functioning as therapeutic medical devices.
FOCL
Edap Tms
$152.99Mn
3.24
-4.99%
+52.83%
EDAP TMS designs and manufactures therapeutic medical devices, specifically the Focal One Robotic HIFU system used for treating prostate cancer and endometriosis. The company's primary revenue is generated from the sale of this capital equipment and related maintenance and service contracts.
INGN
Inogen
$149.06Mn
5.69
+1.25%
-17.30%
Inogen designs and manufactures therapeutic medical devices, specifically portable and stationary oxygen concentrators, airway clearance devices, and CPAP masks. These products are used to treat chronic respiratory conditions and are sold as medical-grade hardware.
HSDT
2nd
Solana
$147.09Mn
1.73
-8.47%
-64.77%
The company develops, manufactures, and sells the Portable Neuromodulation Stimulator (PoNS), a non-implantable medical device used to treat gait and balance deficits in patients with neurological conditions.
INO
2nd
Inovio Pharmaceuticals
$141.05Mn
1.43
-2.05%
-26.67%
The company designs and sells a broad product line of CELLECTRA electroporation delivery devices used to enable in vivo protein production for its medicines.
BNR
2nd
Burning Rock Biotech
$140.21Mn
13.33
+0.68%
+9.17%
Through its In-Hospital Model, the company sells turnkey laboratory solutions and recurring reagent kits to hospitals, which constitutes the sale of diagnostic equipment and the consumables required to run them.
QTRX
Quanterix
$139.03Mn
2.93
+2.45%
-44.92%
Quanterix primarily sells life-sciences research tools, including the Simoa and Spatial Biology instruments (HD-X, SR-X, SP-X, PhenoCycler), as well as the associated assay kits, consumables, and reagents used by academic research labs and biopharmaceutical firms.
MOVE
2nd
Corvex
$129.66Mn
4.47
-5.10%
-40.79%
The company develops and sells the FDA-cleared Medical Ring, which is a regulated medical device used for pulse oximetry and remote patient monitoring.
CDXS
Codexis
$127.04Mn
1.16
+20.83%
-28.83%
Codexis sells engineered enzymes and proteins as biocatalysts and provides the CodeEvolver technology platform for bioproduction. Its revenue is derived from the sale of these research and production tools to pharmaceutical and biotechnology firms.
ZSQR
2nd
Z Squared
$126.14Mn
2.38
-3.64%
-83.18%
The company is developing the CD38-Diagnostic program, a diagnostic tool intended for healthcare providers to identify patients who would benefit from specific monoclonal antibody therapies.
LUNG
Pulmonx
$124.55Mn
2.86
-4.67%
+79.87%
Pulmonx designs and manufactures therapeutic medical devices, specifically the Zephyr Valve and associated delivery catheters used for lung volume reduction in emphysema patients. These are surgical/interventional implants sold to hospitals and healthcare providers.
MXCT
Maxcyte
$122.85Mn
1.19
+0.00%
-21.19%
MaxCyte sells the ExPERT family of instruments, proprietary processing assemblies (PAs), and consumables like electroporation buffers used for cell engineering and bioproduction. These products are sold to biopharmaceutical companies, academic institutions, and government research organizations for life-sciences research and development.
APYX
Apyx Medical
$118.37Mn
2.81
-2.77%
-30.96%
Apyx Medical designs and manufactures therapeutic and surgical medical devices, specifically the Helium Plasma Platform (Renuvion) and the AYON Body Contouring System. These products are sold to physicians, cosmetic surgery clinics, and surgical centers for use in skin tightening and fat removal procedures.
CATX
2nd
Perspective Therapeutics
$114.72Mn
0.95
+11.76%
-54.11%
The company develops and sells companion imaging agents using the isotope Lead 203 for patient selection and dosimetry, which are clinical diagnostic tools used to identify suitable patients for therapy.
PARK
Park Dental Partners
$108.75Mn
21.49
+1.42%
—
Park Dental Partners operates as a dental resource organization supporting a network of 86 practice locations providing general and specialty dentistry. Its revenue is derived from dental services including cleanings, fillings, oral surgery, and orthodontics.
STIM
Neuronetics
$108.04Mn
1.39
-2.80%
-31.86%
Neuronetics designs and manufactures the NeuroStar Advanced Therapy System, a transcranial magnetic stimulation (TMS) device used to treat major depressive disorder and OCD. The company generates significant revenue from the sale of this capital equipment and associated service and repair contracts.
SKIN
SkinHealth Systems
$106.10Mn
16.31
+2.19%
+1,154.62%
The company designs and manufactures therapeutic medical devices for skin health, specifically the Syndeo, Elite Tower, and Allegro devices, as well as SkinStylus microneedling systems. These are sold as durable capital equipment to professional medical providers, dermatologists, and plastic surgeons.
RANI
2nd
Rani Therapeutics Holdings
$105.47Mn
0.53
+0.00%
-72.54%
The company's core technology is the RaniPill, a proprietary drug-agnostic oral delivery capsule designed to enable the administration of large molecules. This device-based platform is the primary mechanism used to achieve bioavailability comparable to subcutaneous injection.
ORGO
Organogenesis Holdings
$105.13Mn
0.81
-15.62%
-86.96%
Organogenesis designs and manufactures therapeutic medical devices and regenerative medicine products, such as PuraForce reinforcement matrix for tendon and ligament repair and NuShield placental allografts used as surgical barriers. These products are sold to hospitals, ambulatory surgery centers, and physician offices for clinical treatment.
SERA
2nd
Sera Prognostics
$102.09Mn
2.01
+1.52%
-31.86%
The company develops and sells the PreTRM test and maintains a pipeline of biomarker candidates for conditions such as preeclampsia and gestational diabetes, which constitutes the sale of a diagnostic test product.
ICCC
2nd
Immucell
$97.73Mn
10.75
+5.19%
+77.69%
The company sells the California Mastitis Test, which is used for the on-farm detection of udder inflammation, fitting the description of clinical diagnostic tests and assays.
MLKMF
2nd
Waldencast
$96.96Mn
0.85
+0.00%
-55.03%
The company has entered the aesthetics market through the launch of hyaluronic acid injectable fillers under the Saypha brand, which are therapeutic/surgical medical devices.
LUCD
2nd
Lucid Diagnostics
$93.14Mn
0.45
+7.14%
-57.94%
The company sells specimen kits and related consumables, including the EsoCheck Esophageal Cell Collection Device, to healthcare providers who collect samples on site.
JRSH
2nd
Jerash Holdings (US)
$92.71Mn
7.30
-0.68%
+127.41%
The company operates a dedicated unit, Jerash The First Medical Supplies Manufacturing Company Limited, which is specifically focused on the manufacturing and trade of personal protective equipment (PPE) products.
KBLB
2nd
Kraig Biocraft Laboratories
$89.23Mn
0.08
+0.00%
-11.11%
The company specifically targets the medical implant market, selling its biocompatible recombinant silk fibers to medical device manufacturers for use in surgical implants.
STXS
Stereotaxis
$83.17Mn
0.83
-2.35%
-62.95%
Stereotaxis designs and manufactures therapeutic robotic systems for the interventional laboratory, specifically the Genesis RMN and GenesisX RMN platforms used for cardiac ablation. These are regulated medical devices used to steer catheters and guidewires during surgical procedures.
VANI
2nd
Vivani Medical
$77.19Mn
1.01
+3.06%
-25.74%
Through its subsidiary Cortigent, Inc., the company develops neurostimulation systems aimed at helping patients recover critical body functions, which are therapeutic medical devices.
NRXS
Neuraxis
$75.94Mn
5.50
-4.35%
+134.04%
Neuraxis designs and manufactures therapeutic medical devices, specifically the IB-Stim stimulator for abdominal pain and the RED rectal expulsion device. These are cleared medical devices sold to healthcare providers for clinical use in treating gastrointestinal disorders.
RTGN
RetinalGenix Technologies
$75.19Mn
3.99
+0.00%
+24.69%
The company's core revenue strategy centers on the sale of DNA/GPS laboratory-developed genetic testing kits and the development of the RetinalCam imaging device for screening and monitoring eye health. These products are clinical diagnostic tools sold to patients and healthcare providers to identify biomarkers and disease states.
OM
Outset Medical
$70.40Mn
3.73
-3.37%
-23.88%
Outset Medical designs and manufactures the Tablo Hemodialysis System, which is a therapeutic medical device used for dialysis. The company generates revenue from the sale and lease of these consoles to hospitals, clinics, and home care programs.
COCH
Envoy Medical
$70.33Mn
6.74
-1.03%
+921.21%
Envoy Medical designs and manufactures implantable hearing devices, specifically the Esteem FI AMEI active middle ear implant and the investigational Acclaim CI cochlear implant. These are therapeutic surgical implants sold to surgeons, audiologists, and clinics.
IMDX
Insight Molecular Diagnostics
$69.81Mn
2.14
-7.36%
-72.74%
The company develops and commercializes test kits, such as the GraftAssureIQ and GraftAssureDx IVD, which allow hospitals and laboratories to perform molecular diagnostic testing in-house. Its revenue model is based on the sale of these diagnostic kits and the associated reagents used on digital PCR instruments.
MBOT
Microbot Medical
$65.82Mn
0.98
-4.85%
-50.75%
Microbot Medical designs and manufactures the LIBERTY Endovascular Robotic Surgical System, which is a robotic device used for minimally invasive endovascular procedures. The company sells this therapeutic robotic platform and associated components to hospitals and interventional radiology centers.
VATE
2nd
Innovate
$63.06Mn
4.55
-6.95%
-18.75%
The Life Sciences segment commercializes medical and aesthetic technologies, specifically through R2 Technologies' Glacial Rx system and Genovel Orthopedics' knee osteoarthritis treatments.
LNSR
Lensar
$61.47Mn
5.00
+6.38%
-51.22%
Lensar designs and manufactures therapeutic surgical medical devices, specifically the LENSAR Laser System and ALLY Robotic Cataract Laser System for cataract treatment. These products are sold to hospitals, ambulatory surgery centers, and physician practices for use in ophthalmic surgery.
CNXU
Conexeu Sciences
$59.73Mn
2.18
+0.00%
—
Conexeu Sciences designs and manufactures the CXU™ extracellular-matrix scaffold, which it intends to commercialize as medical devices for wound care, facial rejuvenation, and large-volume augmentation. The company specifically targets FDA 510(k) clearance for device-class indications to serve hospitals, burn centers, and aesthetic clinics.
MDNC
Medinotec
$58.78Mn
5.00
+0.00%
+0.00%
Medinotec designs and manufactures therapeutic and surgical medical devices, specifically tracheal dilation devices and coronary catheters. Its revenue is derived from the sale of products such as the Trachealator and the Cape Cross PTCA catheter to hospitals and clinics.
AZR
2nd
Azora Therapeutics, Inc. (DE)
$58.43Mn
4.09
+9.36%
-48.88%
The company develops and utilizes a companion diagnostic genetic test to identify patients likely to respond to its lead drug candidate, AD04.
HYPR
Hyperfine
$57.42Mn
0.63
-7.35%
-40.00%
Hyperfine manufactures and sells the Swoop® system, which is a portable ultra low field magnetic resonance brain imaging scanner used for clinical diagnosis. The company generates revenue from the sale of these diagnostic instruments and recurring software service and support agreements.
RFL
2nd
Rafael Holdings
$55.50Mn
1.08
-1.82%
-14.29%
The company owns Rafael Medical Devices, which designs and sells the VECTR System and related orthopedic instruments for minimally invasive ligament and fascia release procedures.
POSC
Positron
$54.28Mn
1.64
-2.96%
+1.23%
Positron designs, manufactures, and sells PET and PET-CT imaging systems, which are clinical diagnostic equipment used for molecular imaging in cardiology, oncology, and neurology. Revenue is generated from the sale of these systems and associated reagents/services, fitting the description of diagnostic equipment.
NSPR
InspireMD
$54.18Mn
0.64
-16.88%
-65.78%
InspireMD designs and manufactures therapeutic medical devices, specifically the CGuard and CGuard Prime carotid embolic prevention systems. These products are self-expandable nitinol stents used in surgical procedures to treat carotid artery disease.
AURX
Nuo Therapeutics
$52.96Mn
1.09
+0.00%
-52.61%
Nuo Therapeutics designs and manufactures the Aurix System, a point-of-care medical device used to produce platelet-based therapy for chronic wound care. The company generates revenue from the direct sale of these proprietary devices to healthcare providers.
JANL
2nd
Janel
$51.01Mn
43.00
+0.00%
+34.38%
The Life Sciences segment manufactures and distributes antibodies and research and diagnostic reagents for academic, non-profit, and commercial customers, which are tools used for life-sciences research.
RNXT
RenovoRx
$50.12Mn
1.04
-10.34%
+7.22%
RenovoRx generates its current revenue from the sale of the RenovoCath device, a FDA-cleared local drug delivery system used for temporary vessel occlusion and chemotherapeutic drug infusion. Its customers are U.S. cancer centers and hospitals that purchase these therapeutic medical devices.
MYO
Myomo
$49.72Mn
1.24
+2.48%
+53.09%
Myomo designs and manufactures the MyoPro product line, which consists of myoelectric-controlled upper limb braces or orthoses. These are therapeutic medical devices used to support paralyzed arms and improve functional activities of daily living.
VASO
Vaso
$49.29Mn
0.28
-3.45%
+154.55%
Vaso designs and manufactures proprietary medical devices, specifically the Biox series Holter monitors, ambulatory blood pressure recorders, and EECP therapy systems for ischemic heart disease. These are therapeutic and monitoring devices sold to hospitals and clinics.
ECOR
electroCore
$48.17Mn
5.25
-0.76%
-8.06%
electroCore designs and manufactures prescription medical devices, specifically the gammaCore handheld vagus nerve stimulation device and the Quell Fibromyalgia wearable neuromodulation device. These products are FDA-cleared for treating primary headache and fibromyalgia symptoms.
TELA
TELA Bio
$47.31Mn
0.82
-4.65%
-26.13%
TELA Bio designs and manufactures therapeutic medical devices for soft tissue reconstruction, specifically the OviTex and OviTex PRS reinforced tissue matrices used in hernia repair and plastic surgery. These products are implanted during surgical procedures to reinforce soft tissue, fitting the description of surgical medical devices.
SGMOQ
2nd
Sangamo Therapeutics
$45.57Mn
0.11
+0.00%
-76.60%
The company explicitly expects to receive additional income from licensing its technology to other industries, specifically mentioning research reagents.
QTEX
QTREX Quantum
$44.94Mn
1.25
+5.04%
+31.58%
The company designs and manufactures therapeutic medical devices for life support, specifically the INSPIRA ART100 cardiopulmonary bypass system and the VORTX orbiting blood oxygenation device. These are surgical/treatment devices used in hospitals to replace invasive mechanical ventilation.
POCI
Precision Optics Corporation
$44.62Mn
5.23
+4.60%
+8.28%
The company designs and manufactures therapeutic medical devices, specifically endoscopes, endocouplers, and digital imaging endoscopes used in minimally invasive surgical procedures. These products are sold to established and emerging medical device companies.
HBIO
Harvard Bioscience
$42.94Mn
9.39
+1.84%
+61.90%
Harvard Bioscience develops and manufactures instruments, reagents, and consumables for life-sciences research, such as spectrophotometers, amino acid analyzers, and electroporation systems. Its products are sold to academic institutions and pharmaceutical companies for use in early discovery and bioproduction.
ARAY
Accuray
$42.06Mn
2.80
-9.09%
+152.25%
Accuray designs and manufactures therapeutic medical devices, specifically the CyberKnife robotic system and the Radixact and Helix radiation delivery platforms. These systems are used for radiation treatments in oncology, neurology, and endocrine disorders, fitting the description of therapeutic and surgical medical devices.
MDAI
Spectral AI
$41.84Mn
1.30
-3.70%
-21.21%
Spectral AI develops the DeepView System, which is a clinical diagnostic platform combining multispectral imaging and AI algorithms to predict wound healing. The company sells both the imaging device (hardware) and the associated diagnostic software to hospitals and burn centers.
QUCY
Quantum Cyber
$40.12Mn
0.63
+12.50%
-56.85%
Mainz Biomed manufactures and sells the ColoAlert in vitro diagnostic test, which combines a fecal immunochemical test and PCR analysis, to clinical laboratories and hospitals. The company's revenue is generated through the sale of these diagnostic tests and associated consumables rather than performing the tests itself.
HYPD
2nd
Hyperion Defi
$39.84Mn
2.58
-5.15%
-48.09%
The company is developing the Optejet ophthalmic liquid delivery device, which is a therapeutic medical device designed to deliver topical ocular medications via a micro droplet spray to patients and clinics.
PRPO
2nd
Precipio
$39.68Mn
22.13
-4.82%
+13.37%
The company's Products Division commercializes proprietary diagnostic assays and kits, such as HemeScreen and IV-Cell, which are sold as products to external clinical laboratories.
CCEL
2nd
Cryo Cell International
$39.43Mn
4.89
-9.11%
+19.56%
The company manufactures and sells the PrepaCyte® CB Processing System, which is described as a 510(k) cleared Class II medical device used to process stem cells.
ALPS
Alps
$39.27Mn
1.18
+0.85%
+66.20%
Alps Life Sciences Inc is engaged in the research, development, and commercialization of life sciences products and services, serving research institutions, laboratories, and biotechnology firms. This aligns with the provision of tools and reagents for life-sciences research and bioproduction.
UG
2nd
United Guardian
$38.87Mn
8.46
-1.97%
+37.12%
The company produces medical lubricants sold directly to manufacturers of medical devices, such as catheter and surgical instrument producers, which accounts for 20% of total sales.
NYXH
Nyxoah
$38.72Mn
0.90
+0.00%
-83.05%
Nyxoah designs and manufactures the Genio system, which is an implantable hypoglossal neurostimulator used for the surgical treatment of Obstructive Sleep Apnea. The company generates revenue from the sale of these therapeutic medical devices to hospitals and sleep centers.
SRTS
Sensus Healthcare
$38.36Mn
2.33
-27.64%
-47.76%
Sensus Healthcare designs and manufactures therapeutic medical devices, specifically the SRT 100, SRT 100 plus, and SRT 100 Vision systems used for non-invasive treatment of skin cancer. These are radiation therapy systems sold to dermatology practices and radiation oncology departments.
PAVM
PAVmed
$38.15Mn
1.63
+24.43%
-84.65%
PAVmed's Lucid Diagnostics subsidiary sells the EsoGuard esophageal DNA test and the EsoCheck cell collection device to healthcare providers for the early detection of cancer. Revenue is generated from the sale of these diagnostic products and services, reimbursed by insurers and government programs.
XTNT
Xtant Medical Holdings
$37.87Mn
0.27
-3.57%
-59.09%
Xtant Medical Holdings designs and manufactures therapeutic and surgical medical devices, specifically spinal implant fixation systems including cervical plating, thoracolumbar pedicle screw systems, and interbody spacers. These products are sold to hospitals and surgery centers for use by orthopedic spine surgeons and neurosurgeons.
AVLN
2nd
Avalyn Pharma
$37.32Mn
30.28
-1.01%
—
The company utilizes and has an exclusive license to the PARI eRapid nebulizer system, creating drug-device combinations to deliver medication directly to the lungs.
ELUT
Elutia
$36.41Mn
0.82
-6.82%
+10.81%
Elutia designs and manufactures therapeutic medical devices, specifically biomatrix products for surgical reconstruction. Its cardiovascular products, such as ProxiCor and VasCure, have received 510(k) clearance as medical devices for cardiac tissue repair and vascular reconstruction.
NMAD
2nd
Nomad Power Solutions
$36.23Mn
2.35
-36.49%
-45.35%
Through its majority ownership of Liora Technologies Europe Ltd., the company is developing electronically controlled proton therapy systems for treating tumors, which are therapeutic medical devices.
NEPH
Nephros
$33.15Mn
3.05
-7.85%
-31.00%
Nephros designs and manufactures FDA 510(k) cleared Class II medical devices, specifically microfilters and ultrafilters used in hospitals and dialysis centers to prevent waterborne pathogen transmission and ensure ultrapure dialysate quality.
SY
2nd
So-Young International
$31.14Mn
2.02
+4.12%
-44.35%
Through its subsidiary Wuhan Miracle, the company designs and manufactures laser and photonic devices and surgical lasers sold to third-party clinics and hospitals.
RPID
Rapid Micro Biosystems
$29.55Mn
0.65
-2.99%
-85.43%
Rapid Micro Biosystems sells the Growth Direct platform, which is an automated microbial testing system using high-speed imaging and vision algorithms for clinical/quality control diagnosis. Revenue is generated from the sale of these diagnostic instruments and the proprietary consumables and reagents required to run them.
INFU
2nd
InfuSystem Holdings
$29.44Mn
14.70
-0.41%
+44.69%
The company generates significant revenue from the sale and rental of disposable supply kits, chemotherapy infusion supplies, and wound care products, which are medical consumables.
RMTI
Rockwell Medical
$27.92Mn
7.03
-4.74%
-22.75%
Rockwell Medical manufactures and sells hemodialysis concentrates (liquid and dry acid and bicarbonate) and ancillary supplies like cleaning agents and salts. These are consumables used in dialysis machines, which fits the description of medical supplies and consumables.
QTI
Qt Imaging Holdings
$27.58Mn
1.88
-8.74%
-68.72%
The company designs and manufactures the QT Breast Scanner, as well as developing scanners for orthopedic and infant imaging. These are therapeutic and surgical medical devices used by healthcare providers for diagnostic imaging.
ZJYL
Jin Medical International
$27.40Mn
3.50
-9.56%
-32.69%
Jin Medical International designs and manufactures therapeutic and surgical medical devices, specifically manual and electric wheelchairs and related components, which account for the majority of its revenue (78.4% in fiscal 2025). These products are sold to dealers who distribute them to hospitals, rehabilitation centers, and individual consumers.
MLSS
Milestone Scientific
$27.18Mn
0.30
+3.45%
-21.05%
The company's primary revenue and operational focus is on its Dental Products segment, specifically the CompuDent and STA Single Tooth Anesthesia Systems sold to dental practitioners and groups. This aligns with the H-09 category for companies that make dental products and equipment.
INIS
2nd
Radnostix
$26.46Mn
0.05
+0.00%
-37.50%
The company has a dedicated Medical Devices segment that develops and distributes products such as the EasyFill Automated Capsule System and the RadVent line of lung imaging systems.
BEAT
HeartBeam
$25.33Mn
0.40
+0.00%
-74.52%
HeartBeam designs and manufactures the HeartBeam System, which is an FDA-cleared cable-free ambulatory 12L ECG recording device used for arrhythmia assessment. This is a therapeutic and surgical medical device used for clinical diagnostics outside of healthcare facilities.
BLGO
2nd
Biolargo
$23.01Mn
0.07
+0.00%
-58.82%
The Clyra Medical Technologies segment develops and markets antimicrobial and wound care products based on an iodine-based platform for use in healthcare settings, hospitals, and dental clinics.
TLSI
TriSalus Life Sciences
$22.75Mn
2.43
-3.57%
-44.65%
TriSalus designs and manufactures the FDA-cleared TriNav Infusion System, a medical device used by interventional radiologists for embolization procedures. The company's primary revenue is generated from the sale of this therapeutic device and its variants, such as TriNav FLX and TriNav XP.
NNOX
Nano-X Imaging
$22.27Mn
0.32
+0.00%
-89.04%
The company develops and sells the Nanox. ARC hardware system, which is a digital X-ray source used for medical imaging. Its primary business is the sale of this diagnostic equipment to hospitals, clinics, and imaging centers.
CPHI
2nd
China Pharma Holdings
$21.07Mn
0.52
-7.14%
-65.79%
The company manufactures and sells medical supplies and consumables, specifically medical masks and related personal protective equipment.
TOMZ
2nd
TOMI Environmental Solutions
$20.52Mn
2.52
+9.57%
+3.70%
The company provides disinfection solutions specifically for the Hospital-Healthcare segment, targeting operating rooms and pharmacies to combat healthcare-associated infections, which falls under medical supplies and consumables.
ANGO
Angiodynamics
$20.14Mn
11.87
-0.92%
-3.50%
AngioDynamics designs and manufactures therapeutic and surgical medical devices, including the Auryon Atherectomy System, NanoKnife ablation platforms, and VenaCure EVLT laser systems. These products are sold to hospitals and clinics for treating cardiovascular disease and cancer.
BSEM
BioStem Technologies
$20.14Mn
1.05
-19.23%
-74.64%
BioStem Technologies manufactures and sells therapeutic medical devices in the form of placenta-derived tissue allografts used as protective barriers for wound care and surgical applications. Its product lines, such as Neox, Clarix, and Catalyze, are used in orthopedic, general, and cardiovascular surgery to support tissue repair and regeneration.
RDGL
Vivos
$19.79Mn
0.04
+0.00%
-55.56%
Vivos designs and manufactures the RadioGel and IsoPet devices, which are described as yttrium 90 based precision radionuclide therapy devices for treating solid tumors. These are therapeutic medical devices used by physicians and veterinarians to deliver localized beta radiation.
CELU
2nd
Celularity
$18.45Mn
0.63
-7.35%
-60.38%
The company generates significant revenue from the sale of commercial biomaterial products and allografts, such as Biovance and Interfyl, used by hospitals and wound-care providers for soft-tissue repair.
PLRZ
Polyrizon
$17.53Mn
10.90
-0.82%
+135.93%
Polyrizon develops innovative medical device hydrogels delivered as nasal sprays that form a physical shield containment barrier in the nasal cavity. This product is described as a medical device designed to block viruses and allergens from contacting epithelial tissue.
CRVW
CareView Communications
$17.52Mn
0.03
-25.00%
+0.00%
CareView designs and manufactures therapeutic and surgical medical devices, specifically high-definition cameras, two-way audio systems, and LCD displays used for patient video monitoring. These products are sold as hardware components including the CareView Controller and SitterView Monitor to hospitals and healthcare facilities.
CVRX
CVRx
$17.38Mn
0.61
-3.17%
-93.15%
CVRx designs and manufactures the Barostim system, which consists of an implantable pulse generator and stimulation lead used to treat heart failure. These are therapeutic medical devices sold to hospitals and cardiac centers.
DQWS
2nd
DSwiss
$16.55Mn
0.08
+0.00%
+166.67%
The company explicitly generates revenue from the sale of medical consumable supplies to its clients.
RVP
Retractable Technologies
$16.47Mn
0.55
-1.79%
-32.10%
Retractable Technologies manufactures and markets medical supplies and consumables, specifically the VanishPoint, Patient Safe, and EasyPoint lines of retractable syringes and needles. These products are disposable injection devices sold to hospitals, clinics, and long-term care facilities.
VRXA
2nd
Veraxa Biotech AG - Post de-SPAC
$16.07Mn
1.11
-3.48%
-89.43%
The company operates the Hitmaster Microfluidics Platform, which provides high-throughput antibody discovery, single-cell analysis, and precision sorting of biological particles for research and diagnostic applications.
SNWV
SANUWAVE Health
$15.66Mn
1.82
+15.19%
-94.58%
Sanuwave designs and manufactures the UltraMIST system, a noninvasive ultrasound device used to treat acute and chronic wounds. This is a therapeutic medical device used by clinicians to stimulate tissue repair and regeneration.
LFWD
Lifeward
$15.42Mn
4.02
-28.47%
-35.68%
Lifeward designs and manufactures therapeutic medical devices, specifically the ReWalk exoskeleton suite, the ReStore exo suit, and the AlterG anti-gravity system. These products are used for physical rehabilitation and recovery for patients with spinal cord injuries and stroke.
ALLR
2nd
Allarity Therapeutics
$15.12Mn
0.95
+4.40%
-20.17%
The company develops and sells the Drug Response Predictor (DRP®) platform, which creates cancer drug-specific companion diagnostics to identify patients likely to benefit from therapy. This platform has supported FDA Investigational Device Exemption (IDE) applications for stenoparib and Liposomal CisPlatin.
PMI
Picard Medical
$14.86Mn
7.23
-4.11%
-94.07%
Picard Medical designs and manufactures the SynCardia Total Artificial Heart (TAH), which is a fully implantable therapeutic medical device used to replace heart ventricles. The company generates revenue from the sale of these implantable units and external pneumatic drivers like the Companion 2 and Freedom Driver to hospitals.
DRIO
2nd
DarioHealth
$14.11Mn
1.26
-23.64%
-87.30%
DarioHealth sells FDA-cleared hardware devices that generate continuous physiological data as part of its integrated solution. These are medical-grade regulated wearables/devices used for clinical monitoring of chronic conditions.
BNGO
Bionano Genomics
$13.99Mn
1.00
-3.85%
-31.97%
Bionano Genomics sells optical genome mapping instruments like the Saphyr and Stratys systems, along with the consumables and reagents required to operate them. These products are sold to academic research institutions and biotechnology companies for life-sciences research and genomic analysis.
DYAI
2nd
Dyadic International
$13.23Mn
0.33
-5.71%
-63.74%
The company sells life science reagents such as albumin, transferrin, and DNase I, and serves life science researchers and diagnostic manufacturers.
ALRTF
ALR Technologies SG
$12.91Mn
0.02
+0.00%
+0.00%
The company sells the 'Diabetes Solution' and 'GluCurve Pet CGM' products, which are FDA-cleared diagnostic systems that collect and analyze blood glucose data to provide clinical insights. These products are sold as diagnostic equipment and tests to healthcare providers, hospitals, and veterinary clinics.
BCDA
2nd
BioCardia
$12.57Mn
0.83
+1.22%
-34.13%
The company develops and optimizes specialized catheter-based delivery systems designed for precise, minimally invasive intramyocardial delivery of cells or biologics. These are therapeutic medical devices engineered to enhance procedural accuracy and safety.
FEMY
Femasys
$12.38Mn
1.43
+2.14%
-91.35%
Femasys designs and manufactures therapeutic and surgical medical devices for women's health, such as FemBloc for non-surgical permanent contraception and FemaSeed for intrauterine insemination. Its revenue is generated from the sale of these medical devices to healthcare providers like gynecologists and reproductive endocrinologists.
GUTS
Fractyl Health
$11.94Mn
0.90
+11.11%
-19.64%
The company's lead product candidate, Revita, is a balloon catheter used for hydrothermal ablation of the duodenal lining, which is a therapeutic medical device. The business model focuses on selling this device to physicians, hospitals, and ambulatory surgery centers for use in outpatient procedures.
IRIX
Iridex
$11.69Mn
0.67
-4.29%
-24.72%
IRIDEX designs and manufactures therapeutic laser consoles and delivery devices used to treat glaucoma and retinal diseases. These are surgical medical devices sold to ophthalmologists, hospitals, and ambulatory surgical centers.
MODD
Modular Medical
$10.97Mn
1.97
+16.57%
-86.32%
Modular Medical designs and manufactures therapeutic medical devices, specifically the MODD1 and Pivot insulin pumps for patients with diabetes. These are regulated wearable treatment devices intended for clinical use.
ACH
2nd
Accendra Health
$10.00Mn
0.13
-7.14%
-95.56%
The company generates significant revenue from the sale of medical supplies and consumables, specifically citing ostomy pouches, advanced wound dressings, and urinary catheters.
COSM
2nd
Cosmos Health
$9.71Mn
3.24
+1,442.86%
+343.84%
The company's business profile explicitly states that it produces medical devices as part of its diversified healthcare group.
SINT
Sintx Technologies
$9.30Mn
1.35
-12.34%
-55.88%
SINTX designs and manufactures therapeutic medical devices, specifically interbody spinal fusion implants and foot and ankle osteotomy wedges. These products are sold directly to hospitals and surgical centers or through OEM partnerships.
PLSM
Pulsenmore
$8.97Mn
1.38
-6.12%
—
Pulsenmore designs and manufactures portable ultrasound devices, such as the Pulsenmore ES and FC, which are used for diagnostic imaging of fetal heartbeats and ovarian follicles. The company generates revenue from the sale of these diagnostic machines and associated services to healthcare organizations like Clalit and Sheba Medical Center.
ASTC
2nd
Astrotech
$8.83Mn
4.15
-2.58%
+26.52%
Through BreathTech Corporation, the company develops the BreathTest 1000 for disease screening via volatile organic compound metabolites, collaborating with clinical entities like the Cleveland Clinic Foundation.
HSCS
HeartSciences
$8.28Mn
2.12
-6.19%
-31.39%
HeartSciences develops and sells the MyoVista wav ECG device and AI ECG algorithms specifically for the clinical diagnosis of cardiac dysfunction and heart conditions. The company's revenue model is based on the sale of these diagnostic instruments and the recurring fees for the AI-driven diagnostic analysis.
AWHL
2nd
Aspira Women's Health
$7.93Mn
0.17
+6.25%
-65.31%
The company develops and commercializes noninvasive diagnostic assays and AI-powered tests for gynecologic diseases, such as the FDA-cleared Ova1 and Overa tests.
AZIO
2nd
Azio Ai Holdings
$7.66Mn
0.56
-1.75%
-51.72%
The company operates a medical supplies segment that generates revenue from the delivery of medical gowns to a related party and the federal government.
AMS
2nd
American Shared Hospital Services
$7.28Mn
1.09
-2.68%
-51.34%
The company generates revenue from the sale and leasing of stereotactic radiosurgery and advanced radiation therapy equipment, such as Gamma Knife and proton therapy units, to hospitals and clinics.
POAS
2nd
Phaos Technology Holdings (Cayman)
$6.88Mn
3.27
+9.36%
-15.06%
The company sells the PT-Biology (PT-B) series and other super-resolution imagers to R&D institutions and biomedical service providers for research and innovation activities. These products serve as life-sciences research tools for observing details beyond the conventional optical limit.
EBRCZ
EBR Systems
$6.76Mn
0.08
+0.00%
-86.67%
EBR Systems designs and manufactures the WiSE CRT System, which is an implantable cardiac pacing system used to correct heart rhythm conditions. The system consists of therapeutic and surgical medical devices including an implantable electrode, a subcutaneous transmitter, and a delivery catheter.
NDRA
ENDRA Life Sciences
$6.73Mn
4.49
-3.02%
-31.66%
ENDRA develops the Thermo-Acoustic Enhanced Ultrasound (TAEUS) platform, which is a clinical diagnostic tool used to measure liver fat as a biomarker for metabolic diseases. The company sells the diagnostic capability via direct product sales, subscriptions, and licensing to OEMs, positioning it as a point-of-care alternative to MRI scans.
NMTC
Neuroone Medical Technologies
$6.53Mn
0.75
+0.00%
-81.57%
NeuroOne designs and manufactures therapeutic and surgical medical devices, specifically the OneRF Brain Ablation System and OneRF TN Ablation System for lesion creation and trigeminal neuralgia treatment. These are surgical instruments used for ablation and stimulation in brain-related conditions.
RGNT
Regentis Biomaterials
$6.42Mn
1.24
-0.80%
—
Regentis Biomaterials develops GelrinC, a hydrogel implant and the Stelar delivery device, which are therapeutic medical devices used for treating articular cartilage defects in the knee. The company's target customers are hospitals, orthopedic surgery centers, and surgeons who perform these surgical procedures.
SCND
Scientific Industries
$6.32Mn
0.53
+3.92%
-14.52%
Scientific Industries designs and manufactures benchtop laboratory equipment and bioprocessing systems, such as biomass monitoring sensors and moisture analyzers, sold to universities and pharmaceutical companies for research. These products, including the DOTS brand platform and Torbal balances, are classic life-sciences research tools and bioprocessing supplies.
ADMT
Adm Tronics Unlimited
$6.08Mn
0.09
-10.00%
-18.18%
The company develops and manufactures electronic technologies for non-invasive, electrotherapeutic, and diagnostic medical devices at an FDA-Registered Medical Device Manufacturing facility. It sells these proprietary electronic medical devices and provides contract manufacturing for other medical device manufacturers.
CLGN
2nd
CollPlant Biotechnologies
$5.97Mn
4.66
+17.68%
-75.34%
The company manufactures and sells medical devices for implantation and wound care, specifically citing the VergenixSTR product sold to clinics and hospitals.
CDIO
Cardio Diagnostics Holdings
$5.59Mn
1.89
+1.07%
-44.41%
The company develops and sells clinical diagnostic tests such as Epi+Gen CHD and PrecisionCHD, which are used for the early detection and risk assessment of cardiovascular diseases. These products are sold as diagnostic assays to healthcare providers and health systems.
SNOA
Sonoma Pharmaceuticals
$5.51Mn
1.09
-6.84%
-69.21%
Sonoma Pharmaceuticals manufactures medical supplies and consumables, specifically stabilized hypochlorous acid products for wound care, eye care, and dermatological conditions. These products are sold as office dispense items and consumables to hospitals, physicians, and clinics.
INBS
Intelligent Bio Solutions
$5.45Mn
1.76
-9.28%
-75.45%
The company manufactures and sells the Intelligent Fingerprinting Drug Screening System, which consists of portable DSR Plus readers and single-use cartridges for point-of-care drug detection. This matches the description of in-vitro diagnostic analysers and point-of-care testing platforms.
AEMD
Aethlon Medical
$5.33Mn
5.29
-5.20%
-77.68%
Aethlon Medical develops the Hemopurifier, which is described as a clinical stage immunotherapeutic device designed to remove pathogens and vesicles from the bloodstream. This fits the description of a therapeutic medical device used for treatment in oncology and viral infections.
USAQ
2nd
QHSLab
$5.26Mn
0.35
+29.63%
+118.75%
The company sells the AllergiEnd product line, which consists of FDA-cleared, disposable, single-use allergy skin test applicators and matching test trays used for clinical diagnostic testing of allergens.
RSCF
Reflect Scientific
$5.14Mn
0.06
+0.00%
+20.00%
Reflect Scientific manufactures and sells specialized equipment for the life science market, specifically ultra-low temperature freezers and blast freezers used for the storage of DNA, RNA, and proteins. These products are sold to universities, government and private research facilities, and biotechnology companies for bioproduction and research purposes.
STME
Stimcell Energetics
$4.86Mn
0.23
-23.33%
-52.08%
Stimcell Energetics designs and manufactures the eBalance® Pro System for healthcare professionals and the eBalance® Home System for consumers, both of which are microcurrent electrical therapy devices. These products are described as Class II Medical Devices used for pain relief and managing health complications like insulin sensitivity and high blood pressure.
TANAF
Tian'an Technology
$4.55Mn
0.10
+25.00%
-88.89%
The company's primary revenue driver is the sale of graphene-based far infrared therapy devices, including energy rooms, heating blankets, and moxibustion instruments, which are designed for therapeutic benefits like pain relief and muscle relaxation.
ACON
2nd
Aclarion
$4.50Mn
1.56
-0.64%
-74.63%
The company provides the NOCISCAN MRS exam protocol and diagnostic technology used by imaging centers to perform clinical diagnostic tests for painful intervertebral discs. Its revenue is derived from payments from imaging centers and third-party payer reimbursements for these diagnostic exams.
BMRA
Biomerica
$4.48Mn
1.36
+3.03%
-45.60%
Biomerica manufactures and sells diagnostic test kits, such as the hp detect and inFoods IBS tests, which analyze specimens to detect diseases and bacteria. These products are sold as diagnostic machines/tests to clinical laboratories and point-of-care settings, fitting the H-08 profile of selling the test rather than performing the service.
XAIR
Beyond Air
$4.43Mn
2.13
-3.18%
-92.55%
Beyond Air designs and manufactures the LungFit® system, a medical device used to generate and deliver nitric oxide for treating pulmonary hypertension and other respiratory conditions. Revenue is primarily generated from the sale of these LungFit® PH devices to hospitals and healthcare providers.
CUPR
Cuprina Holdings (Cayman)
$4.32Mn
1.69
+0.60%
-72.30%
The company's primary revenue driver is the MEDIFLY line, which consists of sterile blowfly larvae bio dressings used in hospitals and clinics for chronic wound management. This product, along with its pipeline of collagen dressings and iodine-based topical antiseptics, falls under medical supplies and consumables.
AIFF
Firefly Neuroscience
$4.32Mn
0.94
-2.08%
-41.25%
Firefly Neuroscience manufactures and sells the FDA 510k cleared Evoke System, which is a diagnostic platform used to capture and analyze EEG and ERP assessments. The company generates revenue from subscriptions that provide clinics with this diagnostic equipment and the associated analytics and reporting platform.
NVNO
enVVeno Medical
$4.29Mn
6.17
-6.09%
-73.00%
enVVeno Medical designs and manufactures implantable medical devices, specifically the surgical VenoValve and the transcatheter enVVe System, to treat chronic venous insufficiency. These products are described as Class III implantable devices intended for use by vascular surgeons and interventional radiologists.
MHUAF
Meihua International Medical Technologies
$4.19Mn
6.00
+0.00%
-73.91%
The company manufactures and sells a wide array of disposable medical devices and consumables, including gauze bandages, examination gloves, medical masks, and transfusion equipment. These products are explicitly described as disposable medical devices across its Yangzhou Huada, Jiangsu Yada, and Jiangsu Huadong segments.
ADVB
Advanced Biomed
$4.18Mn
2.53
-23.56%
-71.76%
Advanced Biomed develops and sells medical testing equipment for cancer screening and diagnosis, specifically microfluidic biochips and devices like A+Pre and AC-1000. These products are sold to hospitals and clinical laboratories as diagnostic platforms and assays.
VNRX
Volitionrx
$4.16Mn
0.22
+15.79%
-96.86%
VolitionRx manufactures and sells clinical diagnostic equipment and tests, specifically the Nu. Q® NETs assay for sepsis and the Nu. Q® Cancer assays for lung cancer. Revenue is generated from the sale of diagnostic kits and reagents to hospital laboratories and clinical institutions.
TRIB
Trinity Biotech
$3.81Mn
6.11
+3.91%
-76.04%
Trinity Biotech develops and manufactures clinical diagnostic equipment and tests, including rapid tests, enzyme linked immunosorbent assays, and molecular diagnostics platforms. It generates revenue from the sale of diagnostic kits, instruments, and reagents to hospitals and clinical laboratories.
ICU
SeaStar Medical Holding
$3.69Mn
0.84
-20.00%
-81.74%
SeaStar Medical designs and manufactures the Selective Cytopheretic Device (SCD), specifically the QUELIMMUNE product, which is a therapeutic extracorporeal synthetic membrane cartridge used to treat critically ill patients. The company generates revenue from the sale of these medical devices to hospitals for use in intensive-care units.
BJDX
Bluejay Diagnostics
$2.92Mn
2.61
+0.38%
-57.90%
Bluejay Diagnostics develops the Symphony technology platform, which consists of a diagnostic analyzer and single-use protein detection cartridges for in vitro diagnostics. The company intends to generate revenue from the sale of these analyzers and the recurring sale of the assays/cartridges used to run the tests.
BDMD
Baird Medical Investment Holdings
$2.77Mn
0.09
-18.18%
-92.97%
The company's primary revenue is derived from the sale of proprietary microwave ablation medical devices, specifically therapeutic apparatus and needles used for treating thyroid nodules and breast lumps. These are therapeutic and surgical medical devices sold to hospitals in China.
GIPL
2nd
Global Innovative Platforms
$2.49Mn
0.05
+0.00%
-93.75%
The company manufactures clinical diagnostic equipment, specifically gas chromatographs and the FROG unit, and sells the associated consumables and reagents required to run these tests.
VYST
2nd
Vystar
$2.46Mn
0.10
+42.86%
+11.11%
The RxAir segment designs and manufactures air purification systems, specifically the RxAir 400, which is cleared as a Class II medical device by the FDA for use in healthcare environments like operating rooms.
AIDX
2nd
20
$2.45Mn
0.20
+0.00%
—
The company sells the BioCheck field test kit for screening suspicious powders for bioterror agents, which is a diagnostic test product sold to customers like fire departments.
MBAI
MBody AI
$2.02Mn
2.01
-2.90%
-83.01%
Check-Cap develops the C Scan system, which consists of an ingestible X-ray emitting capsule (C Scan Cap) and a receiver (C Scan Track) used for clinical diagnostic imaging of the colon. The company sells the diagnostic machine and the associated software (C Scan View) to gastroenterology clinics and hospitals rather than performing the tests itself.
UEEC
United Health Products
$2.02Mn
0.05
+25.00%
-16.67%
The company manufactures and markets CelluSTAT, a patented hemostatic gauze used for superficial wound care. This product is a medical consumable/disposable supply sold to hospitals, clinics, and other point-of-care providers.
ITOC
iTonic Holdings
$1.98Mn
1.98
+2.06%
+224.59%
The company develops and commercializes the FTTPS brachytherapy treatment planning system, which is registered as a Class III medical device. This system is used for radiotherapy planning in hospitals, fitting the description of therapeutic medical devices.
CTSO
Cytosorbents
$1.91Mn
4.87
-9.31%
+626.87%
CytoSorbents designs and manufactures therapeutic medical devices, specifically blood purification cartridges like CytoSorb and the PuriFi hemoperfusion pump, used in intensive care and cardiac surgery.
CODX
Co-Diagnostics
$1.90Mn
0.26
-3.70%
-97.67%
Co-Diagnostics manufactures and sells molecular diagnostic reagent kits and PCR-based tests for infectious diseases like COVID-19 and influenza. The company sells these diagnostic machines and assays to clinical laboratories, hospitals, and public health organizations.
NXGL
2nd
Nexgel
$1.81Mn
3.74
-1.32%
+96.84%
The company has a dedicated Medical Devices segment developing products like the NEXDrape incise surgical drape and NEXDerm adhesive tape for securing lines.
ICCM
IceCure Medical
$1.78Mn
0.73
+4.29%
-96.57%
IceCure Medical designs and manufactures therapeutic medical devices, specifically the ProSense, IceSense3, and XSense cryoablation systems used to ablate tumors. These are surgical treatment devices sold to hospitals, ambulatory surgical centers, and private clinics.
NUWE
Nuwellis
$1.66Mn
4.90
-2.58%
-94.29%
Nuwellis designs, manufactures, and commercializes the Aquadex FlexFlow and Aquadex SmartFlow systems, which are medical devices used for ultrafiltration therapy to remove excess fluid and salt from patients. These systems are therapeutic devices sold to hospitals and healthcare providers for treating heart failure, critical care, and pediatric patients.
AMIX
Autonomix Medical
$1.64Mn
1.37
+0.74%
-91.06%
Autonomix Medical designs and develops therapeutic and surgical medical devices, specifically a catheter-based microchip enabled sensing array and radiofrequency ablation system for treating nerve-related disorders. The company's anticipated revenue model is based on the sale of these devices to hospitals and interventional radiology suites.
HEPA
Hepion Pharmaceuticals
$1.62Mn
0.10
-28.57%
+42.86%
Hepion Pharmaceuticals focuses on the development of diagnostic tools for chronic liver diseases, specifically three products acquired from Cirna Diagnostics, LLC. These assets are described as diagnostic tools that have received CE marking, fitting the description of clinical diagnostic tests and platforms.
VVOS
Vivos Therapeutics
$1.45Mn
0.10
+0.00%
-95.87%
Vivos Therapeutics sells proprietary oral appliances (such as Versa, Vida, and Tooth Positioners) and operates dental service organizations to treat maxillofacial abnormalities. Its core product is a non-surgical dental-based therapy for obstructive sleep apnea and snoring.
ADGM
Adagio Medical Holdings
$1.43Mn
1.93
+6.04%
+135.37%
Adagio Medical Holdings designs and manufactures the vCLAS Cryoablation System, which consists of a catheter and console used for the surgical treatment of cardiac arrhythmias. The company's core business is the development of this therapeutic medical device for use in electrophysiology labs and hospitals.
IVF
2nd
INVO Fertility
$1.37Mn
2.60
-2.99%
-86.97%
The company designs, manufactures, and sells the INVOcell medical device to third-party fertility clinics to enable the intravaginal culture procedure.
VYCO
Vycor Medical
$1.33Mn
0.04
+0.00%
-76.47%
Vycor Medical designs, develops, and markets the ViewSite Brain Access System, a retractable access device used in brain and spine surgeries sold to hospitals and surgical centers. This fits the description of therapeutic and surgical medical devices.
ISCO
2nd
International Stem Cell
$1.28Mn
0.16
+0.00%
+0.00%
Through its Lifeline Cell Technology business, the company sells over two hundred human cell-based items, including primary cells, stem cells, and specialized media, to academic, government, and industrial laboratories.
ESMC
Escalon Medical
$1.26Mn
0.17
-10.53%
+6.25%
Escalon Medical designs and manufactures therapeutic and surgical medical devices for ophthalmic applications, specifically ultrasound-based surgical tools used in cataract and vitreoretinal interventions. The company sells these devices directly to medical institutions and through distributors.
WOK
WORK Medical Technology
$1.24Mn
1.20
-4.00%
-100.00%
The company's primary revenue is derived from the manufacture and sale of disposable medical supplies and consumables, specifically endotracheal tubes, laryngeal mask airways, disposable breathing circuits, and nebulizer kits. These products are explicitly described as Class I and II disposables sold to hospitals and distributors.
NXL
Nexalin Technology
$1.24Mn
1.49
+0.00%
-95.75%
Nexalin designs and manufactures neurostimulation medical devices, specifically the Gen-2 SYNC clinical device and the Gen-3 HALO patient headset, for treating mental health conditions. These are therapeutic medical devices used for brain stimulation, which fits the definition of H-06.
BTCY
Biotricity
$1.20Mn
0.06
+20.00%
-88.89%
Biotricity designs and manufactures therapeutic and surgical medical devices, specifically the Bioflux, Biocore Pro, and Biocore three-lead ECG monitoring systems. These are FDA-cleared medical-grade wearables used for clinical arrhythmia detection and cardiac monitoring.
DHTI
2nd
Dalrada Technology
$1.20Mn
0.01
+0.00%
-75.00%
The company operates Boost Diagnostics, which provides molecular and antibody testing, including Pharmacogenomics and Fitness DNA analysis.
LGMK
LogicMark
$1.17Mn
1.30
+0.00%
-42.22%
LogicMark designs and manufactures therapeutic and surgical medical devices, specifically personal emergency response systems (PERS) like the Guardian Alert 911 Plus and Freedom Alert. These are regulated medical-grade wearables used for fall detection and emergency alerts to enable independent aging.
BBLG
Bone Biologics
$1.15Mn
0.34
-15.00%
-80.00%
Bone Biologics is a medical device company developing NB1, a combination product for spinal fusion and lumbar interbody fusion procedures. Its intended customers are spine surgeons, orthopedic surgeons, and hospitals.
ODYY
Odyssey Health
$1.06Mn
0.01
+0.00%
-85.71%
Odyssey Health develops and intends to market therapeutic and diagnostic medical devices, specifically the CardioMap heart monitoring device and the Save A Life choking rescue device. These products are designed for use by cardiologists, hospitals, and first responders, fitting the description of therapeutic and surgical medical devices.
HCWB
2nd
HCW Biologics
$1.02Mn
0.77
-4.94%
-94.85%
The company commercializes and sells specific reagents, HCW9201 and HCW9206, which are used by partners to improve the manufacturing of CAR T and natural killer cell therapies.
ISPC
iSpecimen
$1.00Mn
0.66
-5.71%
-97.34%
iSpecimen sells human biospecimens, including biofluids, tissues, and living cells, to life science researchers for use in discovery and development. These products are essential reagents and materials for life-sciences research, fitting the description of tools and consumables for bioproduction and research.
OGEN
2nd
Oragenics
$902.39K
0.20
-42.86%
-82.46%
The company designs and develops a proprietary breath-powered intranasal device used to administer its drug candidate. This device is a therapeutic medical device designed to close the soft palate and enhance nasal retention.
JRSS
Jrsis Health Care
$845.99K
0.01
+0.00%
-50.00%
The company designs and manufactures smart terminal hardware for the medical industry, specifically unmanned medicine vending machines and one-stop medicine distribution systems. These are therapeutic and treatment-related devices used by hospitals and pharmacies to deliver medication to patients.
NUMD
Nu-Med Plus
$835.48K
0.01
+0.00%
-66.67%
Nu-Med Plus designs and manufactures therapeutic medical devices, specifically nitric oxide delivery systems including a bedside hospital delivery device, a clinical delivery unit, and a portable rechargeable device. These products are intended for clinical use in intensive care units and medical offices to deliver inhaled nitric oxide therapy.
ITP
2nd
It Tech Packaging
$817.03K
0.06
+0.00%
-75.00%
The company generates revenue from the production and sale of medical face masks, which are medical consumables and disposable supplies.
TRFA
2nd
Trafalgar International
$755.73K
0.76
+1.33%
+68.89%
The company holds an exclusive worldwide license for an eluting transmucosal patch platform, which is a therapeutic medical device used for the noninvasive delivery of cannabinoids across mucosal membranes.
BMGL
2nd
Basel Medical
$743.59K
0.47
-17.54%
-96.89%
The company earns income from the sale of prescribed orthopedic devices to its patients, which constitutes a distinct product-based revenue stream alongside its service fees.
ONCO
Onconetix
$719.93K
3.21
+5.94%
-97.37%
Onconetix sells Proclarix, an in vitro diagnostic test for prostate cancer, to diagnostic laboratories, hospitals, and clinics. The company generates revenue from the sale of this diagnostic assay and its associated proprietary algorithm used to generate risk scores.
BNBX
Bnb Plus
$669.20K
0.08
+0.00%
-97.43%
The company's primary revenue is generated through LineaRx, which sells synthetic DNA templates, RNA production enzymes, and mRNA manufacturing kits to biotechnology firms and research institutions. These products are tools and reagents used for life-sciences research and bioproduction.
SONX
Sonendo
$607.82K
1.28
+0.00%
+392.31%
Sonendo designs and manufactures the GentleWave System, which is specifically indicated for root canal therapy and sold to endodontists and general dentists. Its core business is focused on the dental technology market and the endodontics industry.
PFSA
Profusa
$535.84K
0.45
-2.17%
-99.97%
Profusa designs and manufactures therapeutic and surgical medical devices, specifically injectable hydrogel biosensors like Lumee Oxygen and Lumee Glucose. These are regulated medical devices intended for clinical use in wound care and diabetes management, sold to hospitals and clinics.
PAIYY
2nd
Aesthetic Medical International Holdings
$491.09K
0.01
+0.00%
-92.31%
The company explicitly offers cosmetic dentistry as part of its service portfolio within its general healthcare and other aesthetic medical services segment.
TNON
Tenon Medical
$462.48K
1.41
-21.23%
-96.59%
Tenon Medical designs and manufactures The Catamaran™ SI Joint Fusion System, which is a titanium implant used for sacroiliac joint fusion. This is a therapeutic surgical medical device sold to hospitals and outpatient surgery centers.
FMTOF
2nd
Femto Technologies
$430.56K
0.50
+0.00%
-15.25%
The company develops and commercializes the Sensera device, an AI-powered biofeedback system designed to regulate lubricant flow into female soft tissues for wellness and therapeutic solutions.
RMTG
2nd
Regenerative Medical Technology
$412.17K
0.03
+0.00%
-25.00%
The company generates revenue from the sale of equipment and proprietary kits used by physicians to apply stem cell therapies.
VRAX
Virax Biolabs
$353.32K
0.61
-8.96%
-94.97%
The company focuses on the detection and diagnosis of viral diseases through in vitro diagnostics, specifically developing the ViraxImmune brand for immune profiling tests and assays. It sells diagnostic test kits for respiratory infections, oncology, and cardiac markers to healthcare providers and laboratories.
CYTOF
2nd
Altamira Therapeutics
$326.35K
0.07
+0.00%
-30.00%
The company retains an economic interest in Bentrio, which is explicitly described as being regulated as a Class II medical device by the FDA for the treatment of allergic rhinitis.
RBOT
Vicarious Surgical
$284.97K
0.02
+0.00%
-99.51%
Vicarious Surgical designs and manufactures the Vicarious Surgical System, a robotic platform for minimally invasive abdominal and gynecological procedures. The company's primary product is a therapeutic surgical robot consisting of a surgeon console, patient cart, and instrument arms.
XAGE
2nd
Longevity Health Holdings
$247.53K
0.10
-16.67%
-80.77%
The company develops Bone Healing Accelerant (BHA) and Tissue Healing Accelerant (THA), which are biologic putties and pastes designed for trauma fixation surgeries, spinal fusion, and dental bone grafts.
FOXO
2nd
Foxo Technologies
$241.51K
0.17
+0.00%
-88.67%
Through Vector BioSource Inc., the company sources, preserves, and distributes human biological specimens (blood, serum, tissues, cells) to pharmaceutical and biotechnology firms for research and development.
ECIA
Encision
$168.80K
0.01
+0.00%
-93.75%
Encision designs and manufactures therapeutic and surgical medical devices, specifically Active Electrode Monitoring (AEM) Surgical Instruments and AEM Monitors used in laparoscopic procedures. Its revenue is derived from the sale of these surgical instruments, including scissors, graspers, and dissectors, to hospitals and surgical centers.
VJET
Flyte Aviation
$135.60K
0.49
-7.55%
-97.61%
Catheter Precision designs and manufactures therapeutic and surgical medical devices, specifically the VIVO System for 3D cardiac mapping and the Amigo robotic arm for catheter control. These products are sold to hospitals and electrophysiology labs for use in cardiac ablation procedures.
FEED
ENvue Medical
$123.14K
0.24
-7.69%
-99.57%
The company designs and manufactures therapeutic and surgical medical devices, specifically ultrasound-based products like UroShield for biofilm prevention, PainShield for pain therapy, and the Envizion System for guiding feeding tube placement. These are regulated treatment devices sold to hospitals and distributors.
VBIO
2nd
Valion Bio
$73.01K
0.54
+3.85%
-98.96%
The company maintains a Bioelectronic Medicine program developing non-invasive cervical vagus nerve stimulation devices for neurologic, cardiac, and autoimmune conditions, which are therapeutic medical devices.
SOBR
2nd
SOBR Safe
$48.40K
0.04
+0.00%
-98.41%
The company manufactures the SOBRcheck and SOBRsure devices, which are regulated medical-grade wearables and sensors used for continuous alcohol monitoring and clinical behavioral health tracking.
SIGY
Sigyn Therapeutics
$48.16K
0.03
+0.00%
-98.50%
Sigyn Therapeutics develops medical devices for extracorporeal blood purification, specifically the Sigyn Therapy device and the ImmunePrep, ChemoPrep, and ChemoPure platforms. These are therapeutic devices designed to remove pathogens, toxins, and chemotherapy agents from the bloodstream to treat cancer and infectious diseases.
GCTK
Glucotrack
$36.73K
0.22
-8.33%
-99.74%
Glucotrack designs and develops an implantable continuous blood glucose monitor, which is a therapeutic/surgical medical device. The company's core focus is the development of this intravascular sensor for patients with Type 1 and Type 2 diabetes.
APT
2nd
Alpha Pro Tech
$30.86K
6.16
-0.65%
+41.94%
The company develops and manufactures disposable protective apparel and infection control products such as gowns, lab coats, face masks, and face shields sold into medical and dental markets.
GTHP
Guided Therapeutics
$10.62K
0.11
-8.33%
-50.00%
Guided Therapeutics designs and manufactures the LuViva Advanced Cervical Scan, a medical device used for the noninvasive detection of cervical cancer. The company generates revenue from the sale of these therapeutic/diagnostic systems to distributors and government health programs.
ADTX
2nd
Aditxt
$0.00
0.00
—
-100.00%
Through its Pearsanta segment and Mitomic technology platform, the company develops mitochondrial DNA-based biomarkers and blood-based tests for the early detection of prostate cancer and endometriosis.
ALUR
Allurion Technologies
$0.00
0.00
—
-100.00%
Allurion designs and manufactures the Allurion Smart Capsule, a swallowable intragastric balloon used for weight loss. This is a therapeutic medical device sold to healthcare providers such as clinics and hospitals.
BDPT
2nd
Bioadaptives
$0.00
0.00
—
-100.00%
The company manufactures and sells the Lung Flute, which is explicitly described as a medical device supplied to medical clinics and senior care facilities.
BRGX
Bioregenx
$0.00
0.00
—
-100.00%
The company develops and sells the GlycoCheck™ system, which is explicitly described as a Class I medical device sold to hospitals, academic research institutions, and wellness practitioners.
DROR
Dror Ortho-Design
$0.00
0.00
—
-100.00%
The company develops the ZSmile and Aerodentis systems, which are FDA-cleared medical devices specifically for correcting tooth alignment (malocclusion). Its primary customers are dental professionals, including orthodontists and general dentists, who prescribe these aligners to patients.
EMED
Electromedical Technologies
$0.00
0.00
—
—
Electromedical Technologies designs and manufactures FDA cleared bioelectronic medical devices for pain management, such as those using electrical impulses and vibration. Its revenue is generated primarily from the sale of these therapeutic devices to distributors and healthcare providers.
GVHGF
2nd
Visionary Holdings
$0.00
0.00
—
-100.00%
The company sells life sciences products including collagen probiotic and prebiotic series, gastrointestinal detection tools, and micro-ecological nutritional products.
LUDG
2nd
Ludwig Enterprises
$0.00
0.00
—
-100.00%
The company sells at-home cheek swab collection kits, which are the physical diagnostic tools required to perform its proprietary mRNA-based tests.
RMSL
RemSleep Holdings
$0.00
0.00
—
—
RemSleep Holdings designs and manufactures the DeltaWave CPAP interface, which is a therapeutic medical device used for the treatment of obstructive sleep apnea. The company generates revenue from the sale of these respiratory interfaces to healthcare providers and distributors.
